niacin has been researched along with Itching in 10 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To increase the probability of flushing, subjects were administered niacin ER at the upper limit of the approved dosage range (2,000 mg), and were precluded from using aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) during the study." | 9.12 | Improved control of niacin-induced flushing using an optimized once-daily, extended-release niacin formulation. ( Cefali, EA; Shamp, TR; Simmons, PD; Stanek, EJ, 2006) |
| "We conducted a double-blind, randomized, parallel group study to examine and compare the antipruritic effects of promethazine, niacin, prednisolone and their combination on pruritus induced by chloroquine, in 28 historical itching patients with parasitologically proven malaria fever." | 9.08 | Chloroquine-induced pruritus in malaria fever: contribution of malaria parasitaemia and the effects of prednisolone, niacin, and their combination, compared with antihistamine. ( Adebayo, RA; Ajayi, AA; Onayemi, O; Sofowora, GG; Udoh, SJ, 1997) |
| "Chloroquine chemotherapy of malaria fever induces severe generalised pruritus in a large proportion of black Africans." | 9.07 | The effects of prednisolone and niacin on chloroquine-induced pruritus in malaria. ( Ajayi, AA; Ajayi, OO; Akinleye, AO; Ijaware, CO; Oyelese, O; Udoh, SJ, 1991) |
| "The relationship of the exanthematous eruption with lower body weight and the increase in dosage suggests a pharmacokinetic effect that may be related to increased exposure to niacin or its metabolites and provoked by inhibition of the DP1 receptor with laropiprant, as we have not seen this rash with niacin used alone." | 7.79 | A high incidence of exanthematous eruption associated with niacin/laropiprant combination in Hong Kong Chinese patients. ( Chang, M; Hu, M; Tomlinson, B; Yang, YL, 2013) |
| " To increase the probability of flushing, subjects were administered niacin ER at the upper limit of the approved dosage range (2,000 mg), and were precluded from using aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) during the study." | 5.12 | Improved control of niacin-induced flushing using an optimized once-daily, extended-release niacin formulation. ( Cefali, EA; Shamp, TR; Simmons, PD; Stanek, EJ, 2006) |
| "We conducted a double-blind, randomized, parallel group study to examine and compare the antipruritic effects of promethazine, niacin, prednisolone and their combination on pruritus induced by chloroquine, in 28 historical itching patients with parasitologically proven malaria fever." | 5.08 | Chloroquine-induced pruritus in malaria fever: contribution of malaria parasitaemia and the effects of prednisolone, niacin, and their combination, compared with antihistamine. ( Adebayo, RA; Ajayi, AA; Onayemi, O; Sofowora, GG; Udoh, SJ, 1997) |
| "The symptom scores for flushing, itching, tingling, and warmth were all significantly reduced by both aspirin regimens (p < ." | 5.08 | Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions. ( Campbell, JR; Jungnickel, PW; Maloley, PA; Peddicord, TE; Vander Tuin, EL, 1997) |
| "It appears from this pilot study that preceding niacin with 325 mg of aspirin will decrease the warmth and flushing associated with niacin." | 5.07 | The effect of aspirin on niacin-induced cutaneous reactions. ( Fowler, SF; Hainer, BL; Price, SO; Whelan, AM, 1992) |
| "Chloroquine chemotherapy of malaria fever induces severe generalised pruritus in a large proportion of black Africans." | 5.07 | The effects of prednisolone and niacin on chloroquine-induced pruritus in malaria. ( Ajayi, AA; Ajayi, OO; Akinleye, AO; Ijaware, CO; Oyelese, O; Udoh, SJ, 1991) |
