Page last updated: 2024-10-19

niacin and Pain

niacin has been researched along with Pain in 20 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Two 65-year-old white men with coronary heart disease, given niacin therapy for dyslipidemia for 5 months, developed intense dental and gingival pain that was associated with increases in dose and that was relieved with discontinuance of niacin treatment."7.70Dental and gingival pain as side effects of niacin therapy. ( Davis, WJ; Gordon, NF; Leighton, RF; Small, GS; Ward, ES, 1998)
"Two 65-year-old white men with coronary heart disease, given niacin therapy for dyslipidemia for 5 months, developed intense dental and gingival pain that was associated with increases in dose and that was relieved with discontinuance of niacin treatment."3.70Dental and gingival pain as side effects of niacin therapy. ( Davis, WJ; Gordon, NF; Leighton, RF; Small, GS; Ward, ES, 1998)
"There is a spectrum of opioid abuse ranging from those who misuse the drug by not following doctor's orders to those who take the drugs to achieve a high or divert the drugs to the street market for profit."2.46Opioid formulations designed to resist/deter abuse. ( Pergolizzi, JV; Raffa, RB, 2010)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199010 (50.00)18.7374
1990's1 (5.00)18.2507
2000's1 (5.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Garrido-Suárez, BB1
Garrido, G1
Castro-Labrada, M1
Merino, N1
Valdés, O1
Pardo, Z1
Ochoa-Rodríguez, E1
Verdecia-Reyes, Y1
Delgado-Hernández, R1
Godoy-Figueiredo, J1
Ferreira, SH1
Lee, R1
PELNER, L1
Raffa, RB1
Pergolizzi, JV1
Lee, T1
Kamerath, JH1
De Luigi, AJ1
Arcinegas-Rodriguez, S1
Gaspers, MG1
Lowe, MC1
Godin, AM1
Ferreira, WC1
Rocha, LT1
Ferreira, RG1
Paiva, AL1
Merlo, LA1
Nascimento, EB1
Bastos, LF1
Coelho, MM1
BIANCHI, M1
NICK, J1
KRAUSE, HJ2
KRUGER, EH1
MICHEL, D1
MCNICOL, GP1
DOUGLAS, AS1
SCHMITZ, W1
Leighton, RF1
Gordon, NF1
Small, GS1
Davis, WJ1
Ward, ES1
Litin, SC1
Anderson, CF1
Kapoor, R1
Saint, S1
Kapoor, JR1
Johnson, RA1
Dhaliwal, G1
Khandpur, S1
Porter, RM1
Boulton, SJ1
Anstey, A1

Reviews

2 reviews available for niacin and Pain

ArticleYear
Opioid formulations designed to resist/deter abuse.
    Drugs, 2010, Sep-10, Volume: 70, Issue:13

    Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Combinations; Humans; Morphine; Naltrexone; Ni

2010
Drug-induced photosensitivity: new insights into pathomechanisms and clinical variation through basic and applied science.
    The British journal of dermatology, 2017, Volume: 176, Issue:4

    Topics: Apoptosis; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Early Diagnosis; Humans; Hyperpigmenta

2017

Other Studies

18 other studies available for niacin and Pain

ArticleYear
Anti-hypernociceptive and anti-inflammatory effects of JM-20: A novel hybrid neuroprotective compound.
    Brain research bulletin, 2020, Volume: 165

    Topics: Animals; Behavior, Animal; Benzodiazepines; Cell Movement; Inflammation; Male; Neuroprotective Agent

2020
Ask the doctor. Many nights I wake up once, twice, or several times with leg cramps. The only medications I take are a statin, niacin, Plavix, and baby aspirin. Are any of them causing these aggravating cramps?
    Harvard heart letter : from Harvard Medical School, 2008, Volume: 18, Issue:9

    Topics: Anticholesteremic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agen

2008
The treatment of lightning and girdle pains in tabes dorsalis with niacin.
    New York state journal of medicine, 1947, Jul-01, Volume: 47, Issue:13

    Topics: Lightning; Niacin; Nicotinic Acids; Pain; Tabes Dorsalis

1947
Ask the doctor. I have tried all of the statin drugs to lower my cholesterol, but each one has caused severe muscle pain. Are there any non-statin medications I could try using to lower my cholesterol?
    Harvard heart letter : from Harvard Medical School, 2010, Volume: 20, Issue:12

    Topics: Allylamine; Azetidines; Colesevelam Hydrochloride; Diet, Mediterranean; Ezetimibe; Humans; Hydroxyme

