Page last updated: 2024-10-19

niacin and Weight Gain

niacin has been researched along with Weight Gain in 37 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"Fatty liver is caused when rats are given orotic acid of the pyrimidine base in large quantities."7.81Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats. ( Fukuwatari, T; Kawamura, T; Morita, N; Shibata, K; Tsuji, A, 2015)
"We investigated the change of tryptophan-niacin metabolism in rats with puromycin aminonucleoside PAN-induced nephrosis, the mechanisms responsible for their change of urinary excretion of nicotinamide and its metabolites, and the role of the kidney in tryptophan-niacin conversion."7.73Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis. ( Egashira, Y; Nagaki, S; Sanada, H, 2006)
"Niacin treatment did not affect the percentages of N retained/N absorbed, N retained/N intake, DE, or ME."5.38Effect of graded levels of niacin supplementation of a semipurified diet on energy and nitrogen balance, growth performance, diarrhea occurrence, and niacin metabolite excretion by growing swine. ( Ivers, DJ; Veum, TL, 2012)
"Fatty liver is caused when rats are given orotic acid of the pyrimidine base in large quantities."3.81Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats. ( Fukuwatari, T; Kawamura, T; Morita, N; Shibata, K; Tsuji, A, 2015)
"Ecological evidence suggests that niacin (nicotinamide and nicotinic acid) fortification may be involved in the increased prevalence of obesity and type 2 diabetes, both of which are associated with insulin resistance and epigenetic changes."3.79Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats. ( Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS, 2013)
" The nutraceutical GEA, ALA, niacin, and NA completely prevented the SFA-induced disturbances of BBB and normalized the measures of neurovascular inflammation and oxidative stress."3.79Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood-brain barrier function in wild-type mice. ( Giles, C; Lam, V; Mamo, JC; Pallebage-Gamarallage, MM; Takechi, R, 2013)
"To determine the tolerable upper intake level of nicotinic acid in humans, we investigated the effects of excess nicotinic acid administration on body weight gain, food intake, and urinary excretion of water-soluble vitamins and the metabolism of tryptophan in weaning rats."3.75[Effects of excess nicotinic acid on growth and the urinary excretion of B-group vitamins and the metabolism of tryptophan in weaning rats]. ( Fukuwatari, T; Kurata, K; Shibata, K, 2009)
"We investigated the change of tryptophan-niacin metabolism in rats with puromycin aminonucleoside PAN-induced nephrosis, the mechanisms responsible for their change of urinary excretion of nicotinamide and its metabolites, and the role of the kidney in tryptophan-niacin conversion."3.73Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis. ( Egashira, Y; Nagaki, S; Sanada, H, 2006)
"0% of DM) or the supply of various N-sources (urea, rape seed meal, soya bean meal, fish meal) were investigated on rumen fermentation, blood parameters, feed intake, weight gain and dry matter (DM) intake per weight gain in three individual feeding experiments with 156 growing bulls weighing between 175 and 300 kg per animal."3.68[The influence of oral niacin doses during different dietary protein levels on indexes of rumen fermentation, blood parameters and fattening performance of young bulls]. ( Flachowsky, G; Schneider, M; Wilk, H; Wolfram, D, 1993)
