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niacin and Liver Steatosis

niacin has been researched along with Liver Steatosis in 21 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Research Excerpts

ExcerptRelevanceReference
"Fatty liver is caused when rats are given orotic acid of the pyrimidine base in large quantities."7.81Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats. ( Fukuwatari, T; Kawamura, T; Morita, N; Shibata, K; Tsuji, A, 2015)
"Niacin treatment to rats with preexisting hepatic steatosis induced by the HF diet significantly regressed steatosis."5.40Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. ( Ganji, SH; Kamanna, VS; Kashyap, ML; Kukes, GD; Lambrecht, N, 2014)
" Dyslipidemia in patients with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis may improve with use of statins, fibrates, niacin, and thiazolidinediones, but the data are presently very limited."4.82Management of dyslipidemia in patients with complicated metabolic syndrome. ( Davidson, MH, 2005)
"Fatty liver is caused when rats are given orotic acid of the pyrimidine base in large quantities."3.81Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats. ( Fukuwatari, T; Kawamura, T; Morita, N; Shibata, K; Tsuji, A, 2015)
"Hepatotoxicity is a potential side effect of niacin therapy for hypercholesterolemia, ranging from mild aminotransferase elevation to fulminant hepatic failure."3.68Transient focal hepatic defects related to sustained-release niacin. ( Lawrence, SP, 1993)
"Niacin treatment to rats with preexisting hepatic steatosis induced by the HF diet significantly regressed steatosis."1.40Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. ( Ganji, SH; Kamanna, VS; Kashyap, ML; Kukes, GD; Lambrecht, N, 2014)
"Fatty liver is the accumulation of fat in liver cells, which leads to disruption of the normal liver structure and function."1.34A novel therapeutic drug (copper nicotinic acid complex) for non-alcoholic fatty liver. ( Mohamed, HH; Nafady, AA; Nassar, AY; Salama, RH, 2007)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199011 (52.38)18.7374
1990's2 (9.52)18.2507
2000's3 (14.29)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdalla, H1
Bernardo, JF1
Ganji, SH1
Kukes, GD1
Lambrecht, N1
Kashyap, ML1
Kamanna, VS1
Misra, A1
Bhardwaj, S1
Shibata, K2
Morita, N1
Kawamura, T1
Tsuji, A1
Fukuwatari, T2
Fabbrini, E1
Mohammed, BS1
Korenblat, KM1
Magkos, F1
McCrea, J1
Patterson, BW1
Klein, S1
Morikawa, Y1
Sugimoto, E1
MCKENNIS, H1
YARD, AS1
PAHNELAS, EV1
CHIZZOLINI, M1
ESPOSITO, S1
NICROSINI, F1
PETRONIO, L1
CARLSON, LA1
LILJEDAHL, SO1
Baker, H2
Frank, O2
Ziffer, H1
Goldfarb, S1
Leevy, CM2
Sobotka, H1
Rikans, LL2
Arata, D2
Cederquist, DC2
Tenhove, W1
Cherrick, GR1
TYNER, EP1
LEWIS, HB1
ECKSTEIN, HC1
Davidson, MH1
Salama, RH1
Nassar, AY1
Nafady, AA1
Mohamed, HH1
Lawrence, SP1
Herdt, TH1
Emery, RS1

Reviews

2 reviews available for niacin and Liver Steatosis

ArticleYear
Management of dyslipidemia in patients with complicated metabolic syndrome.
    The American journal of cardiology, 2005, Aug-22, Volume: 96, Issue:4A

    Topics: Clofibric Acid; Fatty Liver; HIV-Associated Lipodystrophy Syndrome; Humans; Hydroxymethylglutaryl-Co

2005
Therapy of diseases of ruminant intermediary metabolism.
    The Veterinary clinics of North America. Food animal practice, 1992, Volume: 8, Issue:1

    Topics: Animals; Cattle; Cattle Diseases; Fatty Liver; Female; Glucocorticoids; Glucose; Insulin; Ketosis; N

1992

Trials

1 trial available for niacin and Liver Steatosis

ArticleYear
Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:6

    Topics: Adult; Apolipoproteins B; Blood Glucose; Body Composition; Double-Blind Method; Fatty Acids, Noneste

2010

Other Studies

18 other studies available for niacin and Liver Steatosis

ArticleYear
The Case | Life-threatening lactic acidosis in a patient with jaundice and liver masses.
    Kidney international, 2018, Volume: 93, Issue:3

    Topics: Acidosis, Lactic; Adult; Antidotes; Dietary Supplements; Fatty Liver; Fomepizole; Humans; Jaundice;

2018
Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Feb-15, Volume: 306, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Disease Progression; Fatty

2014
Management of the Metabolic Syndrome and the Obese Patient with Metabolic Disturbances: South Asian Perspective.
    Nestle Nutrition Institute workshop series, 2015, Volume: 82

    Topics: Adipose Tissue; Asia; Asian People; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet; Dietar

