niacin has been researched along with Chronic Disease in 34 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the safety, tolerance, and efficacy of extended-release niacin monotherapy on dyslipidemia in persons with chronic tetraplegia." | 9.15 | Safety, tolerance, and efficacy of extended-release niacin monotherapy for treating dyslipidemia risks in persons with chronic tetraplegia: a randomized multicenter controlled trial. ( Bauman, WA; Dyson-Hudson, TA; Lewis, JE; Mendez, AJ; Nash, MS; Spungen, AM; Szlachcic, Y; Yee, F, 2011) |
| "To test the safety, tolerance, and efficacy of extended-release niacin monotherapy on dyslipidemia in persons with chronic tetraplegia." | 5.15 | Safety, tolerance, and efficacy of extended-release niacin monotherapy for treating dyslipidemia risks in persons with chronic tetraplegia: a randomized multicenter controlled trial. ( Bauman, WA; Dyson-Hudson, TA; Lewis, JE; Mendez, AJ; Nash, MS; Spungen, AM; Szlachcic, Y; Yee, F, 2011) |
| "We performed a post hoc data analysis of serum phosphorus concentrations that had been determined serially (at baseline and weeks 4, 8, 12, 18, and 24) among 1547 patients who had dyslipidemia and were randomly assigned in a 3:2:1 ratio to treatment with extended release niacin (ERN; 1 g/d for 4 weeks and dose advanced to 2 g/d for 20 weeks) combined with the selective prostaglandin D2 receptor subtype 1 inhibitor laropiprant (L; n = 761), ERN alone (n = 518), or placebo (n = 268)." | 5.14 | Hypophosphatemic effect of niacin in patients without renal failure: a randomized trial. ( Bostom, AG; Hanlon, WA; Kuznetsova, O; Maccubbin, D; Tipping, D, 2010) |
| "These results demonstrate that alcoholic fatty liver was not exaggerated by dietary NA deficiency, but was ameliorated by dietary NA supplementation." | 1.40 | Dietary nicotinic acid supplementation ameliorates chronic alcohol-induced fatty liver in rats. ( Jia, W; Li, Q; Sun, X; Tan, X; Xie, G; Zhang, W; Zhong, W; Zhou, Z, 2014) |
| "Niacin was started and followed by dramatic improvement." | 1.40 | Severe persistent unremitting dermatitis, chronic diarrhea and hypoalbuminemia in a child; Hartnup disease in setting of celiac disease. ( Awar, M; Ciecierega, T; Dweikat, I; Libdeh, BA; Shahrour, M; Sultan, M, 2014) |
| " Dose recommendations for these patients are not available because pharmacokinetic data are missing." | 1.37 | Pharmacokinetics and dose recommendations of Niaspan® in chronic kidney disease and dialysis patients. ( Bode-Böger, SM; Luley, C; Martens-Lobenhoffer, J; Reiche, I; Tröger, U; Westphal, S, 2011) |
| "It is of no value in differentiating Gilbert's syndrome from liver disease." | 1.28 | The nicotinic acid provocation test and unconjugated hyperbilirubinaemia. ( Callender, ME; Dickey, W; McAleer, JJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (47.06) | 18.7374 |
| 1990's | 2 (5.88) | 18.2507 |
| 2000's | 5 (14.71) | 29.6817 |
| 2010's | 10 (29.41) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, H | 1 |
| Wang, C | 1 |
| Pan, Y | 1 |
| Guo, Y | 1 |
| Yao, N | 1 |
| Wang, H | 1 |
| Jin, L | 1 |
| Li, B | 1 |
| Li, Q | 1 |
| Xie, G | 1 |
| Zhang, W | 1 |
| Zhong, W | 1 |
| Sun, X | 2 |
| Tan, X | 1 |
| Jia, W | 1 |
| Zhou, Z | 1 |
| Ciecierega, T | 1 |
| Dweikat, I | 1 |
| Awar, M | 1 |
| Shahrour, M | 1 |
| Libdeh, BA | 1 |
| Sultan, M | 1 |
| CAYER, D | 1 |
| CODY, S | 1 |
| Bostom, AG | 2 |
| Maccubbin, D | 1 |
| Tipping, D | 1 |
| Kuznetsova, O | 1 |
| Hanlon, WA | 1 |
| Moorthi, RN | 1 |
| Moe, SM | 1 |
| Drüeke, T | 1 |
| Uhlig, K | 1 |
| Reiche, I | 1 |
| Westphal, S | 1 |
| Martens-Lobenhoffer, J | 1 |
| Tröger, U | 1 |
| Luley, C | 1 |
| Bode-Böger, SM | 1 |
| Nash, MS | 1 |
| Lewis, JE | 1 |
| Dyson-Hudson, TA | 1 |
| Szlachcic, Y | 1 |
| Yee, F | 1 |
| Mendez, AJ | 1 |
| Spungen, AM | 1 |
| Bauman, WA | 1 |
| Knab, AM | 1 |
| Shanely, RA | 1 |
| Henson, DA | 1 |
| Jin, F | 1 |
| Heinz, SA | 1 |
