Page last updated: 2024-10-19

niacin and MS (Multiple Sclerosis)

niacin has been researched along with MS (Multiple Sclerosis) in 13 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Research Excerpts

ExcerptRelevanceReference
"Remyelination following CNS demyelination restores rapid signal propagation and protects axons; however, its efficiency declines with increasing age."5.56Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. ( Alaeiilkhchi, N; Calvert, F; Franklin, RJM; Gaffney, DJ; Ghosh, T; Kappen, J; Kaushik, DK; Keough, MB; Knights, AJ; Kolehmainen, KL; Lozinski, B; Michaels, NJ; Mirzaei, R; Mishra, MK; Plemel, JR; Pu, A; Rawji, KS; Tang, W; Tetzlaff, W; Yong, VW; Young, AMH; Zein, S, 2020)
"Remyelination following CNS demyelination restores rapid signal propagation and protects axons; however, its efficiency declines with increasing age."1.56Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. ( Alaeiilkhchi, N; Calvert, F; Franklin, RJM; Gaffney, DJ; Ghosh, T; Kappen, J; Kaushik, DK; Keough, MB; Knights, AJ; Kolehmainen, KL; Lozinski, B; Michaels, NJ; Mirzaei, R; Mishra, MK; Plemel, JR; Pu, A; Rawji, KS; Tang, W; Tetzlaff, W; Yong, VW; Young, AMH; Zein, S, 2020)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Rawji, KS1
Young, AMH1
Ghosh, T1
Michaels, NJ1
Mirzaei, R1
Kappen, J1
Kolehmainen, KL1
Alaeiilkhchi, N1
Lozinski, B1
Mishra, MK1
Pu, A1
Tang, W1
Zein, S1
Kaushik, DK1
Keough, MB1
Plemel, JR1
Calvert, F1
Knights, AJ1
Gaffney, DJ1
Tetzlaff, W1
Franklin, RJM1
Yong, VW1
Evans, E1
Piccio, L1
Cross, AH1
Offermanns, S1
Schwaninger, M1
KURTZKE, JF1
BERLIN, L1
DEKABAN, A1
KORENGOLD, MC1
HAASE, GR1
BERG, LR1
MAGEE, KR1
LONNUM, A1
HINTERBUCHNER, LP1
GOLDNER, MG1
ROGOFF, JB1
RABINER, AM1
AHRINGSMANN, H1
ANGST, J1
STERN, FH1
TSCHABITSCHER, H1
WANKO, T1
SCHINKO, H1
FUST, B1
MONTGOMERY, RD1
CRUICKSHANK, EK1
ROBERTSON, WB1
MCMENEMEY, WH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Adjuvant Effects of Vitamin A and Vitamin D Supplementation on Treatment of Children With ADHD:A Randomized, Double Blind, Placebo-controlled, Multicentric Trial.[NCT04284059]Phase 4504 participants (Anticipated)Interventional2021-02-25Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for niacin and MS (Multiple Sclerosis)

ArticleYear
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
    JAMA neurology, 2018, 08-01, Volume: 75, Issue:8

    Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements;

2018
Nutritional or pharmacological activation of HCA(2) ameliorates neuroinflammation.
    Trends in molecular medicine, 2015, Volume: 21, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adenylyl Cyclases; Animals; Brain; Brain Ischemia; Diet, Ketogenic; Dimethyl

2015

Other Studies

11 other studies available for niacin and MS (Multiple Sclerosis)

ArticleYear
Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system.
    Acta neuropathologica, 2020, Volume: 139, Issue:5

    Topics: Aging; Animals; Axons; Demyelinating Diseases; Humans; Macrophages; Mice, Transgenic; Microglia; Mul

2020
The effects of isoniazid on patients with multiple sclerosis; preliminary report.
    American review of tuberculosis, 1954, Volume: 70, Issue:4

    Topics: Isomerism; Isoniazid; Multiple Sclerosis; Niacin; Nicotinic Acids; Psychotherapy, Multiple

1954
Failure in treatment of multiple sclerosis patients with isoniazid.
    Canadian Medical Association journal, 1955, Sep-15, Volume: 73, Issue:6

    Topics: Isomerism; Isoniazid; Multiple Sclerosis; Niacin; Nicotinic Acids; Psychotherapy, Multiple

1955
Isonicotinic acid hydrazide in multiple sclerosis.
    Neurology, 1955, Volume: 5, Issue:11

    Topics: Isoniazid; Multiple Sclerosis; Niacin; Nicotinic Acids

1955
[Isoniazid in the treatment of multiple sclerosis].
    Nordisk medicin, 1955, Aug-25, Volume: 54, Issue:34

    Topics: Isomerism; Isoniazid; Multiple Sclerosis; Niacin; Nicotinic Acids; Psychotherapy, Multiple

1955
Effect of isoniazid in multiple sclerosis with chronic symptomatology.
    A.M.A. archives of neurology and psychiatry, 1956, Volume: 75, Issue:2

    Topics: Isomerism; Isoniazid; Multiple Sclerosis; Niacin; Nicotinic Acids; Psychotherapy, Multiple

1956
[The presently possible therapy of multiple sclerosis and its significance for the etiology of the disease].
    Hippokrates, 1955, Oct-15, Volume: 26, Issue:19

    Topics: Diet; Isomerism; Multiple Sclerosis; Niacin; Nicotinic Acids; Psychotherapy, Multiple; Rest

1955
[Treatment of multiple sclerosis with rimifon and marsilid].
    Schweizerische medizinische Wochenschrift, 1956, May-19, Volume: 86, Issue:20

    Topics: Isomerism; Isoniazid; Multiple Sclerosis; Niacin; Nicotinic Acids; Psychotherapy, Multiple

1956
COMPARISON OF THREE AGENTS (TIGACOL, DRAMAMINE AND ANTIVERT) FOR THE CONTROL OF DIZZINESS IN GERIATRIC PATIENTS.
    Journal of the American Geriatrics Society, 1963, Volume: 11

    Topics: Alcohols; Benzamides; Cochlear Nerve; Dimenhydrinate; Dizziness; Geriatrics; Humans; Intracranial Ar

1963
[Therapy and etiology of multiple sclerosis; preliminary report].
    Schweizerische medizinische Wochenschrift, 1955, Jun-04, Volume: 85, Issue:23

    Topics: Isomerism; Multiple Sclerosis; Niacin; Nicotinic Acids; Psychotherapy, Multiple

1955
CLINICAL AND PATHOLOGICAL OBSERVATIONS ON JAMAICAN NEUROPATHY; A REPORT ON 206 CASES.
    Brain : a journal of neurology, 1964, Volume: 87

    Topics: Amblyopia; Arachnoid; Ataxia; Central Nervous System Diseases; Humans; Lathyrism; Meningitis; Multip

1964