Page last updated: 2024-10-19

niacinamide and Chronic Hepatitis B

niacinamide has been researched along with Chronic Hepatitis B in 14 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Hepatotoxicity induced by sorafenib and antiviral therapy is a limitation for its continuation treatment for patients with advanced hepatitis B virus-related hepatocellular carcinoma (HCC)."9.20Prospective analysis of tiopronin in prevention of sorafenib and antiviral therapy inducing liver toxicity in advanced hepatitis B virus-related hepatocellular carcinoma. ( Guo, W; Li, J; Qiu, X; Yan, B; Zhang, S, 2015)
"The Sorafenib Hepatocellular Carcinoma (HCC) Assessment Randomized Protocol (SHARP) trial demonstrated that sorafenib improves overall survival and is safe for patients with advanced HCC."9.16Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial. ( Beaugrand, M; Bolondi, L; Bruix, J; Craxi, A; Galle, PR; Gerken, G; Llovet, JM; Marrero, JA; Mazzaferro, V; Moscovici, M; Nadel, A; Porta, C; Raoul, JL; Sangiovanni, A; Santoro, A; Shan, M; Sherman, M; Voliotis, D, 2012)
"Sorafenib is recommended as the treatment of choice for hepatocellular carcinoma (HCC) with extrahepatic spread (EHS)."7.81Sorafenib therapy for hepatocellular carcinoma with extrahepatic spread: treatment outcome and prognostic factors. ( Ahn, JM; Cho, JY; Choi, MS; Gwak, GY; Koh, KC; Lee, JH; Lim, HY; Paik, SW; Paik, YH; Sinn, DH; Sohn, W; Yoo, BC, 2015)
"Sorafenib is currently the sole molecular targeted agent that improves overall survival in advanced hepatocellular carcinoma (HCC)."7.81Long-term outcomes of patients with advanced hepatocellular carcinoma who achieved complete remission after sorafenib therapy. ( Park, JG, 2015)
"Sorafenib, a multitargeted tyrosine kinase inhibitor, is now the treatment of choice for systemic therapy of patients with advanced hepatocellular carcinoma (HCC)."7.77Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective comparison with previously known prognostic models. ( Baek, KK; Kang, WK; Kim, JH; Lee, J; Lim, HY; Park, JO; Park, SH; Park, YS; Uhm, JE, 2011)
"Hepatotoxicity induced by sorafenib and antiviral therapy is a limitation for its continuation treatment for patients with advanced hepatitis B virus-related hepatocellular carcinoma (HCC)."5.20Prospective analysis of tiopronin in prevention of sorafenib and antiviral therapy inducing liver toxicity in advanced hepatitis B virus-related hepatocellular carcinoma. ( Guo, W; Li, J; Qiu, X; Yan, B; Zhang, S, 2015)
"The Sorafenib Hepatocellular Carcinoma (HCC) Assessment Randomized Protocol (SHARP) trial demonstrated that sorafenib improves overall survival and is safe for patients with advanced HCC."5.16Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial. ( Beaugrand, M; Bolondi, L; Bruix, J; Craxi, A; Galle, PR; Gerken, G; Llovet, JM; Marrero, JA; Mazzaferro, V; Moscovici, M; Nadel, A; Porta, C; Raoul, JL; Sangiovanni, A; Santoro, A; Shan, M; Sherman, M; Voliotis, D, 2012)
"Sorafenib is recommended as the treatment of choice for hepatocellular carcinoma (HCC) with extrahepatic spread (EHS)."3.81Sorafenib therapy for hepatocellular carcinoma with extrahepatic spread: treatment outcome and prognostic factors. ( Ahn, JM; Cho, JY; Choi, MS; Gwak, GY; Koh, KC; Lee, JH; Lim, HY; Paik, SW; Paik, YH; Sinn, DH; Sohn, W; Yoo, BC, 2015)
"Sorafenib is currently the sole molecular targeted agent that improves overall survival in advanced hepatocellular carcinoma (HCC)."3.81Long-term outcomes of patients with advanced hepatocellular carcinoma who achieved complete remission after sorafenib therapy. ( Park, JG, 2015)
"Sorafenib, a multitargeted tyrosine kinase inhibitor, is now the treatment of choice for systemic therapy of patients with advanced hepatocellular carcinoma (HCC)."3.77Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective comparison with previously known prognostic models. ( Baek, KK; Kang, WK; Kim, JH; Lee, J; Lim, HY; Park, JO; Park, SH; Park, YS; Uhm, JE, 2011)
"Hepatocellular carcinoma is the leading cause of death in cirrhosis."2.46Review article: the management of hepatocellular carcinoma. ( Cabrera, R; Nelson, DR, 2010)
"The occurrence of hepatocellular carcinoma is about 3-15 % in patients with alcoholic liver disease."2.46[Hepatocellular carcinoma: occurrence, risk factors, biomarkers]. ( Fehér, J; Lengyel, G, 2010)
"Mean survival in hepatocellular carcinoma remains low."1.42Multidisciplinary Approach in Hepatocellular Carcinoma in a Level II Hospital: The First Decade of Hospital Universitario Fundacion Alcorcon. ( Alonso López, S; Burgos, Rde L; Fernandez Cebrián, JM; Fernández Rodríguez, C; Gutiérrez Garcia, ML; LIedó Navarro, JL; Loinaz Segurola, C; Martel Villagrán, J; Martín Ríos, D; Ochando Cerdán, F, 2015)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's13 (92.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sohn, W1
Paik, YH1
Cho, JY1
Lim, HY2
Ahn, JM1
Sinn, DH1
Gwak, GY1
Choi, MS1
Lee, JH1
Koh, KC1
Paik, SW1
Yoo, BC1
Yang, Y1
Wen, F1
Li, J2
Zhang, P1
Yan, W1
Hao, P1
Xia, F1
Bi, F1
Li, Q1
Qiu, X1
Guo, W1
Yan, B1
Zhang, S1
Park, JG1
Loinaz Segurola, C1
LIedó Navarro, JL1
Burgos, Rde L1
Martín Ríos, D1
Ochando Cerdán, F1
Alonso López, S1
Martel Villagrán, J1
Gutiérrez Garcia, ML1
Fernandez Cebrián, JM1
Fernández Rodríguez, C1
Dika, IE1
Harding, JJ1
Abou-Alfa, GK1
Cabrera, R1
Nelson, DR1
Yeganeh, M1
Finn, RS1
Saab, S1
Fehér, J1
Lengyel, G1
Iavarone, M1
Perrino, M1
Viganò, M1
Beck-Peccoz, P1
Fugazzola, L1
Villanueva, A1
Newell, P1
Hoshida, Y1
Baek, KK1
Kim, JH1
Uhm, JE1
Park, SH1
Lee, J1
Park, JO1
Park, YS1
Kang, WK1
Nguyen, V1
George, J1
van der Poorten, D1
Bruix, J1
Raoul, JL1
Sherman, M1
Mazzaferro, V1
Bolondi, L1
Craxi, A1
Galle, PR1
Santoro, A1
Beaugrand, M1
Sangiovanni, A1
Porta, C1
Gerken, G1
Marrero, JA1
Nadel, A1
Shan, M1
Moscovici, M1
Voliotis, D1
Llovet, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Cohort Study of Single Agent Memantine in Patients With Child-Pugh Score ≥ B7 Cirrhosis and Hepatocellular Carcinoma[NCT06007846]Phase 2/Phase 312 participants (Anticipated)Interventional2023-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for niacinamide and Chronic Hepatitis B

