niacin has been researched along with Colonic Neoplasms in 9 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reexpression of GPR109A in colon cancer cells induces apoptosis, but only in the presence of its ligands butyrate and nicotinate." | 1.35 | GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. ( Ananth, S; Browning, DD; Cresci, GA; Digby, GJ; Ganapathy, V; Gnanaprakasam, JP; Lambert, NA; Liu, K; Mellinger, JD; Prasad, PD; Smith, SB; Thangaraju, M, 2009) |
| "The incidence of colon cancer is high in many developed nations, especially New Zealand." | 1.32 | Epigenetic events and protection from colon cancer in New Zealand. ( Ferguson, LR; Karunasinghe, N; Philpott, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, J | 2 |
| Lee, J | 1 |
| Oh, JH | 1 |
| Sohn, DK | 1 |
| Shin, A | 1 |
| Chang, HJ | 1 |
| Sen, U | 1 |
| Shenoy P, S | 1 |
| Bose, B | 1 |
| Singh, N | 1 |
| Gurav, A | 1 |
| Sivaprakasam, S | 1 |
| Brady, E | 1 |
| Padia, R | 1 |
| Shi, H | 1 |
| Thangaraju, M | 2 |
| Prasad, PD | 2 |
| Manicassamy, S | 1 |
| Munn, DH | 1 |
| Lee, JR | 1 |
| Offermanns, S | 1 |
| Ganapathy, V | 2 |
| Kim, SW | 1 |
| Lee, JH | 2 |
| Moon, JH | 1 |
| Nazim, UM | 1 |
| Lee, YJ | 1 |
| Seol, JW | 1 |
| Hur, J | 1 |
| Eo, SK | 1 |
| Park, SY | 1 |
| Cresci, GA | 1 |
| Liu, K | 1 |
| Ananth, S | 1 |
| Gnanaprakasam, JP | 1 |
| Browning, DD | 1 |
| Mellinger, JD | 1 |
| Smith, SB | 1 |
| Digby, GJ | 1 |
| Lambert, NA | 1 |
| Beauparlant, P | 1 |
| Bédard, D | 1 |
| Bernier, C | 1 |
| Chan, H | 1 |
| Gilbert, K | 1 |
| Goulet, D | 1 |
| Gratton, MO | 1 |
| Lavoie, M | 1 |
| Roulston, A | 1 |
| Turcotte, E | 1 |
| Watson, M | 1 |
| Ferguson, LR | 1 |
| Karunasinghe, N | 1 |
| Philpott, M | 1 |
| Shi, J | 1 |
| Jia, B | 1 |
| Liu, Z | 1 |
| Yang, Z | 1 |
| Yu, Z | 1 |
| Chen, K | 1 |
| Chen, X | 1 |
| Liu, S | 1 |
| Wang, F | 1 |
| Newmark, HL | 1 |
| Heaney, RP | 1 |
| Lachance, PA | 1 |
9 other studies available for niacin and Colonic Neoplasms
| Article | Year |
|---|---|
Dietary methyl donor nutrients, DNA mismatch repair polymorphisms, and risk of colorectal cancer based on microsatellite instability status.
Topics: Case-Control Studies; Choline; Colonic Neoplasms; Colorectal Neoplasms; Diet; DNA Mismatch Repair; F | 2022 |
Opposing effects of low versus high concentrations of water soluble vitamins/dietary ingredients Vitamin C and niacin on colon cancer stem cells (CSCs).
Topics: Animals; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relat | 2017 |
Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.
Topics: Animals; Butyrates; Carcinogenesis; Cell Differentiation; Cells, Cultured; Colitis; Colon; Colonic N | 2014 |
Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation.
Topics: Apoptosis; Autophagy; Blotting, Western; Cell Proliferation; Colonic Neoplasms; Flow Cytometry; Fluo | 2016 |
GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.
Topics: Amino Acid Sequence; Animals; Apoptosis; Butyrates; Colon; Colonic Neoplasms; DNA Methylation; Ferme | 2009 |
Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Line, Tumor; Colonic Neo | 2009 |
Epigenetic events and protection from colon cancer in New Zealand.
Topics: Alcohol Drinking; Colonic Neoplasms; Dietary Fiber; DNA Methylation; Folic Acid; Genistein; Humans; | 2004 |
99mTc-labeled bombesin(7-14)NH2 with favorable properties for SPECT imaging of colon cancer.
Topics: Amino Acid Sequence; Animals; Bombesin; Colonic Neoplasms; Cross-Linking Reagents; Gastrin-Releasing | 2008 |
Should calcium and vitamin D be added to the current enrichment program for cereal-grain products?
Topics: Adolescent; Adult; Aged; Calcium, Dietary; Child; Colonic Neoplasms; Edible Grain; Female; Food, For | 2004 |