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niacin and Thrombopenia

niacin has been researched along with Thrombopenia in 10 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Research Excerpts

ExcerptRelevanceReference
" However, niacin can cause flushing and niacinamide probably cause thrombocytopenia."4.90Benefits and harm of niacin and its analog for renal dialysis patients: a systematic review and meta-analysis. ( Feng, L; He, YM; Huo, DM; Liao, YH; Yang, ZH, 2014)
" Finally, assessment of CFU-MK and human platelet bioenergetics and function show that NAMPTi was toxic to MK and not platelets, which is consistent with the clinically observed time-course of thrombocytopenia."1.42Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid. ( Clarke, E; Dambach, D; Dhawan, P; Diaz, D; DosSantos, G; Dragovich, PS; Kauss, A; La, N; Lin, T; McCray, B; Misner, DL; Nguyen, T; Sampath, D; Singh, J; Tarrant, JM; Uppal, H; Zabka, TS, 2015)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's2 (20.00)18.2507
2000's1 (10.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, YM1
Feng, L1
Huo, DM1
Yang, ZH1
Liao, YH1
Tarrant, JM1
Dhawan, P1
Singh, J1
Zabka, TS1
Clarke, E1
DosSantos, G1
Dragovich, PS1
Sampath, D1
Lin, T1
McCray, B1
La, N1
Nguyen, T1
Kauss, A1
Dambach, D1
Misner, DL1
Diaz, D1
Uppal, H1
O'Connell, C1
Horwood, K1
Nadamuni, M1
BAART DE LA FAILLE, RL1
VERLOOP, MC1
KROBER, KH1
CARDINALI, G1
MAJ, A1
MUELLER, HC1
Sampathkumar, K1
Sooraj, YS1
Ajeshkumar, RP1
Reimund, E1
Ramos, A1
O'Brien, T1
Silverberg, JD1
Nguyen, TT1

Reviews

2 reviews available for niacin and Thrombopenia

ArticleYear
Benefits and harm of niacin and its analog for renal dialysis patients: a systematic review and meta-analysis.
    International urology and nephrology, 2014, Volume: 46, Issue:2

    Topics: Flushing; Humans; Lipoproteins, HDL; Niacin; Niacinamide; Phosphorus; Randomized Controlled Trials a

2014
Niacin-induced hepatitis and thrombocytopenia after 10 years of niacin use.
    Journal of clinical gastroenterology, 1994, Volume: 18, Issue:3

    Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Male; Niacin; Thrombocytopenia; Time Factors

1994

Other Studies

8 other studies available for niacin and Thrombopenia

ArticleYear
Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Agents; Blood Platelets; Cells, Cultured; Colony-Forming Units Assay; Dietar

2015
Correction of refractory thrombocytopenia and anemia following withdrawal of extended release niacin.
    American journal of hematology, 2016, Volume: 91, Issue:7

    Topics: Aged; Anemia; Delayed-Action Preparations; Erythrocyte Indices; Female; Humans; Hypolipidemic Agents

2016
[A case of thrombopenic during administration of isonicotinic acid hydrazide (nidaton)].
    Nederlands tijdschrift voor geneeskunde, 1953, Feb-28, Volume: 97, Issue:9

    Topics: Isoniazid; Niacin; Nicotinic Acids; Purpura; Purpura, Thrombocytopenic; Thrombocytopenia

1953
Purpura Haemorrhagica as a by-Product of INH Medication.
    Der Tuberkulosearzt, 1955, Volume: 9, Issue:7

    Topics: Humans; Niacin; Nicotinic Acids; Purpura; Purpura, Thrombocytopenic; Thrombocytopenia

1955
[Hemorrhagic thrombopenia caused by isoniazid].
    Minerva medica, 1955, Sep-05, Volume: 46, Issue:71

    Topics: Humans; Isoniazid; Niacin; Nicotinic Acids; Purpura; Purpura, Thrombocytopenic; Thrombocytopenia; Tu

1955
[Werlhof's disease in isonicotinic acid hydrazide therapy].
    Zeitschrift fur Tuberkulose, 1955, Volume: 106, Issue:4-5

    Topics: Isomerism; Isoniazid; Niacin; Nicotinic Acids; Purpura; Purpura, Thrombocytopenic; Purpura, Thromboc

1955
Extended release nicotinic acid is a promising agent for phosphate control in hemodialysis.
    Kidney international, 2006, Volume: 69, Issue:7

    Topics: Humans; Niacin; Phosphates; Renal Dialysis; Thrombocytopenia

2006
Nicotinic acid-induced toxicity associated with cytopenia and decreased levels of thyroxine-binding globulin.
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:5

    Topics: Aged; Aspartate Aminotransferases; Drug Therapy, Combination; Female; Humans; Hypothyroidism; Leukop

1992