niacin has been researched along with Malignant Carcinoid Syndrome in 13 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Malignant Carcinoid Syndrome: A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pellagra is a rare clinical syndrome caused by niacin deficiency, and although most commonly nutritional in origin, may be secondary to carcinoid syndrome." | 3.75 | Vulvovaginal pellagra and lichen sclerosus complicating carcinoid syndrome. ( Reichman, O; Sobel, JD, 2009) |
| "Niacin has recently been demonstrated to lower blood pressure in hypertensive patients and to reduce cardiovascular events when combined with a statin." | 2.47 | Pellagra: a review with emphasis on photosensitivity. ( Anstey, A; Moat, S; Wan, P, 2011) |
| "However, diarrhea is also due to factors such as malabsorption." | 2.42 | Complications of midgut carcinoid tumors and carcinoid syndrome. ( de Vries, EG; Kema, IP; Links, TP; van der Horst-Schrivers, AN; Willemse, PH; Wymenga, AN, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reichman, O | 1 |
| Sobel, JD | 1 |
| Wan, P | 1 |
| Moat, S | 1 |
| Anstey, A | 1 |
| Elizalde, I | 1 |
| Borda, F | 1 |
| SPATZ, M | 1 |
| Shah, GM | 1 |
| Shah, RG | 1 |
| Veillette, H | 1 |
| Kirkland, JB | 1 |
| Pasieka, JL | 1 |
| Warner, RR | 1 |
| FLEISCHMAJER, R | 1 |
| HYMAN, AB | 1 |
| EL-MOFTY, AM | 1 |
| van der Horst-Schrivers, AN | 1 |
| Wymenga, AN | 1 |
| Links, TP | 1 |
| Willemse, PH | 1 |
| Kema, IP | 1 |
| de Vries, EG | 1 |
| Bender, DA | 1 |
| Swain, CP | 1 |
| Tavill, AS | 1 |
| Neale, G | 1 |
| Noara, N | 1 |
| Dreizen, S | 1 |
| Castiello, RJ | 1 |
| Lynch, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Tryptophan on Aryl Hydrocarbon Receptor Activation: a Randomized, Double Blind, Placebo-controlled, Crossover Design Pilot Trial[NCT03059862] | 20 participants (Actual) | Interventional | 2017-11-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for niacin and Malignant Carcinoid Syndrome
| Article | Year |
|---|---|
Pellagra: a review with emphasis on photosensitivity.
Topics: Diet; Female; Genital Diseases, Female; Genital Diseases, Male; HIV Infections; Humans; Malabsorptio | 2011 |
[Current treatment of carcinoid tumor].
Topics: Antineoplastic Agents; Carcinoid Heart Disease; Carcinoid Tumor; Combined Modality Therapy; Dietary | 2002 |
Complications of midgut carcinoid tumors and carcinoid syndrome.
Topics: Carcinoid Heart Disease; Carcinoid Tumor; Diarrhea; Flushing; Follow-Up Studies; Humans; Malignant C | 2004 |
Biochemistry of tryptophan in health and disease.
Topics: Animals; Appetite Regulation; Brain Chemistry; Depressive Disorder; Female; Hartnup Disease; Humans; | 1983 |
9 other studies available for niacin and Malignant Carcinoid Syndrome
| Article | Year |
|---|---|
Vulvovaginal pellagra and lichen sclerosus complicating carcinoid syndrome.
Topics: Candidiasis, Vulvovaginal; Diagnostic Errors; Female; Humans; Malignant Carcinoid Syndrome; Niacin; | 2009 |
PATHOGENETIC STUDIES OF EXPERIMENTALLY INDUCED HEART LESIONS AND THEIR RELATION TO THE CARCINOID SYNDROME.
Topics: Chemical and Drug Induced Liver Injury; Deficiency Diseases; Diet; Guinea Pigs; Heart Diseases; Hepa | 1964 |
Biochemical assessment of niacin deficiency among carcinoid cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Carcinoid Tumor; Case-Control Studies; Cohort Studies; Female; Gastr | 2005 |
Clinical significance of derangements of tryptophan metabolism. A review of pellagra, carcinoid and H disease.
Topics: Carcinoid Tumor; Humans; Malignant Carcinoid Syndrome; Pellagra; Tryptophan | 1961 |
DERMATOLOGICAL ASPECT OF ABNORMAL PROTEIN METABOLISM.
Topics: Amyloidosis; Carcinoid Tumor; Carcinoma, Neuroendocrine; Humans; Kwashiorkor; Malignant Carcinoid Sy | 1964 |
Studies of tryptophan and albumin metabolism in a patient with carcinoid syndrome, pellagra, and hypoproteinemia.
Topics: Adult; Body Weight; Female; Humans; Hypoproteinemia; Malignant Carcinoid Syndrome; Niacinamide; Pell | 1976 |
[Erythema (2)].
Topics: Adolescent; Adult; Aged; Child; Dermatomyositis; Diabetic Angiopathies; Erythema; Female; Hartnup Di | 1975 |
The butterfly rash and the malar flush. What diseases do these signs reflect?
Topics: Dermatitis, Seborrheic; Erysipelas; Facial Dermatoses; Flushing; Graft vs Host Disease; Humans; Lupu | 1991 |
Pellagra and the carcinoid syndrome.
Topics: Digitalis Glycosides; Diuretics; Female; Fluorouracil; Humans; Malignant Carcinoid Syndrome; Middle | 1972 |