" In the presence of excess dietary nicotinamide, chicks fed the corn-casein diet achieved maximal weight gain when 100 mg/kg of L-tryptophan was supplemented."3.68Quantitative efficacy of niacin sources for chicks: nicotinic acid, nicotinamide, NAD and tryptophan. ( Baker, DH; Oduho, GW, 1993)
"Niacin treatment did not affect the percentages of N retained/N absorbed, N retained/N intake, DE, or ME."1.38Effect of graded levels of niacin supplementation of a semipurified diet on energy and nitrogen balance, growth performance, diarrhea occurrence, and niacin metabolite excretion by growing swine. ( Ivers, DJ; Veum, TL, 2012)
"Body weight gain was significantly improved by L-carnitine, or L-carnitine + niacin supplementation during the first 3 weeks."1.32Effects of L-carnitine and niacin supplied by drinking water on fattening performance, carcass quality and plasma L-carnitine concentration of broiler chicks. ( Canacankatan, N; Celik, L; Inal, TC; Kayrin, L; Oztürkcan, O, 2003)
" As the result, the urinary excretion of Nam, N1-methyl-4-pyridone-3-carboxamide (4-Py), Nam + N1-methylnicotinamide (MNA) + N1-methyl-2-pyridone-5-carboxamide (2-Py) + 4-Py was lower in the CCl4-treated groups than in the non-treated group (control) regardless of the experimental period (1 mo and 2 mo) or dosing amount of CCl4 (0."1.30Tryptophan-niacin metabolism in liver cirrhosis rat caused by carbon tetrachloride. ( Egashira, Y; Isagawa, A; Komine, T; Ohta, T; Sanada, H; Shibata, K; Yamada, E, 1999)
"Niacin was added at 0, 3, 9, 27, or 81 ppm to a low-protein test (LPT) diet fortified with crystalline amino acids and at 0 or 81 ppm to a positive control (PC) diet."1.29Effect of niacin additions to corn-soybean meal diets on performance of pigs from weaning to finishing. ( Ivers, DJ; Veum, TL, 1993)
"A niacin deficiency was established in weanling rats with diets containing 1."1.29Poly(ADP-ribose) polymerase activity and DNA strand breaks are affected in tissues of niacin-deficient rats. ( Henning, SM; Swendseid, ME; Zhang, JZ, 1993)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.11)18.7374
1990's17 (45.95)18.2507
2000's11 (29.73)29.6817
2010's5 (13.51)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Asadi, N1
Izadi, M1
Aflatounian, A1
Esmaeili-Dehaj, M1
Rezvani, ME1
Hafizi, Z1
Takemoto, S1
Funaba, M1
Matsui, T1
Li, D1
Tian, YJ1
Guo, J1
Sun, WP1
Lun, YZ1
Guo, M1
Luo, N1
Cao, Y1
Cao, JM1
Gong, XJ1
Zhou, SS1
Takechi, R1
Pallebage-Gamarallage, MM1
Lam, V1
Giles, C1
Mamo, JC1
Shibata, K11
Morita, N1
Kawamura, T1
Tsuji, A1
Fukuwatari, T7
Kurata, K1
Ivers, DJ2
Veum, TL2
Morikawa, Y1
Sugimoto, E3
Celik, L1
Oztürkcan, O1
Inal, TC1
Canacankatan, N1
Kayrin, L1
BARNARD, RD1
GIACALONE, O1
MONACO, P1
MUDIE, IS1
HORNE, NW1
CROFTON, JW1
Kimura, N1
Sasaki, R2
Takahashi, C1
Egashira, Y3
Nagaki, S1
Sanada, H3
Augspurger, NR1
Baker, DH2
Thorn, SL1
Young, GS1
Kirkland, JB1
Flachowsky, G1
Wolfram, D1
Wilk, H1
Schneider, M1
Matthews, PG1
Wahlqvist, ML1
Marks, SJ1
Myers, KA1
Hodgson, JM1
Oduho, GW1
Zhang, JZ1
Henning, SM3
Swendseid, ME3
Leibetseder, J1
Mushiage, M1
Kondo, T3
Hayakawa, T1
Tsuge, H1
Marugami, M1
Umezawa, C1
Shimada, H1
Kegley, EB1
Spears, JW1
Eisemann, JH1
Zhang, J1
Heber, D1
Choi, J1
Wang, Y1
Go, VL1
Ivandic, BT1
Liao, F1
Tanabe, A1
Ohta, T2
Isagawa, A1
Komine, T1
Yamada, E1
Basu, TK1
Makhani, N1
Sedgwick, G1
Harms, RH2
Bootwalla, SM1
Johnson, NE1
Harland, BF1
Ross, E1
Gautz, L1
Dunn, MA1
Ruiz, N1

