niacin and Ischemia
niacin has been researched along with Ischemia in 22 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niacin was shown to inhibit acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids." | 5.38 | Niacin improves ischemia-induced neovascularization in diabetic mice by enhancement of endothelial progenitor cell functions independent of changes in plasma lipids. ( Chen, JS; Chen, JW; Chiang, CH; Huang, PH; Leu, HB; Lin, CP; Lin, FY; Lin, SJ; Tsai, HY; Wang, CH; Wu, TC, 2012) |
| " The effects of vitamin D, alone or in combination with niacin, on endothelial cell (EC) angiogenic function and on revascularization in obese animals with peripheral ischemia are unknown." | 3.91 | Vitamin D intervention does not improve vascular regeneration in diet-induced obese male mice with peripheral ischemia. ( Borradaile, NM; Nong, Z; Park, C; Peters, KM; Pickering, JG; Sawyez, CG; Sutherland, BG; Wilson, RB; Yin, H; Zhang, R, 2019) |
| "Early-stage detection of chronic kidney diseases (CKD) is important to treatment that may slow and occasionally halt CKD progression." | 3.01 | The complexity of nicotinamide adenine dinucleotide (NAD), hypoxic, and aryl hydrocarbon receptor cell signaling in chronic kidney disease. ( Curran, CS; Kopp, JB, 2023) |
| "Niacin was shown to inhibit acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids." | 1.38 | Niacin improves ischemia-induced neovascularization in diabetic mice by enhancement of endothelial progenitor cell functions independent of changes in plasma lipids. ( Chen, JS; Chen, JW; Chiang, CH; Huang, PH; Leu, HB; Lin, CP; Lin, FY; Lin, SJ; Tsai, HY; Wang, CH; Wu, TC, 2012) |
| "Isoniazid was capable of stimulating wound-healing in ischemic tissue to the level of nonischemic wounds and might offer a novel treatment option for wounds associated with arterial insufficiency." | 1.36 | Effects of isoniazid and niacin on experimental wound-healing. ( Agren, MS; Beckert, S; Bilali, E; Coerper, S; Kleinman, HK; Königsrainer, A; Weinreich, J, 2010) |
Research
Studies (22)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Curran, CS | 1 |
| Kopp, JB | 1 |
| Peters, KM | 1 |
| Zhang, R | 1 |
| Park, C | 1 |
| Nong, Z | 1 |
| Yin, H | 1 |
| Wilson, RB | 1 |
| Sutherland, BG | 1 |
| Sawyez, CG | 1 |
| Pickering, JG | 1 |
| Borradaile, NM | 1 |
| Yasmeen, G | 1 |
| Dawani, ML | 1 |
| Mahboob, T | 1 |
| Weinreich, J | 1 |
| Agren, MS | 1 |
| Bilali, E | 1 |
| Kleinman, HK | 1 |
| Coerper, S | 1 |
| Königsrainer, A | 1 |
| Beckert, S | 1 |
| Huang, PH | 1 |
| Lin, CP | 1 |
| Wang, CH | 1 |
| Chiang, CH | 1 |
| Tsai, HY | 1 |
| Chen, JS | 1 |
| Lin, FY | 1 |
| Leu, HB | 1 |
| Wu, TC | 1 |
| Chen, JW | 1 |
| Lin, SJ | 1 |
| COSSIO, P | 1 |
| TANDOWSKY, RM | 1 |
| BUZZI, A | 2 |
| CIBEIRA, JB | 2 |
| NORMAND, J | 1 |
| CONDORELLI, L | 1 |
| NERISERNERI, GG | 1 |
| ROSSIFERRINI, PL | 1 |
| PAOLETTI, P | 1 |
| SILVESTRINI, E | 1 |
| PISKORZ, A | 1 |
| LEE, SS | 1 |
| WEBB, WR | 1 |
| Mullard, AJ | 1 |
| Reeves, MJ | 1 |
| Jacobs, BS | 1 |
| Kothari, RU | 1 |
| Birbeck, GL | 1 |
| Maddox, K | 1 |
| Stoeckle-Roberts, S | 1 |
| Wehner, S | 1 |
| Veryard, C | 1 |
| Warnick, CT | 1 |
| Lazarus, HM | 1 |
| Philipp, CS | 1 |
| Cisar, LA | 1 |
| Saidi, P | 1 |
| Kostis, JB | 1 |
| Henderson, HP | 1 |
| Hackett, ME | 1 |
| Holti, G | 1 |
| Dyson, A | 1 |
| Henderson, AM | 1 |
| Bomb, BS | 1 |
| Bedi, HK | 1 |
| Bhatnagar, LK | 1 |
Reviews
2 reviews available for niacin and Ischemia
| Article | Year |
|---|---|
The complexity of nicotinamide adenine dinucleotide (NAD), hypoxic, and aryl hydrocarbon receptor cell signaling in chronic kidney disease.
Topics: Basic Helix-Loop-Helix Transcription Factors; Humans; Hypoxia; Ischemia; NAD; Niacin; Receptors, Ary | 2023 |
The value of thermography in peripheral vascular disease.
Topics: Amputation, Surgical; Clinical Trials as Topic; Humans; Ischemia; Leg; Microcirculation; Niacin; Pla | 1978 |
Trials
4 trials available for niacin and Ischemia
| Article | Year |
|---|---|
Association of high-density lipoprotein cholesterol with improvement of endothelial dysfunction recovery in renovascular disease.
Topics: Adult; Atorvastatin; Biomarkers; Cholesterol, HDL; Delayed-Action Preparations; Drug Therapy, Combin | 2015 |
Effect of niacin supplementation on fibrinogen levels in patients with peripheral vascular disease.
