niacin has been researched along with Dementia in 33 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niacin or tryptophan deficiency causes pellagra." | 8.02 | A peculiarly characterised case of isoniazid-induced pellagra- 2 Ds and a C: a case report. ( Kabengele, C; M'hango, H; Malumani, M; Mweemba, D, 2021) |
| "Nicergoline (NE)--a cerebral vasodilator with nicotinic acid esterified in its molecule--and Antagonic-Stress (AS) composition--a neurometabolic nootropic, also containing nicotinic acid but with fast and prolonged release--were evaluated in senile dementia of Alzheimer's type (SDAT), mild to moderate intensity (DSM-IV Options Book, 1991 and ICD-10, 1990 criteria)." | 5.07 | Superiority of antagonic-stress composition versus nicergoline in gerontopsychiatry. ( Mateescu, R; Măties, R; Mihalas, G; Mihalas, IG; Popa, R; Schneider, F; Stefanigă, P, 1994) |
| "Niacin or tryptophan deficiency causes pellagra." | 4.02 | A peculiarly characterised case of isoniazid-induced pellagra- 2 Ds and a C: a case report. ( Kabengele, C; M'hango, H; Malumani, M; Mweemba, D, 2021) |
| "Pellagra, caused by vitamin B3 (niacin) deficiency, is traditionally described as dermatitis, diarrhea, dementia (3D), and even death (4D) syndrome if not recognized and treated promptly." | 3.96 | Pellagra, an Almost-Forgotten Differential Diagnosis of Chronic Diarrhea: More Prevalent Than We Think. ( Cao, S; Cestodio, K; Wang, X, 2020) |
| "AbstractPellagra is a deficiency of niacin or its amino acid precursor, tryptophan, which presents with the classic four Ds: the characteristic dermatitis, diarrhea, dementia, and eventually death if left untreated." | 3.85 | An Outbreak of Pellagra in the Kasese Catchment Area, Dowa, Malawi. ( Dunn, SH; Matapandeu, G; Pagels, P, 2017) |
| " We report a patient with Wernicke encephalopathy, a B1 deficiency and pellagra, a niacin deficiency." | 3.81 | Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient. ( Kinoshita, K; Taguchi, S; Terada, N; Tokuda, Y, 2015) |
| " The disease is caused by a deficiency of niacin and is clinically characterized by the triad of dermatitis, diarrhoea and dementia." | 3.78 | Pellagra: a non-communicable disease of poverty. ( Chamdula, A; Frank, GP; Koop, K; van Oosterhout, JJ; Voorend, DM, 2012) |
| "However, cases of pellagra are recently reported in West Europe, USA, Australia, and Japan in connection with chronic alcoholism, gastrointestinal malabsorption, and some medications." | 1.35 | The diagnostic importance of photosensitivity dermatoses in chronic alcoholism: report of two cases. ( Cholongitas, E; Ioannidou, D; Pipili, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (42.42) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 6 (18.18) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 3 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, S | 1 |
| Wang, X | 1 |
| Cestodio, K | 1 |
| Kabengele, C | 1 |
| M'hango, H | 1 |
| Mweemba, D | 1 |
| Malumani, M | 1 |
| Terada, N | 1 |
| Kinoshita, K | 1 |
| Taguchi, S | 1 |
| Tokuda, Y | 1 |
| Matapandeu, G | 1 |
| Dunn, SH | 1 |
| Pagels, P | 1 |
| Pipili, C | 1 |
| Cholongitas, E | 1 |
| Ioannidou, D | 1 |
| Frank, GP | 1 |
| Voorend, DM | 1 |
| Chamdula, A | 1 |
| van Oosterhout, JJ | 1 |
| Koop, K | 1 |
| DYMLING, A | 1 |
| ECKERSTROM, S | 1 |
| NORDMAN, LO | 1 |
| ERWIN, HJ | 2 |
| JOHNSON, FG | 1 |
| PROCTOR, RC | 1 |
| BAILEY, WH | 1 |
| MOREHOUSE, WG | 1 |
| CLARKE, ET | 1 |
| KUNERT, W | 1 |
| DUNKER, R | 1 |
| HOFFER, A | 1 |
| Bryan, CS | 1 |
| Koga, H | 1 |
| Yuzuriha, T | 1 |
| GREGORY, I | 1 |
| Moriwaka, F | 1 |
| Schneider, F | 1 |
| Popa, R | 1 |
| Mihalas, G | 1 |
