Page last updated: 2024-10-19

niacinamide and Aging

niacinamide has been researched along with Aging in 105 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"We demonstrated that post-laser topical application of ADSC-CM in combination with niacinamide has anti-aging effect on skin."9.41Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy. ( Chung, KB; Kim, J; Kim, S; Lee, JH; Lee, YI, 2021)
" This formulation also features niacinamide and terminalia chebula to further support the anti-aging benefits of retinol."8.12Facial Aging Improvement Case Study Using a Novel Combination of Retinol, Niacinamide, and Terminalia Chebula. ( Adams-Woodford, A; Ayres, P; Diaz, I; Giancola, G; Handler, M, 2022)
"Sorafenib is the standard of care for advanced hepatocellular carcinoma (HCC)."7.81Sorafenib use in elderly patients with hepatocellular carcinoma: caution about use of platelet aggregation inhibitors. ( Boucher, E; Brunot, A; Cattenoz, C; Crouzet, L; Edeline, J; Gédouin, D; Guillygomarc'h, A; Larible, C; Latournerie, M; Le Roy, F; Le Sourd, S, 2015)
"The aim of this study was to determine whether skeletal muscle depletion predicts the prognosis of patients with hepatocellular carcinoma (HCC) that is being treated with sorafenib."7.81Skeletal muscle depletion predicts the prognosis of patients with hepatocellular carcinoma treated with sorafenib. ( Hanai, T; Ideta, T; Imai, K; Kochi, T; Miyazaki, T; Shimizu, M; Shiraki, M; Suetsugu, A; Takai, K, 2015)
" This review provides renewed insights regarding the clinical utility and benefits of NAD+ precursors, namely nicotinamide (NAM), nicotinic acid (NA), nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), in attenuating NAD+ decline and phenotypic characterization of age-related disorders, including metabolic, cardiovascular and neurodegenerative diseases."5.41Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders. ( Braidy, N; Helman, T, 2023)
"We demonstrated that post-laser topical application of ADSC-CM in combination with niacinamide has anti-aging effect on skin."5.41Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy. ( Chung, KB; Kim, J; Kim, S; Lee, JH; Lee, YI, 2021)
" Most studies indicated that the NAD+ precursors NAM, NR, nicotinamide mononucleotide (NMN), and to a lesser extent NAD+ and NADH had a favourable outcome on several age-related disorders associated with the accumulation of chronic oxidative stress, inflammation and impaired mitochondrial function."5.05NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. ( Braidy, N; Liu, Y, 2020)
" This formulation also features niacinamide and terminalia chebula to further support the anti-aging benefits of retinol."4.12Facial Aging Improvement Case Study Using a Novel Combination of Retinol, Niacinamide, and Terminalia Chebula. ( Adams-Woodford, A; Ayres, P; Diaz, I; Giancola, G; Handler, M, 2022)
"Nicotinamide adenine dinucleotide (NAD) levels decrease during aging and are involved in age-related metabolic decline."3.83CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism. ( Camacho-Pereira, J; Chini, CCS; Chini, EN; Escande, C; Galina, A; Nin, V; Puranik, AS; Reid, JM; Schoon, RA; Tarragó, MG; Warner, GM, 2016)
"Sorafenib is the standard of care for advanced hepatocellular carcinoma (HCC)."3.81Sorafenib use in elderly patients with hepatocellular carcinoma: caution about use of platelet aggregation inhibitors. ( Boucher, E; Brunot, A; Cattenoz, C; Crouzet, L; Edeline, J; Gédouin, D; Guillygomarc'h, A; Larible, C; Latournerie, M; Le Roy, F; Le Sourd, S, 2015)
"The aim of this study was to determine whether skeletal muscle depletion predicts the prognosis of patients with hepatocellular carcinoma (HCC) that is being treated with sorafenib."3.81Skeletal muscle depletion predicts the prognosis of patients with hepatocellular carcinoma treated with sorafenib. ( Hanai, T; Ideta, T; Imai, K; Kochi, T; Miyazaki, T; Shimizu, M; Shiraki, M; Suetsugu, A; Takai, K, 2015)
"Recent onset type 1 diabetes patients (n=64, mean age 8."2.71A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX). ( Beretta Anguissola, G; Bizzarri, C; Corbi, S; Crinò, A; Manca Bitti, ML; Manfrini, S; Matteoli, MC; Mesturino, C; Patera, IP; Pitocco, D; Pozzilli, P; Schiaffini, R; Spera, S; Suraci, C; Visalli, N, 2004)
" To estimate the N-methylation ability for azaheterocyclic amines in parkinsonian patient, nicotinamide was dosed with 100 mg to 26 parkinsonians and 20 controls consisted of 16 other neurogenic disease patients and 4 healthy volunteers."2.69N-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test. ( Aoyama, K; Fukushima, S; Hayase, N; Kobayashi, S; Matsubara, K; Ohta, S; Okada, K; Satomi, M; Shimizu, K; Shiono, H; Uezono, T; Yamaguchi, S, 2000)
"Trehalose treatment reduced the activation of the UPR and inflammatory signaling, and reduced liver injury."1.46Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice. ( Estrada, AL; Hudson, WM; LaRocca, TJ; Pagliassotti, MJ; Seals, DR; Wang, D; Wei, Y; Zigler, ML, 2017)
"Nicorandil treatment resulted in an additional 0."1.35Effects of chronic treatment with a low dose of nicorandil on the function of the rat aorta during ageing. ( Faury, G; Lavanchy, N; Mecham, RP; Mezin, P; Raveaud, S; Starcher, B; Verdetti, J, 2009)
"In all hepatomas, with the exception of Morris hepatoma 5123tc, nicotinamide methylase activity was significantly decreased in comparison to normal adult rat liver."1.27Nicotinamide methylation. Tissue distribution, developmental and neoplastic changes. ( Hoshino, J; Kröger, H; Seifert, R, 1984)

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199020 (19.05)18.7374
1990's5 (4.76)18.2507
2000's23 (21.90)29.6817
2010's30 (28.57)24.3611
2020's27 (25.71)2.80

