Page last updated: 2024-10-19

niacinamide and Angiosarcoma

niacinamide has been researched along with Angiosarcoma in 8 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Sorafenib showed limited antitumor activity in pretreated patients only, for both visceral and superficial angiosarcoma, but tumor control was of short duration."9.16Sorafenib for patients with advanced angiosarcoma: a phase II Trial from the French Sarcoma Group (GSF/GETO). ( Bay, JO; Blay, JY; Bompas, E; Bousquet, G; Chevreau, C; Clisant, S; Collard, O; Cupissol, D; Fournier, C; Gauthier, E; Isambert, N; Italiano, A; Le Cesne, A; Lemaitre, L; Penel, N; Piperno-Neumann, S; Ray-Coquard, I; Robin, YM, 2012)
"We have carried out a stratified phase II study of sorafenib (So) in patients with advanced angiosarcoma (nā€‰=ā€‰32) and epithelioid hemangioendothelioma (nā€‰=ā€‰13)."5.19Low level of baseline circulating VEGF-A is associated with better outcome in patients with vascular sarcomas receiving sorafenib: an ancillary study from a phase II trial. ( Bal-Mahieu, C; Baldeyrou, B; Bay, JO; Blay, JY; Bompas, E; Chevreau, C; Clisant, S; Fournier, C; Italiano, A; Lansiaux, A; Le Cesne, A; Penel, N; Piperno-Neumann, S; Ray-Coquard, I; Robin, YM, 2014)
"Sorafenib showed limited antitumor activity in pretreated patients only, for both visceral and superficial angiosarcoma, but tumor control was of short duration."5.16Sorafenib for patients with advanced angiosarcoma: a phase II Trial from the French Sarcoma Group (GSF/GETO). ( Bay, JO; Blay, JY; Bompas, E; Bousquet, G; Chevreau, C; Clisant, S; Collard, O; Cupissol, D; Fournier, C; Gauthier, E; Isambert, N; Italiano, A; Le Cesne, A; Lemaitre, L; Penel, N; Piperno-Neumann, S; Ray-Coquard, I; Robin, YM, 2012)
"Angiosarcoma is a rare neoplasm of endothelial origin that has limited treatment options and poor five-year survival."1.39Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma. ( Andersen, NJ; Baker, LH; Boguslawski, EA; Dawes, MJ; Duesbery, NS; Dykema, KJ; Froman, RE; Furge, KA; Kamstock, DA; Kitchell, BE; Krivochenitser, RI; Nickoloff, BJ; Thomas, DG, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersen, NJ1
Nickoloff, BJ1
Dykema, KJ1
Boguslawski, EA1
Krivochenitser, RI1
Froman, RE1
Dawes, MJ1
Baker, LH1
Thomas, DG1
Kamstock, DA1
Kitchell, BE1
Furge, KA1
Duesbery, NS1
Penel, N2
Ray-Coquard, I2
Bal-Mahieu, C1
Chevreau, C2
Le Cesne, A2
Italiano, A2
Bompas, E2
Clisant, S2
Baldeyrou, B1
Lansiaux, A1
Robin, YM2
Bay, JO2
Piperno-Neumann, S2
Blay, JY2
Fournier, C2
Rothweiler, S1
Dill, MT1
Terracciano, L1
Makowska, Z1
Quagliata, L1
Hlushchuk, R1
Djonov, V1
Heim, MH1
Semela, D1
Donghi, D1
Dummer, R1
Cozzio, A1
Sleijfer, S1
Bousquet, G1
Isambert, N1
Lemaitre, L1
Gauthier, E1
Collard, O1
Cupissol, D1
Tamiya, H1
Kamo, R1
Kumei, A1
Yanagihara, S1
Ishii, M1
Kobayashi, H1
Ono, S1
Tanioka, M1
Fujisawa, A1
Tanizaki, H1
Miyachi, Y1
Matsumura, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Multicenter Stratified Study Evaluating the Efficacy and Toxicity of Sorafenib in Treating Locally Advanced or Metastatic Angiosarcomas That Are Not Accessible to Curative Surgery[NCT00874874]Phase 296 participants (Anticipated)Interventional2008-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for niacinamide and Angiosarcoma

ArticleYear
Low level of baseline circulating VEGF-A is associated with better outcome in patients with vascular sarcomas receiving sorafenib: an ancillary study from a phase II trial.
    Targeted oncology, 2014, Volume: 9, Issue:3

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Enzyme-Linked Immunosorbent Assay; Hemangioendothelioma, E

2014
Sorafenib for patients with advanced angiosarcoma: a phase II Trial from the French Sarcoma Group (GSF/GETO).
    The oncologist, 2012, Volume: 17, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Endpoint Determination; Fe

2012

Other Studies

6 other studies available for niacinamide and Angiosarcoma

ArticleYear
Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:9

    Topics: Animals; Antineoplastic Agents; Benzamides; Cell Proliferation; Diphenylamine; Disease Models, Anima

2013
Generation of a murine hepatic angiosarcoma cell line and reproducible mouse tumor model.
    Laboratory investigation; a journal of technical methods and pathology, 2015, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Di

2015
Complete remission in a patient with multifocal metastatic cutaneous angiosarcoma with a combination of paclitaxel and sorafenib.
    The British journal of dermatology, 2010, Volume: 162, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Head and Neck Neoplasms; He

2010
Phase II studies in soft tissue sarcoma: time for reappraisal.
    The oncologist, 2012, Volume: 17, Issue:2

    Topics: Antineoplastic Agents; Benzenesulfonates; Female; Hemangiosarcoma; Humans; Male; Niacinamide; Phenyl

2012
Partial response of angiosarcoma of the scalp to sorafenib: association with decreased expression of vascular endothelial growth factors and their receptors.
    Clinical and experimental dermatology, 2012, Volume: 37, Issue:7

    Topics: Antineoplastic Agents; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Male; Middle Aged; Niacinam

2012
Angiosarcoma of the scalp successfully treated with a single therapy of sorafenib.
    Archives of dermatology, 2012, Volume: 148, Issue:6

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Female; Head and Neck Neoplasms; Hemangiosarcoma; Hu

2012