niacin and Colitis
niacin has been researched along with Colitis in 12 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study aimed to investigate the potential impact of niacin on colitis-induced depressive-like behavior in rats." | 8.31 | Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms. ( Abd El-Haleim, EA; Khayyal, MT; Mohamed, SS; Wadie, W, 2023) |
| "Uniformly good response to isoniazid therapy was observed in five cases of chronic ulcerative colitis during an initial period of 3 to 6 months of treatment." | 7.63 | Isoniazid therapy in chronic ulcerative colitis; a preliminary report. ( SUSNOW, DA, 1954) |
| " The current study aimed to investigate the potential impact of niacin on colitis-induced depressive-like behavior in rats." | 4.31 | Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms. ( Abd El-Haleim, EA; Khayyal, MT; Mohamed, SS; Wadie, W, 2023) |
| "Hydroxycarboxylic acid receptor 2 (HCAR2), modulated by endogenous ketone body β-hydroxybutyrate and exogenous niacin, is a promising therapeutic target for inflammation-related diseases." | 4.31 | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation. ( Cheng, L; Fu, H; Fu, P; Hu, H; Li, Z; Liu, Y; Ma, L; Shao, Z; Shen, C; Tian, X; Wang, B; Wang, C; Wang, H; Wu, C; Yan, W; Yang, S; Yu, J; Zhao, C, 2023) |
| "Uniformly good response to isoniazid therapy was observed in five cases of chronic ulcerative colitis during an initial period of 3 to 6 months of treatment." | 3.63 | Isoniazid therapy in chronic ulcerative colitis; a preliminary report. ( SUSNOW, DA, 1954) |
Research
Studies (12)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Wadie, W | 1 |
| Mohamed, SS | 1 |
| Abd El-Haleim, EA | 1 |
| Khayyal, MT | 1 |
| Zhao, C | 1 |
| Wang, H | 1 |
| Liu, Y | 1 |
| Cheng, L | 1 |
| Wang, B | 1 |
| Tian, X | 1 |
| Fu, H | 1 |
| Wu, C | 1 |
| Li, Z | 1 |
| Shen, C | 1 |
| Yu, J | 1 |
| Yang, S | 1 |
| Hu, H | 1 |
| Fu, P | 1 |
| Ma, L | 1 |
| Wang, C | 1 |
| Yan, W | 1 |
| Shao, Z | 1 |
| Singh, N | 1 |
| Gurav, A | 1 |
| Sivaprakasam, S | 1 |
| Brady, E | 1 |
| Padia, R | 1 |
| Shi, H | 1 |
| Thangaraju, M | 1 |
| Prasad, PD | 1 |
| Manicassamy, S | 1 |
| Munn, DH | 1 |
| Lee, JR | 1 |
| Offermanns, S | 1 |
| Ganapathy, V | 1 |
| Graff, EC | 1 |
| Fang, H | 1 |
| Wanders, D | 1 |
| Judd, RL | 1 |
| SUSNOW, DA | 1 |
| WEILLER, P | 1 |
| SAMITZ, MH | 1 |
| RAMZY, I | 1 |
| Lu, JY | 1 |
| Yu, CL | 1 |
| Wu, MZ | 1 |
| Clayton, PT | 1 |
| Bridges, NA | 1 |
| Atherton, DJ | 1 |
| Milla, PJ | 1 |
| Malone, M | 1 |
| Bender, DA | 1 |
| Segal, I | 1 |
| Ou Tim, L | 1 |
| Demetriou, A | 1 |
| Paterson, A | 1 |
| Hale, M | 1 |
| Lerios, M | 1 |
Reviews
1 review available for niacin and Colitis
| Article | Year |
|---|---|
Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2.
Topics: Animals; Atherosclerosis; Colitis; Diabetic Retinopathy; Humans; Inflammation; Mice; Neoplasms; Neur | 2016 |
Other Studies
11 other studies available for niacin and Colitis
| Article | Year |
|---|---|
Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms.
Topics: Animals; Benzilates; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Niacin; Rat | 2023 |
Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Topics: Allosteric Regulation; Animals; Colitis; GTP-Binding Protein alpha Subunits, Gi-Go; Inflammation; Ke | 2023 |
Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.
Topics: Animals; Butyrates; Carcinogenesis; Cell Differentiation; Cells, Cultured; Colitis; Colon; Colonic N | 2014 |
Isoniazid therapy in chronic ulcerative colitis; a preliminary report.
Topics: Colitis; Colitis, Ulcerative; Humans; Isoniazid; Niacin; Nicotinic Acids | 1954 |
[Use of isoniazid in therapy of painful colitis of the ileocecal region].
Topics: Colitis; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pain | 1955 |
[Some apparently unusual secondary effects of isonicotinic acid hydrazide on the digestive tract].
Topics: Colitis; Constipation; Gastrointestinal Tract; Humans; Isoniazid; Niacin; Nicotinic Acids; Peptic Ul | 1955 |
SKIN MANIFESTATIONS OF GASTROINTESTINAL DISEASES. I.
Topics: Celiac Disease; Colitis; Colitis, Ulcerative; Dermatology; Gastroenterology; Gastrointestinal Diseas | 1963 |
COLITIS GLANDULARIS CYSTICA; (CASE REPORT).
Topics: Colitis; Colonic Diseases; Cysts; Humans; Pathology; Pellagra; Schistosomiasis | 1964 |
Pellagra in an immunocompetent patient with cytomegalovirus colitis.
Topics: Colitis; Cytomegalovirus Infections; Humans; Immunocompetence; Male; Middle Aged; Pellagra | 2001 |
Pellagra with colitis due to a defect in tryptophan metabolism.
Topics: Child; Colitis; Female; Humans; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Niacinamide; | 1991 |
Rectal manifestations of pellagra.
Topics: Adult; Aged; Colitis; Colonic Diseases; Diarrhea; Female; Humans; Male; Middle Aged; Pellagra; Skin | 1986 |