Authors

AuthorsStudies
Wei, Z1
Chai, H1
Chen, Y1
Cheng, Y1
Liu, X1
McReynolds, MR1
Chellappa, K2
Chiles, E1
Jankowski, C1
Shen, Y1
Chen, L1
Descamps, HC1
Mukherjee, S1
Bhat, YR1
Lingala, SR1
Chu, Q1
Botolin, P1
Hayat, F2
Doke, T1
Susztak, K1
Thaiss, CA1
Lu, W1
Migaud, ME4
Su, X1
Rabinowitz, JD2
Baur, JA3
Yaku, K1
Palikhe, S1
Izumi, H1
Yoshida, T1
Hikosaka, K1
Karim, M1
Iqbal, T1
Nitta, Y1
Sato, A1
Ishihara, K1
Mori, H1
Nakagawa, T1
Shariff, R1
Du, Y1
Dutta, M1
Kumar, S1
Thimmaiah, S1
Doraiswamy, C1
Kumari, A1
Kale, V1
Nair, N1
Zhang, S1
Joshi, M1
Santhanam, U1
Qiang, Q1
Damodaran, A1
Conlon, N1
Ford, D1
Pei, Z1
Wang, F1
Wang, K1
Wang, L1
Handler, M1
Adams-Woodford, A1
Ayres, P1
Giancola, G1
Diaz, I1
Cercillieux, A1
Ratajczak, J1
Joffraud, M1
Sanchez-Garcia, JL1
Jacot, G1
Zollinger, A1
Métairon, S1
Giroud-Gerbetant, J1
Rumpler, M1
Ciarlo, E1
Valera-Alberni, M1
Sambeat, A1
Canto, C1
Helman, T2
Braidy, N3
Dutta, T1
Kapoor, N1
Mathew, M1
Chakraborty, SS1
Ward, NP1
Prieto-Farigua, N1
Falzone, A1
DeLany, JP1
Smith, SR1
Coen, PM1
DeNicola, GM1
Gardell, SJ1
Nejabati, HR2
Roshangar, L1
Bazhanova, ED3
Sokolova, YO2
Teplyi, DL2
Elhassan, YS1
Kluckova, K1
Fletcher, RS1
Schmidt, MS1
Garten, A1
Doig, CL1
Cartwright, DM1
Oakey, L1
Burley, CV1
Jenkinson, N1
Wilson, M1
Lucas, SJE1
Akerman, I1
Seabright, A1
Lai, YC1
Tennant, DA1
Nightingale, P1
Wallis, GA1
Manolopoulos, KN1
Brenner, C2
Philp, A1
Lavery, GG1
Liu, Y1
Orlandi, I1
Vai, M1
Mehmel, M1
Jovanović, N1
Spitz, U1
Yang, Q1
Cong, L1
Wang, Y1
Luo, X1
Li, H1
Wang, H1
Zhu, J1
Dai, S1
Jin, H1
Yao, G1
Shi, S1
Hsueh, AJ1
Sun, Y1
Teply, DL1
Anisimov, VN2
Kang, BE1
Choi, JY1
Stein, S1
Ryu, D1
Schmeisser, K1
Shahnazi, V1
Samimifar, D1
Faridvand, Y1
Bahrami-Asl, Z1
Fathi-Maroufi, N1
Nikanfar, S1
Nouri, M1
Alyoussef, A1
Nasr, M1
Ahmed, RF1
Ahmed Farid, OAH1
Bakeer, R1
Karandikar, H1
Paradkar, A1
Bazhin, AA1
Sinisi, R1
De Marchi, U1
Hermant, A1
Sambiagio, N1
Maric, T1
Budin, G1
Goun, EA1
Lee, YI1
Kim, S1
Kim, J2
Chung, KB1
Lee, JH1
Kropotov, A1
Kulikova, V1
Nerinovski, K1
Yakimov, A1
Svetlova, M1
Solovjeva, L1
Sudnitsyna, J1
Khodorkovskiy, M1
Ziegler, M1
Nikiforov, A1
Harrison, DE1
Strong, R1
Reifsnyder, P1
Kumar, N1
Fernandez, E1
Flurkey, K1
Javors, MA1
Lopez-Cruzan, M1
Macchiarini, F1
Nelson, JF1
Markewych, A1
Bitto, A1
Sindler, AL1
Cortopassi, G1
Kavanagh, K1
Leng, L1
Bucala, R1
Rosenthal, N1
Salmon, A1
Stearns, TM1
Bogue, M1
Miller, RA1
Tannous, C1
Deloux, R1
Karoui, A1
Mougenot, N1
Burkin, D1
Blanc, J1
Coletti, D1
Lavery, G1
Li, Z1
Mericskay, M1
Sun, X1
Cao, B1
Naval-Sanchez, M1
Pham, T1
Sun, YBY1
Williams, B1
Heazlewood, SY1
Deshpande, N1
Li, J1
Kraus, F1
Rae, J1
Nguyen, Q1
Yari, H1
Schröder, J1
Heazlewood, CK1
Fulton, M1
Hatwell-Humble, J1
Das Gupta, K1
Kapetanovic, R1
Chen, X1
Sweet, MJ1
Parton, RG1
Ryan, MT1
Polo, JM1
Nefzger, CM1
Nilsson, SK1
Sun, P1
Qie, S1
Pan, B1
Hacioglu, C1
Kar, F1
Kanbak, G1
Pagliassotti, MJ1
Estrada, AL1
Hudson, WM1
Wei, Y1
Wang, D1
Seals, DR1
Zigler, ML1
LaRocca, TJ1
Pajk, M1
Cselko, A1
Varga, C1
Posa, A1
Tokodi, M1
Boldogh, I1
Goto, S1
Radak, Z1
Waltz, TB1
Fivenson, EM1
Morevati, M1
Li, C1
Becker, KG1
Bohr, VA1
Fang, EF1
Garrido, A1
Djouder, N1
Yoshino, J2
Imai, SI1
Goody, MF1
Henry, CA1
Fan, R1
Cui, J2
Ren, F1
Wang, Q1
Huang, Y1
Zhao, B1
Wei, L1
Qian, X1
Xiong, X1
Yamaguchi, S2
Hosseini, L1
Vafaee, MS1
Mahmoudi, J1
Badalzadeh, R1
Igarashi, M1
Miura, M1
Williams, E1
Jaksch, F1
Kadowaki, T1
Yamauchi, T1
Guarente, L1
Izu, H1
Shibata, S1
Fujii, T1
Matsubara, K2
Brasili, E1
Mengheri, E1
Tomassini, A1
Capuani, G1
Roselli, M1
Finamore, A1
Sciubba, F1
Marini, F1
Miccheli, A1
Ghosh, D2
LeVault, KR2
Brewer, GJ2
Zheng, M1
Qiao, W1
Liu, L2
Liu, H1
Wang, Z1
Yan, C1
Oblong, JE1
Khambati, HK1
Choueiri, TK1
Kollmannsberger, CK1
North, S1
Bjarnason, GA1
Vaishampayan, UN1
Wood, L1
Knox, JJ1
Tan, MH1
MacKenzie, MJ1
Donskov, F1
Rini, BI1
Heng, DY1
Edeline, J1
Crouzet, L1
Le Sourd, S1
Larible, C1
Brunot, A1
Le Roy, F1
Cattenoz, C1
Latournerie, M1
Gédouin, D1
Guillygomarc'h, A1
Boucher, E1
Sukhanov, DS1
Imai, K1
Takai, K1
Hanai, T1
Ideta, T1
Miyazaki, T1
Kochi, T1
Suetsugu, A1
Shiraki, M1
Shimizu, M1
Kartashova, EA1
Romantsov, MG1
Sarvilina, IV1
