Page last updated: 2024-10-19

niacinamide and Cardiovascular Stroke

niacinamide has been researched along with Cardiovascular Stroke in 47 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Salutary effect of nicorandil, a K+ adenosine triphosphate channel opener, on restoration of myocardial blood flow and functional improvement after coronary revascularization was investigated in 20 patients with first anterior acute myocardial infarction."9.08Salutary effect of adjunctive intracoronary nicorandil administration on restoration of myocardial blood flow and functional improvement in patients with acute myocardial infarction. ( Hirayama, A; Hori, M; Ishikura, F; Kitakaze, M; Kodama, K; Komamura, K; Lim, YJ; Masuyama, T; Sakata, Y, 1997)
"This study was designed to assess the cardioprotective effect of intravenous nicorandil, a potassium channel opener, in preventing reperfusion injury in acute myocardial infarction."9.08Cardioprotective effect of intravenous nicorandil in patients with successful reperfusion for acute myocardial infarction. ( Daikoku, S; Goto, Y; Haze, K; Itoh, A; Kobayashi, Y; Miyazaki, S; Nonogi, H; Ohshima, S, 1998)
"Mice treated with sorafenib or vehicle for 3 weeks underwent induced myocardial infarction (MI) after 1 week of treatment."7.80Sorafenib cardiotoxicity increases mortality after myocardial infarction. ( Barbe, M; Berretta, RM; Dunn, J; Duran, JM; Force, T; Gao, E; Gross, P; Houser, SR; Husain, S; Kubo, H; Lal, H; Makarewich, CA; Sharp, TE; Starosta, T; Trappanese, D; Vagnozzi, RJ; Yu, D, 2014)
"Adjunctive intracoronary administration of nicorandil, an ATP-sensitive potassium channel opener, after successful coronary revascularization was performed in a 54-year-old patient with acute myocardial infarction."7.69Disappearance of the 'no-reflow' phenomenon after adjunctive intracoronary administration of nicorandil in a patient with acute myocardial infarction. ( Hasegawa, S; Hirayama, A; Ishikura, F; Kodama, K; Komamura, K; Sakata, Y, 1997)
"Hemodynamic effects of nicorandil on exercise-induced impairment of left ventricular function were studied in nine patients with old myocardial infarction but without angina pectoris."7.67Effects of a new vasodilator, nicorandil, on exercise-induced impairment of left ventricular function in patients with old myocardial infarction. ( Horisawa, T; Iwase, M; Kamihara, S; Koide, M; Miyahara, T; Noda, S; Tsunekawa, A; Tsuzuki, M; Yokota, M; Yoshida, J, 1987)
"The effects of nicorandil, a new antianginal drug, on size of myocardial infarction were studied in anesthetized, open-chest dogs after left anterior descending coronary artery occlusion."7.67Reduction of size of myocardial infarction with nicorandil, a new antianginal drug, after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1988)
"Treatment with sorafenib prolongs progression-free survival in patients with advanced clear-cell renal cell carcinoma."5.42[Three Patients with Acute Myocardial Infarction Associated with Targeted Therapy of Sorafenib for Metastatic Renal Cell Carcinoma : Case Report]. ( Deguchi, T; Horie, K; Kato, T; Kawata, K; Kikuchi, M; Miyazaki, T; Mizutani, K; Nakano, M; Seike, K; Takagi, K; Takai, M; Tsuchiya, T; Ushikoshi, H; Yasuda, M; Yokoi, S, 2015)