| "The relationship of the exanthematous eruption with lower body weight and the increase in dosage suggests a pharmacokinetic effect that may be related to increased exposure to niacin or its metabolites and provoked by inhibition of the DP1 receptor with laropiprant, as we have not seen this rash with niacin used alone." | 3.79 | A high incidence of exanthematous eruption associated with niacin/laropiprant combination in Hong Kong Chinese patients. ( Chang, M; Hu, M; Tomlinson, B; Yang, YL, 2013) |
| " There is a need for further research in order to come to a clear conclusion regarding combined therapies of aspirin and laropiprant pretreatment, as well as exact dosage requirements." | 2.45 | Mechanisms of flushing due to niacin and abolition of these effects. ( Arora, R; Sood, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yano, H | 1 |
| Kinjo, M | 1 |
| Hagiwara, A | 1 |
| Fujimura, T | 1 |
| Furudate, S | 1 |
| Kambayashi, Y | 1 |
| Numata, Y | 1 |
| Haga, T | 1 |
| Aiba, S | 1 |
| Yang, YL | 1 |
| Hu, M | 1 |
| Chang, M | 1 |
| Tomlinson, B | 1 |
| Sood, A | 1 |
| Arora, R | 1 |
| Cefali, EA | 1 |
| Simmons, PD | 1 |
| Stanek, EJ | 1 |
| Shamp, TR | 1 |
| Adebayo, RA | 1 |
| Sofowora, GG | 1 |
| Onayemi, O | 1 |
| Udoh, SJ | 2 |
| Ajayi, AA | 2 |
| Jungnickel, PW | 1 |
| Maloley, PA | 1 |
| Vander Tuin, EL | 1 |
| Peddicord, TE | 1 |
| Campbell, JR | 1 |
| Long, CC | 1 |
| Marks, R | 1 |
| Whelan, AM | 1 |
| Price, SO | 1 |
| Fowler, SF | 1 |
| Hainer, BL | 1 |
| Akinleye, AO | 1 |
| Ajayi, OO | 1 |
| Oyelese, O | 1 |
| Ijaware, CO | 1 |
1 review available for niacin and Itching
| Article | Year |
|---|---|
Mechanisms of flushing due to niacin and abolition of these effects.
Topics: Aspirin; Dose-Response Relationship, Drug; Dyslipidemias; Humans; Hypolipidemic Agents; Indoles; Nia | 2009 |
5 trials available for niacin and Itching
| Article | Year |
|---|---|
Improved control of niacin-induced flushing using an optimized once-daily, extended-release niacin formulation.
Topics: Administration, Oral; Adolescent; Adult; Aged; Body Mass Index; Cross-Over Studies; Delayed-Action P | 2006 |
Chloroquine-induced pruritus in malaria fever: contribution of malaria parasitaemia and the effects of prednisolone, niacin, and their combination, compared with antihistamine.
Topics: Adult; Animals; Antimalarials; Area Under Curve; Chloroquine; Double-Blind Method; Drug Therapy, Com | 1997 |
Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions.
Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Stud | 1997 |
The effect of aspirin on niacin-induced cutaneous reactions.
Topics: Adult; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Flushing; Humans; Hyperlipid | 1992 |
The effects of prednisolone and niacin on chloroquine-induced pruritus in malaria.
Topics: Adult; Chloroquine; Double-Blind Method; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Mal | 1991 |
4 other studies available for niacin and Itching
| Article | Year |
|---|---|
Pruritic Rash and Diarrhea.
Topics: Aged, 80 and over; Diarrhea; Exanthema; Fatal Outcome; Female; Humans; Niacin; Pellagra; Pruritus; S | 2021 |
Generalized granulomatous dermatitis accompanied by myelodysplastic syndrome.
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Anti-Bacterial Agents; Dermatitis; Doxycycline; For | 2014 |
A high incidence of exanthematous eruption associated with niacin/laropiprant combination in Hong Kong Chinese patients.
Topics: Adult; Aged; Anti-Inflammatory Agents; Biopsy; Body Weight; Drug Combinations; Drug Eruptions; Exant | 2013 |
Stratum corneum changes in patients with senile pruritus.
Topics: Aged; Aged, 80 and over; Baths; Benzocaine; Circadian Rhythm; Cornea; Drug Combinations; Electric Co | 1992 |