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niacin and Xeroderma Pigmentosum

niacin has been researched along with Xeroderma Pigmentosum in 4 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Xeroderma Pigmentosum: A rare, pigmentary, and atrophic autosomal recessive disease. It is manifested as an extreme photosensitivity to ULTRAVIOLET RAYS as the result of a deficiency in the enzyme that permits excisional repair of ultraviolet-damaged DNA.

Research Excerpts

ExcerptRelevanceReference
"An extremely rare pellagra-like condition has been described, which was partially responsive to niacin and associated with a multisystem involvement."7.81Pellagra-like condition is xeroderma pigmentosum/Cockayne syndrome complex and niacin confers clinical benefit. ( Alkuraya, FS; Ansari, S; Hamad, MH; Hassan, HH; Hijazi, H; Ibrahim, N; Karrar, ZA; Mohamed, KA; Mukhtar, MM; Salih, MA; Salih, SB, 2015)
"An extremely rare pellagra-like condition has been described, which was partially responsive to niacin and associated with a multisystem involvement."3.81Pellagra-like condition is xeroderma pigmentosum/Cockayne syndrome complex and niacin confers clinical benefit. ( Alkuraya, FS; Ansari, S; Hamad, MH; Hassan, HH; Hijazi, H; Ibrahim, N; Karrar, ZA; Mohamed, KA; Mukhtar, MM; Salih, MA; Salih, SB, 2015)
"In exogenous photosensitization, the chemical agent (chromophore) is most often identified, reaching the skin either via topical contact or by systemic administration (drugs)."2.37[Photosensitivity in human pathology: mechanisms and clinical aspects]. ( Jeanmougin, M, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hijazi, H1
Salih, MA1
Hamad, MH1
Hassan, HH1
Salih, SB1
Mohamed, KA1
Mukhtar, MM1
Karrar, ZA1
Ansari, S1
Ibrahim, N1
Alkuraya, FS1
Hanno, R1
Owen, LG1
Callen, JP1
Jeanmougin, M1
Bligard, CA1
Storer, JS1

Reviews

1 review available for niacin and Xeroderma Pigmentosum

ArticleYear
[Photosensitivity in human pathology: mechanisms and clinical aspects].
    Biochimie, 1986, Volume: 68, Issue:6

    Topics: Adult; DNA; Female; Furocoumarins; Humans; Lupus Erythematosus, Systemic; Pellagra; Photochemistry;

1986

Other Studies

3 other studies available for niacin and Xeroderma Pigmentosum

ArticleYear
Pellagra-like condition is xeroderma pigmentosum/Cockayne syndrome complex and niacin confers clinical benefit.
    Clinical genetics, 2015, Volume: 87, Issue:1

    Topics: Base Sequence; Child, Preschool; Cockayne Syndrome; Comet Assay; DNA Damage; DNA-Binding Proteins; E

2015
Sunlight and the skin.
    Primary care, 1978, Volume: 5, Issue:4

    Topics: Adult; Female; Humans; Hydroa Vacciniforme; Lupus Erythematosus, Systemic; Male; Middle Aged; Pellag

1978
Photosensitivity in infants and children.
    Dermatologic clinics, 1986, Volume: 4, Issue:2

    Topics: Bloom Syndrome; Child; Child, Preschool; Cockayne Syndrome; Female; Hartnup Disease; Humans; Hydroa

1986