Page last updated: 2024-10-19

niacin and Colitis

niacin has been researched along with Colitis in 12 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
" The current study aimed to investigate the potential impact of niacin on colitis-induced depressive-like behavior in rats."8.31Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms. ( Abd El-Haleim, EA; Khayyal, MT; Mohamed, SS; Wadie, W, 2023)
"Uniformly good response to isoniazid therapy was observed in five cases of chronic ulcerative colitis during an initial period of 3 to 6 months of treatment."7.63Isoniazid therapy in chronic ulcerative colitis; a preliminary report. ( SUSNOW, DA, 1954)
" The current study aimed to investigate the potential impact of niacin on colitis-induced depressive-like behavior in rats."4.31Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms. ( Abd El-Haleim, EA; Khayyal, MT; Mohamed, SS; Wadie, W, 2023)
"Hydroxycarboxylic acid receptor 2 (HCAR2), modulated by endogenous ketone body β-hydroxybutyrate and exogenous niacin, is a promising therapeutic target for inflammation-related diseases."4.31Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation. ( Cheng, L; Fu, H; Fu, P; Hu, H; Li, Z; Liu, Y; Ma, L; Shao, Z; Shen, C; Tian, X; Wang, B; Wang, C; Wang, H; Wu, C; Yan, W; Yang, S; Yu, J; Zhao, C, 2023)
"Uniformly good response to isoniazid therapy was observed in five cases of chronic ulcerative colitis during an initial period of 3 to 6 months of treatment."3.63Isoniazid therapy in chronic ulcerative colitis; a preliminary report. ( SUSNOW, DA, 1954)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's2 (16.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Wadie, W1
Mohamed, SS1
Abd El-Haleim, EA1
Khayyal, MT1
Zhao, C1
Wang, H1
Liu, Y1
Cheng, L1
Wang, B1
Tian, X1
Fu, H1
Wu, C1
Li, Z1
Shen, C1
Yu, J1
Yang, S1
Hu, H1
Fu, P1
Ma, L1
Wang, C1
Yan, W1
Shao, Z1
Singh, N1
Gurav, A1
Sivaprakasam, S1
Brady, E1
Padia, R1
Shi, H1
Thangaraju, M1
Prasad, PD1
Manicassamy, S1
Munn, DH1
Lee, JR1
Offermanns, S1
Ganapathy, V1
Graff, EC1
Fang, H1
Wanders, D1
Judd, RL1
SUSNOW, DA1
WEILLER, P1
SAMITZ, MH1
RAMZY, I1
Lu, JY1
Yu, CL1
Wu, MZ1
Clayton, PT1
Bridges, NA1
Atherton, DJ1
Milla, PJ1
Malone, M1
Bender, DA1
Segal, I1
Ou Tim, L1
Demetriou, A1
Paterson, A1
Hale, M1
Lerios, M1

Reviews

1 review available for niacin and Colitis

ArticleYear
Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2.
    Metabolism: clinical and experimental, 2016, Volume: 65, Issue:2

    Topics: Animals; Atherosclerosis; Colitis; Diabetic Retinopathy; Humans; Inflammation; Mice; Neoplasms; Neur

2016

Other Studies

11 other studies available for niacin and Colitis

ArticleYear
Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms.
    Life sciences, 2023, Oct-01, Volume: 330

    Topics: Animals; Benzilates; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Niacin; Rat

2023
Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
    Molecular cell, 2023, 09-07, Volume: 83, Issue:17

    Topics: Allosteric Regulation; Animals; Colitis; GTP-Binding Protein alpha Subunits, Gi-Go; Inflammation; Ke

2023
Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.
    Immunity, 2014, Jan-16, Volume: 40, Issue:1

    Topics: Animals; Butyrates; Carcinogenesis; Cell Differentiation; Cells, Cultured; Colitis; Colon; Colonic N

2014
Isoniazid therapy in chronic ulcerative colitis; a preliminary report.
    California medicine, 1954, Volume: 81, Issue:2

    Topics: Colitis; Colitis, Ulcerative; Humans; Isoniazid; Niacin; Nicotinic Acids

1954
[Use of isoniazid in therapy of painful colitis of the ileocecal region].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1955, Volume: 44, Issue:3

    Topics: Colitis; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pain

1955
[Some apparently unusual secondary effects of isonicotinic acid hydrazide on the digestive tract].
    Le Poumon et le coeur, 1955, Volume: 11, Issue:3

    Topics: Colitis; Constipation; Gastrointestinal Tract; Humans; Isoniazid; Niacin; Nicotinic Acids; Peptic Ul

1955
SKIN MANIFESTATIONS OF GASTROINTESTINAL DISEASES. I.
    Skin, 1963, Volume: 2

    Topics: Celiac Disease; Colitis; Colitis, Ulcerative; Dermatology; Gastroenterology; Gastrointestinal Diseas

1963
COLITIS GLANDULARIS CYSTICA; (CASE REPORT).
    The Journal of the Egyptian Medical Association, 1964, Volume: 47

    Topics: Colitis; Colonic Diseases; Cysts; Humans; Pathology; Pellagra; Schistosomiasis

1964
Pellagra in an immunocompetent patient with cytomegalovirus colitis.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:3

    Topics: Colitis; Cytomegalovirus Infections; Humans; Immunocompetence; Male; Middle Aged; Pellagra

2001
Pellagra with colitis due to a defect in tryptophan metabolism.
    European journal of pediatrics, 1991, Volume: 150, Issue:7

    Topics: Child; Colitis; Female; Humans; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Niacinamide;

1991
Rectal manifestations of pellagra.
    International journal of colorectal disease, 1986, Volume: 1, Issue:4

    Topics: Adult; Aged; Colitis; Colonic Diseases; Diarrhea; Female; Humans; Male; Middle Aged; Pellagra; Skin

1986