Page last updated: 2024-10-19

niacin and Leukemia

niacin has been researched along with Leukemia in 7 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"Vegetables intake was associated with decreased risk of adult leukemia, with a significant dose-response relationship and adjusted OR of 0."1.42Diet and risk of adult leukemia: a multicenter case-control study in China. ( Holman, CD; Jin, J; Liu, P; Zhang, M, 2015)
"Niacin deficiency causes dramatic genomic instability in bone marrow cells in an in vivo rat model."1.38Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis. ( Kirkland, JB, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cagnetta, A1
Caffa, I1
Acharya, C1
Soncini, D1
Acharya, P1
Adamia, S1
Pierri, I1
Bergamaschi, M1
Garuti, A1
Fraternali, G1
Mastracci, L1
Provenzani, A1
Zucal, C1
Damonte, G1
Salis, A1
Montecucco, F1
Patrone, F1
Ballestrero, A1
Bruzzone, S1
Gobbi, M1
Nencioni, A1
Cea, M1
Liu, P1
Holman, CD1
Jin, J1
Zhang, M1
Kirkland, JB2
BUDILLON, G1
ALIFANO, A1
GADALETA, MN1
COLTORTI, M1
IVANOVA, VD1
RAUSHENBAKH, MO1
BOEHNEL, J1
STACHER, A1

Reviews

1 review available for niacin and Leukemia

ArticleYear
Niacin status and treatment-related leukemogenesis.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Humans; Leukemia; Niacin; Nutritional

2009

Other Studies

6 other studies available for niacin and Leukemia

ArticleYear
APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Sep-01, Volume: 21, Issue:17

    Topics: Acrylamides; Adenosine Triphosphate; Aged; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Tr

2015
Diet and risk of adult leukemia: a multicenter case-control study in China.
    Cancer causes & control : CCC, 2015, Volume: 26, Issue:8

    Topics: Adult; Aged; Animals; Ascorbic Acid; Carotenoids; Case-Control Studies; China; Diet; Dietary Fiber;

2015
Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis.
    Sub-cellular biochemistry, 2012, Volume: 56

    Topics: Animals; Avitaminosis; Bone Marrow Cells; Cell Transformation, Neoplastic; Disease Models, Animal; D

2012
[Tryptophan conversion to nicotinic acid in mice with Friend's leukemia. I. 3-Hydroxyanthranilic acid oxidase activity].
    Bollettino della Societa italiana di biologia sperimentale, 1962, Dec-31, Volume: 38

    Topics: Animals; Friends; Leukemia; Leukemia, Experimental; Mice; Niacin; Nicotinic Acids; ortho-Aminobenzoa

1962
[TRYPTOPHAN METABOLISM IN LEUKEMIA].
    Problemy gematologii i perelivaniia krovi, 1964, Volume: 9

    Topics: Anemia; Anemia, Aplastic; Chromatography; Drug Therapy; Hodgkin Disease; Humans; Indoles; Leukemia;

1964
[EXPERIENCES WITH A PREDNISOLONE NICOTINIC ACID ESTER IN HEMATOLOGIC DISEASES].
    Therapeutische Umschau. Revue therapeutique, 1964, Volume: 21

    Topics: Drug Therapy; Hematologic Diseases; Hodgkin Disease; Leukemia; Niacin; Nicotinic Acids; Prednisolone

1964