niacinamide has been researched along with Cerebral Infarction in 11 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results provide, to our knowledge, the first evidence that nicaraven is effective against ischemia-reperfusion injury in the brain and demonstrate that oxygen free radicals generated during reperfusion are important triggers of ischemic brain damage." | 7.69 | Attenuation of ischemia-reperfusion injury in the rat neocortex by the hydroxyl radical scavenger nicaraven. ( Kassell, NF; Lee, KS; Toyoda, T, 1997) |
| "The effect of a single oral dose of nicorandil (N-2-(hydroxyethyl)-nicotinamide nitrate, CAS 65141-46-0) on the regional cerebral blood flow (rCBF) was studied in 9 patients with cerebral infarction." | 7.68 | Effects of nicorandil on regional cerebral blood flow in patients with chronic cerebral infarction. Preliminary communication. ( Bokura, K; Kobayashi, S; Murao, M; Okada, K; Suyama, N; Yamaguchi, S, 1992) |
| " The results provide, to our knowledge, the first evidence that nicaraven is effective against ischemia-reperfusion injury in the brain and demonstrate that oxygen free radicals generated during reperfusion are important triggers of ischemic brain damage." | 3.69 | Attenuation of ischemia-reperfusion injury in the rat neocortex by the hydroxyl radical scavenger nicaraven. ( Kassell, NF; Lee, KS; Toyoda, T, 1997) |
| "The effect of a single oral dose of nicorandil (N-2-(hydroxyethyl)-nicotinamide nitrate, CAS 65141-46-0) on the regional cerebral blood flow (rCBF) was studied in 9 patients with cerebral infarction." | 3.68 | Effects of nicorandil on regional cerebral blood flow in patients with chronic cerebral infarction. Preliminary communication. ( Bokura, K; Kobayashi, S; Murao, M; Okada, K; Suyama, N; Yamaguchi, S, 1992) |
| " Patients in the first group (experimental group), consisting of 32 patients, as part of combined therapy received ascorbic acid (5% solution twice a day in a recommended dosage of 20 ml/day for 20 days); the second group (37 patients) received 10 ml of cytoflavin intravenously by drop infusion twice a day for 10 days; the third group received cytoflavin for 20 days (from day 1 to day 10 - 20 ml a day, from day 11 to day 20 - 10 ml a day)." | 2.80 | [Performance evaluation of integrated cytoprotective therapy of different duration in patients with cerebral infarction]. ( Chichanovskaia, LV; Eliseev, EV; Kabaeva, EN; Kovalenko, AL; Lukin, DI; Nazarov, MV; Nedorostkova, TIu; Rumiantseva, SA; Silina, EV; Stupin, VA; Tsukurova, LA, 2015) |
| " In addition to basic therapy, 16 patients of the main group were treated with the antioxidant power-normalizing drug cytoflavin used in dosage 20 ml/day intravenous in drops from the 1st to 10th day and 2 tablets twice a day from the 11th to 35th day." | 2.75 | [Effect of early correction of energy and free-radical homeostasis on the clinical-morphological presentation of cerebral infarction]. ( Bolevich, SB; Fedin, AI; Goluzova, IuN; Iliukhina, OA; Men'shova, NI; Rumiantseva, SA; Silina, EV; Vasil'ev, IuD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chichanovskaia, LV | 1 |
| Tsukurova, LA | 1 |
| Kovalenko, AL | 1 |
| Nazarov, MV | 1 |
| Lukin, DI | 1 |
| Rumiantseva, SA | 2 |
| Silina, EV | 2 |
| Stupin, VA | 1 |
| Nedorostkova, TIu | 1 |
| Kabaeva, EN | 1 |
| Eliseev, EV | 1 |
| Fedin, AI | 1 |
| Bolevich, SB | 1 |
| Vasil'ev, IuD | 1 |
| Men'shova, NI | 1 |
| Iliukhina, OA | 1 |
| Goluzova, IuN | 1 |
| Sung, JH | 1 |
| Kim, MO | 1 |
| Koh, PO | 1 |
| Toyoda, T | 1 |
| Kassell, NF | 1 |
| Lee, KS | 1 |
| Ayoub, IA | 5 |
| Lee, EJ | 2 |
| Ogilvy, CS | 3 |
| Beal, MF | 1 |
| Maynard, KI | 5 |
| Mokudai, T | 1 |
| Sakakibara, Y | 2 |
| Shen, CC | 1 |
| Mitha, AP | 1 |
| Chang, ML | 1 |
| Yang, J | 1 |
| Kem, S | 1 |
| Klaidman, L | 1 |
| Sugawara, T | 1 |
| Chan, PH | 1 |
| Adams, JD | 1 |
| Kobayashi, S | 1 |
| Yamaguchi, S | 1 |
| Okada, K | 1 |
| Suyama, N | 1 |
| Bokura, K | 1 |
| Murao, M | 1 |
2 trials available for niacinamide and Cerebral Infarction
| Article | Year |
|---|---|
[Performance evaluation of integrated cytoprotective therapy of different duration in patients with cerebral infarction].
Topics: Aged; Antioxidants; Ascorbic Acid; Cerebral Infarction; Cognition; Drug Administration Schedule; Dru | 2015 |
[Effect of early correction of energy and free-radical homeostasis on the clinical-morphological presentation of cerebral infarction].
Topics: Adult; Aged; Antioxidants; Biomarkers; Cerebral Infarction; Drug Combinations; Energy Metabolism; Fe | 2010 |
9 other studies available for niacinamide and Cerebral Infarction
| Article | Year |
|---|---|
Nicotinamide prevents the down-regulation of MEK/ERK/p90RSK signaling cascade in brain ischemic injury.
Topics: Animals; Brain Injuries; Brain Ischemia; Cerebral Infarction; Down-Regulation; Extracellular Signal- | 2012 |
Attenuation of ischemia-reperfusion injury in the rat neocortex by the hydroxyl radical scavenger nicaraven.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Free Radical Scavengers; Hydroxyl Rad | 1997 |
Nicotinamide reduces infarction up to two hours after the onset of permanent focal cerebral ischemia in Wistar rats.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Dose-Response Relationship, Drug; Male; Niacinamide; R | 1999 |
Delayed treatment with nicotinamide (Vitamin B(3)) improves neurological outcome and reduces infarct volume after transient focal cerebral ischemia in Wistar rats.
Topics: Animals; Brain; Cerebral Infarction; Energy Metabolism; Ischemic Attack, Transient; Male; Motor Acti | 2000 |
Delayed multidose treatment with nicotinamide extends the degree and duration of neuroprotection by reducing infarction and improving behavioral scores up to two weeks following transient focal cerebral ischemia in Wistar rats.
Topics: Animals; Cerebral Infarction; Ischemic Attack, Transient; Male; Motor Activity; Neuroprotective Agen | 2001 |
Therapeutic window for nicotinamide following transient focal cerebral ischemia.
Topics: Animals; Behavior, Animal; Cerebral Infarction; Drug Administration Schedule; Ischemic Attack, Trans | 2002 |
Delayed treatment with nicotinamide (vitamin B3) reduces the infarct volume following focal cerebral ischemia in spontaneously hypertensive rats, diabetic and non-diabetic Fischer 344 rats.
Topics: Animals; Blood Gas Analysis; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Diabe | 2002 |
Nicotinamide and ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Cerebral Infarction; DNA Fragmentation; Excitatory Amino Acid Antagonists; | 2002 |
Effects of nicorandil on regional cerebral blood flow in patients with chronic cerebral infarction. Preliminary communication.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Cerebral Infarction; Cerebrovascular | 1992 |