ArticleYear
Hepatocellular carcinoma in patients with HIV.
    Current opinion in HIV and AIDS, 2017, Volume: 12, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Coinfection; Hepatitis B, Chronic; Hepatitis C, Ch

2017
Review article: the management of hepatocellular carcinoma.
    Alimentary pharmacology & therapeutics, 2010, Feb-15, Volume: 31, Issue:4

    Topics: Ablation Techniques; Adult; Antineoplastic Agents; Asian People; Benzenesulfonates; Biopsy; Black Pe

2010
[Hepatocellular carcinoma: occurrence, risk factors, biomarkers].
    Orvosi hetilap, 2010, Jun-06, Volume: 151, Issue:23

    Topics: Antineoplastic Agents; Benzenesulfonates; Biomarkers, Tumor; Carcinoma, Hepatocellular; Copper; Deve

2010
Inherited hepatocellular carcinoma.
    Best practice & research. Clinical gastroenterology, 2010, Volume: 24, Issue:5

    Topics: Algorithms; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Catheter Ablation;

2010

Trials

2 trials available for niacinamide and Chronic Hepatitis B

ArticleYear
Prospective analysis of tiopronin in prevention of sorafenib and antiviral therapy inducing liver toxicity in advanced hepatitis B virus-related hepatocellular carcinoma.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:10

    Topics: Antineoplastic Agents; Antiviral Agents; Carcinoma, Hepatocellular; Drug Therapy, Combination; Femal

2015
Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial.
    Journal of hepatology, 2012, Volume: 57, Issue:4

    Topics: Aged; Alcoholism; Antineoplastic Agents; Carcinoma, Hepatocellular; Diarrhea; Disease Progression; F

2012

Other Studies

8 other studies available for niacinamide and Chronic Hepatitis B

ArticleYear
Sorafenib therapy for hepatocellular carcinoma with extrahepatic spread: treatment outcome and prognostic factors.
    Journal of hepatology, 2015, Volume: 62, Issue:5

    Topics: Aged; Antineoplastic Agents; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Femal

2015
A high baseline HBV load and antiviral therapy affect the survival of patients with advanced HBV-related HCC treated with sorafenib.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:9

    Topics: Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Female; Hepatectomy; Hepatitis

2015
Long-term outcomes of patients with advanced hepatocellular carcinoma who achieved complete remission after sorafenib therapy.
    Clinical and molecular hepatology, 2015, Volume: 21, Issue:3

    Topics: Adult; Aged; alpha-Fetoproteins; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular

2015
Multidisciplinary Approach in Hepatocellular Carcinoma in a Level II Hospital: The First Decade of Hospital Universitario Fundacion Alcorcon.
    Hepato-gastroenterology, 2015, Volume: 62, Issue:140

    Topics: Ablation Techniques; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Catheter Ablation; Chem

2015
Apparent remission of a solitary metastatic pulmonary lesion in a liver transplant recipient treated with sorafenib.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2009, Volume: 9, Issue:12

    Topics: Benzenesulfonates; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Combined Modality Therapy; Hep

2009
Sorafenib-induced destructive thyroiditis.
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:9

    Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Chronic Disease; Hepatitis B, C

2010
Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective comparison with previously known prognostic models.
    Oncology, 2011, Volume: 80, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular;

2011
A maxillary mass in a HBV-cirrhotic patient.
    Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:6

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Biomarkers, Tumor; Biopsy; Carcinoma, Hepatocellular

2012