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niacinamide and Coronary Heart Disease

niacinamide has been researched along with Coronary Heart Disease in 59 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"We studied the acute haemodynamic dose response of nicorandil, a combined nitrate and potassium channel opener, in patients evaluated for chest pain."9.07Dose-related haemodynamic effects and pharmacokinetics of oral nicorandil in patients evaluated for chest pain. ( Arnold, JM; Hearron, AE; Jungbluth, GL; Kowey, PR; Luderer, JR; Wolf, DL, 1994)
"Patients with stable, effort-induced angina pectoris and a typical combination of anginal pain and ischemic ST depression in exercise tolerance tests were randomized to treatment for 8 weeks with nicorandil (a newly developed antianginal and anti-ischemic drug) or nifedipine."9.07Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study. ( Diderholm, E; Frithz, G; Gudbrandsson, T; Hedbäck, B; Höglund, C; Moelstad, P; Perk, J; Sverrisson, JT; Ulvenstam, G, 1992)
"Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem."7.69Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996)
"The effects of nicorandil, a new antianginal drug, on size of myocardial infarction were studied in anesthetized, open-chest dogs after left anterior descending coronary artery occlusion."7.67Reduction of size of myocardial infarction with nicorandil, a new antianginal drug, after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1988)
" The most often reported adverse event was headache, which was responsible for most of the study withdrawals due to clinical intolerance (9."6.68Nicorandil safety in the long-term treatment of coronary heart disease. ( Darmon, JY; Witchitz, S, 1995)
" Under the assumption that the repetitive administration of nitrates with short dosing intervals might induce the development of tolerance to the nitrate mechanism of action, the t."6.67Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients. ( Döring, G, 1992)
"We studied the acute haemodynamic dose response of nicorandil, a combined nitrate and potassium channel opener, in patients evaluated for chest pain."5.07Dose-related haemodynamic effects and pharmacokinetics of oral nicorandil in patients evaluated for chest pain. ( Arnold, JM; Hearron, AE; Jungbluth, GL; Kowey, PR; Luderer, JR; Wolf, DL, 1994)
"This randomized, double-blind, parallel study compared the anti-anginal effects of nicorandil and atenolol in 37 patients with exercise-induced angina pectoris."5.07A double-blind comparison of a beta-blocker and a potassium channel opener in exercise induced angina. ( Hughes, LO; Lahiri, A; Raftery, EB; Rose, EL, 1993)
"Patients with stable, effort-induced angina pectoris and a typical combination of anginal pain and ischemic ST depression in exercise tolerance tests were randomized to treatment for 8 weeks with nicorandil (a newly developed antianginal and anti-ischemic drug) or nifedipine."5.07Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study. ( Diderholm, E; Frithz, G; Gudbrandsson, T; Hedbäck, B; Höglund, C; Moelstad, P; Perk, J; Sverrisson, JT; Ulvenstam, G, 1992)
"Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem."3.69Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996)