Topics: Adult; Antioxidants; Arterial Occlusive Diseases; Cholesterol, HDL; Cholesterol, LDL; Dose-Response | 1998 |
The value of thermography in peripheral vascular disease.
Topics: Amputation, Surgical; Clinical Trials as Topic; Humans; Ischemia; Leg; Microcirculation; Niacin; Pla | 1978 |
Experimentally controlled evaluation of vasoactive drugs in digital ischemia.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cold Temperature; Double-Blind Method; Fingers; H | 1978 |
Other Studies
17 other studies available for niacin and Ischemia
| Article | Year |
|---|---|
Vitamin D intervention does not improve vascular regeneration in diet-induced obese male mice with peripheral ischemia.
Topics: Animals; Cell Movement; Cell Proliferation; Diet; Endothelial Cells; Gene Expression Profiling; Hind | 2019 |
Effects of isoniazid and niacin on experimental wound-healing.
Topics: Animals; Anti-Bacterial Agents; Cell Division; Ischemia; Isoniazid; Male; Niacin; Rats; Rats, Spragu | 2010 |
Niacin improves ischemia-induced neovascularization in diabetic mice by enhancement of endothelial progenitor cell functions independent of changes in plasma lipids.
Topics: Animals; Diabetes Mellitus, Experimental; Endothelial Cells; Flow Cytometry; In Situ Nick-End Labeli | 2012 |
The treatment of angina pectoris and other muscular pain due to ischemia with iproniazid and isoniazid.
Topics: Angina Pectoris; Humans; Iproniazid; Ischemia; Isoniazid; Niacin; Nicotinic Acids; Peripheral Vascul | 1958 |
Aluminum nicotinate combined with phenindione for relief of discomfort in peripheral vascular ischemia.
Topics: Aluminum; Ischemia; Ischium; Niacin; Nicotinic Acids; Phenindione; Vascular Diseases | 1962 |
[ACTION OF A VASODILATOR PREPARATION OF LOCAL EFFECT ON FUNCTIONAL VASCULOPATHIES AND THE POST POLIOMYELITIS PERNIO SYNDROME].
Topics: Body Temperature; Chilblains; Cyanosis; Humans; Ischemia; Niacin; Poliomyelitis; Raynaud Disease; Sk | 1963 |
[MEDICO-SURGICAL TREATMENT OF OBLITERATING ARTERIOPATHIES OF THE LOWER EXTREMITIES WITHOUT ACUTE ISCHEMIA. THE POINT OF VIEW OF THE PHYSICIAN].
Topics: Anticoagulants; Arteriosclerosis Obliterans; Autonomic Nerve Block; Embolism; Hypertonic Solutions; | 1964 |
[TREATMENT OF THE CUTANEOUS ISCHEMIA OF OCCLUSIVE ARTERIOSCLEROSIS OF THE EXTREMITIES WITH A VASODILATING PREPARATION OF LOCAL ACTION].
Topics: Amputees; Arteriosclerosis; Arteriosclerosis Obliterans; Body Temperature; Diabetes Mellitus; Humans | 1963 |
[ARTERIOLAR FUNCTIONAL DISORDERS IN OBLITERATING ARTERIOPATHIES].
Topics: Arteriosclerosis Obliterans; Blood Circulation; Drug Therapy; Electrocardiography; Humans; Intermitt | 1964 |
[RESEARCH ON INFLUENCE OF VASCULO-TISSUE FACTORS ON COAGULATION AND FIBRINOLYSIS. VI. LOCAL ACTIVATION AND GENERAL ACTIVATION OF FIBRINOLYSIS DIVERSITY OF RESPONSIBLE FACTORS].
Topics: Blood Coagulation; Fibrinolysis; Humans; Ischemia; Niacin; Nicotinic Acids; Thromboplastin | 1964 |
[TREATMENT OF ISCHEMIC DISTURBANCES WITHIN EXTREMITIES BY MEANS OF HEXOPAL ADMINISTRATION].
Topics: Drug Therapy; Inositol; Ischemia; Niacin; Nicotinic Acids; Vascular Diseases | 1965 |
Cardiac metabolism as influenced by ischemia, refrigeration, and enzyme precursors.
Topics: Enzyme Precursors; Heart Transplantation; Humans; Ischemia; Myocardium; Niacin; Nicotinic Acids; Ref | 1959 |
Lipid testing and lipid-lowering therapy in hospitalized ischemic stroke and transient ischemic attack patients: results from a statewide stroke registry.
Topics: Aged; Anticoagulants; Cholestyramine Resin; Clofibric Acid; Female; Hospital Records; Hospitalizatio | 2006 |
American Heart Association - Scientific Sessions 2006. Cell therapies for ischemic tissues and treatments for lipid metabolism disorders.
Topics: Animals; Cell- and Tissue-Based Therapy; Cholesterol, LDL; Coronary Disease; Endothelial Cells; Eryt | 2007 |
Protection from DNA damage during an ischemic cell injury.
Topics: Animals; DNA; DNA Repair; Ischemia; Kidney; Male; Mice; NAD; Niacin; Niacinamide | 1983 |
Continuous axillary brachial plexus blockade following intra-arterial injection of nicotinic acid.
Topics: Adult; Autonomic Nerve Block; Brachial Plexus; Bupivacaine; Hand; Humans; Injections, Intra-Arterial | 1987 |
Post-ischaemic paraesthesia in pellagrins.
Topics: Adolescent; Adult; Aged; Arm; Female; Humans; Ischemia; Male; Middle Aged; Paresthesia; Pellagra; Pe | 1977 |