niacin and Nausea
niacin has been researched along with Nausea in 9 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " To increase the probability of flushing, subjects were administered niacin ER at the upper limit of the approved dosage range (2,000 mg), and were precluded from using aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) during the study." | 9.12 | Improved control of niacin-induced flushing using an optimized once-daily, extended-release niacin formulation. ( Cefali, EA; Shamp, TR; Simmons, PD; Stanek, EJ, 2006) |
| "Although niacin's mechanisms of action have not been substantiated from controlled clinical trials, this agent may have beneficial effects upon migraine and tension-type headaches." | 8.82 | The treatment of migraines and tension-type headaches with intravenous and oral niacin (nicotinic acid): systematic review of the literature. ( Prousky, J; Seely, D, 2005) |
| "Niacin deficiency causes pellagra, the symptoms of which include dermatitis, diarrhoea and dementia." | 8.12 | Effect of niacin supplementation on nausea-like behaviour in an isoniazid-induced mouse model of pellagra. ( Ishikawa, T; Kuroita, T; Kuronuma, K; Natsumi, S; Yoshioka, T, 2022) |
| " To increase the probability of flushing, subjects were administered niacin ER at the upper limit of the approved dosage range (2,000 mg), and were precluded from using aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) during the study." | 5.12 | Improved control of niacin-induced flushing using an optimized once-daily, extended-release niacin formulation. ( Cefali, EA; Shamp, TR; Simmons, PD; Stanek, EJ, 2006) |
| "Although niacin's mechanisms of action have not been substantiated from controlled clinical trials, this agent may have beneficial effects upon migraine and tension-type headaches." | 4.82 | The treatment of migraines and tension-type headaches with intravenous and oral niacin (nicotinic acid): systematic review of the literature. ( Prousky, J; Seely, D, 2005) |
| "Niacin deficiency causes pellagra, the symptoms of which include dermatitis, diarrhoea and dementia." | 4.12 | Effect of niacin supplementation on nausea-like behaviour in an isoniazid-induced mouse model of pellagra. ( Ishikawa, T; Kuroita, T; Kuronuma, K; Natsumi, S; Yoshioka, T, 2022) |
| " Since both drugs are extensively metabolized, this study investigated the bioavailability and pharmacokinetics of their co-administration following single-dose administration." | 2.73 | The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. ( Cefali, E; Menon, R; Tolbert, D, 2007) |
| " Adverse events were less frequent in the pravastatin and placebo groups (p < or = 0." | 2.67 | Comparative efficacy and safety of pravastatin, nicotinic acid and the two combined in patients with hypercholesterolemia. ( Connelly, PW; Davignon, J; Gagné, C; Hayden, MR; Hegele, R; Lupien, PJ; McPherson, R; Montigny, M; Roederer, G; Tan, MH, 1994) |
Research
Studies (9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Natsumi, S | 1 |
| Kuroita, T | 1 |
| Ishikawa, T | 1 |
| Kuronuma, K | 1 |
| Yoshioka, T | 1 |
| de Oliveira Alves, A | 1 |
| Bortolato, T | 1 |
| Bernardes Filho, F | 1 |
| AUGER, R | 1 |
| Prousky, J | 1 |
| Seely, D | 1 |
| Cefali, EA | 1 |
| Simmons, PD | 1 |
| Stanek, EJ | 1 |
| Shamp, TR | 1 |
| Menon, R | 1 |
| Tolbert, D | 1 |
| Cefali, E | 1 |
| Davignon, J | 1 |
| Roederer, G | 1 |
| Montigny, M | 1 |
| Hayden, MR | 1 |
| Tan, MH | 1 |
| Connelly, PW | 1 |
| Hegele, R | 1 |
| McPherson, R | 1 |
| Lupien, PJ | 1 |
| Gagné, C | 1 |
| Chojnowska-Jezierska, J | 1 |
| Adamska-Dyniewska, H | 1 |
| Tierson, FD | 1 |
| Olsen, CL | 1 |
| Hook, EB | 1 |
Reviews
1 review available for niacin and Nausea
| Article | Year |
|---|---|
The treatment of migraines and tension-type headaches with intravenous and oral niacin (nicotinic acid): systematic review of the literature.
Topics: Administration, Oral; Analgesia; Clinical Trials as Topic; Energy Metabolism; Female; Flushing; Huma | 2005 |
Trials
4 trials available for niacin and Nausea
| Article | Year |
|---|---|
Improved control of niacin-induced flushing using an optimized once-daily, extended-release niacin formulation.
Topics: Administration, Oral; Adolescent; Adult; Aged; Body Mass Index; Cross-Over Studies; Delayed-Action P | 2006 |
The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Cross-Over Studies; D | 2007 |
Comparative efficacy and safety of pravastatin, nicotinic acid and the two combined in patients with hypercholesterolemia.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Chole | 1994 |
Efficacy and safety of one-year treatment with slow-release nicotinic acid. Monitoring of drug concentration in serum.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Biomarkers; Delayed- | 1998 |
Other Studies
4 other studies available for niacin and Nausea
| Article | Year |
|---|---|
Effect of niacin supplementation on nausea-like behaviour in an isoniazid-induced mouse model of pellagra.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Isoniazid; Mice; Nausea; Niacin; Pellagra; Pic | 2022 |
Pellagra.
Topics: Alcoholism; Diarrhea; Exudates and Transudates; HIV Infections; Humans; Ill-Housed Persons; Male; Mi | 2018 |
[The action of mephecol in digestive intolerance to TH 1314].
Topics: Antitubercular Agents; Humans; Nausea; Niacin; Nicotinic Acids; Tranquilizing Agents; Vomiting | 1959 |
Nausea and vomiting of pregnancy and association with pregnancy outcome.
Topics: Female; Humans; Nausea; Niacin; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Tr | 1986 |