Page last updated: 2024-10-19

niacinamide and Cardiotoxicity

niacinamide has been researched along with Cardiotoxicity in 9 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.

Research Excerpts

ExcerptRelevanceReference
"Sorafenib is associated with adverse cardiac effects, including left ventricular dysfunction."7.81Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity. ( Kawabata, M; Kuroyanagi, J; Miyabe, M; Nishimura, Y; Shimada, Y; Tanaka, T; Umemoto, N; Zhang, B, 2015)
" The underlying mechanism of these adverse cardiac effects is largely unknown."5.51Ponatinib-induced cardiotoxicity: delineating the signalling mechanisms and potential rescue strategies. ( Becker, JR; Force, T; Galindo, CL; Glennon, MS; Gupte, M; Lal, H; Singh, AP; Umbarkar, P; Zhang, Q, 2019)
" However, the use of some SMKIs, such as sorafenib (SO), has been plagued by their cardiotoxicity that has been frequently observed in treated patients."3.85Supramolecular alleviation of cardiotoxicity of a small-molecule kinase inhibitor. ( Bardelang, D; Huang, Q; Lee, SMY; Wang, C; Wang, R; Yang, X, 2017)
"Sorafenib is associated with adverse cardiac effects, including left ventricular dysfunction."3.81Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity. ( Kawabata, M; Kuroyanagi, J; Miyabe, M; Nishimura, Y; Shimada, Y; Tanaka, T; Umemoto, N; Zhang, B, 2015)
" The underlying mechanism of these adverse cardiac effects is largely unknown."1.51Ponatinib-induced cardiotoxicity: delineating the signalling mechanisms and potential rescue strategies. ( Becker, JR; Force, T; Galindo, CL; Glennon, MS; Gupte, M; Lal, H; Singh, AP; Umbarkar, P; Zhang, Q, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Podyacheva, E1
Toropova, Y1
Zou, L1
Liang, B1
Gao, Y1
Ye, T1
Li, M1
Zhang, Y2
Lu, Q1
Hu, X1
Li, H1
Yuan, Y1
Xing, D1
Hua, H1
Zhao, Q1
Xia, J1
Dai, QL1
Bai, SR1
Wang, XB1
Zhou, M1
Yang, X1
Huang, Q1
Bardelang, D1
Wang, C1
Lee, SMY1
Wang, R1
Stuhlmiller, TJ1
Zawistowski, JS1
Chen, X1
Sciaky, N1
Angus, SP1
Hicks, ST1
Parry, TL1
Huang, W1
Beak, JY1
Willis, MS1
Johnson, GL1
Jensen, BC1
Singh, AP1
Glennon, MS1
Umbarkar, P1
Gupte, M1
Galindo, CL1
Zhang, Q1
Force, T1
Becker, JR1
Lal, H1
Zheng, D1
Zheng, M1
Cao, T1
Wang, G1
Zhang, L1
Ni, R1
Brockman, J1
Zhong, H1
Fan, GC1
Peng, T1
Kawabata, M1
Umemoto, N1
Shimada, Y1
Nishimura, Y1
Zhang, B1
Kuroyanagi, J1
Miyabe, M1
Tanaka, T1
Abdel-Rahman, O1
Fouad, M1

Reviews

3 reviews available for niacinamide and Cardiotoxicity

ArticleYear
Nicotinamide Riboside for the Prevention and Treatment of Doxorubicin Cardiomyopathy. Opportunities and Prospects.
    Nutrients, 2021, Sep-28, Volume: 13, Issue:10

    Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Cardiomyopathies; Cardiotonic Agents; Cardiotoxici

2021
Nicotinic Acid Riboside Regulates Nrf-2/P62-Related Oxidative Stress and Autophagy to Attenuate Doxorubicin-Induced Cardiomyocyte Injury.
    BioMed research international, 2022, Volume: 2022

    Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Cardiotonic Agents; Cardiotoxicity; Dexrazoxan

2022
Risk of cardiovascular toxicities in patients with solid tumors treated with sorafenib: an updated systematic review and meta-analysis.
    Future oncology (London, England), 2014, Volume: 10, Issue:12

    Topics: Antineoplastic Agents; Cardiotoxicity; Cardiovascular Diseases; Clinical Trials, Phase II as Topic;

2014

Other Studies

6 other studies available for niacinamide and Cardiotoxicity

ArticleYear
Peficitinib ameliorates doxorubicin-induced cardiotoxicity by suppressing cellular senescence and enhances its antitumor activity.
    International immunopharmacology, 2023, Volume: 122

    Topics: Animals; Apoptosis; Cardiotoxicity; Cellular Senescence; Doxorubicin; Humans; Mice; Myocytes, Cardia

2023
Supramolecular alleviation of cardiotoxicity of a small-molecule kinase inhibitor.
    Organic & biomolecular chemistry, 2017, Oct-04, Volume: 15, Issue:38

    Topics: Animals; Antineoplastic Agents; Bridged-Ring Compounds; Cardiotoxicity; Cell Line, Tumor; Cell Survi

2017
Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Transducer and Activator of Transcription and Epidermal Growth Factor Recepto
    Journal of the American Heart Association, 2017, Oct-19, Volume: 6, Issue:10

    Topics: Animals; Antineoplastic Agents; Cardiotoxicity; Cells, Cultured; Dose-Response Relationship, Drug; E

2017
Ponatinib-induced cardiotoxicity: delineating the signalling mechanisms and potential rescue strategies.
    Cardiovascular research, 2019, 04-15, Volume: 115, Issue:5

    Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Apoptosis; Cardiotoxicity; Cells, Cul

2019
Nicotinamide riboside promotes autolysosome clearance in preventing doxorubicin-induced cardiotoxicity.
    Clinical science (London, England : 1979), 2019, 07-15, Volume: 133, Issue:13

    Topics: Animals; Antioxidants; Autophagy; Cardiotoxicity; Cells, Cultured; Cytoprotection; Disease Models, A

2019
Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 143, Issue:2

    Topics: Adult; Animals; Antineoplastic Agents; Cardiotoxicity; Down-Regulation; Glycoproteins; Heart; Humans

2015