niacinamide has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 4 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitochondrial disorders are highly heterogeneous conditions characterized by defects of the mitochondrial respiratory chain." | 1.40 | NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease. ( Auwerx, J; Cerutti, R; Dantzer, F; Lamperti, C; Leoni, V; Li, W; Marchet, S; Pirinen, E; Sauve, AA; Schon, EA; Viscomi, C; Zeviani, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Orlandi, I | 1 |
| Vai, M | 1 |
| Zhao, N | 1 |
| Xia, J | 1 |
| Xu, B | 1 |
| Cerutti, R | 1 |
| Pirinen, E | 1 |
| Lamperti, C | 1 |
| Marchet, S | 1 |
| Sauve, AA | 1 |
| Li, W | 1 |
| Leoni, V | 1 |
| Schon, EA | 1 |
| Dantzer, F | 1 |
| Auwerx, J | 1 |
| Viscomi, C | 1 |
| Zeviani, M | 1 |
| Hathorn, T | 1 |
| Snyder-Keller, A | 1 |
| Messer, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Niacin Supplementation on Systemic Nicotinamide Adenine Dinucleotide (NAD+) Metabolism, Physiology and Muscle Performance in Healthy Controls and Mitochondrial Myopathy Patients[NCT03973203] | 15 participants (Actual) | Interventional | 2014-06-01 | Completed | |||
| NiaMIT (NiaMIT_0001) Continuation for Early-stage Mitochondrial Myopathy Patients to Investigate the Effect of Niacin Supplementation on Systemic Nicotinamide Adenine Dinucleotide (NAD+) Metabolism, Physiology and Muscle Performance[NCT04538521] | 3 participants (Actual) | Interventional | 2019-02-11 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for niacinamide and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Assays for Monitoring the Effects of Nicotinamide Supplementation on Mitochondrial Activity in Saccharomyces cerevisiae.
Topics: Aging; Cell Respiration; Dietary Supplements; Membrane Potential, Mitochondrial; Mitochondria; Mitoc | 2020 |
Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via SIRT1-FOXO1/3-PINK1-Parkin-mediated mitophagy.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Brain-Derived Neurotrophic Factor; | 2021 |
NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Electron Transport Complex IV; Energy Metaboli | 2014 |
NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Electron Transport Complex IV; Energy Metaboli | 2014 |
NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Electron Transport Complex IV; Energy Metaboli | 2014 |
NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Electron Transport Complex IV; Energy Metaboli | 2014 |
Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Humans; Huntington Disea | 2011 |