Zhang, T1
Zhou, Y1
Li, L1
Wang, HH1
Ma, XS1
Qian, WP1
Shen, W1
Schatten, H1
Sun, QY1
Camacho-Pereira, J1
Tarragó, MG1
Chini, CCS1
Nin, V1
Escande, C1
Warner, GM1
Puranik, AS1
Schoon, RA1
Reid, JM1
Galina, A1
Chini, EN1
Frederick, DW1
Loro, E1
Davila, A1
Silverman, IM1
Quinn, WJ1
Gosai, SJ1
Tichy, ED1
Davis, JG1
Mourkioti, F1
Gregory, BD1
Dellinger, RW1
Redpath, P1
Nakamaru-Ogiso, E1
Khurana, TS1
Kawamura, T1
Mori, N1
Shibata, K2
Dragun, P1
Makarewicz, D1
Wójcik, L1
Ziemka-Nałecz, M1
Słomka, M1
Zalewska, T1
Fukuwatari, T1
Wada, H1
Raveaud, S1
Mezin, P1
Lavanchy, N1
Starcher, B1
Mecham, RP1
Verdetti, J1
Faury, G1
Uno, Y1
Iwashita, H1
Tsukamoto, T1
Uchiyama, N1
Kawamoto, T1
Kori, M1
Nakanishi, A1
Chen, YH1
Wang, MF1
Liao, JW1
Chang, SP1
Hu, ML1
Morales, P1
Simola, N1
Bustamante, D1
Lisboa, F1
Fiedler, J1
Gebicke-Haerter, PJ1
Morelli, M1
Tasker, RA1
Herrera-Marschitz, M1
Xu, P1
Sauve, AA1
Li, Y2
He, X1
He, J1
Anderstam, B1
Andersson, G1
Lindgren, U1
Barnett, AJ1
Bitterman, KJ1
Anderson, RM1
Cohen, HY1
Latorre-Esteves, M1
Sinclair, DA3
Suarez-Pinzon, WL1
Mabley, JG1
Power, R1
Szabó, C1
Rabinovitch, A1
Strauss, E1
OERIU, S1
ROUX, JF1
GORDON, EE1
BAKER, H1
Couzin, J1
Crinò, A1
Schiaffini, R1
Manfrini, S1
Mesturino, C1
Visalli, N1
Beretta Anguissola, G1
Suraci, C1
Pitocco, D1
Spera, S1
Corbi, S1
Matteoli, MC1
Patera, IP1
Manca Bitti, ML1
Bizzarri, C1
Pozzilli, P1
Li, F1
Chong, ZZ1
Maiese, K1
Slominska, EM1
Rutkowski, P1
Smolenski, RT1
Szutowicz, A1
Rutkowski, B1
Swierczynski, J1
Morris, BJ2
Poon, HF1
Vaishnav, RA1
Butterfield, DA1
Getchell, ML1
Getchell, TV1
Denu, JM2
Yang, H1
Lavu, S1
Tsuchiya, M1
Dang, N1
Kerr, EO1
Hu, D1
Steffen, KK1
Oakes, JA1
Kennedy, BK1
Kaeberlein, M1
Belenky, P1
Bogan, KL1
Tayama, Y1
Miyake, K1
Sugihara, K1
Kitamura, S1
Kobayashi, M1
Morita, S1
Ohta, S2
Kihira, K1
Stefani, M1
Markus, MA1
Lin, RC1
Pinese, M1
Dawes, IW1
Rolig, EC1
Hook, JB1
Bond, JT1
Seifert, R1
Hoshino, J1
Kröger, H1
Horita, N1
Ishii, T1
Izumiyama, Y1
Pincheira, J1
Gallo, C1
Bravo, M1
Navarrete, MH1
Lopez-Saez, JF1
Sano, A1
Endo, N1
Takitani, S1
Köppen, A1
Klein, J1
Schmidt, BH1
van der Staay, FJ1
Löffelholz, K1
Aoyama, K1
Okada, K1
Fukushima, S1
Shimizu, K1
Uezono, T1
Satomi, M1
Hayase, N1
Shiono, H1
Kobayashi, S1
Streffer, C1
Tanigawa, Y1
Kawamura, M1
Kitamura, A1
Shimoyama, M3
Bell, JD1
Sadler, PJ1
Morris, VC1
Levander, OA1
Somogyi, A1
Siebert, D1
Bochner, F1
Morris, G1
Nadler, JV1
Nemeroff, CB1
Slotkin, TA1
Licastro, F1
Walford, RL1
Hunecke, I1
Bunge, HC1
Clerens, J1
Schlettwein-Gsell, D1
Stanulović, M1
Chaykin, S1
Wilson, JT1
Dennick, RG1
Dean, PD1
Johnson, TC1
Mathews, RA1
Chou, L1
Sapadnjuk, WI1
Kuprasch, LP1
Strishowa-Salowa, NI1
Saika, MU1
Fenshin, KM1
Oranskaja, SA1
Kawai, H1
Matsunaga, R1
Hatotani, N1
Sakamoto, H1
Takeuchi, T1
Yamaguchi, K1
Ueda, I2
Shigehisa, S1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Improved Skin Whitening Outcomes Associated With Nicotinamide Fortified Consumption in 30 to 50-Year-old Women, a Double Blind, Control and Randomized Study[NCT05696938]70 participants (Actual)Interventional2023-02-16Completed
A Randomized, Double Blind, Controlled Study of Improved Skin Anti-aging Outcomes Associated With Collagen Fortified Consumption In 30 to 50-Year-old Women[NCT05670977]70 participants (Actual)Interventional2023-01-16Completed
Center-Based and Home-Based Walking Exercise Intervention to Reduce Fatigue in Older Breast Cancer Survivors[NCT05684367]24 participants (Anticipated)Interventional2023-11-29Recruiting
Nicotinamide Riboside in Ulcerative Colitis[NCT05561738]40 participants (Anticipated)Interventional2024-01-01Not yet recruiting
Validation of an Enzymatic Assay for Quantification of Nicotinamide Adenine Dinucleotide in Blood Plasma After Ingestion of the Vitamin B3 Variant Nicotinamide Riboside: a Randomized Controlled Trial[NCT06005350]54 participants (Anticipated)Interventional2023-11-01Recruiting
Three-Day Dosing NAD + Study[NCT03707652]8 participants (Actual)Interventional2018-03-12Completed
Impact of Infant Feeding on Newborn Metabolomic Profile[NCT01606683]30 participants (Actual)Interventional2012-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