"Heart failure was produced by myocardial infarction, and was associated with markedly increased AMPK and SIRT1 protein levels."5.40Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure. ( Gu, XS; Lei, JP; Li, L; Su, DF; Wang, ZB; Ye, Z; Zheng, X, 2014)
"Sorafenib is a multikinase inhibitor that targets signaling pathways necessary for cellular proliferation and survival."5.35Sorafenib-induced acute myocardial infarction due to coronary artery spasm. ( Arima, Y; Fukushima, H; Nakamura, S; Noda, K; Ogawa, H; Oshima, S; Shono, M; Taniguchi, I, 2009)
"Salutary effect of nicorandil, a K+ adenosine triphosphate channel opener, on restoration of myocardial blood flow and functional improvement after coronary revascularization was investigated in 20 patients with first anterior acute myocardial infarction."5.08Salutary effect of adjunctive intracoronary nicorandil administration on restoration of myocardial blood flow and functional improvement in patients with acute myocardial infarction. ( Hirayama, A; Hori, M; Ishikura, F; Kitakaze, M; Kodama, K; Komamura, K; Lim, YJ; Masuyama, T; Sakata, Y, 1997)
"This study was designed to assess the cardioprotective effect of intravenous nicorandil, a potassium channel opener, in preventing reperfusion injury in acute myocardial infarction."5.08Cardioprotective effect of intravenous nicorandil in patients with successful reperfusion for acute myocardial infarction. ( Daikoku, S; Goto, Y; Haze, K; Itoh, A; Kobayashi, Y; Miyazaki, S; Nonogi, H; Ohshima, S, 1998)
"Mice treated with sorafenib or vehicle for 3 weeks underwent induced myocardial infarction (MI) after 1 week of treatment."3.80Sorafenib cardiotoxicity increases mortality after myocardial infarction. ( Barbe, M; Berretta, RM; Dunn, J; Duran, JM; Force, T; Gao, E; Gross, P; Houser, SR; Husain, S; Kubo, H; Lal, H; Makarewich, CA; Sharp, TE; Starosta, T; Trappanese, D; Vagnozzi, RJ; Yu, D, 2014)
"Adjunctive intracoronary administration of nicorandil, an ATP-sensitive potassium channel opener, after successful coronary revascularization was performed in a 54-year-old patient with acute myocardial infarction."3.69Disappearance of the 'no-reflow' phenomenon after adjunctive intracoronary administration of nicorandil in a patient with acute myocardial infarction. ( Hasegawa, S; Hirayama, A; Ishikura, F; Kodama, K; Komamura, K; Sakata, Y, 1997)
"Hemodynamic effects of nicorandil on exercise-induced impairment of left ventricular function were studied in nine patients with old myocardial infarction but without angina pectoris."3.67Effects of a new vasodilator, nicorandil, on exercise-induced impairment of left ventricular function in patients with old myocardial infarction. ( Horisawa, T; Iwase, M; Kamihara, S; Koide, M; Miyahara, T; Noda, S; Tsunekawa, A; Tsuzuki, M; Yokota, M; Yoshida, J, 1987)
"The effects of nicorandil, a new antianginal drug, on size of myocardial infarction were studied in anesthetized, open-chest dogs after left anterior descending coronary artery occlusion."3.67Reduction of size of myocardial infarction with nicorandil, a new antianginal drug, after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1988)