"The effects of nicorandil, a new antianginal drug, on size of myocardial infarction were studied in anesthetized, open-chest dogs after left anterior descending coronary artery occlusion."3.67Reduction of size of myocardial infarction with nicorandil, a new antianginal drug, after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1988)
" The most often reported adverse event was headache, which was responsible for most of the study withdrawals due to clinical intolerance (9."2.68Nicorandil safety in the long-term treatment of coronary heart disease. ( Darmon, JY; Witchitz, S, 1995)
"Nicorandil was found to increase the rate of VO2, increase during the onset of constant work rate exercise, probably as a result of an improved response in cardiac output."2.68Effects of nicorandil on kinetics of oxygen uptake at the onset of exercise in patients with coronary artery disease. ( Adachi, H; Hiroe, M; Kano, H; Koike, A; Korenaga, M; Marumo, F; Miyahara, Y; Shimizu, N; Sugimoto, K; Yajima, T, 1995)
"Nicorandil is an antianginal drug that causes potent coronary vasodilation of both epicardial and resistance vessels."2.68Coronary microvascular response to intracoronary administration of nicorandil. ( Hongo, M; Nakatsuka, T; Sekiguchi, M; Takenaka, H; Uchikawa, S; Watanabe, N, 1995)
"Nicorandil is a hybrid of a nitrate and a potassium channel opener, and has a potent vasodilatory effect on coronary arteries."2.68Effective and safe dose of intracoronary nicorandil in man. ( Fujita, M; Igawa, A; Inouc, H; Miwa, K; Yamanishi, K, 1995)
"Nicorandil and diltiazem were both found to decrease the frequency of anginal attacks and the consumption of nitroglycerin tablets (P < 0."2.67A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris. ( Blin, P; Guermonprez, JL; Peterlongo, F, 1993)
" Under the assumption that the repetitive administration of nitrates with short dosing intervals might induce the development of tolerance to the nitrate mechanism of action, the t."2.67Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients. ( Döring, G, 1992)
" Clinical trials demonstrate that chronic administration of nicorandil can significantly increase exercise tolerance in patients with coronary artery disease."2.38[Anti-angina activity of potassium-channel activators]. ( Ambrosio, G; Chiariello, M; Duilio, C, 1993)
"Nicorandil is a potent vasodilator with antianginal and anti-ischemic properties that acts on both the coronary and the peripheral vascular bed."2.38Acute hemodynamic effects of nicorandil in coronary artery disease. ( Erbel, R; Meyer, J; Treese, N, 1992)
"nicorandil was significant, the 8% increase of isosorbide dinitrate was not."1.28Nicorandil and cardiovascular performance in patients with coronary artery disease. ( MacLeod, D; Suryapranata, H, 1992)
"Nicorandil was administered either intravenously (i."1.28Nicorandil improves postischemic contractile function independently of direct myocardial effects. ( Grover, GJ; Parham, CS; Sleph, PG, 1990)
"Nicorandil, 20 mg, was administered sublingually to 11 consecutive patients and 40 mg to 11 others."1.28Coronary vasodilatory action after nicorandil: a quantitative angiographic study. ( Serruys, PW; Suryapranata, H, 1989)