| Stefanigă, P | 1 |
| Mihalas, IG | 1 |
| Măties, R | 1 |
| Mateescu, R | 1 |
| Dormehl, IC | 1 |
| Jordaan, B | 1 |
| Oliver, DW | 1 |
| Croft, S | 1 |
| Ishikawa, Y | 1 |
| Zhang, Q | 1 |
| Man, X | 1 |
| Wang, W | 1 |
| Tang, S | 1 |
| Wang, Y | 1 |
| Feng, Y | 1 |
| Du, Y | 1 |
| Cong, L | 1 |
| Dalla, A | 1 |
| Kumar, S | 1 |
| De, D | 1 |
| Kapoor, R | 1 |
| Saint, S | 1 |
| Kapoor, JR | 1 |
| Johnson, RA | 1 |
| Dhaliwal, G | 1 |
| Wilcox, LS | 1 |
| Kapas, I | 1 |
| Majtenyi, K | 1 |
| Törö, K | 1 |
| Keller, E | 1 |
| Voigtländer, T | 1 |
| Kovacs, GG | 1 |
| JACOB, H | 1 |
| KIØRBOE, E | 1 |
| VINTHER-PAULSEN, N | 1 |
| Hampl, JS | 1 |
| Hampl, WS | 1 |
| Abe, Y | 1 |
| Nishino, S | 1 |
| Takahashi, M | 1 |
| Furuya, R | 1 |
| Imura, K | 1 |
| Mori, K | 1 |
| Takahashi, H | 1 |
| Yoshiya, K | 1 |
| Tassies, MD | 1 |
| Estruch, R | 1 |
| Ribalta, T | 1 |
| Molina Arjona, JA | 1 |
| Gomara López, S | 1 |
| Bermejo Pareja, F | 1 |
| Rodríguez Vallejo, J | 1 |
| Cabello, A | 1 |
| Morales Otal, MA | 1 |
| Ban, TA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077] | 70 participants (Anticipated) | Interventional | 2022-05-14 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for niacin and Dementia
| Article | Year |
|---|---|
[Pellagra's encephalopathy].
Topics: Alcoholism; Brain; Dementia; Dermatitis; Diarrhea; Fatal Outcome; Humans; Male; Middle Aged; Niacin; | 2003 |
[Nicotinic acid].
Topics: Dementia; Dermatitis; Diagnosis, Differential; Diarrhea; Humans; Niacin; Niacinamide; Pellagra; Synd | 2004 |
[Niacin deficiency disease(pellagra)].
Topics: Alcoholism; Dementia; Dermatitis; Diagnosis, Differential; Diarrhea; Humans; Isoniazid; Niacin; Pell | 2000 |
Nicotinic acid and psychiatry.
Topics: Aged; Anxiety; Avitaminosis; Brain Diseases; Child; Child, Preschool; Clinical Trials as Topic; Deme | 1971 |
3 trials available for niacin and Dementia
| Article | Year |
|---|---|
Superiority of antagonic-stress composition versus nicergoline in gerontopsychiatry.
Topics: Aged; Aging; Dementia; Double-Blind Method; Drug Combinations; Female; Geriatric Assessment; Humans; | 1994 |
SPECT monitoring of improved cerebral blood flow during long-term treatment of elderly patients with nootropic drugs.
Topics: Administration, Oral; Aged; Aging; Brain; Cerebellum; Cerebrovascular Circulation; Cognition; Cross- | 1999 |
Nicotinic acid and psychiatry.
Topics: Aged; Anxiety; Avitaminosis; Brain Diseases; Child; Child, Preschool; Clinical Trials as Topic; Deme | 1971 |
27 other studies available for niacin and Dementia
| Article | Year |
|---|---|
Pellagra, an Almost-Forgotten Differential Diagnosis of Chronic Diarrhea: More Prevalent Than We Think.
Topics: Aged, 80 and over; Alcoholism; Dementia; Dermatitis; Diagnosis, Differential; Diarrhea; Humans; Male | 2020 |
A peculiarly characterised case of isoniazid-induced pellagra- 2 Ds and a C: a case report.
Topics: Adult; Anti-HIV Agents; Antitubercular Agents; Constipation; Dementia; Dermatitis; Female; HIV Infec | 2021 |
Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient.
Topics: Alcoholism; Confusion; Dementia; Dermatitis; Diarrhea; Humans; Magnetic Resonance Imaging; Male; Mid | 2015 |
An Outbreak of Pellagra in the Kasese Catchment Area, Dowa, Malawi.
Topics: Adolescent; Adult; Dementia; Dermatitis; Diarrhea; Dietary Supplements; Disease Outbreaks; Female; H | 2017 |
The diagnostic importance of photosensitivity dermatoses in chronic alcoholism: report of two cases.
Topics: Alcoholism; Combined Modality Therapy; Dementia; Diabetes Complications; Glossitis; Greece; Humans; | 2008 |
Pellagra: a non-communicable disease of poverty.