2015
Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats.
    Journal of nutritional science and vitaminology, 2015, Volume: 61, Issue:5

    Topics: Animals; Biotin; Fatty Liver; Folic Acid; Liver; Male; Niacin; Orotic Acid; Pantothenic Acid; Rats;

2015
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:6

    Topics: Animals; Diet; Fats; Fatty Liver; Feeding Behavior; Liver; Male; NAD; NADP; Niacin; Organ Size; Orot

2002
The production of fatty livers in rabbits by isoniazid and other hydrazine derivatives.
    American review of tuberculosis, 1956, Volume: 73, Issue:6

    Topics: Animals; Fatty Liver; Hydrazines; Isoniazid; Liver Diseases; Niacin; Nicotinic Acids; Rabbits

1956
[Liver protective effect of trigonelline on fatty liver from carbon tetrachloride; experimental research].
    Rivista d'ostetricia e ginecologia pratica, 1957, Volume: 39, Issue:5

    Topics: Alkaloids; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Fatty Liver; Niacin

1957
[The nature and prevention of hepatic steatosis caused by massive doses of nicotinamide and 6-aminonicotinamide].
    Archivio per le scienze mediche, 1959, Volume: 108

    Topics: 6-Aminonicotinamide; Fatty Liver; Liver Diseases; Niacin; Niacinamide; Nicotinic Acids

1959
Lipid metabolism and trauma. II. Studies on the effect of nicotinic acid on norepinephrine induced fatty liver.
    Acta medica Scandinavica, 1963, Volume: 173

    Topics: Blood Pressure Determination; Fatty Acids; Fatty Liver; Glycerides; Lipid Metabolism; Lipids; Niacin

1963
EFFECT OF HEPATIC DISEASE ON LIVER B-COMPLEX VITAMIN TITERS.
    The American journal of clinical nutrition, 1964, Volume: 14

    Topics: Alcoholism; Biological Assay; Biopsy; Biotin; Fatty Liver; Folic Acid; Humans; Liver; Liver Cirrhosi

1964
FATTY LIVERS PRODUCED IN ALBINO RATS BY EXCESS NIACIN IN HIGH FAT DIETS. I. ALTERATIONS IN ENZYME AND COENZYME SYSTEMS INDUCED BY SUPPLEMENTING 40 PERCENT FAT DIETS WITH O.1 PERCENT OF NIACIN.
    The Journal of nutrition, 1964, Volume: 82

    Topics: Blood Chemical Analysis; Caseins; Coenzymes; Diet, High-Fat; Dietary Fats; Dietary Supplements; Fatt

1964
FATTY LIVERS PRODUCED IN ALBINO RATS BY EXCESS NIACIN IN HIGH FAT DIETS. II. EFFECT OF CHOLINE SUPPLEMENTS.
    The Journal of nutrition, 1965, Volume: 85

    Topics: Alkaline Phosphatase; Blood Chemical Analysis; Body Weight; Choline; Choline Deficiency; Diet Therap

1965
B-COMPLEX VITAMINS IN LIVER DISEASE OF THE ALCOHOLIC.
    The American journal of clinical nutrition, 1965, Volume: 16

    Topics: Alcoholism; Autoradiography; Biopsy; Biotin; Blood Chemical Analysis; DNA; Drug Therapy; Fatty Liver

1965
Niacin and the ability of cystine to augment deposition of liver fat.
    The Journal of biological chemistry, 1950, Volume: 187, Issue:2

    Topics: Cystine; Fatty Liver; Liver; Niacin; Nicotinic Acids

1950
A novel therapeutic drug (copper nicotinic acid complex) for non-alcoholic fatty liver.
    Liver international : official journal of the International Association for the Study of the Liver, 2007, Volume: 27, Issue:4

    Topics: Animals; Body Weight; Clinical Enzyme Tests; Copper; Drug Evaluation, Preclinical; Fatty Liver; Lipi

2007
Nutrition classics. Proceedings of the Society for Experimental Biology and Medicine, volume 38, 1938: Toxicity of nicotinic acid. K. K. Chen, Charles L. Rose and E. Brown Robbins.
    Nutrition reviews, 1984, Volume: 42, Issue:2

    Topics: Animals; Dogs; Fatty Liver; History, 20th Century; Indiana; Niacin; Vitamin B Complex

1984
Transient focal hepatic defects related to sustained-release niacin.
    Journal of clinical gastroenterology, 1993, Volume: 16, Issue:3

    Topics: Adult; Chemical and Drug Induced Liver Injury; Delayed-Action Preparations; Fatty Liver; Female; Hum

1993
Kwashiorkor. A nutritional disease of children associated with a maize diet by Cicely D. Williams from the Lancet, Nov. 16, 1935, p. 1151.
    Nutrition reviews, 1973, Volume: 31

    Topics: Acrodynia; Avitaminosis; Child, Preschool; Diagnosis, Differential; Diet; Fatty Liver; Ghana; Histor

1973