niacinamide has been researched along with Cystic Fibrosis of Pancreas in 2 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Excerpt | Relevance | Reference |
---|---|---|
"Cystic fibrosis is a hereditary disease mainly caused by the deletion of the Phe 508 (F508del) of the cystic fibrosis transmembrane conductance regulator (CFTR) protein that is thus withheld in the endoplasmic reticulum and rapidly degraded by the ubiquitin/proteasome system." | 1.72 | Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing. ( D'Ursi, P; Ford, RC; Fossa, P; Meng, X; Milanesi, M; Orro, A; Padoan, R; Pedemonte, N; Pesce, E; Rondina, A; Rusnati, M; Uggeri, M; Urbinati, C, 2022) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 1 (50.00) | 2.80 |
Authors | Studies |
---|---|
Chung, WJ | 1 |
Goeckeler-Fried, JL | 1 |
Havasi, V | 1 |
Chiang, A | 1 |
Rowe, SM | 1 |
Plyler, ZE | 1 |
Hong, JS | 1 |
Mazur, M | 1 |
Piazza, GA | 1 |
Keeton, AB | 1 |
White, EL | 1 |
Rasmussen, L | 1 |
Weissman, AM | 1 |
Denny, RA | 1 |
Brodsky, JL | 1 |
Sorscher, EJ | 1 |
Fossa, P | 1 |
Uggeri, M | 1 |
Orro, A | 1 |
Urbinati, C | 1 |
Rondina, A | 1 |
Milanesi, M | 1 |
Pedemonte, N | 1 |
Pesce, E | 1 |
Padoan, R | 1 |
Ford, RC | 1 |
Meng, X | 1 |
Rusnati, M | 1 |
D'Ursi, P | 1 |
2 other studies available for niacinamide and Cystic Fibrosis of Pancreas
Article | Year |
---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu | 2016 |
Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing.
Topics: Aminopyridines; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; | 2022 |