2010
Analgesic benefit of niacin for shrapnel wound pain in war veteran.
    Military medicine, 2010, Volume: 175, Issue:11

    Topics: Aged, 80 and over; Analgesia; Blast Injuries; Cicatrix, Hypertrophic; Humans; Hyperlipidemias; Hypol

2010
Metabolic acidosis, hypoglycemia, and severe myalgias: an attempt to mask urine drug screen results.
    Pediatric emergency care, 2011, Volume: 27, Issue:4

    Topics: Acidosis; Adolescent; Humans; Hypoglycemia; Male; Muscular Diseases; Niacin; Pain; Severity of Illne

2011
Nicotinic acid induces antinociceptive and anti-inflammatory effects in different experimental models.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; E

2012
[Therapy of pain in gynecology, with special reference to dysmenorrhea, by means of a new preparation in association with N-(1,2-diphenyl)-ethylnicotinamide].
    Quaderni di clinica ostetrica e ginecologica, 1953, Volume: 8, Issue:2

    Topics: Biphenyl Compounds; Dysmenorrhea; Female; Gynecology; Humans; Niacin; Niacinamide; Pain

1953
[Phenomenon of perseveration of painful and thermal sensations in toxic polyneuritis caused by isoniazid].
    Revue neurologique, 1955, Volume: 93, Issue:5

    Topics: Isoniazid; Nervous System Diseases; Neuritis; Niacin; Nicotinic Acids; Pain

1955
[Lowering of pain and shortening of the birth process with causat].
    Munchener medizinische Wochenschrift (1950), 1956, Sep-07, Volume: 98, Issue:36

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Atropine; Female; Humans; Labor, Obstetric; Niacin;

1956
[Lowering of pain and shortening of the birth process with causat].
    Munchener medizinische Wochenschrift (1950), 1956, Sep-07, Volume: 98, Issue:36

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Atropine; Female; Humans; Labor, Obstetric; Niacin;

1956
[Lowering of pain and shortening of the birth process with causat].
    Munchener medizinische Wochenschrift (1950), 1956, Sep-07, Volume: 98, Issue:36

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Atropine; Female; Humans; Labor, Obstetric; Niacin;

1956
[Lowering of pain and shortening of the birth process with causat].
    Munchener medizinische Wochenschrift (1950), 1956, Sep-07, Volume: 98, Issue:36

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Atropine; Female; Humans; Labor, Obstetric; Niacin;

1956
[Labor relief in obstetrical practice].
    Medizinische Klinik, 1958, Oct-24, Volume: 53, Issue:43

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Atropine; Humans; Niacin; Nicotinic Acids; Pain; Pa

1958
[Prevention of cicatricial pain].
    Therapie der Gegenwart, 1959, Volume: 98, Issue:1

    Topics: Heparin; Humans; Niacin; Nicotinic Acids; Pain; Thorax

1959
STUDIES WITH COMPLAMIN, A NICOTINIC-ACID-THEOPHYLLINE ESTER, AS A FIBRINOLYTIC AGENT.
    British medical journal, 1965, May-01, Volume: 1, Issue:5443

    Topics: Drug Therapy; Fibrinolysis; Fibrinolytic Agents; Humans; Hypotension; Injections, Intravenous; Niaci

1965
[Use of isoniazid in therapy of painful colitis of the ileocecal region].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1955, Volume: 44, Issue:3

    Topics: Colitis; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pain

1955
[On the local treatment of vertebrogenous pain states].
    Therapie der Gegenwart, 1960, Volume: 99

    Topics: Aesculus; Disease; Flavonoids; Niacin; Nicotinic Acids; Nutrition Therapy; Pain; Spinal Diseases; Sp

1960
Dental and gingival pain as side effects of niacin therapy.
    Chest, 1998, Volume: 114, Issue:5

    Topics: Aged; Gingiva; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Niacin; Pain; Toothache

1998
Nicotinic acid-associated myopathy: a report of three cases.
    The American journal of medicine, 1989, Volume: 86, Issue:4

    Topics: Female; Humans; Leg; Male; Middle Aged; Muscle Cramp; Muscular Diseases; Niacin; Pain

1989
Clinical problem-solving. D is for delay.
    The New England journal of medicine, 2014, Dec-04, Volume: 371, Issue:23

    Topics: Clostridioides difficile; Clostridium Infections; Delayed Diagnosis; Dementia; Dermatitis; Diagnosis

2014