niacin has been researched along with Diabetes Mellitus, Type 1 in 16 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Low-dose niacin is a promising addition to hydroxymethylglutaryl-coenzyme A reductase inhibitor therapy in the treatment of hypercholesterolemia in patients with diabetes mellitus." | 5.08 | Combination of low-dose niacin and pravastatin improves the lipid profile in diabetic patients without compromising glycemic control. ( Fonseca, VA; Gardner, SF; Granberry, MC; Marx, MA; Skelton, DR; White, LM, 1997) |
| "Prediction of type 1a autoimmune diabetes can be established by a positive family history or by genetic, immunological or metabolic markers." | 2.47 | [Prediction and prevention of type 1 diabetes mellitus: initial results and recent prospects]. ( Madácsy, L, 2011) |
| "Combination treatment of stroke with BMSCs and Niaspan in T1DM rats increases white matter remodeling and additively increases BMSC monotherapy induced myelination and synaptic plasticity after stroke in T1DM rats." | 1.39 | Combination BMSC and Niaspan treatment of stroke enhances white matter remodeling and synaptic protein expression in diabetic rats. ( Chen, J; Chopp, M; Ning, R; Roberts, C; Venkat, P; Yan, T; Ye, X; Zacharek, A, 2013) |
| "Niaspan treatment of stroke increases vascular stabilization, decreases brain hemorrhage and blood-brain-barrier (BBB) leakage in T1DM rats." | 1.39 | Niaspan attenuates the adverse effects of bone marrow stromal cell treatment of stroke in type one diabetic rats. ( Chen, J; Chopp, M; Lu, M; Ning, R; Roberts, C; Venkat, P; Yan, T; Ye, X; Zacharek, A, 2013) |
| "Niacin treatment of PCN significantly increased Ang1 expression under high glucose condition." | 1.38 | Niaspan increases axonal remodeling after stroke in type 1 diabetes rats. ( Buller, B; Chen, J; Chopp, M; Cui, Y; Liu, Z; Roberts, C; Yan, T; Ye, X; Zacharek, A, 2012) |
| "Niaspan treatment of stroke in T1DM rats inhibits HMGB1/RAGE, TLR4 and MMP-9 expression which may contribute to the reduced inflammatory response after stroke in T1DM rats." | 1.37 | Niaspan reduces high-mobility group box 1/receptor for advanced glycation endproducts after stroke in type-1 diabetic rats. ( Chen, J; Chopp, M; Cui, X; Liu, X; Roberts, C; Yan, T; Ye, X; Zacharek, A, 2011) |
| "T1DM-rats were subjected to transient middle cerebral artery occlusion (MCAo) and treated without or with Niaspan." | 1.37 | Niaspan enhances vascular remodeling after stroke in type 1 diabetic rats. ( Chen, J; Chopp, M; Cui, X; Cui, Y; Liu, X; Lu, M; Roberts, C; Shehadah, A; Yan, T; Ye, X; Zacharek, A, 2011) |
| "Insulin resistance was induced by a 20-d continuous intravenous infusion of nicotinic acid (NA)." | 1.28 | Effect of nicotinic acid-induced insulin resistance on pancreatic B cell function in normal and streptozocin-treated baboons. ( Kahn, SE; Koerker, DJ; McCulloch, DK; Palmer, JP; Schwartz, MW, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ye, X | 5 |
| Yan, T | 5 |
| Chopp, M | 5 |
| Zacharek, A | 5 |
| Ning, R | 2 |
| Venkat, P | 2 |
| Roberts, C | 5 |
| Chen, J | 5 |
| Lu, M | 2 |
| McNamara, DB | 1 |
| Murthy, SN | 1 |
| Fonseca, AN | 1 |
| Desouza, CV | 1 |
| Kadowitz, PJ | 1 |
| Fonseca, VA | 2 |
| Gentile, V | 1 |
| Antonini, G | 1 |
| Antonella Bertozzi, M | 1 |
| Dinelli, N | 1 |
| Rizzo, C | 1 |
| Ashraf Virmani, M | 1 |
| Koverech, A | 1 |
| Liu, X | 2 |
| Cui, X | 2 |
| Cui, Y | 2 |
| Shehadah, A | 1 |
| Madácsy, L | 1 |
| Liu, Z | 1 |
| Buller, B | 1 |
| Gambhir, D | 1 |
| Ananth, S | 1 |
| Veeranan-Karmegam, R | 1 |
| Elangovan, S | 1 |
| Hester, S | 1 |
| Jennings, E | 1 |
| Offermanns, S | 1 |
| Nussbaum, JJ | 1 |
| Smith, SB | 1 |
| Thangaraju, M | 1 |
| Ganapathy, V | 1 |
| Martin, PM | 1 |
| Packard, C | 1 |
| Olsson, AG | 1 |
| ROGOZINSKI, R | 1 |
| Gardner, SF | 1 |
| Marx, MA | 1 |
| White, LM | 1 |
| Granberry, MC | 1 |
| Skelton, DR | 1 |
| Hannan, F | 1 |
| Davoren, P | 1 |
| McCulloch, DK | 1 |
| Kahn, SE | 1 |
| Schwartz, MW | 1 |
| Koerker, DJ | 1 |
| Palmer, JP | 1 |
| Hale, PJ | 1 |
| Nattrass, M | 1 |
| Ajjam, ZS | 1 |
| Barton, S | 1 |
| Corbett, M | 1 |
| Owens, D | 1 |
| Marks, R | 1 |
3 reviews available for niacin and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Animal models of catheter-induced intimal hyperplasia in type 1 and type 2 diabetes and the effects of pharmacologic intervention.