"Nicorandil and diltiazem were both found to decrease the frequency of anginal attacks and the consumption of nitroglycerin tablets (P < 0."2.67A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris. ( Blin, P; Guermonprez, JL; Peterlongo, F, 1993)
"Treatment with sorafenib prolongs progression-free survival in patients with advanced clear-cell renal cell carcinoma."1.42[Three Patients with Acute Myocardial Infarction Associated with Targeted Therapy of Sorafenib for Metastatic Renal Cell Carcinoma : Case Report]. ( Deguchi, T; Horie, K; Kato, T; Kawata, K; Kikuchi, M; Miyazaki, T; Mizutani, K; Nakano, M; Seike, K; Takagi, K; Takai, M; Tsuchiya, T; Ushikoshi, H; Yasuda, M; Yokoi, S, 2015)
"Heart failure was produced by myocardial infarction, and was associated with markedly increased AMPK and SIRT1 protein levels."1.40Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure. ( Gu, XS; Lei, JP; Li, L; Su, DF; Wang, ZB; Ye, Z; Zheng, X, 2014)
"Sorafenib is a multikinase inhibitor that targets signaling pathways necessary for cellular proliferation and survival."1.35Sorafenib-induced acute myocardial infarction due to coronary artery spasm. ( Arima, Y; Fukushima, H; Nakamura, S; Noda, K; Ogawa, H; Oshima, S; Shono, M; Taniguchi, I, 2009)
"Late treatment with nicorandil had no effect on infarct size (43."1.30Myocardial protection afforded by nicorandil and ischaemic preconditioning in a rabbit infarct model in vivo. ( Baxter, GF; Imagawa, J; Yellon, DM, 1998)
"Pretreatment with nicorandil and glyceryl trinitrate caused a marked reduction in myocardial infarct size expressed as percent of the area at risk [NC/pre group, 7."1.29Effects of nicorandil and glyceryl trinitrate on infarct size, adenosine release, and neutrophil infiltration in the dog. ( Gross, GJ; Mizumura, T; Nithipatikom, K, 1995)
" Adverse events usually occurred early in the course of treatment."1.29Safety profile of an anti-anginal agent with potassium channel opening activity: an overview. ( Roland, E, 1993)
"Nicorandil is a compound with hybrid properties of nitrates and adenosine triphosphate (ATP)-sensitive potassium channel (KATP) opening."1.29Limitation of myocardial infarct size by nicorandil after sustained ischemia in pigs. ( Branzi, A; Galiè, N; Guarnieri, C; Magnani, B; Parlangeli, R; Traini, AM; Ussia, GP; Vaona, I; Zimarino, M, 1995)
"To study the effects of stepwise early treatment in variant angina pectoris, frequencies of cardiac events and complications were examined after three different types of treatment."1.28A new strategy for the reduction of acute myocardial infarction in variant angina. ( Fukuma, N; Hata, N; Hayakawa, H; Kishida, H; Saito, T; Tada, Y; Tetsuoh, Y; Yamazaki, Y; Yasutake, M, 1991)
"The myocardial infarction was shown to result in shifts of the smooth muscle contractile function which were similar to those in EPS, though being somewhat less pronounced."1.27[Disorders of contractile function and adrenoreactivity of the portal vein in emotionally-painful stress and experimental myocardial infarct and their prevention by means of membrane protectors]. ( Dosmagambetova, RS; Manukhina, EB; Meerson, FZ, 1984)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199011 (23.40)18.7374
