niacin has been researched along with Liver Steatosis in 21 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Excerpt | Relevance | Reference |
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"Fatty liver is caused when rats are given orotic acid of the pyrimidine base in large quantities." | 7.81 | Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats. ( Fukuwatari, T; Kawamura, T; Morita, N; Shibata, K; Tsuji, A, 2015) |
"Niacin treatment to rats with preexisting hepatic steatosis induced by the HF diet significantly regressed steatosis." | 5.40 | Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. ( Ganji, SH; Kamanna, VS; Kashyap, ML; Kukes, GD; Lambrecht, N, 2014) |
" Dyslipidemia in patients with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis may improve with use of statins, fibrates, niacin, and thiazolidinediones, but the data are presently very limited." | 4.82 | Management of dyslipidemia in patients with complicated metabolic syndrome. ( Davidson, MH, 2005) |
"Fatty liver is caused when rats are given orotic acid of the pyrimidine base in large quantities." | 3.81 | Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats. ( Fukuwatari, T; Kawamura, T; Morita, N; Shibata, K; Tsuji, A, 2015) |
"Hepatotoxicity is a potential side effect of niacin therapy for hypercholesterolemia, ranging from mild aminotransferase elevation to fulminant hepatic failure." | 3.68 | Transient focal hepatic defects related to sustained-release niacin. ( Lawrence, SP, 1993) |
"Niacin treatment to rats with preexisting hepatic steatosis induced by the HF diet significantly regressed steatosis." | 1.40 | Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. ( Ganji, SH; Kamanna, VS; Kashyap, ML; Kukes, GD; Lambrecht, N, 2014) |
"Fatty liver is the accumulation of fat in liver cells, which leads to disruption of the normal liver structure and function." | 1.34 | A novel therapeutic drug (copper nicotinic acid complex) for non-alcoholic fatty liver. ( Mohamed, HH; Nafady, AA; Nassar, AY; Salama, RH, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (52.38) | 18.7374 |
1990's | 2 (9.52) | 18.2507 |
2000's | 3 (14.29) | 29.6817 |
2010's | 5 (23.81) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Abdalla, H | 1 |
Bernardo, JF | 1 |
Ganji, SH | 1 |
Kukes, GD | 1 |
Lambrecht, N | 1 |
Kashyap, ML | 1 |
Kamanna, VS | 1 |
Misra, A | 1 |
Bhardwaj, S | 1 |
Shibata, K | 2 |
Morita, N | 1 |
Kawamura, T | 1 |
Tsuji, A | 1 |
Fukuwatari, T | 2 |
Fabbrini, E | 1 |
Mohammed, BS | 1 |
Korenblat, KM | 1 |
Magkos, F | 1 |
McCrea, J | 1 |
Patterson, BW | 1 |
Klein, S | 1 |
Morikawa, Y | 1 |
Sugimoto, E | 1 |
MCKENNIS, H | 1 |
YARD, AS | 1 |
PAHNELAS, EV | 1 |
CHIZZOLINI, M | 1 |
ESPOSITO, S | 1 |
NICROSINI, F | 1 |
PETRONIO, L | 1 |
CARLSON, LA | 1 |
LILJEDAHL, SO | 1 |
Baker, H | 2 |
Frank, O | 2 |
Ziffer, H | 1 |
Goldfarb, S | 1 |
Leevy, CM | 2 |
Sobotka, H | 1 |
Rikans, LL | 2 |
Arata, D | 2 |
Cederquist, DC | 2 |
Tenhove, W | 1 |
Cherrick, GR | 1 |
TYNER, EP | 1 |
LEWIS, HB | 1 |
ECKSTEIN, HC | 1 |
Davidson, MH | 1 |
Salama, RH | 1 |
Nassar, AY | 1 |
Nafady, AA | 1 |
Mohamed, HH | 1 |
Lawrence, SP | 1 |
Herdt, TH | 1 |
Emery, RS | 1 |
2 reviews available for niacin and Liver Steatosis
Article | Year |
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Management of dyslipidemia in patients with complicated metabolic syndrome.
Topics: Clofibric Acid; Fatty Liver; HIV-Associated Lipodystrophy Syndrome; Humans; Hydroxymethylglutaryl-Co | 2005 |
Therapy of diseases of ruminant intermediary metabolism.
Topics: Animals; Cattle; Cattle Diseases; Fatty Liver; Female; Glucocorticoids; Glucose; Insulin; Ketosis; N | 1992 |
1 trial available for niacin and Liver Steatosis
Article | Year |
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Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease.
Topics: Adult; Apolipoproteins B; Blood Glucose; Body Composition; Double-Blind Method; Fatty Acids, Noneste | 2010 |
18 other studies available for niacin and Liver Steatosis
Article | Year |
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The Case | Life-threatening lactic acidosis in a patient with jaundice and liver masses.
