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niacin and Huntington Disease

niacin has been researched along with Huntington Disease in 3 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harris, CA1
Miranda, AF1
Tanguay, JJ1
Boegman, RJ1
Beninger, RJ1
Jhamandas, K1
Puri, BK1
Hankes, LV1
Coenen, HH1
Rota, E1
Langen, KJ1
Herzog, H1
Wutz, W1
Stoecklin, G1
Feinendegen, LE1

Other Studies

3 other studies available for niacin and Huntington Disease

ArticleYear
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: Alanine; Animals; Anticonvulsants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism

1998
Impaired phospholipid-related signal transduction in advanced Huntington's disease.
    Experimental physiology, 2001, Volume: 86, Issue:5

    Topics: Adult; Female; Flushing; Humans; Huntington Disease; Male; Middle Aged; Niacin; Nicotinic Acids; Pho

2001
Effect of Huntington's and Alzheimer's diseases on the transport of nicotinic acid or nicotinamide across the human blood-brain barrier.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Alzheimer Disease; Blood-Brain Barrier; Brain; Humans; Huntington Disease; Niacin; Niacinamide; Tomo

1991