niacin has been researched along with Mitochondrial Diseases in 1 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Equimolar Glu + NA + NAC dosing in a zebrafish vertebrate model of rotenone-based complex I inhibition synergistically rescued larval activity, brain death, lactate, ATP and glutathione levels." | 1.62 | Combinatorial glucose, nicotinic acid and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease. ( Bennett, M; Falk, MJ; Guha, S; Konkwo, C; Kwon, YJ; Mathew, ND; Nakamaru-Ogiso, E; Ostrovsky, J; Polyak, E; Seiler, C; Xiao, R; Zhang, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guha, S | 1 |
| Mathew, ND | 1 |
| Konkwo, C | 1 |
| Ostrovsky, J | 1 |
| Kwon, YJ | 1 |
| Polyak, E | 1 |
| Seiler, C | 1 |
| Bennett, M | 1 |
| Xiao, R | 1 |
| Zhang, Z | 1 |
| Nakamaru-Ogiso, E | 1 |
| Falk, MJ | 1 |
1 other study available for niacin and Mitochondrial Diseases
| Article | Year |
|---|---|
Combinatorial glucose, nicotinic acid and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease.
Topics: Acetylcysteine; Animals; Caenorhabditis elegans; Disease Models, Animal; Drug Synergism; Electron Tr | 2021 |