1990's24 (51.06)18.2507
2000's3 (6.38)29.6817
2010's9 (19.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eltze, T1
Boer, R1
Wagner, T1
Weinbrenner, S1
McDonald, MC1
Thiemermann, C2
Bürkle, A1
Klein, T1
Zabielska, MA1
Adamus, J1
Kowalski, R1
Gebicki, J1
Slominska, EM1
Khalpey, Z1
Smolenski, RT1
Pereverzev, DI1
Simonova, NV1
Dorovskikh, VA1
Anokhina, RA1
Lv, YX1
Zhong, S1
Tang, H1
Luo, B1
Chen, SJ1
Chen, L1
Zheng, F1
Zhang, L1
Wang, L2
Li, XY1
Yan, YW1
Pan, YM1
Jiang, M1
Zhang, YE1
Yang, JY1
Guo, LY1
Chen, SY1
Wang, JN1
Tang, JM1
Gu, XS1
Wang, ZB1
Ye, Z1
Lei, JP1
Li, L1
Su, DF1
Zheng, X1
Duran, JM1
Makarewich, CA1
Trappanese, D1
Gross, P1
Husain, S1
Dunn, J1
Lal, H1
Sharp, TE1
Starosta, T1
Vagnozzi, RJ1
Berretta, RM1
Barbe, M1
Yu, D1
Gao, E1
Kubo, H1
Force, T1
Houser, SR1
Cheng, W1
Wu, P1
Du, Y1
Wang, Y1
Zhou, N1
Ge, Y1
Yang, Z1
Takagi, K1
Takai, M1
Kawata, K1
Horie, K1
Kikuchi, M1
Kato, T1
Mizutani, K1
Seike, K1
Tsuchiya, T1
Yasuda, M1
Yokoi, S1
Nakano, M1
Ushikoshi, H1
Miyazaki, T1
Deguchi, T1
Giribabu, N1
Roslan, J1
Rekha, SS1
Salleh, N1
Arima, Y1
Oshima, S1
Noda, K1
Fukushima, H1
Taniguchi, I1
Nakamura, S1
Shono, M1
Ogawa, H1
Livanov, GA1
Amagyrov, VP1
Batotsyrenov, BV1
Lodiagin, AN1
Batotsyrenova, KhV1
Ogawa, K1
Enomoto, I1
Ito, T1
Ban, M1
Hashimoto, H1
Sakai, K1
Meerson, FZ1
Manukhina, EB1
Dosmagambetova, RS1
Mizumura, T2
Nithipatikom, K2
Gross, GJ7
Yao, Z2
Pieper, GM2
Auchampach, JA3
Yamazaki, J2
Iida, M2
Igarashi, M1
Hosoi, H2
Ishiguro, S1
Hou, M1
Morishita, T2
Nakano, H2
Yabe, Y2
Koyama, N2
Guermonprez, JL1
Blin, P1
Peterlongo, F1
Roland, E1
Ohsawa, H1
Uchi, T1
Komatsu, H1
Galiè, N1
Guarnieri, C1
Ussia, GP1
Zimarino, M1
Traini, AM1
Parlangeli, R1
Vaona, I1
Branzi, A1
Magnani, B1
Ejima, J1
Kaneda, K1
Moriyama, H1
Ohmura, I1
Maruyama, T1
Kaji, Y1
Tsuda, Y1
Kanaya, S1
Fujino, T1
Niho, Y1
Kitakaze, M2
Minamino, T1
Node, K1
Komamura, K3
Shinozaki, Y1
Chujo, M1
Mori, H1
Inoue, M1
Hori, M2
Kamada, T1
Sakata, Y3
Kodama, K2
Ishikura, F2
Hasegawa, S1
Hirayama, A2
Lim, YJ1
Masuyama, T1
Schultz, JE1
Cavero, I1
Rioufol, G1
Ovize, M1
Loufoua, J1
Pop, C1
André-Fouät, X1
Minaire, Y1
Imagawa, J1
Baxter, GF1
Yellon, DM1
Ohno, Y1
Minatoguchi, S1
Uno, Y1
Kariya, T1
Arai, M1
Yamashita, K1
Fujiwara, T1
Fujiwara, H1
Kobayashi, Y1
Goto, Y1
Daikoku, S1
Itoh, A1
Miyazaki, S1
Ohshima, S1
Nonogi, H1
Haze, K1
Bernofsky, C1
Nunez, R2
Calva, E2
Marsh, M1
Marsch, M1
Briones, E1
López-Soriano, F1
Maruyama, M1
Warltier, DC2
van Woerkens, LJ1
Baas, NR1
van der Giessen, WJ1
Verdouw, PD1
Dzizinskiĭ, AA3
Katiubin, VP2
Kishida, H1
Tada, Y1
Tetsuoh, Y1
Yamazaki, Y1
Saito, T1
Fukuma, N1
Hata, N1
Yasutake, M1
Hayakawa, H2
Yokota, M2
Tsuzuki, J1
Inagaki, H1
Watanabe, M1
Matsunami, T1
Sotobata, I1
Hardman, HF1
Horisawa, T1
Iwase, M1
Miyahara, T1
Yoshida, J1
Kamihara, S1
Noda, S1
Tsunekawa, A1
Koide, M1
Tsuzuki, M1
Endo, T1
Nejima, J1
Kiuchi, K1
Fujita, S1
Kikuchi, K1
Okumura, H1
Ana'nev, AA1
Fuks, AR1
Severin, SE1
Chazov, EI1
Smetnev, AS1
Petrova, LI1
Tabak, VIa1
Ivashchenko, AG1
Zakin, AM1

