niacin has been researched along with Colitis in 12 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Excerpt | Relevance | Reference |
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" The current study aimed to investigate the potential impact of niacin on colitis-induced depressive-like behavior in rats." | 8.31 | Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms. ( Abd El-Haleim, EA; Khayyal, MT; Mohamed, SS; Wadie, W, 2023) |
"Uniformly good response to isoniazid therapy was observed in five cases of chronic ulcerative colitis during an initial period of 3 to 6 months of treatment." | 7.63 | Isoniazid therapy in chronic ulcerative colitis; a preliminary report. ( SUSNOW, DA, 1954) |
" The current study aimed to investigate the potential impact of niacin on colitis-induced depressive-like behavior in rats." | 4.31 | Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms. ( Abd El-Haleim, EA; Khayyal, MT; Mohamed, SS; Wadie, W, 2023) |
"Hydroxycarboxylic acid receptor 2 (HCAR2), modulated by endogenous ketone body β-hydroxybutyrate and exogenous niacin, is a promising therapeutic target for inflammation-related diseases." | 4.31 | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation. ( Cheng, L; Fu, H; Fu, P; Hu, H; Li, Z; Liu, Y; Ma, L; Shao, Z; Shen, C; Tian, X; Wang, B; Wang, C; Wang, H; Wu, C; Yan, W; Yang, S; Yu, J; Zhao, C, 2023) |
"Uniformly good response to isoniazid therapy was observed in five cases of chronic ulcerative colitis during an initial period of 3 to 6 months of treatment." | 3.63 | Isoniazid therapy in chronic ulcerative colitis; a preliminary report. ( SUSNOW, DA, 1954) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (50.00) | 18.7374 |
1990's | 1 (8.33) | 18.2507 |
2000's | 1 (8.33) | 29.6817 |
2010's | 2 (16.67) | 24.3611 |
2020's | 2 (16.67) | 2.80 |
Authors | Studies |
---|---|
Wadie, W | 1 |
Mohamed, SS | 1 |
Abd El-Haleim, EA | 1 |
Khayyal, MT | 1 |
Zhao, C | 1 |
Wang, H | 1 |
Liu, Y | 1 |
Cheng, L | 1 |
Wang, B | 1 |
Tian, X | 1 |
Fu, H | 1 |
Wu, C | 1 |
Li, Z | 1 |
Shen, C | 1 |
Yu, J | 1 |
Yang, S | 1 |
Hu, H | 1 |
Fu, P | 1 |
Ma, L | 1 |
Wang, C | 1 |
Yan, W | 1 |
Shao, Z | 1 |
Singh, N | 1 |
Gurav, A | 1 |
Sivaprakasam, S | 1 |
Brady, E | 1 |
Padia, R | 1 |
Shi, H | 1 |
Thangaraju, M | 1 |
Prasad, PD | 1 |
Manicassamy, S | 1 |
Munn, DH | 1 |
Lee, JR | 1 |
Offermanns, S | 1 |
Ganapathy, V | 1 |
Graff, EC | 1 |
Fang, H | 1 |
Wanders, D | 1 |
Judd, RL | 1 |
SUSNOW, DA | 1 |
WEILLER, P | 1 |
SAMITZ, MH | 1 |
RAMZY, I | 1 |
Lu, JY | 1 |
Yu, CL | 1 |
Wu, MZ | 1 |
Clayton, PT | 1 |
Bridges, NA | 1 |
Atherton, DJ | 1 |
Milla, PJ | 1 |
Malone, M | 1 |
Bender, DA | 1 |
Segal, I | 1 |
Ou Tim, L | 1 |
Demetriou, A | 1 |
Paterson, A | 1 |
Hale, M | 1 |
Lerios, M | 1 |
1 review available for niacin and Colitis
Article | Year |
---|---|
Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2.
Topics: Animals; Atherosclerosis; Colitis; Diabetic Retinopathy; Humans; Inflammation; Mice; Neoplasms; Neur | 2016 |
11 other studies available for niacin and Colitis
Article | Year |
---|---|
Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms.
Topics: Animals; Benzilates; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Niacin; Rat | 2023 |
Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Topics: Allosteric Regulation; Animals; Colitis; GTP-Binding Protein alpha Subunits, Gi-Go; Inflammation; Ke | 2023 |
Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.
Topics: Animals; Butyrates; Carcinogenesis; Cell Differentiation; Cells, Cultured; Colitis; Colon; Colonic N | 2014 |
Isoniazid therapy in chronic ulcerative colitis; a preliminary report.
Topics: Colitis; Colitis, Ulcerative; Humans; Isoniazid; Niacin; Nicotinic Acids | 1954 |
[Use of isoniazid in therapy of painful colitis of the ileocecal region].
Topics: Colitis; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pain | 1955 |
[Some apparently unusual secondary effects of isonicotinic acid hydrazide on the digestive tract].
Topics: Colitis; Constipation; Gastrointestinal Tract; Humans; Isoniazid; Niacin; Nicotinic Acids; Peptic Ul | 1955 |
SKIN MANIFESTATIONS OF GASTROINTESTINAL DISEASES. I.
Topics: Celiac Disease; Colitis; Colitis, Ulcerative; Dermatology; Gastroenterology; Gastrointestinal Diseas | 1963 |
COLITIS GLANDULARIS CYSTICA; (CASE REPORT).
Topics: Colitis; Colonic Diseases; Cysts; Humans; Pathology; Pellagra; Schistosomiasis | 1964 |
Pellagra in an immunocompetent patient with cytomegalovirus colitis.
Topics: Colitis; Cytomegalovirus Infections; Humans; Immunocompetence; Male; Middle Aged; Pellagra | 2001 |
Pellagra with colitis due to a defect in tryptophan metabolism.
Topics: Child; Colitis; Female; Humans; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Niacinamide; | 1991 |
Rectal manifestations of pellagra.
Topics: Adult; Aged; Colitis; Colonic Diseases; Diarrhea; Female; Humans; Male; Middle Aged; Pellagra; Skin | 1986 |