niacinamide has been researched along with Acute Brain Injuries in 23 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These data suggest that administration of NMN at a proper dosage has a strong protective effect against ischemic brain injury." | 5.43 | Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia. ( Kristian, T; Long, A; Owens, K; Park, JH, 2016) |
| "4%) patients treated with cytoflavin in dosage 20-40 ml daily intravenously in drops during 10 days in addition to standard treatment." | 2.78 | [Correction of energy homeostasis in the acute period of concomitant brain injury]. ( Beletskiĭ, AV; Nikonov, VV; Pavlenko, AIu, 2013) |
| " These data suggest that administration of NMN at a proper dosage has a strong protective effect against ischemic brain injury." | 1.43 | Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia. ( Kristian, T; Long, A; Owens, K; Park, JH, 2016) |
| "Previous research has demonstrated considerable preclinical efficacy of nicotinamide (NAM; vitamin B(3)) in animal models of TBI with systemic dosing at 50 and 500 mg/kg yielding improvements on sensory, motor, cognitive and histological measures." | 1.37 | Continuous nicotinamide administration improves behavioral recovery and reduces lesion size following bilateral frontal controlled cortical impact injury. ( Anderson, GD; Hoane, MR; Vonder Haar, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, D | 1 |
| Jia, S | 1 |
| Li, T | 1 |
| Li, D | 1 |
| Wang, X | 1 |
| Liu, X | 1 |
| Wang, YF | 1 |
| Savvina, IA | 1 |
| Cherebillo, VY | 1 |
| Zabrodskaya, YM | 1 |
| Petrova, AO | 1 |
| Sergeev, AV | 1 |
| Paltsev, AA | 1 |
| Rutkovskiy, RV | 1 |
| Malkhozova, AM | 1 |
| Nikonov, VV | 1 |
| Pavlenko, AIu | 1 |
| Beletskiĭ, AV | 1 |
| Vonder Haar, C | 2 |
| Maass, WR | 1 |
| Jacobs, EA | 1 |
| Hoane, MR | 12 |
| Lebedeva, EA | 1 |
| Kurtasov, AA | 1 |
| Belousova, ME | 1 |
| Nemkova, ZA | 1 |
| Kaminskiĭ, MIu | 1 |
| Popov, RV | 1 |
| Trofimovich, SL | 1 |
| Peterson, TC | 2 |
| McConomy, KS | 1 |
| Farin, FM | 1 |
| Bammler, TK | 1 |
| MacDonald, JW | 1 |
| Kantor, ED | 2 |
| Anderson, GD | 5 |
| Park, JH | 1 |
| Long, A | 1 |
| Owens, K | 1 |
| Kristian, T | 1 |
| Pierce, JL | 3 |
| Holland, MA | 3 |
| Quigley, A | 1 |
| Tan, AA | 3 |
| Skoromets, AA | 1 |
| Pugacheva, EL | 1 |
| Swan, AA | 1 |
| Chandrashekar, R | 1 |
| Beare, J | 1 |
| Sung, JH | 1 |
| Kim, MO | 1 |
| Koh, PO | 1 |
| Batotsyrenova, KhV | 1 |
| Livanov, GA | 1 |
| Shestova, GV | 1 |
| Sizova, KV | 1 |
| Velikova, VD | 1 |
| Akstulewicz, SL | 1 |
| Toppen, J | 1 |
| Gilbert, DR | 1 |
| Smith, DC | 2 |
| Kaplan, SA | 1 |
| Ellis, AL | 1 |
| Kamada, K | 1 |
| Houkin, K | 1 |
| Iwasaki, Y | 1 |
| Abe, H | 1 |
| Yamanaka, K | 1 |
| Kumura, E | 1 |
| Yoshimine, T | 1 |
| Maruno, M | 1 |
| Taniguchi, M | 1 |
| Kosaka, H | 1 |
| Hayakawa, T | 1 |
| Vajragupta, O | 1 |
| Toasaksiri, S | 1 |
| Boonyarat, C | 1 |
| Wongkrajang, Y | 1 |
| Peungvicha, P | 1 |
| Watanabe, H | 1 |
| Boonchoong, P | 1 |
3 trials available for niacinamide and Acute Brain Injuries
| Article | Year |
|---|---|
[Correction of energy homeostasis in the acute period of concomitant brain injury].
Topics: Adolescent; Adult; Brain Injuries; Critical Care; Drug Combinations; Energy Metabolism; Female; Flav | 2013 |
[Clinical effectiveness of cytoflavin inclusion in intensive care of patients with combined traumatic brain injury].
Topics: Adolescent; Adult; Aged; Brain Injuries; Critical Care; Drug Combinations; Female; Flavin Mononucleo | 2014 |
[Efficacy of the complex drug cytoflavin in the treatment of consequences of mild brain injury].
Topics: Adolescent; Adult; Brain Injuries; Drug Combinations; Flavin Mononucleotide; gamma-Aminobutyric Acid | 2010 |
20 other studies available for niacinamide and Acute Brain Injuries
| Article | Year |
|---|---|
Alleviation of brain injury by applying TGN-020 in the supraoptic nucleus via inhibiting vasopressin neurons in rats of focal ischemic stroke.