Trials

5 trials available for niacinamide and Cardiovascular Stroke

ArticleYear
A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Diltiazem; Dose-Response Relationship

1993
Coronary dilating effects of intracoronary nicorandil. Comparison with isosorbide dinitrate.
    Japanese heart journal, 1995, Volume: 36, Issue:6

    Topics: Angina Pectoris; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Coronary Circulation; Coronary V

1995
Salutary effect of adjunctive intracoronary nicorandil administration on restoration of myocardial blood flow and functional improvement in patients with acute myocardial infarction.
    American heart journal, 1997, Volume: 133, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Contrast Media; Coronary Circulation; Coronary Vessels; Echocardiogr

1997
Cardioprotective effect of intravenous nicorandil in patients with successful reperfusion for acute myocardial infarction.
    Japanese circulation journal, 1998, Volume: 62, Issue:3

    Topics: Acute Disease; Anti-Arrhythmia Agents; Humans; Injections, Intravenous; Myocardial Infarction; Myoca

1998
[Effects of antioxidants and membrane protectors on clinical course and hemodynamics of patients with myocardial infarct].
    Rossiiskii meditsinskii zhurnal : organ Ministerstva zdravookhraneniia RSFSR, 1992, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chloroquine; Female; Humans; Male; Middle Age

1992

Other Studies

42 other studies available for niacinamide and Cardiovascular Stroke

ArticleYear
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
    Molecular pharmacology, 2008, Volume: 74, Issue:6

    Topics: Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Humans; Imidazoles; Isoquinolines; Kinetics; Male

2008
Cardioprotective effect of N-methylnicotinamide salt of pyruvate in experimental model of cardiac hypoxia.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:2

    Topics: Animals; Apolipoproteins E; Cardiotonic Agents; Creatine Kinase; Electrocardiography; Heart; Hypoxia

2018
[THE EFFECT OF CYTOFLAVIN ON PARAMETERS OF THE LEFT VENTRICULAR SYSTOLIC FUNCTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION.]
    Eksperimental'naia i klinicheskaia farmakologiia, 2017, Volume: 80, Issue:1

    Topics: Adult; Aged; Biomarkers; Cardiotonic Agents; Case-Control Studies; Coronary Vessels; Creatine Kinase

2017
VEGF-A and VEGF-B Coordinate the Arteriogenesis to Repair the Infarcted Heart with Vagus Nerve Stimulation.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:2

    Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Movement; Cell Proliferation;

2018
Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure.
    Genetics and molecular research : GMR, 2014, Jan-21, Volume: 13, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Cells, Cultured; Heart Failure; Male; Mice; Myoca

2014
Sorafenib cardiotoxicity increases mortality after myocardial infarction.
    Circulation research, 2014, May-23, Volume: 114, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cats; Cell Proliferation; Cells, Cultured; Disease Models

2014
Puerarin improves cardiac function through regulation of energy metabolism in Streptozotocin-Nicotinamide induced diabetic mice after myocardial infarction.
    Biochemical and biophysical research communications, 2015, Aug-07, Volume: 463, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Energy Metabolism; Heart; Isoflavones; Male; Mice; Mice, I

2015
[Three Patients with Acute Myocardial Infarction Associated with Targeted Therapy of Sorafenib for Metastatic Renal Cell Carcinoma : Case Report].
    Hinyokika kiyo. Acta urologica Japonica, 2015, Volume: 61, Issue:9

    Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Male; Middle Aged; Mol

2015
Methanolic seed extract of Vitis vinifera ameliorates oxidative stress, inflammation and ATPase dysfunction in infarcted and non-infarcted heart of streptozotocin-nicotinamide induced male diabetic rats.
    International journal of cardiology, 2016, Nov-01, Volume: 222

    Topics: Adenosine Triphosphatases; Animals; Diabetes Mellitus, Experimental; Grape Seed Extract; Inflammatio

2016
Sorafenib-induced acute myocardial infarction due to coronary artery spasm.
    Journal of cardiology, 2009, Volume: 54, Issue:3

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Coronary Vasospasm; Humans; K