Trials

1 trial available for niacin and Weight Gain

ArticleYear
Excess dietary lysine increases growth of chicks fed niacin-deficient diets, but dietary quinolinic acid has no niacin-sparing activity.
    Poultry science, 2007, Volume: 86, Issue:2

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplement

2007

Other Studies

36 other studies available for niacin and Weight Gain

ArticleYear
Chronic niacin administration ameliorates ovulation, histological changes in the ovary and adiponectin concentrations in a rat model of polycystic ovary syndrome.
    Reproduction, fertility, and development, 2021, Volume: 33, Issue:7

    Topics: Adiponectin; Administration, Oral; Animals; Disease Models, Animal; Female; Niacin; Organ Size; Ovar

2021
Effect of niacin supplementation in long-distance transported steer calves.
    Animal science journal = Nihon chikusan Gakkaiho, 2018, Volume: 89, Issue:10

    Topics: Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Body Weight; Cattle; Diet; Dieta

2018
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
    The British journal of nutrition, 2013, Volume: 110, Issue:12

    Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epige

2013
Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood-brain barrier function in wild-type mice.
    Journal of neuroinflammation, 2013, Jun-19, Volume: 10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins A; Blood-Brain Barrier; Cyclooxyge

2013
Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats.
    Journal of nutritional science and vitaminology, 2015, Volume: 61, Issue:5

    Topics: Animals; Biotin; Fatty Liver; Folic Acid; Liver; Male; Niacin; Orotic Acid; Pantothenic Acid; Rats;

2015
[Effects of excess nicotinic acid on growth and the urinary excretion of B-group vitamins and the metabolism of tryptophan in weaning rats].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2009, Volume: 50, Issue:2

    Topics: Animals; Eating; Growth; Male; Niacin; Quinolinic Acid; Rats; Rats, Wistar; Reference Values; Seroto

2009
Effect of graded levels of niacin supplementation of a semipurified diet on energy and nitrogen balance, growth performance, diarrhea occurrence, and niacin metabolite excretion by growing swine.
    Journal of animal science, 2012, Volume: 90, Issue:1

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chromatography, High Pressure Liqu

2012
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:6

    Topics: Animals; Diet; Fats; Fatty Liver; Feeding Behavior; Liver; Male; NAD; NADP; Niacin; Organ Size; Orot

2002
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:7

    Topics: Animals; Antitubercular Agents; Carboxy-Lyases; Diet; Eating; Injections, Intraperitoneal; Kidney; K

2002
Effects of L-carnitine and niacin supplied by drinking water on fattening performance, carcass quality and plasma L-carnitine concentration of broiler chicks.
    Archiv fur Tierernahrung, 2003, Volume: 57, Issue:2

    Topics: Abdomen; Adipose Tissue; Animal Feed; Animals; Body Composition; Carnitine; Chickens; Dose-Response

2003
Weight gain during isonicotinyl hydrazide therapy.
    New York state journal of medicine, 1952, Nov-01, Volume: 52, Issue:21

    Topics: Body Weight; Body Weights and Measures; Humans; Niacin; Nicotinic Acids; Weight Gain

1952
[Effect of vitamins B6, PP and B12 on growth and weight increase after return to feeding following fasting].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:8

    Topics: Fasting; Niacin; Nicotinic Acids; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins; Weight Gai

1953
Isoniazid and weight gain: a pilot investigation.
    British medical journal, 1954, Jun-05, Volume: 1, Issue:4874

    Topics: Body Weight; Isoniazid; Niacin; Nicotinic Acids; Tuberculosis; Tuberculosis, Pulmonary; Weight Gain

1954
The necessity of niacin in rats fed on a high protein diet.
    Bioscience, biotechnology, and biochemistry, 2005, Volume: 69, Issue:2

    Topics: Animals; Caseins; Diet; Dose-Response Relationship, Drug; Niacin; Nutritional Requirements; Rats; Vi

2005
Effects of excess pantothenic acid administration on the other water-soluble vitamin metabolisms in rats.
    Journal of nutritional science and vitaminology, 2005, Volume: 51, Issue:6

    Topics: Animals; Ascorbic Acid; Diet; Eating; Energy Metabolism; Liver; Male; Niacin; Niacinamide; Organ Siz

2005
Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2006, Volume: 76, Issue:1

    Topics: Animals; Carboxy-Lyases; Kidney; Liver; Male; NAD; Nephrosis; Niacin; Niacinamide; Puromycin Aminonu

2006
The guinea-pig is a poor animal model for studies of niacin deficiency and presents challenges in any study using purified diets.
    The British journal of nutrition, 2007, Volume: 98, Issue:1

    Topics: Animals; Bone Marrow; Caseins; Dietary Supplements; Disease Models, Animal; Gelatin; Guinea Pigs; Hu

2007
[The influence of oral niacin doses during different dietary protein levels on indexes of rumen fermentation, blood parameters and fattening performance of young bulls].
    Archiv fur Tierernahrung, 1993, Volume: 45, Issue:2

    Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animal Feed; Animals; Blood Glucose; Calcium; Cattle; D

1993
Improvement in arterial stiffness during hypolipidaemic therapy is offset by weight gain.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1993, Volume: 17, Issue:10

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Arteries; Blood Pressure; Body Mass Index; Caroti

1993
Quantitative efficacy of niacin sources for chicks: nicotinic acid, nicotinamide, NAD and tryptophan.
    The Journal of nutrition, 1993, Volume: 123, Issue:12

    Topics: Analysis of Variance; Animal Feed; Animals; Biological Assay; Chickens; Dose-Response Relationship,

