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niacin and Porphyrias

niacin has been researched along with Porphyrias in 32 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.

Research Excerpts

ExcerptRelevanceReference
"In exogenous photosensitization, the chemical agent (chromophore) is most often identified, reaching the skin either via topical contact or by systemic administration (drugs)."2.37[Photosensitivity in human pathology: mechanisms and clinical aspects]. ( Jeanmougin, M, 1986)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199029 (90.63)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (9.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
THIERS, H1
ILIN, II1
BELUKHA, UK1
KNOX, JM1
Maas, RP1
Voets, PJ1
Kluger, N1
Cribier, B1
Halioua, B1
Khandpur, S1
Porter, RM1
Boulton, SJ1
Anstey, A1
Jausion, H1
GOUGEROT, L1
SAMITZ, MH1
FREEMAN, RG2
UEDA, H1
TAKEUCHI, J1
KAMEDA, H1
MATSUYAMA, K1
DANIELS, F1
PALIARD, F1
PLAUCHU, M1
BERTOYE, A1
EXBRAYAT, C1
Cormia, FE1
Binford, RT1
Jancar, J1
Herndon, JH1
Hanno, R1
Owen, LG1
Callen, JP1
Kansky, A2
Peyron, JL1
Meynadier, J1
Jeanmougin, M1
Landman, L1
Naschitz, JE1
Yeshurun, D1
Bligard, CA1
Storer, JS1
Howard, FM1
Badawy, AA1
Evans, M1
Park, RG1
Calandra, P3
Harber, LC1
Baer, RL1
Gregorc, J1
Binazzi, M2

Reviews

5 reviews available for niacin and Porphyrias

ArticleYear
Drug-induced photosensitivity: new insights into pathomechanisms and clinical variation through basic and applied science.
    The British journal of dermatology, 2017, Volume: 176, Issue:4

    Topics: Apoptosis; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Early Diagnosis; Humans; Hyperpigmenta

2017
Human disease associated with exposure to light.
    Annual review of medicine, 1976, Volume: 27

    Topics: Aged; Dermatitis; DNA Repair; Drug Eruptions; Humans; Light; Lupus Erythematosus, Discoid; Lupus Ery

1976
The pharmacological basis for the treatment of photodermatoses.
    Biochimie, 1986, Volume: 68, Issue:6

    Topics: Antigens; Antimalarials; beta Carotene; Carotenoids; DNA; Female; Humans; Immunosuppression Therapy;

1986
[Photosensitivity in human pathology: mechanisms and clinical aspects].
    Biochimie, 1986, Volume: 68, Issue:6

    Topics: Adult; DNA; Female; Furocoumarins; Humans; Lupus Erythematosus, Systemic; Pellagra; Photochemistry;

1986
Pathogenic mechanisms of drug-induced photosensitivity.
    The Journal of investigative dermatology, 1972, Volume: 58, Issue:6

    Topics: Animals; Cell Membrane; Dermatitis, Contact; Drug Hypersensitivity; Energy Transfer; Environmental E

1972

Other Studies

27 other studies available for niacin and Porphyrias

ArticleYear
[Syndrome of ecchymoses of effort without urticaria; porphyrinuria, improvement with large doses of nicotinamide].
    Lyon medical, 1952, Jul-13, Volume: 187, Issue:28

    Topics: Ecchymosis; Humans; Niacin; Niacinamide; Nicotinic Acids; Porphyrias; Syndrome; Urticaria

1952
[THE TREATMENT OF PORPHYRIA CUTANEA TARDA].
    Vestnik dermatologii i venerologii, 1963, Volume: 37

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Bloodletting; Calcium; Chlorides; Desensitizat

1963
[THERAPEUTIC EFFECTIVENESS OF SOME DRUG SUBSTANCES AND THE CONTENT OF WATER-SOLUBLE VITAMINS IN PATIENTS WITH PHOTODERMATOSES].
    Meditsinskii zhurnal Uzbekistana, 1964, Volume: 2

    Topics: Chloroquine; Eczema; Humans; Niacin; Nicotinic Acids; Photosensitivity Disorders; Porphyrias; Prurig

1964
PHOTOSENSITIVITY--A COMMON PHYSICAL ALLERGY.
    Southern medical journal, 1964, Volume: 57

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Anti-Bacterial Agents; Antimalarials; Chlorothiazide; Chlorprop

1964
The vampire in medical perspective: myth or malady?
    QJM : monthly journal of the Association of Physicians, 2014, Volume: 107, Issue:11

    Topics: Humans; Medicine in Literature; Mythology; Pellagra; Porphyrias; Rabies; Superstitions

2014
[Vampirism and medicine].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:11

    Topics: Bites, Human; Blood; Europe; Folklore; History of Medicine; History, 16th Century; History, 17th Cen

2014
[Pellagra and porphyria].
    Revue de pathologie generale et de physiologie clinique, 1956, Volume: 56, Issue:683

    Topics: Humans; Pellagra; Porphyrias; Skin Diseases; Sunlight

1956
[Dyschromia caused by photo-sensitization; with the exclusion of porphyria & pellagra].
    La Revue du praticien, 1957, Nov-01, Volume: 7, Issue:28

    Topics: Dermatitis; Humans; Pellagra; Pigmentation; Porphyrias; Skin Diseases; Sunlight

1957
SKIN MANIFESTATIONS OF GASTROINTESTINAL DISEASES. I.
    Skin, 1963, Volume: 2

    Topics: Celiac Disease; Colitis; Colitis, Ulcerative; Dermatology; Gastroenterology; Gastrointestinal Diseas

