Page last updated: 2024-10-19

niacinamide and Carcinoma, Adenoid Cystic

niacinamide has been researched along with Carcinoma, Adenoid Cystic in 2 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Carcinoma, Adenoid Cystic: Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Sorafenib is the first anti-angiogenic agent to demonstrate activity in RMSGC patients, particularly in some histotypes such as HG-MEC, SDC and adenocarcinoma, NOS."5.22A phase II study of sorafenib in recurrent and/or metastatic salivary gland carcinomas: Translational analyses and clinical impact. ( Alfieri, S; Bergamini, C; Bossi, P; Civelli, E; Cortelazzi, B; Dagrada, GP; Granata, R; Imbimbo, M; Licitra, L; Lo Vullo, S; Locati, LD; Mariani, L; Mirabile, A; Morosi, C; Orlandi, E; Perrone, F; Pilotti, S; Quattrone, P; Resteghini, C; Saibene, G, 2016)
"Sorafenib was only reasonably well tolerated, and 13 patients (57%) experienced grade 3 toxicity."2.80Phase II trial of sorafenib in advanced salivary adenoid cystic carcinoma of the head and neck. ( Bonington, S; Denton, K; Homer, J; Lee, LW; Mak, SK; Silva, P; Slevin, NJ; Swindell, R; Sykes, AJ; Thomson, DJ; Yap, BK, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thomson, DJ1
Silva, P1
Denton, K1
Bonington, S1
Mak, SK1
Swindell, R1
Homer, J1
Sykes, AJ1
Lee, LW1
Yap, BK1
Slevin, NJ1
Locati, LD1
Perrone, F1
Cortelazzi, B1
Bergamini, C1
Bossi, P1
Civelli, E1
Morosi, C1
Lo Vullo, S1
Imbimbo, M1
Quattrone, P1
Dagrada, GP1
Granata, R1
Resteghini, C1
Mirabile, A1
Alfieri, S1
Orlandi, E1
Mariani, L1
Saibene, G1
Pilotti, S1
Licitra, L1

Trials

2 trials available for niacinamide and Carcinoma, Adenoid Cystic

ArticleYear
Phase II trial of sorafenib in advanced salivary adenoid cystic carcinoma of the head and neck.
    Head & neck, 2015, Volume: 37, Issue:2

    Topics: Adult; Aged; Carcinoma, Adenoid Cystic; Disease Progression; Female; Humans; Male; Middle Aged; Niac

2015
A phase II study of sorafenib in recurrent and/or metastatic salivary gland carcinomas: Translational analyses and clinical impact.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 69

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Carcinoma, Mucoepider

2016