"Nicorandil was thus considered to produce its antianginal effect primarily by redistribution of coronary blood flow as a result of dilatation of vascular beds and by its antispasmodic action."1.27Effects of nicorandil on coronary circulation in patients with ischemic heart disease: comparison with nitroglycerin. ( Aizawa, T; Kato, K; Ogasawara, K, 1987)
"Nicorandil, 20 mg, was administered sublingually to 11 consecutive patients and 40 mg to 11 others."1.27Coronary vasodilatory action after a single dose of nicorandil. ( De Feyter, PJ; Hugenholtz, PG; Serruys, PW; Suryapranata, H; Verdouw, PD, 1988)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199031 (52.54)18.7374
1990's28 (47.46)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GHIA, G1
MEREU, D1
MACCARINI, PA1
FREZZA, S1
Thormann, J1
Schlepper, M1
Kramer, W1
Gottwik, M1
Abiko, Y2
Nishimura, T1
Sakai, K2
Lamping, KA1
Warltier, DC3
Hardman, HF1
Gross, GJ5
Witchitz, S1
Darmon, JY1
Koike, A1
Hiroe, M1
Yajima, T1
Adachi, H1
Shimizu, N1
Kano, H1
Sugimoto, K1
Miyahara, Y1
Korenaga, M1
Marumo, F1
Hongo, M1
Takenaka, H1
Uchikawa, S1
Nakatsuka, T1
Watanabe, N1
Sekiguchi, M1
Haeusler, G1
Lues, I1
Chiariello, M1
Duilio, C1
Ambrosio, G1
Arnold, JM1
Kowey, PR1
Wolf, DL1
Jungbluth, GL1
Hearron, AE1
Luderer, JR1
Suryapranata, H4
Why, HJ1
Richardson, PJ1
Guermonprez, JL1
Blin, P1
Peterlongo, F1
Raftery, EB1
Lahiri, A1
Hughes, LO1
Rose, EL1
Kato, K2
Miwa, K1
Igawa, A1
Yamanishi, K1
Fujita, M1
Inouc, H1
Takahashi, T1
Takahashi, K1
Kishi-Tanikawa, S1
Tsuchida, K1
Araki, H1
Higuchi, S1
Goldschmidt, M1
Landzberg, BR1
Frishman, WH1
Murayama, S1
Yamakado, T1
Nakano, T1
Takaoka, A1
Nakae, I1
Liu, Q1
Yamamoto, K1
Ito, M1
Kinoshita, M1
Nishikawa, Y1
Kanki, H1
Ogawa, S1
MacLeod, D1
Treese, N1
Erbel, R1
Meyer, J1
Ulvenstam, G1
Diderholm, E1
Frithz, G1
Gudbrandsson, T1
Hedbäck, B1
Höglund, C1
Moelstad, P1
Perk, J1
Sverrisson, JT1
Döring, G1
Ogino, K1
Kinugawa, T1
Noguchi, N1
Kitamura, H1
Matsumoto, T1
Miyakoda, H1
Kotake, H1
Mashiba, H1
Grover, GJ1
Sleph, PG1
Parham, CS1
Mitani, A1
Kinoshita, K1
Fukamachi, K1
Sakamoto, M1
Kurisu, K1
Tsuruhara, Y1
Fukumura, F1
Nakashima, A1
Tokunaga, K1
Ohta, H1
Jinno, Y1
Harada, K1
Ogawa, N1
Fukushima, H1
Nishikori, K1
Kishida, H1
Hata, N1
Kusama, Y1
Iwahara, S1
Sasaki, Y1
Mori, N1
Yasutake, M1
Koumi, S1
Takayama, M1
Munakata, K1
Tsuchioka, Y1
Yamagata, T1
Amioka, H1
Hashimoto, M1
Okamoto, M1
Matsuura, H1
Kajiyama, G1
Chen, SL1
Zhu, MZ1
Feng, XB1
Li, LS1
Zang, YM1
Kambara, H2
Nakamura, Y3
Tamaki, S2
Kawai, C2
Kobayashi, K1
Hakuta, T1
Aizawa, T1
Ogasawara, K1
Pieper, GM3
Ichihara, K2
Kojima, S1
Mori, H1
Abe, S1
Miyamori, R1
Miyazaki, T1
Sakurai, K1
Hattori, S1
Takahashi, M1
Endo, T1
Nejima, J1
Kiuchi, K1
Fujita, S1
Kikuchi, K1
Hayakawa, H1
Okumura, H1
Haneda, T1
Onodera, S1
Gross, G1
Pieper, G1
Farber, NE1
Warltier, D1
Hardman, H1
Coltart, DJ1
Signy, M1
Serruys, PW2
Kempsford, RD1
Hawgood, BJ1
Sassen, LM1
Soei, LK1
Heere, TJ1
van Woerkens, LJ1
Saxena, PR1
Verdouw, PD2
Katagiri, T1
Mochizuki, M1
Umetsu, K1
Hiroshige, J1
Geshi, E1
Konno, N1
Gubachev, IuM1
Vinokur, VA1
Dornichev, VM1
Shimshak, TM1
Preuss, KC1
Brooks, HL1
De Feyter, PJ1
Hugenholtz, PG1
Irié, H1
Korb, H1
Hoeft, A1
Hunneman, DH1
Schraeder, R1
Wolpers, HG1
Hellige, G1
Wren, JC1
Vittori, C1
Borri, P1
Bianchi, V1
Caruzzo, C1
Khalfer, ESh1
Iakusheva, IA1
Katkova, NB1
Loginova, LA1
Ital'ianskaia, IuV1