22 reviews available for niacinamide and Aging

ArticleYear
Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?
    Current opinion in pharmacology, 2021, Volume: 60

    Topics: Aging; Dietary Supplements; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide

2021
A systems-approach to NAD+ restoration.
    Biochemical pharmacology, 2022, Volume: 198

    Topics: Aging; Humans; NAD; Niacinamide; Reproducibility of Results

2022
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders.
    Drugs & aging, 2023, Volume: 40, Issue:1

    Topics: Aging; Dietary Supplements; Humans; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Monon

2023
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders.
    Drugs & aging, 2023, Volume: 40, Issue:1

    Topics: Aging; Dietary Supplements; Humans; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Monon

2023
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders.
    Drugs & aging, 2023, Volume: 40, Issue:1

    Topics: Aging; Dietary Supplements; Humans; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Monon

2023
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders.
    Drugs & aging, 2023, Volume: 40, Issue:1

    Topics: Aging; Dietary Supplements; Humans; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Monon

2023
NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis.
    Experimental gerontology, 2020, Volume: 132

    Topics: Aging; Animals; Humans; Inflammation; Mice; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinami

2020
Nicotinamide Riboside-The Current State of Research and Therapeutic Uses.
    Nutrients, 2020, May-31, Volume: 12, Issue:6

    Topics: Aging; Animals; Betacoronavirus; Biological Availability; Cardiovascular Diseases; Coronavirus Infec

2020
Implications of NAD
    European journal of clinical investigation, 2020, Volume: 50, Issue:10

    Topics: ADP-ribosyl Cyclase; Aging; Animals; Biosynthetic Pathways; Carboxy-Lyases; Clinical Trials as Topic

2020
N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin?
    Ageing research reviews, 2020, Volume: 62

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Female; Humans; Niacinamide; Polycystic Ovary Syndrom

2020
Sarcopenia, Aging and Prospective Interventional Strategies.
    Current medicinal chemistry, 2018, Volume: 25, Issue:40

    Topics: Aging; Animals; Coumarins; Humans; Mitochondria; Molecular Structure; Niacinamide; Sarcopenia; Tomat

2018
NAD
    Trends in cancer, 2017, Volume: 3, Issue:8

    Topics: Aging; Humans; Incidence; Life Expectancy; Longevity; NAD; Neoplasms; Niacinamide; Nicotinamide Mono

2017
NAD
    Cell metabolism, 2018, 03-06, Volume: 27, Issue:3

    Topics: Aging; Animals; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds

2018
A need for NAD+ in muscle development, homeostasis, and aging.
    Skeletal muscle, 2018, 03-07, Volume: 8, Issue:1

    Topics: Aging; Animals; Homeostasis; Humans; Intracellular Space; Muscle Development; Muscle Proteins; Muscl

2018
The pathophysiological importance and therapeutic potential of NAD' biosynthesis and mitochondrial sirtuin SIRT3 in age-associated diseases.
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:9

    Topics: Aging; Animals; Humans; Hydrolases; Mice; Mitochondria; Niacinamide; Protein Processing, Post-Transl

2016
Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions.
    Biogerontology, 2019, Volume: 20, Issue:4

    Topics: Aging; Drug Discovery; Humans; Ischemia; Mitochondria; NAD; Niacinamide; Nicotinamide Mononucleotide

2019
The evolving role of the NAD+/nicotinamide metabolome in skin homeostasis, cellular bioenergetics, and aging.
    DNA repair, 2014, Volume: 23

    Topics: Aging; Energy Metabolism; Glycolysis; Humans; Metabolome; NAD; Niacinamide; Oxidative Phosphorylatio

2014
Vitamin B3, the nicotinamide adenine dinucleotides and aging.
    Mechanisms of ageing and development, 2010, Volume: 131, Issue:4

    Topics: ADP Ribose Transferases; Aging; Animals; Apoptosis; Cell Cycle; Cell Physiological Phenomena; DNA Da

2010
Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide.
    Frontiers in bioscience : a journal and virtual library, 2004, Sep-01, Volume: 9

    Topics: Aging; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Caspases; Cell Survival; Endothel

2004
Toward a unified theory of caloric restriction and longevity regulation.
    Mechanisms of ageing and development, 2005, Volume: 126, Issue:9

    Topics: Aging; Animals; Caloric Restriction; Cell Survival; Cytokines; Gene Expression Regulation; Glucocort

