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niacinamide and Bleeding

niacinamide has been researched along with Bleeding in 18 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Treatment with the VEGFR tyrosine-kinase inhibitors sunitinib and sorafenib is associated with a significant increase in risk of bleeding."8.85Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. ( Choueiri, TK; Je, Y; Schutz, FA, 2009)
"Sorafenib is the standard of care for advanced hepatocellular carcinoma (HCC)."7.81Sorafenib use in elderly patients with hepatocellular carcinoma: caution about use of platelet aggregation inhibitors. ( Boucher, E; Brunot, A; Cattenoz, C; Crouzet, L; Edeline, J; Gédouin, D; Guillygomarc'h, A; Larible, C; Latournerie, M; Le Roy, F; Le Sourd, S, 2015)
"Sorafenib is a multikinase inhibitor recently introduced in the therapy of patients with advanced HCC."5.37Sorafenib, risk of bleeding and spontaneous rupture of hepatocellular carcinoma. A clinical case. ( Caravetta, A; Guarino, R; Mollo, F; Peluso, L; Rombolà, F; Spinoso, A, 2011)
"This analysis of both randomized and nonrandomized studies evaluating an antiangiogenic agent in HCC showed that whereas the use of sorafenib was associated with an increased risk of bleeding in HCC, this was primarily for lower-grade events and similar in magnitude to the risk encountered in RCC."4.89Hemorrhagic events in hepatocellular carcinoma patients treated with antiangiogenic therapies. ( Duffy, A; Greten, TF; Wilkerson, J, 2013)
"Treatment with the VEGFR tyrosine-kinase inhibitors sunitinib and sorafenib is associated with a significant increase in risk of bleeding."4.85Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. ( Choueiri, TK; Je, Y; Schutz, FA, 2009)
"Sorafenib is the standard of care for advanced hepatocellular carcinoma (HCC)."3.81Sorafenib use in elderly patients with hepatocellular carcinoma: caution about use of platelet aggregation inhibitors. ( Boucher, E; Brunot, A; Cattenoz, C; Crouzet, L; Edeline, J; Gédouin, D; Guillygomarc'h, A; Larible, C; Latournerie, M; Le Roy, F; Le Sourd, S, 2015)
" He was diagnosed with hepatocellular carcinoma in June 2007 and began treatment with sorafenib 200 mg daily in September 2007."3.75Elevated International Normalized Ratio associated with concurrent use of sorafenib and warfarin. ( Montalvo, RO; Moretti, LV, 2009)
" Common adverse events (AEs) were also studied."2.52Efficacy and safety of angiogenesis inhibitors in advanced non-small cell lung cancer: a systematic review and meta-analysis. ( Chen, Y; Hong, S; Luo, S; Tan, M; Wang, S; Zhang, L, 2015)
"Although both reached severe aplasia of the bone marrow without blastic infiltration, death occurred with neutropenic sepsis."2.52Hypertension and Life-Threatening Bleeding in Children with Relapsed Acute Myeloblastic Leukemia Treated with FLT3 Inhibitors. ( Aydınok, Y; Balkan, C; Karadaş, N; Kavaklı, K; Önder Siviş, Z; Yılmaz Karapınar, D, 2015)
" With expanded clinical experience with this class of agents has come the increasing recognition of the diverse adverse effects related to disturbance of VEGF-dependent physiological functions and homeostasis in the cardiovascular and renal systems, as well as wound healing and tissue repair."2.45Adverse effects of anticancer agents that target the VEGF pathway. ( Chen, HX; Cleck, JN, 2009)
"Advances in understanding the role of vascular endothelial growth factor (VEGF) in normal physiology are giving insight into the basis of adverse effects attributed to the use of VEGF inhibitors in clinical oncology."2.44Mechanisms of adverse effects of anti-VEGF therapy for cancer. ( Kamba, T; McDonald, DM, 2007)
"Sorafenib is a multikinase inhibitor recently introduced in the therapy of patients with advanced HCC."1.37Sorafenib, risk of bleeding and spontaneous rupture of hepatocellular carcinoma. A clinical case. ( Caravetta, A; Guarino, R; Mollo, F; Peluso, L; Rombolà, F; Spinoso, A, 2011)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's0 (0.00)18.2507
2000's6 (33.33)29.6817
2010's8 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hong, S1
Tan, M1
Wang, S1
Luo, S1
Chen, Y1
Zhang, L1
Edeline, J1
Crouzet, L1
Le Sourd, S1
Larible, C1
Brunot, A1
Le Roy, F1
Cattenoz, C1
Latournerie, M1
Gédouin, D1
Guillygomarc'h, A1
Boucher, E1
Yılmaz Karapınar, D1
Karadaş, N1
Önder Siviş, Z1
Balkan, C1
Kavaklı, K1
Aydınok, Y1
Snider, KL1
Maitland, ML1
Chen, HX1
Cleck, JN1
Je, Y1
Schutz, FA1
Choueiri, TK1
Moretti, LV1
Montalvo, RO1
Minor, DR1
Rübsam, K1
Flaig, MJ1
Ruzicka, T1
Prinz, JC1
Rombolà, F1
Caravetta, A1
Mollo, F1
Spinoso, A1
Peluso, L1
Guarino, R1
Fabries, P1
Pauleau, G1
Brardjanian, S1
Artéaga, C1
Guisset, M1
Coton, T1
Duffy, A1
Wilkerson, J1
Greten, TF1
Robert, C1
Faivre, S1
Raymond, E1
Armand, JP1
Escudier, B1
Kamba, T1
McDonald, DM1
Podorozhnyĭ, AP1
Fujinaga, Y1
Grote, W1
Schneider, H1
Cervos-Navarro, J1