Reviews

8 reviews available for niacinamide and Coronary Heart Disease

ArticleYear
Therapeutic potential of potassium channel activators in coronary heart disease.
    European heart journal, 1994, Volume: 15 Suppl C

    Topics: Animals; Coronary Disease; Coronary Vessels; Heart; Humans; Muscle, Smooth, Vascular; Niacinamide; N

1994
[Anti-angina activity of potassium-channel activators].
    Cardiologia (Rome, Italy), 1993, Volume: 38, Issue:12 Suppl 1

    Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Humans; Niacinamide; Nicorandil; Potass

1993
Coronary haemodynamics and vasodilatory profile of a potassium channel opener in patients with coronary artery disease.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Administration, Sublingual; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug

1993
A potassium channel opener as monotherapy in chronic stable angina pectoris: comparison with placebo.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Angina Pectoris; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug; Exercise

1993
Haemodynamic and clinical effects of an intravenous potassium channel opener--a review.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Administration, Sublingual; Angina, Unstable; Coronary Circulation; Coronary Disease; Hemodynamics;

1993
Nicorandil: a potassium channel opening drug for treatment of ischemic heart disease.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:7

    Topics: Clinical Trials as Topic; Coronary Disease; Hemodynamics; Humans; Muscle, Smooth, Vascular; Niacinam

1996
Acute hemodynamic effects of nicorandil in coronary artery disease.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3

    Topics: Animals; Coronary Disease; Dogs; Hemodynamics; Humans; Niacinamide; Nicorandil; Vasodilator Agents

1992
Effects of nicorandil on coronary circulation and myocardial ischemia.
    The American journal of cardiology, 1989, Jun-20, Volume: 63, Issue:21

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Niacinamide; Nicorandil; Vasodilator Agents

1989

Trials

11 trials available for niacinamide and Coronary Heart Disease

ArticleYear
Nicorandil safety in the long-term treatment of coronary heart disease.
    Cardiovascular drugs and therapy, 1995, Volume: 9 Suppl 2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Blood Pressure;

1995
Effects of nicorandil on kinetics of oxygen uptake at the onset of exercise in patients with coronary artery disease.
    The American journal of cardiology, 1995, Sep-01, Volume: 76, Issue:7

    Topics: Adult; Aged; Coronary Disease; Cross-Over Studies; Double-Blind Method; Exercise; Exercise Test; Fem

1995
Coronary microvascular response to intracoronary administration of nicorandil.
    The American journal of cardiology, 1995, Feb-01, Volume: 75, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Coronary

1995
Dose-related haemodynamic effects and pharmacokinetics of oral nicorandil in patients evaluated for chest pain.
    International journal of cardiology, 1994, Volume: 44, Issue:3

    Topics: Analysis of Variance; Cardiac Catheterization; Chest Pain; Coronary Disease; Dose-Response Relations

1994
A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Diltiazem; Dose-Response Relationship

1993
A double-blind comparison of a beta-blocker and a potassium channel opener in exercise induced angina.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Aged; Angina Pectoris; Atenolol; Blood Pressure; Coronary Circulation; Coronary Disease; Double-Blin

1993
Effective and safe dose of intracoronary nicorandil in man.
    Japanese circulation journal, 1995, Volume: 59, Issue:11

    Topics: Aged; Coronary Angiography; Coronary Disease; Coronary Vessels; Dose-Response Relationship, Drug; Fe

1995
Effects of nicorandil, an antianginal potassium channel opener, on left ventricular systolic and diastolic function in patients with chronic coronary artery disease.
    The American journal of cardiology, 1997, Jun-15, Volume: 79, Issue:12

    Topics: Adult; Aged; Chronic Disease; Coronary Disease; Diastole; Female; Humans; Male; Middle Aged; Niacina

1997
Differential effects of N-acetylcysteine on nitroglycerin- and nicorandil-induced vasodilation in human coronary circulation.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:1

    Topics: Acetylcysteine; Coronary Circulation; Coronary Disease; Coronary Vessels; Female; Free Radical Scave

1998
Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind Method; Electrocardiogr

1992
Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3

    Topics: Adult; Aged; Blood Pressure; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Ex

1992

Other Studies

40 other studies available for niacinamide and Coronary Heart Disease

ArticleYear
[CLINICAL OBSERVATIONS AND THERAPEUTIC RESULTS IN SUBJECTS WITH ISCHEMIC CARDIOPATHY TREATED WITH AN ENZYME COMPLEX ASSOCIATED WITH A VASODILATOR DRUG].
    Gazzetta medica italiana, 1964, Volume: 123

    Topics: Adenosine Triphosphate; Coronary Disease; Drug Therapy; Electrocardiography; Flavin Mononucleotide;

1964
[ON THE CLINICAL VALUE OF COLLATERAL TROPHO-ENZYMATIC THERAPY IN ACUTE AND CHRONIC HEART DISEASES].
    Gazzetta medica italiana, 1964, Volume: 123

    Topics: Coenzymes; Coronary Disease; Heart Diseases; Humans; Hypertension; Khellin; Niacin; Niacinamide; Pul

1964
[Efficacy of nicorandil (SG-75), a substance with nitro-properties and long-term effects in coronary patients: improvement of LV-function and wall motility without pacing-induced myocardial ischemia].
    Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:11

    Topics: Aged; Angiography; Cardiac Pacing, Artificial; Coronary Disease; Heart Ventricles; Hemodynamics; Hum