2005
A forkhead in the road to longevity: the molecular basis of lifespan becomes clearer.
    Journal of hypertension, 2005, Volume: 23, Issue:7

    Topics: Aging; Animals; Evolution, Molecular; Flavonoids; Gene Expression Profiling; Humans; Niacinamide; Ol

2005
Vitamin B3 and sirtuin function.
    Trends in biochemical sciences, 2005, Volume: 30, Issue:9

    Topics: Aging; Apoptosis; Cell Differentiation; Humans; Niacinamide; Sirtuins; Transcription, Genetic

2005
Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity?
    Experimental gerontology, 2006, Volume: 41, Issue:8

    Topics: Aging; Animals; Caloric Restriction; Longevity; Mammals; NAD; Niacinamide; Nicotinamide Phosphoribos

2006
NAD+ metabolism in health and disease.
    Trends in biochemical sciences, 2007, Volume: 32, Issue:1

    Topics: ADP Ribose Transferases; ADP-ribosyl Cyclase; Aging; Animals; Candida glabrata; Candidiasis; Humans;

2007
Developmental pharmacology: a review of its application to clinical and basic science.
    Annual review of pharmacology, 1972, Volume: 12

    Topics: Aging; Androgens; Aniline Compounds; Animals; Estrogens; Ethanol; Female; Fetus; Fluorosis, Dental;

1972

Trials

6 trials available for niacinamide and Aging

ArticleYear
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
    International journal of cosmetic science, 2022, Volume: 44, Issue:1

    Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation

2022
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
    International journal of cosmetic science, 2022, Volume: 44, Issue:1

    Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation

2022
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
    International journal of cosmetic science, 2022, Volume: 44, Issue:1

    Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation

2022
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
    International journal of cosmetic science, 2022, Volume: 44, Issue:1

    Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation

2022
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD
    Cell reports, 2019, 08-13, Volume: 28, Issue:7

    Topics: Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents; Cross-Sectional Studies; Cytokines; Double

2019
Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy.
    Journal of cosmetic dermatology, 2021, Volume: 20, Issue:6

    Topics: Adipocytes; Aging; Humans; Laser Therapy; Mesenchymal Stem Cells; Niacinamide; Skin Aging

2021
[The study of the effectiveness of drug prevention mechanisms of cardiovascular aging by cytoflavin].
    Advances in gerontology = Uspekhi gerontologii, 2014, Volume: 27, Issue:4

    Topics: Aged; Aging; Blood Coagulation; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambu

2014
A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX).
    European journal of endocrinology, 2004, Volume: 150, Issue:5

    Topics: Adolescent; Aging; Antioxidants; C-Peptide; Child; Diabetes Mellitus, Type 1; Drug Therapy, Combinat

2004
N-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:8-9

    Topics: Aged; Aging; Aldehyde Oxidase; Aldehyde Oxidoreductases; Brain; Carbolines; Chromatography, High Pre

2000

Other Studies

77 other studies available for niacinamide and Aging

ArticleYear
NAD
    Cell systems, 2021, 12-15, Volume: 12, Issue:12

    Topics: Aging; Animals; Caloric Restriction; Mice; NAD; Niacinamide

2021
BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities.
    Nature communications, 2021, 11-19, Volume: 12, Issue:1

    Topics: A549 Cells; Administration, Oral; ADP-ribosyl Cyclase; Aging; Animals; Antigens, CD; Dietary Supplem

2021
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging.
    Mini reviews in medicinal chemistry, 2022, Volume: 22, Issue:18

    Topics: Aging; Animals; Antioxidants; Heart; Humans; Mice; NAD; Niacinamide; Ventricular Remodeling

2022
Facial Aging Improvement Case Study Using a Novel Combination of Retinol, Niacinamide, and Terminalia Chebula.
    Journal of drugs in dermatology : JDD, 2022, Jul-01, Volume: 21, Issue:7

    Topics: Aging; Humans; Niacinamide; Retinoids; Skin Aging; Terminalia; Tretinoin; Vitamin A

2022
Nicotinamide riboside kinase 1 protects against diet and age-induced pancreatic β-cell failure.
    Molecular metabolism, 2022, Volume: 66

    Topics: Aging; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose; Insulin-Secreting Cells; Mice; M

2022
Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans.
    Cell reports, 2023, 03-28, Volume: 42, Issue:3

    Topics: Aging; Animals; Cells, Cultured; Cytokines; Humans; Mice; NAD; Niacinamide; Nicotinamide Phosphoribo

2023
N1-Methylnicotinamide: The Mysterious Anti-aging Actor in Renal Transplantation.
    Current pharmaceutical design, 2023, Volume: 29, Issue:10

    Topics: Aged; Aging; Humans; Kidney; Kidney Transplantation; Niacinamide; Vitamins

2023
[Effects of cytoflavin on neuronal apoptotic processes in the murine cerebral cortex on a model of physiologicaland pathological aging].
    Arkhiv patologii, 2019, Volume: 81, Issue:4

    Topics: Aging; Animals; Apoptosis; Cerebral Cortex; Disease Models, Animal; Drug Combinations; Female; Flavi

2019
Assays for Monitoring the Effects of Nicotinamide Supplementation on Mitochondrial Activity in Saccharomyces cerevisiae.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2138

    Topics: Aging; Cell Respiration; Dietary Supplements; Membrane Potential, Mitochondrial; Mitochondria; Mitoc

2020
Increasing ovarian NAD
    Free radical biology & medicine, 2020, 08-20, Volume: 156

    Topics: Aging; Animals; Energy Metabolism; Female; Mice; Mitochondria; NAD; Niacinamide; Reactive Oxygen Spe

2020
[Cytoflavin effect on locomotor and psychoemotional status in physiological and pathological aging.]
    Advances in gerontology = Uspekhi gerontologii, 2020, Volume: 33, Issue:2

    Topics: Aging; Animals; Drug Combinations; Emotions; Flavin Mononucleotide; Inosine Diphosphate; Locomotion;

2020
Nicotinamide extrudates as novel anti-aging and collagen promoting platform: a comparative cosmeceutical study versus the gel form.
    Pharmaceutical development and technology, 2020, Volume: 25, Issue:9