1963
THE PROBLEM OF PHOTOSENSITIVITY.
    Medical times, 1964, Volume: 92

    Topics: Carcinogens; Coloring Agents; Dermatitis; Humans; Lupus Erythematosus, Discoid; Pellagra; Pharmaceut

1964
[CASE OF BERIBERI, PELLAGRA, LIVER CIRRHOSIS AND PORPHYRINURIA IN A YOUNG MAN].
    Naika. Internal medicine, 1964, Volume: 14

    Topics: Antifibrinolytic Agents; Beriberi; Humans; Liver Cirrhosis; Male; Pathology; Pellagra; Physiology; P

1964
DISEASES CAUSED OR AGGRAVATED BY SUNLIGHT.
    The Medical clinics of North America, 1965, Volume: 49

    Topics: Collagen Diseases; Diagnosis; Drug Hypersensitivity; Drug Therapy; Dwarfism; Hartnup Disease; Herpes

1965
[Anatomoclinical observation of a pellagroid syndrome with porphyrinuria associated with polyneuritis and hepatic cirrhosis].
    Lyon medical, 1950, Oct-29, Volume: 183, Issue:44

    Topics: Humans; Liver Cirrhosis; Neuritis; Pellagra; Polyneuropathies; Porphyrias; Porphyrins

1950
Vesiculobullous eruptions associated with internal disease.
    Postgraduate medicine, 1967, Volume: 41, Issue:5

    Topics: Blister; Humans; Pellagra; Porphyrias; Virus Diseases

1967
Neurocutaneous disorder and mental functioning. The Blake March Lecture for 1974, delivered before the Royal College of Psychiatrists, 4 February 1974.
    The British journal of psychiatry : the journal of mental science, 1975, Volume: 126

    Topics: Acne Vulgaris; Adolescent; Adult; Aged; Central Nervous System Diseases; Child; Child, Preschool; Ch

1975
Sunlight and the skin.
    Primary care, 1978, Volume: 5, Issue:4

    Topics: Adult; Female; Humans; Hydroa Vacciniforme; Lupus Erythematosus, Systemic; Male; Middle Aged; Pellag

1978
Fluorescence microscopy test in porphyrias, photodermatoses and lead exposed persons.
    Archiv fur dermatologische Forschung, 1975, Jul-18, Volume: 252, Issue:4

    Topics: Anemia, Hypochromic; Environmental Exposure; Erythrocytes; Erythropoiesis; Heterozygote; Humans; Lea

1975
[Combined pellagra, porphyria variegata and chronic alcoholism].
    Harefuah, 1986, Dec-01, Volume: 111, Issue:11

    Topics: Alcoholism; Diagnosis, Differential; Humans; Male; Middle Aged; Pellagra; Porphyrias; Skin Diseases

1986
Photosensitivity in infants and children.
    Dermatologic clinics, 1986, Volume: 4, Issue:2

    Topics: Bloom Syndrome; Child; Child, Preschool; Cockayne Syndrome; Female; Hartnup Disease; Humans; Hydroa

1986
Peripheral neuropathy as a sign of systemic disease.
    Postgraduate medicine, 1971, Volume: 50, Issue:3

    Topics: Alcoholism; Anemia, Pernicious; Arsenic Poisoning; Beriberi; Blood Protein Disorders; Cholesterol; D

1971
Alcohol addiction, porphyria, and mental disorders.
    Lancet (London, England), 1972, Aug-19, Volume: 2, Issue:7773

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain Chemistry; Ethanol; Humans; Liver; Mental Disorde

1972
The age distribution of common skin disorders in the Bantu of Pretoria, Transvaal.
    The British journal of dermatology, 1968, Volume: 80, Issue:11

    Topics: Acne Vulgaris; Adolescent; Adult; Age Factors; Aged; Black or African American; Black People; Child;

1968
Tryptophan-niacin pathway in the human epidermis.
    Acta vitaminologica et enzymologica, 1974, Volume: 28, Issue:5

    Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratoacanthoma; Male; Middle

1974
Tryptophan metabolism in man, rat and pig. Determination of tryptophan-pyrrolase and kinureninase in liver.
    Acta vitaminologica et enzymologica, 1972, Volume: 26, Issue:5

    Topics: Adult; Animals; Dicarboxylic Acids; Erythema; Female; Humans; Hydrolases; Kynurenine; Lichen Planus;

1972
[Significance of the quantitative determination of porphyrins in erythrocytes].
    Acta medica Iugoslavica, 1974, Volume: 28, Issue:2

    Topics: Adult; Anemia, Hypochromic; Erythrocytes; Female; Humans; Male; Pellagra; Porphyrias; Porphyrins

1974
[Pathogenesis of photodermatosis].
    Minerva medica, 1972, Apr-11, Volume: 63, Issue:27

    Topics: Dermatitis; Humans; Lupus Erythematosus, Systemic; Metabolism, Inborn Errors; Nicotinic Acids; Pella

1972
Identification of an error in the tryptophan--niacin pathway in carriers of some dermatoses conditioned or aggravated by sunlight.
    Archiv fur klinische und experimentelle Dermatologie, 1971, Volume: 239, Issue:4

    Topics: Adult; Aged; Animals; Atrophy; Cataract; Female; Gastric Juice; Humans; Hydrolases; Kynurenine; Ligh

1971