Topics: Animals; Brain Injuries; Ischemic Stroke; Male; Microinjections; Neurons; Niacinamide; Rats; Rats, W | 2021 |
[The intraoperative prophylaxis of local ischemical brain damage in neurosurgical patients with cerebral aneurysm].
Topics: Brain; Brain Injuries; Brain Ischemia; Drug Combinations; Flavin Mononucleotide; Humans; Inosine Dip | 2019 |
Deficits in discrimination after experimental frontal brain injury are mediated by motivation and can be improved by nicotinamide administration.
Topics: Animals; Brain Injuries; Cognition; Discrimination Learning; Discrimination, Psychological; Frontal | 2014 |
A Combination Therapy of Nicotinamide and Progesterone Improves Functional Recovery following Traumatic Brain Injury.
Topics: Animals; Brain Injuries; Drug Therapy, Combination; Male; Niacinamide; Progesterone; Rats; Rats, Spr | 2015 |
Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia.
Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Disease Models, Animal; Hippocampus; Male; Mice | 2016 |
Nicotinamide treatment induces behavioral recovery when administered up to 4 hours following cortical contusion injury in the rat.
Topics: Animals; Behavior, Animal; Brain; Brain Injuries; Memory; Niacinamide; Rats; Rats, Sprague-Dawley; T | 2008 |
The effects of hypertonic saline and nicotinamide on sensorimotor and cognitive function following cortical contusion injury in the rat.
Topics: Animals; Behavior, Animal; Brain; Brain Injuries; Central Nervous System Agents; Cognition; Locomoti | 2009 |
Preclinical efficacy testing in middle-aged rats: nicotinamide, a novel neuroprotectant, demonstrates diminished preclinical efficacy after controlled cortical impact.
Topics: Age Factors; Analysis of Variance; Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Inju | 2011 |
Continuous nicotinamide administration improves behavioral recovery and reduces lesion size following bilateral frontal controlled cortical impact injury.
Topics: Animals; Behavior, Animal; Brain Injuries; Cognition; Data Interpretation, Statistical; Frontal Lobe | 2011 |
Nicotinamide prevents the down-regulation of MEK/ERK/p90RSK signaling cascade in brain ischemic injury.
Topics: Animals; Brain Injuries; Brain Ischemia; Cerebral Infarction; Down-Regulation; Extracellular Signal- | 2012 |
A comparison of the effects of nicotinamide and progesterone on functional recovery of cognitive behavior following cortical contusion injury in the rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Brain Injuries; Cognition; Hippocampus; Infu | 2012 |
[Using cytoflavin for prophylaxis and treatment of cognitive amnestic disorders in patients with heavy toxicohypoxic damage of brain].
Topics: Adult; Brain Injuries; Cognition Disorders; Drug Combinations; Female; Flavin Mononucleotide; Humans | 2012 |
Treatment with vitamin B3 improves functional recovery and reduces GFAP expression following traumatic brain injury in rats.
Topics: Animals; Astrocytes; Brain Injuries; Cognition; Disease Models, Animal; Glial Fibrillary Acidic Prot | 2003 |
Nicotinamide reduces acute cortical neuronal death and edema in the traumatically injured brain.
Topics: Animals; Brain Injuries; Cerebral Cortex; Edema; Male; Neuroprotective Agents; Niacinamide; Rats; Ra | 2006 |
Nicotinamide treatment reduces behavioral impairments and provides cortical protection after fluid percussion injury in the rat.
Topics: Animals; Brain Injuries; Cognition; Disease Models, Animal; Dose-Response Relationship, Drug; Mental | 2006 |
The effects of nicotinamide on apoptosis and blood-brain barrier breakdown following traumatic brain injury.
Topics: Analysis of Variance; Animals; Apoptosis; Blood-Brain Barrier; Brain Injuries; Disease Models, Anima | 2006 |
Nicotinamide treatment provides acute neuroprotection and GFAP regulation following fluid percussion injury.
Topics: Animals; Astrocytes; Behavior, Animal; Brain Chemistry; Brain Injuries; Cell Count; Cerebral Cortex; | 2008 |
A high-field magnetic resonance imaging study of experimental vasogenic brain edema and its response to AVS: 1,2-bis (nicotinamido)-propane.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cerebral Cortex; Corpus Cal | 1994 |
Cellular expression of inducible nitric oxide synthase following rat cortical incision and its suppression by hydroxyl radical scavenger, 1,2-bis(nicotinamido)propane.
Topics: Animals; Antibodies; Brain Injuries; Cerebral Cortex; Free Radical Scavengers; Hydroxyl Radical; Mac | 1998 |
Chroman amide and nicotinyl amide derivatives: inhibition of lipid peroxidation and protection against head trauma.
Topics: Animals; Brain Injuries; Chromans; Craniocerebral Trauma; Disease Models, Animal; Dopamine; Electron | 2000 |