niacinamide has been researched along with Cardiac Remodeling, Ventricular in 8 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of the novel multikinase inhibitor sorafenib, which inhibits tyrosine kinases as well as serine/threonine kinases, in comparison to imatinib, a tyrosine kinase inhibitor, on hemodynamics, pulmonary and right ventricular (RV) remodeling, and downstream signaling in experimental pulmonary hypertension." | 7.74 | Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling. ( Busch, AE; Dony, E; Ellinghaus, P; Ghofrani, HA; Grimminger, F; Klein, M; Milting, H; Nikolova, S; Pullamsetti, SS; Riedl, B; Savai, R; Schäfer, S; Schermuly, RT; Weissmann, N, 2008) |
| "We investigated the effects of the novel multikinase inhibitor sorafenib, which inhibits tyrosine kinases as well as serine/threonine kinases, in comparison to imatinib, a tyrosine kinase inhibitor, on hemodynamics, pulmonary and right ventricular (RV) remodeling, and downstream signaling in experimental pulmonary hypertension." | 3.74 | Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling. ( Busch, AE; Dony, E; Ellinghaus, P; Ghofrani, HA; Grimminger, F; Klein, M; Milting, H; Nikolova, S; Pullamsetti, SS; Riedl, B; Savai, R; Schäfer, S; Schermuly, RT; Weissmann, N, 2008) |
| "Cardiac hypertrophy is a compensatory response to pressure overload, which eventually leads to heart failure." | 1.62 | Nicotinamide Riboside Alleviates Cardiac Dysfunction and Remodeling in Pressure Overload Cardiac Hypertrophy. ( Feng, J; Gong, J; Lin, X; Liu, J; Ma, S; Nie, S; Tang, Y; Wang, L, 2021) |
| "Cardiac hypertrophy is a major risk factor for heart failure." | 1.43 | Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib. ( Cantarella, D; Cimino, J; Comoglio, PM; Crepaldi, T; Fontani, L; Gallo, S; Gatti, S; Medico, E; Morello, M; Natale, M; Ponzetto, A; Sala, V; Vigna, E, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, S | 1 |
| Feng, J | 1 |
| Lin, X | 1 |
| Liu, J | 1 |
| Tang, Y | 1 |
| Nie, S | 1 |
| Gong, J | 1 |
| Wang, L | 2 |
| Pei, Z | 1 |
| Wang, F | 1 |
| Wang, K | 1 |
| Visnagri, A | 1 |
| Oexner, RR | 1 |
| Kmiotek-Wasylewska, K | 1 |
| Zhang, M | 1 |
| Zoccarato, A | 1 |
| Shah, AM | 1 |
| Tannous, C | 1 |
| Deloux, R | 1 |
| Karoui, A | 1 |
| Mougenot, N | 1 |
| Burkin, D | 1 |
| Blanc, J | 1 |
| Coletti, D | 1 |
| Lavery, G | 1 |
| Li, Z | 1 |
| Mericskay, M | 1 |
| Leong, ZP | 1 |
| Hikasa, Y | 1 |
| Sala, V | 1 |
| Gallo, S | 1 |
| Gatti, S | 1 |
| Medico, E | 1 |
| Vigna, E | 1 |
| Cantarella, D | 1 |
| Fontani, L | 1 |
| Natale, M | 1 |
| Cimino, J | 1 |
| Morello, M | 1 |
| Comoglio, PM | 1 |
| Ponzetto, A | 1 |
| Crepaldi, T | 1 |
| Klein, M | 1 |
| Schermuly, RT | 2 |
| Ellinghaus, P | 1 |
| Milting, H | 1 |
| Riedl, B | 1 |
| Nikolova, S | 1 |
| Pullamsetti, SS | 2 |
| Weissmann, N | 2 |
| Dony, E | 1 |
| Savai, R | 1 |
| Ghofrani, HA | 2 |
| Grimminger, F | 2 |
| Busch, AE | 1 |
| Schäfer, S | 1 |
| Kojonazarov, B | 1 |
| Sydykov, A | 1 |
| Luitel, H | 1 |
| Dahal, BK | 1 |
| Kosanovic, D | 1 |
| Tian, X | 1 |
| Majewski, M | 1 |
| Baumann, C | 1 |
| Evans, S | 1 |
| Phillips, P | 1 |
| Fairman, D | 1 |
| Davie, N | 1 |
| Wayman, C | 1 |
| Kilty, I | 1 |
| Seeger, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Untersuchung Des Einflusses PAH-spezifischer Medikation Auf Die rechtsventrikuläre Funktion Bei Patienten Mit Pulmonaler Arterieller Hypertonie (PAH) Unter Basalen Bedingungen[NCT03362047] | Phase 2 | 30 participants (Anticipated) | Interventional | 2018-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for niacinamide and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Nicotinamide Adenosine Dinucleotide Phosphate Oxidase-Mediated Signaling in Cardiac Remodeling.
Topics: Adenine Nucleotides; Adenosine; Endothelial Cells; Humans; NADP; NADPH Oxidase 4; NADPH Oxidases; Ni | 2023 |
7 other studies available for niacinamide and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Nicotinamide Riboside Alleviates Cardiac Dysfunction and Remodeling in Pressure Overload Cardiac Hypertrophy.
Topics: Animals; Apoptosis; Atrial Remodeling; Cardiomegaly; Inflammasomes; Male; Mice; Mice, Inbred C57BL; | 2021 |
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging.
Topics: Aging; Animals; Antioxidants; Heart; Humans; Mice; NAD; Niacinamide; Ventricular Remodeling | 2022 |
NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging.
Topics: Aging; Animals; Cardiomegaly; Cardiomyopathy, Dilated; Cytosol; Disease Models, Animal; Electrocardi | 2021 |
Effects of toceranib compared with sorafenib on monocrotaline-induced pulmonary arterial hypertension and cardiopulmonary remodeling in rats.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Autophagy; Disease Models, Animal; Dose-Respons | 2018 |
Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib.
Topics: Animals; Cardiomegaly; Cell Line; Cytoskeleton; Disease Models, Animal; Extracellular Matrix; Gap Ju | 2016 |
Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.
Topics: Animals; Benzamides; Benzenesulfonates; Blood Pressure; Disease Progression; Extracellular Signal-Re | 2008 |
Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling.
Topics: Animals; Dose-Response Relationship, Drug; Familial Primary Pulmonary Hypertension; Hypertension, Pu | 2013 |