1982
Nicorandil attenuates myocardial acidosis during coronary occlusion in dogs.
    British journal of pharmacology, 1984, Volume: 81, Issue:2

    Topics: Acidosis; Animals; Coronary Disease; Dogs; Female; Heart Diseases; Male; Niacinamide; Nicorandil; Va

1984
Effects of nicorandil, a new antianginal agent, and nifedipine on collateral blood flow in a chronic coronary occlusion model.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:2

    Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dog

1984
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiaze

1996
Nicorandil improves ischemic changes in epicardial ECG during short-term coronary occlusion by opening ATP-sensitive potassium channels in pigs.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:6

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Electroc

1997
Nicorandil and cardiovascular performance in patients with coronary artery disease.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3

    Topics: Administration, Sublingual; Coronary Circulation; Coronary Disease; Female; Hemodynamics; Humans; Is

1992
Suppression of sympathetic nervous system activity by nicorandil during exercise.
    General pharmacology, 1992, Volume: 23, Issue:3

    Topics: Adult; Aged; Coronary Disease; Depression, Chemical; Electroencephalography; Epinephrine; Exercise;

1992
Nicorandil improves postischemic contractile function independently of direct myocardial effects.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:5

    Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Disease; Cromakalim; Dogs; Heart Function Tests

1990
Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: Adenosine Triphosphate; Animals; Coronary Disease; Glyburide; Heart; Kinetics; Male; Myocardial Cont

1991
Cardioprotective effects of KRN2391 and nicorandil on ischemic dysfunction in perfused rat heart.
    European journal of pharmacology, 1991, Nov-05, Volume: 204, Issue:2

    Topics: Animals; Coronary Disease; Cytosol; Glyburide; Heart Rate; In Vitro Techniques; Male; Myocardium; Ni

1991
Angiographic response to a vasodilating drug, nicorandil, in patients with coronary artery disease.
    Japanese heart journal, 1990, Volume: 31, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Coronary Angiography; Coronary Disease; Coronary Vessels; F

1990
[Clinical electrophysiological effects of nicorandil on the conduction system in humans].
    Kokyu to junkan. Respiration & circulation, 1990, Volume: 38, Issue:7

    Topics: Coronary Disease; Electrophysiology; Female; Heart Conduction System; Heart Rate; Humans; Male; Midd

1990
[Effect of nicorandil on coronary circulation in ischemic region].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: Animals; Blood Viscosity; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Infusi

1990
Beneficial effects of nicorandil on cardiovascular hemodynamics and left ventricular function.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Angina Pectoris; Cardiac Catheterization; Cardiac Pacing, Artificial; Coronary Disease; Female; Hear

1987
Effects of nicorandil on coronary hemodynamics in ischemic heart disease: comparison with nitroglycerin, nifedipine, and propranolol.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Adult; Aged; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Hemodynamics; Human

1987
Effects of nicorandil on coronary circulation in patients with ischemic heart disease: comparison with nitroglycerin.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Coronary Circulation; Coronary Disease; Coronary Vasospasm; Female; Hemodynamics; Humans; Male; Midd

1987
Comparative effects of nicorandil, nitroglycerin, nicotinic acid, and SG-86 on the metabolic status and functional recovery of the ischemic-reperfused myocardium.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Fatty Acids, Nonesterified; Female; Glucose;

1987
Effects of nicorandil and other antianginal drugs on myocardial pH in the ischemic dog heart.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Acidosis; Animals; Coronary Disease; Diltiazem; Dogs; Hydrogen-Ion Concentration; In Vitro Technique

1987
Examination of the direct effects of nicorandil, verapamil, propranolol, and nitroglycerin on the hypoxic canine myocardium.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; In Vitro Techniques; Male; Myocardium; Niacin

1987
Reduction of size of myocardial infarction with nicorandil, a new antianginal drug, after coronary artery occlusion in dogs.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:5

    Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; Male; Myocardial Infarction; Niacinamide; Nic

1988
Effects of nicorandil and nipradilol on ischemic myocardium in perfused rat heart.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Heart; In V

1989
Acute hemodynamic effects of single-dose nicorandil in coronary artery disease.
    The American journal of cardiology, 1989, Jun-20, Volume: 63, Issue:21

    Topics: Administration, Oral; Administration, Sublingual; Adult; Coronary Disease; Female; Hemodynamics; Hum

