Page last updated: 2024-10-19

niacinamide and Chronic Primary Open Angle Glaucoma

niacinamide has been researched along with Chronic Primary Open Angle Glaucoma in 6 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Of these, 42 patients with treated open-angle glaucoma and moderate visual field loss in at least 1 eye were selected for inclusion and randomized."1.72Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial. ( Blumberg, DM; Cioffi, GA; De Moraes, CG; John, SWM; Liebmann, JM; Williams, PA, 2022)
" The quantitative dosage also disclosed a significantly lower plasma nicotinamide concentration (-33%; P = 0."1.51Nicotinamide Deficiency in Primary Open-Angle Glaucoma. ( Allouche, S; Amati-Bonneau, P; Bocca, C; Bonneau, D; Chao de la Barca, JM; Coulbault, L; Gohier, P; Guehlouz, K; Kouassi Nzoughet, J; Lenaers, G; Leruez, S; Milea, D; Muller, J; Procaccio, V; Reynier, P; Simard, G, 2019)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's5 (83.33)2.80

Authors

AuthorsStudies
De Moraes, CG2
John, SWM1
Williams, PA2
Blumberg, DM1
Cioffi, GA1
Liebmann, JM2
Leung, CKS1
Ren, ST1
Chan, PPM1
Wan, KHN1
Kam, AKW1
Lai, GWK1
Chiu, VSM1
Ko, MWL1
Yiu, CKF1
Yu, MCY1
Quah Qin Xian, N1
Wong, FYK1
Hui, F1
Tang, J1
McGuinness, MB1
Hadoux, X1
Casson, RJ1
Coote, M1
Trounce, IA1
Martin, KR1
van Wijngaarden, P1
Crowston, JG1
Kouassi Nzoughet, J1
Chao de la Barca, JM1
Guehlouz, K1
Leruez, S1
Coulbault, L1
Allouche, S1
Bocca, C1
Muller, J1
Amati-Bonneau, P1
Gohier, P1
Bonneau, D1
Simard, G1
Milea, D1
Lenaers, G1
Procaccio, V1
Reynier, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study[NCT05695027]Phase 2/Phase 3188 participants (Anticipated)Interventional2023-03-14Recruiting
Nutritional Supplements and Performance During Visual Field Testing[NCT03797469]32 participants (Actual)Interventional2019-04-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for niacinamide and Chronic Primary Open Angle Glaucoma

ArticleYear
Nicotinamide riboside as a neuroprotective therapy for glaucoma: study protocol for a randomized, double-blind, placebo-control trial.
    Trials, 2022, Jan-17, Volume: 23, Issue:1

    Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Multicenter Studies as Topic; Nerve Fibers; Neuroprotection;

2022
Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.
    Clinical & experimental ophthalmology, 2020, Volume: 48, Issue:7

    Topics: Dietary Supplements; Electroretinography; Glaucoma; Glaucoma, Open-Angle; Humans; Niacinamide; Photi

2020

Other Studies

4 other studies available for niacinamide and Chronic Primary Open Angle Glaucoma

ArticleYear
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
    JAMA ophthalmology, 2022, Jan-01, Volume: 140, Issue:1

    Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure;

2022
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
    JAMA ophthalmology, 2022, Jan-01, Volume: 140, Issue:1

    Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure;

2022
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
    JAMA ophthalmology, 2022, Jan-01, Volume: 140, Issue:1

    Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure;

2022
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
    JAMA ophthalmology, 2022, Jan-01, Volume: 140, Issue:1

    Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure;

2022
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma-Reply.
    JAMA ophthalmology, 2022, 04-01, Volume: 140, Issue:4

    Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid

2022
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma.
    JAMA ophthalmology, 2022, 04-01, Volume: 140, Issue:4

    Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid

2022
Nicotinamide Deficiency in Primary Open-Angle Glaucoma.
    Investigative ophthalmology & visual science, 2019, 06-03, Volume: 60, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, Liquid; Cohort Studies; Female

2019