2009
[Pharmacological correction of hypoxic and free-radical disorders in patients with acute myocardial infarction complicated by acute heart failure].
    Eksperimental'naia i klinicheskaia farmakologiia, 2010, Volume: 73, Issue:5

    Topics: Acute Disease; Critical Care; Drug Combinations; Flavin Mononucleotide; Fluorocarbons; Free Radicals

2010
SG-75 induction of increased coronary outflow and PGE1 from ischemic areas in dogs with experimental myocardial infarction.
    Japanese heart journal, 1982, Volume: 23, Issue:4

    Topics: Alprostadil; Animals; Coronary Circulation; Dinoprostone; Dogs; Indomethacin; Lactates; Myocardial I

1982
[Disorders of contractile function and adrenoreactivity of the portal vein in emotionally-painful stress and experimental myocardial infarct and their prevention by means of membrane protectors].
    Kardiologiia, 1984, Volume: 24, Issue:4

    Topics: Animals; Butylated Hydroxytoluene; Glucose; Humans; Male; Muscle, Smooth, Vascular; Myocardial Infar

1984
Effects of nicorandil and glyceryl trinitrate on infarct size, adenosine release, and neutrophil infiltration in the dog.
    Cardiovascular research, 1995, Volume: 29, Issue:4

    Topics: Adenosine; Animals; Cell Movement; Coronary Circulation; Dogs; Female; Male; Myocardial Infarction;

1995
The ATP-regulated potassium channel in ischemia-reperfusion injury.
    Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723

    Topics: Adenosine Triphosphate; Animals; Dogs; Glyburide; Ion Channel Gating; Myocardial Contraction; Myocar

1994
Evaluation of the efficacy of nicorandil in patients with ischemic heart disease by exercise Tl-201 myocardial SPECT.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Angioplasty, Balloon, Coronary; Antihypertensive Ag

1994
Anti-ischaemic actions of potassium channel openers in experimental myocardial ischaemia/reperfusion injury in dogs.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Animals; Antihypertensive Agents; Benzopyrans; Coronary Circulation; Dihydropyridines; Dogs; Female;

1993
Safety profile of an anti-anginal agent with potassium channel opening activity: an overview.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Coronary Circulation; Drug Monitoring; Electrocardi

1993
Study of the efficacy of nicorandil in patients with ischaemic heart disease using Exercise-T1-201 myocardial tomography.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:3

    Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Coronary Circu

1993
Limitation of myocardial infarct size by nicorandil after sustained ischemia in pigs.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Female; Glutathione; Heart Rate; Isosorbide Dinitrate; Male

1995
Infarct size-reducing effect of nicorandil is mediated by the KATP channel but not by its nitrate-like properties in dogs.
    Cardiovascular research, 1996, Volume: 32, Issue:2

    Topics: Adenosine; Animals; Dogs; Female; Glyburide; Ion Channel Gating; Male; Methylene Blue; Myocardial In

1996
Role of activation of ectosolic 5'-nucleotidase in the cardioprotection mediated by opening of K+c channels.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 2

    Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dogs; Enzyme Activation;

1996
Disappearance of the 'no-reflow' phenomenon after adjunctive intracoronary administration of nicorandil in a patient with acute myocardial infarction.
    Japanese circulation journal, 1997, Volume: 61, Issue:5

    Topics: Coronary Circulation; Coronary Vessels; Humans; Injections; Male; Middle Aged; Myocardial Infarction

1997
Glibenclamide-induced blockade of ischemic preconditioning is time dependent in intact rat heart.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Animals; Antihypertensive Agents; Blood Glucose; Glyburide; Heart; Hemodynamics; Hypotension; Ischem

1997
Ventricular fibrillation in preconditioned pig hearts: role of K+ATP channels.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Action Potentials; Animals; Blood Glucose; Blood Pressure; Glyburide; Heart; Heart Rate; Ischemic Pr

1997
Myocardial protection afforded by nicorandil and ischaemic preconditioning in a rabbit infarct model in vivo.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Hemodynamics; Ischemic Preconditioning, Myo