1993
Effect of niacin additions to corn-soybean meal diets on performance of pigs from weaning to finishing.
    Journal of animal science, 1993, Volume: 71, Issue:12

    Topics: Animal Feed; Animals; Dietary Proteins; Eating; Female; Glycine max; Hair; Lameness, Animal; Male; N

1993
Poly(ADP-ribose) polymerase activity and DNA strand breaks are affected in tissues of niacin-deficient rats.
    The Journal of nutrition, 1993, Volume: 123, Issue:8

    Topics: Animals; Body Weight; DNA Damage; Eating; Liver; Lung; Lymphocytes; Male; Muscles; NAD; Niacin; Poly

1993
[Effects of L-carnitine in poultry].
    Archiv fur Tierernahrung, 1995, Volume: 48, Issue:1-2

    Topics: Animal Feed; Animals; Body Weight; Carnitine; Chickens; Cholesterol; Digestion; Egg Yolk; Female; Fo

1995
Effects of vitamin B6 deficiency on the conversion ratio of tryptophan to niacin.
    Bioscience, biotechnology, and biochemistry, 1995, Volume: 59, Issue:11

    Topics: Animals; Diet; Feeding Behavior; Kynurenic Acid; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan

1995
Increased conversion ratio of tryptophan to niacin by the administration of clofibrate, a hypolipidemic drug, to rats.
    Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:9

    Topics: Animals; Clofibrate; Hypolipidemic Agents; Liver; Male; NAD; Niacin; Niacinamide; Rats; Rats, Wistar

1996
Effects of feeding tryptophan-limiting diets on the conversion ratio of tryptophan to niacin in rats.
    Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:10

    Topics: Amino Acids; Animals; Caseins; Diet; Eating; Gelatin; Liver; Male; Niacin; Niacinamide; Rats; Rats,

1996
Performance and glucose metabolism in calves fed a chromium-nicotinic acid complex or chromium chloride.
    Journal of dairy science, 1997, Volume: 80, Issue:8

    Topics: Animal Feed; Animals; Blood Glucose; Cattle; Chlorides; Chromium; Chromium Compounds; Diet; Insulin;

1997
NADPH-cytochrome P-450 reductase, cytochrome P-450 2C11 and P-450 1A1, and the aryl hydrocarbon receptor in livers of rats fed methyl-folate-deficient diets.
    Nutrition and cancer, 1997, Volume: 28, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Choline Deficiency; Cytochrome P-450 CYP1

1997
Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets.
    Free radical biology & medicine, 1997, Volume: 23, Issue:6

    Topics: Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Heme O

1997
Dietary linoleic acid alters alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of niacin synthesis from tryptophan, in the process of protein expression in rat liver.
    Journal of nutritional science and vitaminology, 1998, Volume: 44, Issue:1

    Topics: Animals; Carboxy-Lyases; Dietary Fats; Dietary Fats, Unsaturated; Electrophoresis, Gel, Two-Dimensio

1998
Tryptophan-niacin metabolism in liver cirrhosis rat caused by carbon tetrachloride.
    Journal of nutritional science and vitaminology, 1999, Volume: 45, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Liver Cirrhosis, E

1999
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:6

    Topics: Animals; Antitubercular Agents; Diet; Eating; Liver; Male; NAD; NADP; Niacin; Pyrazinamide; Quinolin

2001
Niacin (nicotinic acid) in non-physiological doses causes hyperhomocysteineaemia in Sprague-Dawley rats.
    The British journal of nutrition, 2002, Volume: 87, Issue:2

    Topics: Animals; Dietary Supplements; Dose-Response Relationship, Drug; Eating; Hyperhomocysteinemia; Liver;

2002
Research note: performance of single comb White Leghorn pullets as influenced by niacin supplementation from zero to six weeks of age and subsequent layer performance.
    Poultry science, 1992, Volume: 71, Issue:4

    Topics: Animal Feed; Animals; Chickens; Eating; Female; Niacin; Oviposition; Weight Gain

1992
Effects of dietary aluminum and niacin on chick tibiae.
    Poultry science, 1992, Volume: 71, Issue:7

    Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Analysis of Variance; Animals; Bone Density; Chicke

1992
The lack of response of broiler chickens to supplemental niacin when fed a corn-soybean meal diet from 3 to 7 weeks of age.
    Poultry science, 1990, Volume: 69, Issue:12

    Topics: Animal Feed; Animals; Chickens; Eating; Female; Glycine max; Male; Niacin; Weight Gain; Zea mays

1990