    Topics: Aging; Amino Acids; Animals; Collagen; Cosmeceuticals; Drug Carriers; Drug Compounding; Female; Gels

2020
A bioluminescent probe for longitudinal monitoring of mitochondrial membrane potential.
    Nature chemical biology, 2020, Volume: 16, Issue:12

    Topics: Adipocytes; Adipose Tissue, Brown; Aging; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazon

2020
Equilibrative Nucleoside Transporters Mediate the Import of Nicotinamide Riboside and Nicotinic Acid Riboside into Human Cells.
    International journal of molecular sciences, 2021, Jan-30, Volume: 22, Issue:3

    Topics: Aging; Cytosol; Equilibrative Nucleoside Transport Proteins; HEK293 Cells; Humans; Magnetic Resonanc

2021
17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex.
    Aging cell, 2021, Volume: 20, Issue:5

    Topics: Aging; Animals; Estradiol; Female; Longevity; Male; Mice; Niacinamide; Pyridinium Compounds; Sex Cha

2021
NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging.
    International journal of molecular sciences, 2021, Mar-29, Volume: 22, Issue:7

    Topics: Aging; Animals; Cardiomegaly; Cardiomyopathy, Dilated; Cytosol; Disease Models, Animal; Electrocardi

2021
Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells.
    Nature communications, 2021, 05-11, Volume: 12, Issue:1

    Topics: Age Factors; Aging; Animals; Bone Marrow Cells; Cells, Cultured; Gene Expression Profiling; Gene Exp

2021
Nicotinamide Riboside will Play an Important Role in Anti-aging Therapy in Humans, Especially in the Face Skin Anti-aging Treatment.
    Aesthetic plastic surgery, 2022, Volume: 46, Issue:Suppl 1

    Topics: Aging; Humans; Niacinamide; Pyridinium Compounds

2022
Reproductive Effects of Nicotinamide on Testicular Function and Structure in Old Male Rats: Oxidative, Apoptotic, Hormonal, and Morphological Analyses.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:12

    Topics: Aging; Animals; Apoptosis; Dose-Response Relationship, Drug; Male; Niacinamide; Oxidative Stress; Ra

2021
Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice.
    The Journal of nutritional biochemistry, 2017, Volume: 45

    Topics: Aging; AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Biomarkers; Blood Glucose; Dietary

2017
Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats.
    Biogerontology, 2017, Volume: 18, Issue:4

    Topics: Acetylation; Age Factors; Aging; Animals; Cyclic AMP Response Element-Binding Protein; Female; Muscl

2017
Overexpression of NRK1 ameliorates diet- and age-induced hepatic steatosis and insulin resistance.
    Biochemical and biophysical research communications, 2018, 06-02, Volume: 500, Issue:2

    Topics: Aging; Animals; Diet, High-Fat; Fatty Liver; HEK293 Cells; Humans; Insulin Resistance; Lipid Metabol

2018
NAD
    Aging cell, 2019, Volume: 18, Issue:3

    Topics: Adult Stem Cells; Aging; Animals; Carbazoles; Cell Proliferation; Cells, Cultured; Dextran Sulfate;

2019
Sake cake (sake-kasu) ingestion increases branched-chain amino acids in the plasma, muscles, and brains of senescence-accelerated mice prone 8.
    Bioscience, biotechnology, and biochemistry, 2019, Volume: 83, Issue:8

    Topics: Aging; Amino Acids, Branched-Chain; Animals; Blood Glucose; Brain; Diet; Electrophoresis, Capillary;

2019
Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice.
    The Journal of nutrition, 2013, Volume: 143, Issue:10

    Topics: Age Factors; Aging; Animals; Bifidobacterium; Feces; Homocysteine; Intestines; Lactobacillus acidoph

2013
Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species.
    Neurobiology of aging, 2014, Volume: 35, Issue:1

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Disease Mo

2014
Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells.
    Molecular and cellular biochemistry, 2014, Volume: 393, Issue:1-2

    Topics: Aging; Cellular Senescence; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Huma

2014
Efficacy of targeted therapy for metastatic renal cell carcinoma in the elderly patient population.
    Clinical genitourinary cancer, 2014, Volume: 12, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antibodies, Monoclonal, Humanized; Antineoplastic Agent

2014
Sorafenib use in elderly patients with hepatocellular carcinoma: caution about use of platelet aggregation inhibitors.
    Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Agents; Asthenia; Carcinoma, Hepatocellular; Comorbid

2015
[Comparative experimental study of the influence of drugs that improve brain metabolism (angiogen, cytoflavin) on neuronal apoptosis and function of cerebral cortex during aging].
    Eksperimental'naia i klinicheskaia farmakologiia, 2015, Volume: 78, Issue:2

    Topics: Aging; Animals; Apoptosis; Aspirin; Behavior, Animal; Caspase 3; Caspase 8; Cerebral Cortex; Cogniti

2015
Skeletal muscle depletion predicts the prognosis of patients with hepatocellular carcinoma treated with sorafenib.
    International journal of molecular sciences, 2015, Apr-28, Volume: 16, Issue:5

    Topics: Aged; Aging; Carcinoma, Hepatocellular; Demography; Dose-Response Relationship, Drug; Female; Humans

2015
SIRT1, 2, 3 protect mouse oocytes from postovulatory aging.
    Aging, 2016, Volume: 8, Issue:4

    Topics: Aging; Animals; Cellular Senescence; Female; Mice; Niacinamide; Oocytes; Reactive Oxygen Species; Si

2016
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.
    Cell metabolism, 2016, 06-14, Volume: 23, Issue:6

    Topics: ADP-ribosyl Cyclase 1; Aging; Animals; Diet, High-Fat; Mammals; Mice, Inbred C57BL; Mice, Knockout;

2016
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.
    Cell metabolism, 2016, 08-09, Volume: 24, Issue:2

    Topics: Administration, Oral; Aging; Animals; Biological Availability; Energy Metabolism; Glucose; Homeostas

2016
β-Nicotinamide Mononucleotide, an Anti-Aging Candidate Compound, Is Retained in the Body for Longer than Nicotinamide in Rats.
    Journal of nutritional science and vitaminology, 2016, Volume: 62, Issue:4