1989
Effects of intravenous administration of nicorandil on cardiovascular hemodynamics and left ventricular function.
    The American journal of cardiology, 1989, Jun-20, Volume: 63, Issue:21

    Topics: Aged; Coronary Disease; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; My

1989
Coronary vasodilatory action after nicorandil: a quantitative angiographic study.
    The American journal of cardiology, 1989, Jun-20, Volume: 63, Issue:21

    Topics: Administration, Sublingual; Adult; Aged; Angiography; Coronary Angiography; Coronary Disease; Corona

1989
Assessment of the antiarrhythmic activity of nicorandil during myocardial ischemia and reperfusion.
    European journal of pharmacology, 1989, Apr-12, Volume: 163, Issue:1

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Disease; Ele

1989
Protective effect of nicorandil on postischemic function and tissue adenine nucleotides following a brief period of low-flow global ischemia in the isolated perfused rat heart.
    Pharmacology, 1989, Volume: 38, Issue:4

    Topics: Adenine Nucleotides; Animals; Coronary Disease; Epoprostenol; Heart; Heart Function Tests; In Vitro

1989
Nicorandil and cardiovascular performance in anaesthetized pigs with a concentric coronary artery stenosis.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:6 Pt 2

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Conduction System; Heart Function

1989
Protection of acute ischemic myocardial injury by pharmacological intervention.
    Japanese circulation journal, 1989, Volume: 53, Issue:9

    Topics: Adenosine Triphosphatases; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium-Transporting ATPa

1989
[Effect of nicotinamide on neurohumoral regulation and lipid peroxidation in ischemic heart disease].
    Sovetskaia meditsina, 1988, Issue:1

    Topics: Adult; Antioxidants; Coronary Disease; Cyclic AMP; Cyclic GMP; Humans; Lipid Peroxides; Male; Middle

1988
Recovery of contractile function in post-ischaemic reperfused myocardium of conscious dogs: influence of nicorandil, a new antianginal agent.
    Cardiovascular research, 1986, Volume: 20, Issue:8

    Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Female; Heart; Heart Rate; Male; Myocardial Contrac

1986
Salutary action of nicorandil, a new antianginal drug, on myocardial metabolism during ischemia and on postischemic function in a canine preparation of brief, repetitive coronary artery occlusions: comparison with isosorbide dinitrate.
    Circulation, 1987, Volume: 76, Issue:4

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs;

1987
Coronary vasodilatory action after a single dose of nicorandil.
    The American journal of cardiology, 1988, Feb-01, Volume: 61, Issue:4

    Topics: Adult; Aged; Blood Pressure; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary

1988
Experimental studies on ischemic injury and reperfusion injury to the cardiac sarcoplasmic reticulum--the myocardial protective effect of nicorandil.
    Japanese circulation journal, 1988, Volume: 52, Issue:6

    Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Cardioplegic Solutions; Cardiopulmonary Bypass; Co

1988
Effectiveness of nicorandil in the preservation of myocardium stressed by transient ischemia and its influence on cardiac metabolism during coronary artery occlusion with subsequent reperfusion: a comparison with isosorbide dinitrate.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4

    Topics: Animals; Coronary Disease; Coronary Vessels; Dogs; Fatty Acids, Nonesterified; Glucose; Heart; Hemod

1985
Thyroid function and coronary atherosclerosis.
    Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:6

    Topics: Adult; Aged; Arteriosclerosis; Ascorbic Acid; Calcium; Cholesterol; Coronary Disease; Electrocardiog

1968
[On the comparative results of the use of Clarisco in peripheral vascular diseases].
    Minerva medica, 1970, Dec-05, Issue:97 Suppl

    Topics: Aged; Arteriosclerosis Obliterans; Choline; Coronary Disease; Folic Acid; Gangrene; Heparin; Humans;

1970
[Anti-hyperlipemic therapy in the secondary prevention of coronary heart disease. Long-term study].
    Bollettino della Societa italiana di cardiologia, 1974, Volume: 19, Issue:6

    Topics: Clofibrate; Coronary Disease; Female; Humans; Hyperlipidemias; Male; Niacinamide; Nicotinic Acids; P

1974
[Phosphorus compounds and their metabolites in ischemic heart diseases].
    Kardiologiia, 1974, Volume: 14, Issue:8

    Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Tripho

1974