niacin has been researched along with Cockayne Syndrome in 2 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Cockayne Syndrome: A syndrome characterized by multiple system abnormalities including DWARFISM; PHOTOSENSITIVITY DISORDERS; PREMATURE AGING; and HEARING LOSS. It is caused by mutations of a number of autosomal recessive genes encoding proteins that involve transcriptional-coupled DNA REPAIR processes. Cockayne syndrome is classified by the severity and age of onset. Type I (classical; CSA) is early childhood onset in the second year of life; type II (congenital; CSB) is early onset at birth with severe symptoms; type III (xeroderma pigmentosum; XP) is late childhood onset with mild symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An extremely rare pellagra-like condition has been described, which was partially responsive to niacin and associated with a multisystem involvement." | 7.81 | Pellagra-like condition is xeroderma pigmentosum/Cockayne syndrome complex and niacin confers clinical benefit. ( Alkuraya, FS; Ansari, S; Hamad, MH; Hassan, HH; Hijazi, H; Ibrahim, N; Karrar, ZA; Mohamed, KA; Mukhtar, MM; Salih, MA; Salih, SB, 2015) |
| "An extremely rare pellagra-like condition has been described, which was partially responsive to niacin and associated with a multisystem involvement." | 3.81 | Pellagra-like condition is xeroderma pigmentosum/Cockayne syndrome complex and niacin confers clinical benefit. ( Alkuraya, FS; Ansari, S; Hamad, MH; Hassan, HH; Hijazi, H; Ibrahim, N; Karrar, ZA; Mohamed, KA; Mukhtar, MM; Salih, MA; Salih, SB, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hijazi, H | 1 |
| Salih, MA | 1 |
| Hamad, MH | 1 |
| Hassan, HH | 1 |
| Salih, SB | 1 |
| Mohamed, KA | 1 |
| Mukhtar, MM | 1 |
| Karrar, ZA | 1 |
| Ansari, S | 1 |
| Ibrahim, N | 1 |
| Alkuraya, FS | 1 |
| Bligard, CA | 1 |
| Storer, JS | 1 |
2 other studies available for niacin and Cockayne Syndrome
| Article | Year |
|---|---|
Pellagra-like condition is xeroderma pigmentosum/Cockayne syndrome complex and niacin confers clinical benefit.
Topics: Base Sequence; Child, Preschool; Cockayne Syndrome; Comet Assay; DNA Damage; DNA-Binding Proteins; E | 2015 |
Photosensitivity in infants and children.
Topics: Bloom Syndrome; Child; Child, Preschool; Cockayne Syndrome; Female; Hartnup Disease; Humans; Hydroa | 1986 |