Topics: Acidosis, Lactic; Adult; Antidotes; Dietary Supplements; Fatty Liver; Fomepizole; Humans; Jaundice; | 2018 |
Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Disease Progression; Fatty | 2014 |
Management of the Metabolic Syndrome and the Obese Patient with Metabolic Disturbances: South Asian Perspective.
Topics: Adipose Tissue; Asia; Asian People; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet; Dietar | 2015 |
Effects of Fatty Liver Induced by Excess Orotic Acid on B-Group Vitamin Concentrations of Liver, Blood, and Urine in Rats.
Topics: Animals; Biotin; Fatty Liver; Folic Acid; Liver; Male; Niacin; Orotic Acid; Pantothenic Acid; Rats; | 2015 |
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
Topics: Animals; Diet; Fats; Fatty Liver; Feeding Behavior; Liver; Male; NAD; NADP; Niacin; Organ Size; Orot | 2002 |
The production of fatty livers in rabbits by isoniazid and other hydrazine derivatives.
Topics: Animals; Fatty Liver; Hydrazines; Isoniazid; Liver Diseases; Niacin; Nicotinic Acids; Rabbits | 1956 |
[Liver protective effect of trigonelline on fatty liver from carbon tetrachloride; experimental research].
Topics: Alkaloids; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Fatty Liver; Niacin | 1957 |
[The nature and prevention of hepatic steatosis caused by massive doses of nicotinamide and 6-aminonicotinamide].
Topics: 6-Aminonicotinamide; Fatty Liver; Liver Diseases; Niacin; Niacinamide; Nicotinic Acids | 1959 |
Lipid metabolism and trauma. II. Studies on the effect of nicotinic acid on norepinephrine induced fatty liver.
Topics: Blood Pressure Determination; Fatty Acids; Fatty Liver; Glycerides; Lipid Metabolism; Lipids; Niacin | 1963 |
EFFECT OF HEPATIC DISEASE ON LIVER B-COMPLEX VITAMIN TITERS.
Topics: Alcoholism; Biological Assay; Biopsy; Biotin; Fatty Liver; Folic Acid; Humans; Liver; Liver Cirrhosi | 1964 |
FATTY LIVERS PRODUCED IN ALBINO RATS BY EXCESS NIACIN IN HIGH FAT DIETS. I. ALTERATIONS IN ENZYME AND COENZYME SYSTEMS INDUCED BY SUPPLEMENTING 40 PERCENT FAT DIETS WITH O.1 PERCENT OF NIACIN.
Topics: Blood Chemical Analysis; Caseins; Coenzymes; Diet, High-Fat; Dietary Fats; Dietary Supplements; Fatt | 1964 |
FATTY LIVERS PRODUCED IN ALBINO RATS BY EXCESS NIACIN IN HIGH FAT DIETS. II. EFFECT OF CHOLINE SUPPLEMENTS.
Topics: Alkaline Phosphatase; Blood Chemical Analysis; Body Weight; Choline; Choline Deficiency; Diet Therap | 1965 |
B-COMPLEX VITAMINS IN LIVER DISEASE OF THE ALCOHOLIC.
Topics: Alcoholism; Autoradiography; Biopsy; Biotin; Blood Chemical Analysis; DNA; Drug Therapy; Fatty Liver | 1965 |
Niacin and the ability of cystine to augment deposition of liver fat.
Topics: Cystine; Fatty Liver; Liver; Niacin; Nicotinic Acids | 1950 |
A novel therapeutic drug (copper nicotinic acid complex) for non-alcoholic fatty liver.
Topics: Animals; Body Weight; Clinical Enzyme Tests; Copper; Drug Evaluation, Preclinical; Fatty Liver; Lipi | 2007 |
Nutrition classics. Proceedings of the Society for Experimental Biology and Medicine, volume 38, 1938: Toxicity of nicotinic acid. K. K. Chen, Charles L. Rose and E. Brown Robbins.
Topics: Animals; Dogs; Fatty Liver; History, 20th Century; Indiana; Niacin; Vitamin B Complex | 1984 |
Transient focal hepatic defects related to sustained-release niacin.
Topics: Adult; Chemical and Drug Induced Liver Injury; Delayed-Action Preparations; Fatty Liver; Female; Hum | 1993 |
Kwashiorkor. A nutritional disease of children associated with a maize diet by Cicely D. Williams from the Lancet, Nov. 16, 1935, p. 1151.
Topics: Acrodynia; Avitaminosis; Child, Preschool; Diagnosis, Differential; Diet; Fatty Liver; Ghana; Histor | 1973 |