    Topics: Aging; Animals; Injections, Intraperitoneal; Longevity; Male; NAD; Niacinamide; Nicotinamide Mononuc

2016
Matrix metaloproteinases activity during the evolution of hypoxic-ischemic brain damage in the immature rat. The effect of 1-methylnicotinamide (MNA).
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59, Issue:3

    Topics: Aging; Animals; Anti-Inflammatory Agents; Brain; Brain Chemistry; Electrophoresis, Polyacrylamide Ge

2008
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
    Journal of nutritional science and vitaminology, 2008, Volume: 54, Issue:5

    Topics: Age Factors; Aging; Animals; Biotin; Body Weight; Eating; Folic Acid; Liver; Male; Models, Animal; N

2008
Effects of chronic treatment with a low dose of nicorandil on the function of the rat aorta during ageing.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:10

    Topics: Aging; Animals; Antihypertensive Agents; Aorta; Biomechanical Phenomena; Collagen; Dose-Response Rel

2009
Efficacy of a novel, orally active GSK-3 inhibitor 6-Methyl-N-[3-[[3-(1-methylethoxy)propyl]carbamoyl]-1H-pyrazol-4-yl]pyridine-3-carboxamide in tau transgenic mice.
    Brain research, 2009, Nov-03, Volume: 1296

    Topics: Administration, Oral; Aging; Animals; Brain; Cold Temperature; Dose-Response Relationship, Drug; Enz

2009
Beneficial effects of nicotinamide on alcohol-induced liver injury in senescence-accelerated mice.
    BioFactors (Oxford, England), 2008, Volume: 34, Issue:2

    Topics: Aging; Alanine Transaminase; Animals; Catalase; Disease Models, Animal; Ethanol; Glutathione Peroxid

2008
Nicotinamide prevents the long-term effects of perinatal asphyxia on apoptosis, non-spatial working memory and anxiety in rats.
    Experimental brain research, 2010, Volume: 202, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Anxiety; Apoptosis; Asphyxia Neonatorum; Behavior, Animal; Female;

2010
Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: a possible cause for reduced osteogenesis and increased adipogenesis in older individuals.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:11

    Topics: Adipocytes; Adipogenesis; Aging; Animals; Bone Marrow Cells; Carbazoles; Cell Line; Cell Lineage; Cu

2011
A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Apr-25, Volume: 32, Issue:17

    Topics: Adenine Nucleotides; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Calcium; Cel

2012
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1.
    The Journal of biological chemistry, 2002, Nov-22, Volume: 277, Issue:47

    Topics: Aging; DNA, Ribosomal; Gene Silencing; Genes, Fungal; Green Fluorescent Proteins; Histone Deacetylas

2002
Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes.
    Diabetes, 2003, Volume: 52, Issue:7

    Topics: Aging; Animals; Apoptosis; Diabetes Mellitus, Type 1; Enzyme Inhibitors; Interferon-gamma; Interleuk

2003
Hungering for simplicity.
    Science of aging knowledge environment : SAGE KE, 2003, May-14, Volume: 2003, Issue:19

    Topics: Aging; Caloric Restriction; Histone Deacetylases; NAD; Niacinamide; Saccharomyces cerevisiae; Silent

2003
[Research on the relation between vitamin coenzymes and corresponding enzymes in relation to the age of the animal and under the influence of certain substances proper to the organism].
    Biokhimiia (Moscow, Russia), 1963, Volume: 28

    Topics: Acetylesterase; Adenine Nucleotides; Aging; Alanine Transaminase; Amino Acids; Animals; Aspartate Am

1963
CONTENT AND SYNTHESIS OF HEPATIC PYRIDINE NUCLEOTIDES IN FETAL AND NEONATAL RABBITS.
    The American journal of physiology, 1965, Volume: 209

    Topics: Aging; Animals; DNA; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; Metabolism; NAD; NADP; N

1965
Scientific community. Aging research's family feud.
    Science (New York, N.Y.), 2004, Feb-27, Volume: 303, Issue:5662

    Topics: Aging; Animals; Australia; Biotechnology; Caloric Restriction; Histone Deacetylases; History, 20th C

2004
The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma.
    Molecular and cellular biochemistry, 2004, Volume: 267, Issue:1-2

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aging; Animals; Blood Urea Nitrogen; C

2004
Proteomic identification of differentially expressed proteins in the aging murine olfactory system and transcriptional analysis of the associated genes.
    Journal of neurochemistry, 2005, Volume: 94, Issue:2

    Topics: Age Factors; Aging; Animals; Diagnostic Imaging; Electrophoresis, Gel, Two-Dimensional; Gene Express

2005
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.
    Aging cell, 2006, Volume: 5, Issue:6

    Topics: Acetylation; Aging; Caloric Restriction; Cell Division; Cellular Senescence; Food Deprivation; Histo

2006
Developmental changes of aldehyde oxidase activity in young Japanese children.
    Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:4

    Topics: Aging; Aldehyde Oxidase; Body Surface Area; Child; Child, Preschool; Female; Humans; Infant; Liver;

2007
Vitamins and aging: pathways to NAD+ synthesis.
    Cell, 2007, May-04, Volume: 129, Issue:3

    Topics: Aging; Animals; Histone Deacetylases; Humans; Longevity; NAD; Niacinamide; Pyridinium Compounds; Sac

2007
The effect of resveratrol on a cell model of human aging.
    Annals of the New York Academy of Sciences, 2007, Volume: 1114

    Topics: Aging; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p16; Fibroblasts; Forkhead Box Pr

2007
In vitro renal transport functions of the progeny of rats with streptozotocin-induced diabetes.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 170, Issue:2

    Topics: Aging; Aminoisobutyric Acids; Animals; Biological Transport; Diabetes Mellitus, Experimental; Female

1982
Nicotinamide methylation. Tissue distribution, developmental and neoplastic changes.
    Biochimica et biophysica acta, 1984, Sep-28, Volume: 801, Issue:2

    Topics: Aging; Animals; Brain; Carcinoma, Ehrlich Tumor; Cell Line; Female; Kidney; Liver; Liver Neoplasms,