Topics: Animals; Biguanides; Catheterization; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Di | 2009 |
[Prediction and prevention of type 1 diabetes mellitus: initial results and recent prospects].
Topics: Autoantibodies; Biomarkers; Diabetes Mellitus, Type 1; Enterovirus Infections; Genetic Predispositio | 2011 |
Management of hypercholesterolaemia in the patient with diabetes.
Topics: Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Diabetes Mellitus, T | 2002 |
2 trials available for niacin and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Effect of propionyl-L-carnitine, L-arginine and nicotinic acid on the efficacy of vardenafil in the treatment of erectile dysfunction in diabetes.
Topics: Arginine; Carnitine; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Erectile Dysfunction; Hum | 2009 |
Combination of low-dose niacin and pravastatin improves the lipid profile in diabetic patients without compromising glycemic control.
Topics: Adult; Aged; Anticholesteremic Agents; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 1; D | 1997 |
11 other studies available for niacin and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Combination BMSC and Niaspan treatment of stroke enhances white matter remodeling and synaptic protein expression in diabetic rats.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Lipoproteins, HDL; Mesen | 2013 |
Niaspan attenuates the adverse effects of bone marrow stromal cell treatment of stroke in type one diabetic rats.
Topics: Animals; Blood-Brain Barrier; Diabetes Mellitus, Type 1; Disease Models, Animal; Ectodysplasins; Int | 2013 |
Niaspan reduces high-mobility group box 1/receptor for advanced glycation endproducts after stroke in type-1 diabetic rats.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; HMGB Proteins; Male; Nia | 2011 |
Niaspan enhances vascular remodeling after stroke in type 1 diabetic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Blood-Brain Barrier; Cerebral Hemorrhage; Cer | 2011 |
Niaspan increases axonal remodeling after stroke in type 1 diabetes rats.
Topics: Animals; Axons; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Infarction, Middle Cerebr | 2012 |
GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
Topics: 3-Hydroxybutyric Acid; Aged; Animals; Cell Line; Chemokine CCL2; Diabetes Mellitus, Experimental; Di | 2012 |
[EFFECT OF SOME VITAMINS FROM THE B GROUP AND OF COCARBOXYLASE ON THE BLOOD SUGAR CURVE IN JUVENILE DIABETES MELLITUS].
Topics: Adolescent; Blood Glucose; Diabetes Mellitus, Type 1; Folic Acid; Humans; Niacin; Niacinamide; Pharm | 1963 |
Use of nicotinic acid in the management of recurrent hypoglycemic episodes in diabetes.
Topics: Blood Glucose; Chronic Disease; Diabetes Mellitus, Type 1; Female; Humans; Hypoglycemia; Insulin; Mi | 2001 |
Effect of nicotinic acid-induced insulin resistance on pancreatic B cell function in normal and streptozocin-treated baboons.
Topics: Animals; Arginine; Diabetes Mellitus, Type 1; Fasting; Glucose; Insulin; Insulin Resistance; Islets | 1991 |
The short-term effect of nicotinic acid on intermediary metabolism in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Humans; Insul | 1991 |
Quantitative evaluation of the dermal vasculature of diabetics.
Topics: Adult; Aged; Benzocaine; Biometry; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathi | 1985 |