1998
Nicorandil reduces myocardial infarct size by opening the K(ATP) channel in rabbits.
    International journal of cardiology, 1997, Dec-19, Volume: 62, Issue:3

    Topics: Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Glyburide; Heart Ra

1997
Inhibition of the activity of poly (ADP-ribose) polymerase in ischemia-reperfusion injury.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Animals; DNA Damage; Drug Design; Energy Metabolism; Enzyme Inhibitors; Feedback; Humans; Ischemia;

2000
Vitamin therapy for infarction.
    The American journal of cardiology, 1979, Volume: 44, Issue:3

    Topics: Humans; Myocardial Infarction; Niacinamide

1979
Nicotinamide adenine dinucleotide degradation in infarcted cardiac muscle.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 10

    Topics: Animals; Dogs; Myocardial Infarction; Myocardium; NAD; NAD+ Nucleosidase; Niacinamide; Subcellular F

1975
NAD glycohydrolase activity in hearts with acute experimental infarction.
    The American journal of physiology, 1976, Volume: 231, Issue:4

    Topics: Animals; Disease Models, Animal; Dogs; Myocardial Infarction; Myocardium; NAD; NAD+ Nucleosidase; Ni

1976
Cardioprotective effects of nicorandil.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3

    Topics: Animals; Benzopyrans; Coronary Circulation; Dihydropyridines; Dogs; Female; Heart; In Vitro Techniqu

1992
Cardiovascular effects of the novel potassium channel opener bimakalim in conscious pigs after myocardial infarction: a comparative study with nicorandil.
    Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:4

    Topics: Animals; Antihypertensive Agents; Benzopyrans; Dihydropyridines; Hemodynamics; Myocardial Infarction

1992
[Clinical course and necrotic area size in patients with myocardial infarct receiving combined treatment including antioxidants and membrane-protecting agents].
    Kardiologiia, 1991, Volume: 31, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Drug Therapy, Combination; Female; Humans; Mal

1991
A new strategy for the reduction of acute myocardial infarction in variant angina.
    American heart journal, 1991, Volume: 122, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris, Variant; Angioplasty, Balloon, Coronary; Calcium Ch

1991
Effect of low grade exercise training and a vasodilator on cardiac function in patients with recent myocardial infarction.
    Japanese circulation journal, 1990, Volume: 54, Issue:11

    Topics: Cardiac Output; Exercise Therapy; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarc

1990
Comparative effects of nicorandil, a nicotinamide nitrate derivative, and nifedipine on myocardial reperfusion injury in dogs.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:5

    Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Male; Myocardial Contraction; Myocardia

1987
Effects of a new vasodilator, nicorandil, on exercise-induced impairment of left ventricular function in patients with old myocardial infarction.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Adult; Coronary Circulation; Exercise Test; Heart; Heart Ventricles; Hemodynamics; Humans; Male; Mid

1987
Reduction of size of myocardial infarction with nicorandil, a new antianginal drug, after coronary artery occlusion in dogs.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:5

    Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; Male; Myocardial Infarction; Niacinamide; Nic

1988
[Effect of membrane protectors on the diastolic function of the heart in patients with acute myocardial infarction].
    Kardiologiia, 1989, Volume: 29, Issue:9

    Topics: Adult; Aged; Cell Membrane; Diastole; Female; Heart Ventricles; Humans; Male; Middle Aged; Myocardia

1989
[Basic directions in the study of the biochemistry of the myocardium].
    Kardiologiia, 1967, Volume: 7, Issue:11

    Topics: Adaptation, Physiological; Animals; Camphor; Cardiac Glycosides; Cardiomegaly; Cardiovascular Diseas

1967
[Use of neuroleptoanalgesia with thalamonal in myocardial infarct patients during the painful period].
    Kardiologiia, 1969, Volume: 9, Issue:7

    Topics: Adult; Aged; Angina Pectoris; Benperidol; Female; Humans; Male; Middle Aged; Myocardial Infarction;

1969