niacin has been researched along with Hematologic Malignancies in 1 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In mice, optimization of OT-82 dosing and dietary niacin further expanded the compound's therapeutic index." | 1.56 | OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis. ( Andrianova, EL; Antoch, MP; Chernov, MV; Chernova, OB; Gudkov, AV; Gupta, M; Haber, M; Henderson, MJ; Joshi, S; Kazyulkin, D; Komarov, PG; Kononov, E; Korotchkina, L; Krasnov, P; Lock, RB; Middlemiss, S; Norris, MD; Polinsky, A; Somers, K; Tian, Y; Toshkov, I; Veith, J; Vujcic, S, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Korotchkina, L | 1 |
| Kazyulkin, D | 1 |
| Komarov, PG | 1 |
| Polinsky, A | 1 |
| Andrianova, EL | 1 |
| Joshi, S | 1 |
| Gupta, M | 1 |
| Vujcic, S | 1 |
| Kononov, E | 1 |
| Toshkov, I | 1 |
| Tian, Y | 1 |
| Krasnov, P | 1 |
| Chernov, MV | 1 |
| Veith, J | 1 |
| Antoch, MP | 1 |
| Middlemiss, S | 1 |
| Somers, K | 1 |
| Lock, RB | 1 |
| Norris, MD | 1 |
| Henderson, MJ | 1 |
| Haber, M | 1 |
| Chernova, OB | 1 |
| Gudkov, AV | 1 |
1 other study available for niacin and Hematologic Malignancies
| Article | Year |
|---|---|
OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Proliferation; Cytokines; Female; Hemato | 2020 |