Reviews

7 reviews available for niacinamide and Bleeding

ArticleYear
Efficacy and safety of angiogenesis inhibitors in advanced non-small cell lung cancer: a systematic review and meta-analysis.
    Journal of cancer research and clinical oncology, 2015, Volume: 141, Issue:5

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2015
Hypertension and Life-Threatening Bleeding in Children with Relapsed Acute Myeloblastic Leukemia Treated with FLT3 Inhibitors.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:3

    Topics: Acidosis; Acute Kidney Injury; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols;

2015
Cardiovascular toxicities: clues to optimal administration of vascular endothelial growth factor signaling pathway inhibitors.
    Targeted oncology, 2009, Volume: 4, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineo

2009
Adverse effects of anticancer agents that target the VEGF pathway.
    Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2009
Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials.
    The Lancet. Oncology, 2009, Volume: 10, Issue:10

    Topics: Antineoplastic Agents; Benzenesulfonates; Clinical Trials as Topic; Hemorrhage; Humans; Incidence; I

2009
Hemorrhagic events in hepatocellular carcinoma patients treated with antiangiogenic therapies.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:3

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Hepatocellular; Hemorrhage; Humans; Incid

2013
Mechanisms of adverse effects of anti-VEGF therapy for cancer.
    British journal of cancer, 2007, Jun-18, Volume: 96, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2007

Other Studies

11 other studies available for niacinamide and Bleeding

ArticleYear
Sorafenib use in elderly patients with hepatocellular carcinoma: caution about use of platelet aggregation inhibitors.
    Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Agents; Asthenia; Carcinoma, Hepatocellular; Comorbid

2015
Elevated International Normalized Ratio associated with concurrent use of sorafenib and warfarin.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, Dec-01, Volume: 66, Issue:23

    Topics: Aged; Anticoagulants; Benzenesulfonates; Carcinoma, Hepatocellular; Drug Interactions; Hemorrhage; H

2009
Risk of bleeding not increased by sorafenib or sunitinib.
    The Lancet. Oncology, 2010, Volume: 11, Issue:2

    Topics: Antineoplastic Agents; Benzenesulfonates; Hemorrhage; Humans; Indoles; Neoplasms; Niacinamide; Pheny

2010
Erythema marginatum hemorrhagicum: a unique cutaneous side effect of sorafenib.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:6

    Topics: Aged; Benzenesulfonates; Carcinoma, Hepatocellular; Erythema; Hemorrhage; Humans; Liver Neoplasms; M

2011
Sorafenib, risk of bleeding and spontaneous rupture of hepatocellular carcinoma. A clinical case.
    Acta medica (Hradec Kralove), 2011, Volume: 54, Issue:4

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Hemorrhage; Humans; Liver

2011
[Metastatic adrenal necrosis under sorafenib treatment for hepatocellular carcinoma].
    Presse medicale (Paris, France : 1983), 2013, Volume: 42, Issue:2

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Antineoplastic Agents; Carcinoma, H

2013
Subungual splinter hemorrhages: a clinical window to inhibition of vascular endothelial growth factor receptors?
    Annals of internal medicine, 2005, Aug-16, Volume: 143, Issue:4

    Topics: Antineoplastic Agents; Benzenesulfonates; Hemorrhage; Humans; Indoles; Nail Diseases; Niacinamide; P

2005
[Vitamin B1, B2, PP, B6 and C metabolism in iron-deficiency anemia].
    Vrachebnoe delo, 1982, Issue:10

    Topics: Adolescent; Adult; Anemia, Hypochromic; Ascorbic Acid; Female; Free Radicals; Hemorrhage; Humans; Ma

1982
[Effect of Inacin capsule for eye disease].
    Nihon ganka kiyo, 1968, Volume: 19, Issue:3

    Topics: Adult; Aged; Capsules; Eye Diseases; Female; Hemorrhage; Humans; Iodides; Male; Middle Aged; Niacina

1968
[Experiments on the induction and prevention of malformations in rabbits].
    Zeitschrift fur Morphologie und Anthropologie, 1972, Volume: 63, Issue:3

    Topics: Abnormalities, Drug-Induced; Amines; Animals; Animals, Newborn; Antimetabolites; Cell Division; Cong

1972
Acute gliopathy in spinal cord and brain stem induced by 6-aminonicotinamide.
    Acta neuropathologica, 1974, Feb-07, Volume: 27, Issue:1

    Topics: Animals; Brain Stem; Cats; Cell Nucleus; Cerebellum; Cranial Nerves; Cytoplasm; Endoplasmic Reticulu

1974