Page last updated: 2024-10-19

niacinamide and Acoustic Trauma

niacinamide has been researched along with Acoustic Trauma in 5 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Acoustic Trauma: Usually refer to hearing loss due to a single noise event such as an explosion or shotgun blast.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Han, S1
Du, Z1
Liu, K1
Gong, S1
Brenner, C1
Brown, KD1
Maqsood, S1
Huang, JY1
Pan, Y1
Harkcom, W1
Li, W1
Sauve, A1
Verdin, E1
Jaffrey, SR1
Tabuchi, K1
Hoshino, T1
Murashita, H1
Oikawa, K1
Uemaetomari, I1
Nishimura, B1
Tobita, T1
Hara, A1
Lehmann, A1
Simler, S1
Mandel, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study to Evaluate the Effect of Nicotinamide Riboside on Immunity[NCT02812238]38 participants (Actual)Interventional2016-06-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean IL-1 Beta Release From Peripheral Blood Mononuclear Cells During Refeeding After 24 Hour Fast

The IL- 1beta secretion is measured in response to fasting, refeeding and administration of Nicotinamide Riboside (or placebo). Nicotinamide riboside acts as a fasting mimetic, and is supposed to maintain the reduction of IL-1 beta secretion (indicating NLRP3 inflammasome activation) induced by fasting. 1000 mg of Nicotinamide riboside on a daily basis is given to the subjects for a period of 7-10 days. (NCT02812238)
Timeframe: 4 weeks

Interventionmg/dL (Mean)
Nicotinamide Riboside582
Placebo794

Other Studies

5 other studies available for niacinamide and Acoustic Trauma

ArticleYear
Nicotinamide riboside protects noise-induced hearing loss by recovering the hair cell ribbon synapses.
    Neuroscience letters, 2020, 04-23, Volume: 725

    Topics: Acoustic Stimulation; Animals; Hair Cells, Auditory, Inner; Hearing Loss, Noise-Induced; Male; Mice;

2020
Boosting NAD to spare hearing.
    Cell metabolism, 2014, Dec-02, Volume: 20, Issue:6

    Topics: Animals; Female; Hearing Loss, Noise-Induced; Male; NAD; Niacinamide; Sirtuin 3

2014
Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss.
    Cell metabolism, 2014, Dec-02, Volume: 20, Issue:6

    Topics: Animals; Female; Hearing Loss, Noise-Induced; Male; Mice; NAD; Niacinamide; Pyridinium Compounds; Si

2014
Involvement of poly(ADP-ribose) synthetase in acoustic trauma of the cochlea.
    The Tohoku journal of experimental medicine, 2003, Volume: 200, Issue:4

    Topics: Acoustic Stimulation; Action Potentials; Aminobenzoates; Animals; Benzamides; Cochlea; Enzyme Activa

2003
[Protection against audiogenic crises in mice by nicotinamide].
    Journal de physiologie, 1967, Volume: 59, Issue:4 Suppl

    Topics: Age Factors; Aminobutyrates; Animals; Coenzymes; Hearing Loss, Noise-Induced; Hydrazines; Mice; NAD;

1967