niacinamide has been researched along with Down Syndrome in 2 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pincheira, J | 1 |
| Rodriguez, M | 1 |
| Bravo, M | 1 |
| Navarrete, MH | 1 |
| Lopez-Saez, JF | 1 |
| Monti, D | 1 |
| Troiano, L | 1 |
| Grassilli, E | 1 |
| Agnesini, C | 1 |
| Tropea, F | 1 |
| Barbieri, D | 1 |
| Capri, M | 1 |
| Cristofalo, EA | 1 |
| Salvioli, S | 1 |
| Ronchetti, I | 1 |
2 other studies available for niacinamide and Down Syndrome
| Article | Year |
|---|---|
Defective G2 repair in Down syndrome: effect of caffeine, adenosine and niacinamide in control and X-ray irradiated lymphocytes.
Topics: Adenosine; Adenosine Triphosphate; Caffeine; Child, Preschool; Chromosome Aberrations; Chromosomes, | 1994 |
Cell proliferation and cell death in immunosenescence.
Topics: Adenosine Triphosphate; Adult; Age Factors; Carnitine; Cell Death; Cell Division; Cellular Senescenc | 1992 |