niacin has been researched along with Constitutional Liver Dysfunction in 14 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperbilirubinemia in Gilbert syndrome can be caused not only inhibition of bilirubin-glucuronidation in the liver but also defective uptake of bilirubin by hepatocytes." | 1.31 | [Gilbert's syndrome: pathogenesis and diagnosis]. ( Goncharik, II; Kravchenko, IuS, 2001) |
| "It is of no value in differentiating Gilbert's syndrome from liver disease." | 1.28 | The nicotinic acid provocation test and unconjugated hyperbilirubinaemia. ( Callender, ME; Dickey, W; McAleer, JJ, 1991) |
| "In 42 young adults with Gilbert's syndrome and in 9 patients with inactive, well-compensated liver cirrhosis the peroral nicotinic acid test was performed." | 1.28 | The nicotinic acid test in the evaluation of unconjugated hyperbilirubinemia. ( Horák, J; Kostihová, E; Mertl, L; Pokorná, B; Trunecka, P, 1989) |
| "A case of postoperative jaundice due to Gilbert's syndrome in a previously healthy 19-year-old female is presented." | 1.27 | Gilbert's syndrome as a cause of postoperative jaundice. ( Taylor, S, 1984) |
| "the well-known hyperbilirubinemia; 2." | 1.27 | Hypersideremic and hyperbilirubinemic effect of nicotinic acid in patients with Gilbert's syndrome. ( Gentile, F; Gentile, S, 1987) |
| "This effect is higher in Gilbert's syndrome (GS) and this test has been used in the diagnosis of the syndrome." | 1.27 | Sex differences of nicotinate-induced hyperbilirubinemia in Gilbert's syndrome. Implication of bilitranslocase function. ( Baldini, G; Gentile, S; Lunazzi, G; Sottocasa, GL; Tiribelli, C, 1985) |
| "The peak incidence of Gilbert's syndrome was in the 15-30 years age group with males predominating almost fivefold." | 1.26 | [Positive diagnosis of Gilbert syndrome. Retrospective analysis of 59 cases with special reference to the nicotinic acid test]. ( Bircher, J; Preisig, D; Preisig, R, 1982) |
| "Five patients with Gilbert's syndrome had normal serum bilirubin concentrations (less than 17." | 1.26 | Nicotinic acid test in the diagnosis of Gilbert's syndrome: correlation with bilirubin clearance. ( Paumgartner, G; Preisig, R; Röllinghoff, W, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taylor, S | 1 |
| Gentile, S | 5 |
| Marmo, R | 3 |
| Persico, M | 3 |
| Bronzino, P | 3 |
| Coltorti, M | 2 |
| Preisig, D | 1 |
| Bircher, J | 1 |
| Preisig, R | 2 |
| Röllinghoff, W | 1 |
| Paumgartner, G | 1 |
| Goncharik, II | 1 |
| Kravchenko, IuS | 1 |
| Dickey, W | 1 |
| McAleer, JJ | 1 |
| Callender, ME | 1 |
| Horák, J | 1 |
| Pokorná, B | 1 |
| Mertl, L | 1 |
| Kostihová, E | 1 |
| Trunecka, P | 1 |
| Fengler, JD | 2 |
| Markus, R | 2 |
| Spallek, E | 2 |
| Eike, O | 2 |
| Baumgarten, R | 2 |
| Gentile, F | 1 |
| Tiribelli, C | 2 |
| Baldini, G | 1 |
| Lunazzi, G | 1 |
| Sottocasa, GL | 1 |
| Orzes, N | 1 |
| Orlando, C | 1 |
| Rubba, P | 2 |
| Pérez Blanco, FJ | 1 |
| Martín Ruíz, JL | 1 |
| Caballero Plasencia, A | 1 |
| González Calvín, J | 1 |
| Montero García, M | 1 |
| Peña Angulo, JF | 1 |
| Faccenda, F | 1 |
14 other studies available for niacin and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
Gilbert's syndrome as a cause of postoperative jaundice.
Topics: Adult; Anesthesia; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Jaundice; Niacin | 1984 |
Plasma clearance of nicotinic acid and rifamycin-SV, and their interaction in Gilbert's syndrome: application of a compartmental model.
Topics: Adolescent; Adult; Drug Interactions; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditar | 1984 |
[Positive diagnosis of Gilbert syndrome. Retrospective analysis of 59 cases with special reference to the nicotinic acid test].
Topics: Acetylation; Adolescent; Adult; Bilirubin; Child; Female; Gilbert Disease; Humans; Hyperbilirubinemi | 1982 |
Nicotinic acid test in the diagnosis of Gilbert's syndrome: correlation with bilirubin clearance.
Topics: Adult; Bilirubin; Erythrocyte Aging; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary | 1981 |
[Gilbert's syndrome: pathogenesis and diagnosis].
Topics: Bilirubin; Biopsy; Female; Gilbert Disease; Humans; Liver; Male; Middle Aged; Niacin; Radiography; R | 2001 |
The nicotinic acid provocation test and unconjugated hyperbilirubinaemia.
Topics: Bilirubin; Chronic Disease; Gilbert Disease; Humans; Hyperbilirubinemia; Injections, Intravenous; Li | 1991 |
The nicotinic acid test in the evaluation of unconjugated hyperbilirubinemia.
Topics: Administration, Oral; Adolescent; Adult; Bilirubin; Diagnosis, Differential; Female; Gilbert Disease | 1989 |
[The Gilbert-Meulengracht syndrome--diagnosis and management in the physician's practice].
Topics: Adolescent; Adult; Bilirubin; Diagnosis, Differential; Female; Follow-Up Studies; Gilbert Disease; H | 1989 |
[Rational diagnosis of functional hyperbilirubinemia and management of patients with Gilbert-Meulengracht syndrome].
Topics: Adolescent; Adult; Bilirubin; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Liver | 1987 |
Hypersideremic and hyperbilirubinemic effect of nicotinic acid in patients with Gilbert's syndrome.
Topics: Adolescent; Adult; Gilbert Disease; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Iron | 1987 |
Sex differences of nicotinate-induced hyperbilirubinemia in Gilbert's syndrome. Implication of bilitranslocase function.
Topics: Adolescent; Adult; Animals; Bilirubin; Binding, Competitive; Ceruloplasmin; Female; Gilbert Disease; | 1985 |
Dose dependence of nicotinic acid-induced hyperbilirubinemia and its dissociation from hemolysis in Gilbert's syndrome.
Topics: Adolescent; Adult; Anemia, Hemolytic; Bilirubin; Dose-Response Relationship, Drug; Female; Gilbert D | 1986 |
[The nicotinic acid and rifampicin tests in Gilbert's syndrome].
Topics: Adult; Bilirubin; Evaluation Studies as Topic; Female; Gilbert Disease; Humans; Hyperbilirubinemia, | 1985 |
Improvement of the nicotinic acid test in the diagnosis of Gilbert's syndrome by pretreatment with indomethacin.
Topics: Adolescent; Adult; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Indomethacin; Ma | 1985 |