1984
Ultrastructure of 6-aminonicotinamide (6-AN)-induced lesions in the central nervous system of rats. II. Alterations of the nervous susceptibility with aging.
    Acta neuropathologica, 1980, Volume: 49, Issue:1

    Topics: 6-Aminonicotinamide; Aging; Animals; Brain Stem; Central Nervous System; Central Nervous System Dise

1980
G2 repair and aging: influence of donor age on chromosomal aberrations in human lymphocytes.
    Mutation research, 1993, Volume: 295, Issue:2

    Topics: Adenosine; Adult; Aged; Aging; Caffeine; Cell Cycle; Child, Preschool; Chromosome Aberrations; DNA R

1993
Fluorometric assay of rat brain N-methyltransferase with 4-methylnicotinamide.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:3

    Topics: Aging; Animals; Brain; Chromatography, High Pressure Liquid; Enzyme Stability; Female; Kinetics; Mal

1993
Effects of nicotinamide on central cholinergic transmission and on spatial learning in rats.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:4

    Topics: Acetylcholine; Aging; Animals; Brain Chemistry; Choline; Cognition; Extracellular Space; Hippocampus

1996
The contribution of tryptophan to the regulation of the NAD+ level in mouse liver.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: Aging; Animals; Liver; Mice; NAD; Niacinamide; Nicotinic Acids; Organ Specificity; Tryptophan

1975
Suppression and stimulation of DNA synthesis by ADP-ribosylation of nuclear proteins from adult hen and chick embryo liver.
    Biochemical and biophysical research communications, 1978, Apr-28, Volume: 81, Issue:4

    Topics: Aging; Animals; Cell Nucleus; Chick Embryo; Chickens; DNA; Female; Liver; NAD; Niacinamide; Nucleosi

1978
Effect of aging and diet on proton NMR spectra of rat urine.
    Magnetic resonance in medicine, 1991, Volume: 17, Issue:2

    Topics: Aging; Animals; Caseins; Citrates; Citric Acid; Creatinine; Diet; Glycoproteins; Hippurates; Hydroge

1991
Determination of endogenous concentrations of N1-methylnicotinamide in human plasma and urine by high-performance liquid chromatography.
    Analytical biochemistry, 1990, May-15, Volume: 187, Issue:1

    Topics: Acetophenones; Adolescent; Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Fluores

1990
Effects of neonatal treatment with 6-aminonicotinamide on basal and isoproterenol-stimulated ornithine decarboxylase activity in cerebellum of the development rat.
    Biochemical pharmacology, 1985, Sep-15, Volume: 34, Issue:18

    Topics: 6-Aminonicotinamide; Aging; Animals; Animals, Newborn; Body Weight; Cerebellum; Enzyme Activation; I

1985
Modulatory effect of nicotinamide on unscheduled DNA synthesis in lymphocytes from young and old mice.
    Mechanisms of ageing and development, 1986, Volume: 35, Issue:2

    Topics: Aging; Animals; Cell Survival; Cells, Cultured; Concanavalin A; DNA Replication; Hydroxyurea; Lympho

1986
[Behavior of blood lipid fraction under Turigeran].
    Zeitschrift fur Alternsforschung, 1970, Volume: 23, Issue:2

    Topics: Aged; Aging; Aminobenzoates; Ascorbic Acid; Cholesterol; Female; Humans; Lipid Metabolism; Lipids; M

1970
[Problem in psychogeriatrics: quantitative and qualitative cerebral circulation insufficiencies in geriatric medicine].
    Zeitschrift fur Alternsforschung, 1971, Volume: 24, Issue:1

    Topics: Aged; Aging; Cerebrovascular Disorders; Dietary Proteins; Glucose; Hemodynamics; Humans; Infections;

1971
[Changes in the nutrition of single women after the age of 70].
    Gerontologia, 1968, Volume: 14, Issue:4

    Topics: Aged; Aging; Ascorbic Acid; Carotenoids; Feeding Behavior; Female; Fruit; Humans; Iron; Niacinamide;

1968
Aldehyde oxidase: catalysis of the oxidation of N 1 -methylnicotinamide and pyridoxal.
    Archives of biochemistry and biophysics, 1971, Volume: 145, Issue:1

    Topics: Aging; Aldehydes; Alleles; Ammonium Sulfate; Animals; Carbon Isotopes; Catalysis; Chemical Precipita

1971
Squalene-2(3)-epoxide-lanosterol cyclase in developing rat brain.
    Journal of neurochemistry, 1974, Volume: 23, Issue:1

    Topics: Aging; Animals; Brain; Cell-Free System; Deoxycholic Acid; Ethers, Cyclic; Imidazoles; Isomerases; K

1974
tRNA methyltransferase activity in neonatal and mature mammalian neural tissue.
    Journal of neurochemistry, 1974, Volume: 23, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Centrifugation, Density Gradient; Cyt

1974
[Pharmacodynamic effect of complex polyvitamin drugs on old animals].
    Zeitschrift fur Alternsforschung, 1974, Volume: 28, Issue:3

    Topics: Aging; Animals; Ascorbic Acid; Drug Combinations; Flavonoids; Methionine; Niacinamide; Rabbits; Rats

1974
[Characteristics of NAD metabolism in the brain--with reference to a comparison with the liver].
    Shinkei kenkyu no shimpo. Advances in neurological sciences, 1966, Volume: 10, Issue:2

    Topics: Aging; Animals; Brain; Carbon Tetrachloride Poisoning; Chlorpromazine; Liver; Male; NAD; Niacinamide

1966
The biosynthesis and degradation of nicotinamide-adenine dinucleotide during cick embryonic development.
    Biochimica et biophysica acta, 1969, Jun-17, Volume: 184, Issue:1

    Topics: Aging; Animals; Carbon Isotopes; Chick Embryo; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinic Ac

1969
Nicotinamide adenine dinucleotide in developing chick embryo.
    Biochimica et biophysica acta, 1971, May-18, Volume: 237, Issue:2

    Topics: Aging; Alcohol Oxidoreductases; Animals; Chick Embryo; Egg White; Egg Yolk; Female; Hydrogen-Ion Con

1971