Topics: Adult; Aged; Dementia; Dermatitis; Diarrhea; Female; Humans; Malawi; Male; Niacin; Pellagra; Poverty | 2012 |
[Experience with stimulative therapy in mental disorders in aged].
Topics: Amides; Anesthetics, Local; Dementia; Mental Disorders; Niacin; Nicotinic Acids; Psychotic Disorders | 1956 |
Reversible symptoms in senile psychosis.
Topics: Dementia; Electroconvulsive Therapy; Mental Disorders; Niacin; Nicotinic Acids; Psychotic Disorders; | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
Evaluation of nicozol in the care of the senile psychotic.
Topics: Dementia; Humans; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1957 |
An analeptic tranquilizer for senile psychoses; report of clinical and pharmacological studies of nicozol with reserpine.
Topics: Central Nervous System Stimulants; Dementia; Mental Disorders; Niacin; Pentylenetetrazole; Psychotic | 1958 |
Observations on Benizol therapy in general practice. Ninety senile patients.
Topics: Arteriosclerosis; Dementia; General Practice; Geriatrics; Humans; Niacin; Nicotinic Acids; Pentylene | 1962 |
[ON ELECTRORHEOGRAPHIC OBJECTIVE EVALUATION OF SUBSTANCES WITH CENTRAL NERVOUS SYSTEM ACTION. SODIUM NICOTINATE AND SODIUM BETA,BETA-PENTAMETHYLENE-GAMMA-HYDROXYBUTYRATE MONOHYDRATE].
Topics: 3-Hydroxybutyric Acid; Cerebrovascular Circulation; Dementia; Drug Therapy; Electric Impedance; Elec | 1963 |
TREATMENT OF ORGANIC PSYCHOSIS WITH NICOTINIC ACID. (A SINGLE CASE).
Topics: Ascorbic Acid; Brain; Brain Damage, Chronic; Carcinoma, Bronchogenic; Dementia; Diagnosis, Different | 1965 |
Pellagra in South Carolina: déjà vu.
Topics: Deja Vu; Dementia; History, 20th Century; Humans; Niacin; Pellagra; South Carolina | 2003 |
Nicotinic acid therapy in psychoses of senility.
Topics: Dementia; Humans; Mental Disorders; Niacin; Nicotinic Acids; Psychotic Disorders | 1952 |
A case of alcoholic pellagra presenting with dementia and polyneuropathy.
Topics: Alcoholism; Dementia; Humans; Pellagra; Polyneuropathies | 2022 |
Elderly patient of Crohn's disease with dementia and edematous red plaques on dorsum of hands.
Topics: Aged; Crohn Disease; Dementia; Diarrhea; Exanthema; Hand; Humans; Male; Pellagra | 2019 |
Clinical problem-solving. D is for delay.
Topics: Clostridioides difficile; Clostridium Infections; Delayed Diagnosis; Dementia; Dermatitis; Diagnosis | 2014 |
Worms and germs, drink and dementia: US health, society, and policy in the early 20th century.
Topics: Alcohol Drinking; Communicable Disease Control; Dementia; Health Policy; History, 20th Century; Hook | 2008 |
Pellagra encephalopathy as a differential diagnosis for Creutzfeldt-Jakob disease.
Topics: 14-3-3 Proteins; Adult; Aged; Aged, 80 and over; Brain; Creutzfeldt-Jakob Syndrome; Dementia; Diagno | 2012 |
[The differential diagnosis of pernicious involutional psychoses, presenile psychoses and psychoses in involutional pellagra. On the problem of endogenous-exogenous mixed forms (intermediate syndrome) in old age].
Topics: Aged; Aged, 80 and over; Aging; Dementia; Depressive Disorder, Major; Diagnosis, Differential; Human | 1960 |
[Senile psychosis and pellagra].
Topics: Dementia; Folic Acid; Humans; Pellagra; Psychotic Disorders; Vitamin B Complex | 1950 |
Pellagra and the origin of a myth: evidence from European literature and folklore.
Topics: Death; Dementia; Dermatitis; Diarrhea; History, 19th Century; Humans; Medicine in Literature; Mythol | 1997 |
[A case of pellagra manifested by various symptoms].
Topics: Dementia; Dermatitis; Diarrhea; Female; Humans; Middle Aged; Nicotinic Acids; Pellagra; Peripheral N | 1990 |
[Pellagroid encephalopathy in chronic alcoholism: diagnostic difficulties].
Topics: Alcoholism; Brain Diseases; Dementia; Female; Humans; Middle Aged; Pellagra | 1989 |
[Neurological manifestations of pellagra: description of 2 cases].
Topics: Adult; Aged; Alcoholism; Brain; Brain Diseases; Dementia; Female; Humans; Male; Pellagra; Skin | 1985 |