| Austin, MD | 1 |
| Nieman, DC | 1 |
| LAI, G | 1 |
| LOMBARDI, AV | 1 |
| GOLDBERG, LC | 1 |
| SIMON, CR | 1 |
| MARTELLI, A | 1 |
| PEROSA, L | 1 |
| COLONNA, L | 1 |
| BINI, L | 1 |
| DESANTIS, M | 1 |
| MORSIANI, M | 1 |
| CALIFANO, A | 1 |
| ESPOSITO, S | 1 |
| PETRONIO, L | 1 |
| GILUNOVA, NI | 1 |
| DE FRANCESCO, F | 1 |
| Kwan, BC | 1 |
| Kronenberg, F | 1 |
| Beddhu, S | 1 |
| Cheung, AK | 1 |
| Restrepo Valencia, CA | 1 |
| Cruz, J | 1 |
| Okhrimovich, LM | 1 |
| Cherniavskaia, GF | 1 |
| Zhura, II | 1 |
| Kushnir, LP | 1 |
| Essama-Tjani, JC | 1 |
| Guilland, JC | 1 |
| Fuchs, F | 1 |
| Lombard, M | 1 |
| Richard, D | 1 |
| Hannan, F | 1 |
| Davoren, P | 1 |
| Dickey, W | 1 |
| McAleer, JJ | 1 |
| Callender, ME | 1 |
| Gentile, S | 1 |
| Del Vecchio Blanco, C | 1 |
| Persico, M | 1 |
| Marmo, R | 1 |
| Coltorti, M | 1 |
| Schlomer, T | 1 |
| Di Lucca, J | 1 |
| Bart, PA | 1 |
| Zhang, LW | 1 |
| Zhang, Y | 1 |
| Chen, T | 1 |
| TERRIS, M | 1 |
| Wilcox, LS | 1 |
| Mancinella, G | 1 |
| Liuti, G | 1 |
| Vartolo, C | 1 |
| Furno, A | 1 |
| Benítez León, MD | 1 |
| Tercedor, J | 1 |
| Ibáñez Pérez de la Blanca, A | 1 |
| Martí García, J | 1 |
| Heyl, T | 1 |
| Seftel, HC | 1 |
3 reviews available for niacin and Chronic Disease
| Article | Year |
|---|---|
Lipoprotein metabolism and lipid management in chronic kidney disease.
Topics: Antioxidants; Cardiovascular Diseases; Chronic Disease; Dyslipidemias; Humans; Hydroxymethylglutaryl | 2007 |
[Cutaneous manifestations of nutritional deficiencies].
Topics: Acrodermatitis; Chronic Disease; Humans; Malnutrition; Pellagra; Scurvy; Skin Diseases | 2019 |
[Dermatitis and neurological changes].
Topics: Adult; Chronic Disease; Dermatitis; Diagnosis, Differential; Female; Humans; Nervous System Diseases | 1995 |
3 trials available for niacin and Chronic Disease
| Article | Year |
|---|---|
Hypophosphatemic effect of niacin in patients without renal failure: a randomized trial.
Topics: Aged; Biomarkers; Calcium; Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Drug T | 2010 |
Safety, tolerance, and efficacy of extended-release niacin monotherapy for treating dyslipidemia risks in persons with chronic tetraplegia: a randomized multicenter controlled trial.
Topics: Adolescent; Adult; Aged; Cholesterol; Chronic Disease; Delayed-Action Preparations; Double-Blind Met | 2011 |
Influence of quercetin supplementation on disease risk factors in community-dwelling adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antioxidants; Ascorbic Acid; Blood | 2011 |
28 other studies available for niacin and Chronic Disease
| Article | Year |
|---|---|
Niacin, lutein and zeaxanthin and physical activity have an impact on Charlson comorbidity index using zero-inflated negative binomial regression model: National Health and Nutrition Examination Survey 2013-2014.
Topics: Adult; Aged; Chronic Disease; Comorbidity; Diet; Energy Intake; Exercise; Female; Humans; Lutein; Ma | 2019 |
Dietary nicotinic acid supplementation ameliorates chronic alcohol-induced fatty liver in rats.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Oxidase; Adiponectin; Animals; Chronic Disease; Cytochrome P-450 CYP | 2014 |
Severe persistent unremitting dermatitis, chronic diarrhea and hypoalbuminemia in a child; Hartnup disease in setting of celiac disease.
Topics: Celiac Disease; Child, Preschool; Chronic Disease; Dermatitis, Exfoliative; Diarrhea; Erythema; Fema | 2014 |
Urinary excretion of niacin and riboflavin in patients with acute infections and various chronic diseases.
Topics: Acute Disease; Chronic Disease; Humans; Infections; Niacin; Nicotinic Acids; Riboflavin; Urine | 1948 |
Binder blinders-niacin of omission?
Topics: Animals; Cardiovascular Diseases; Chronic Disease; Clinical Trials as Topic; Humans; Hyperphosphatem | 2010 |
All research does not a guideline make!
Topics: Biomedical Research; Bone Diseases; Chronic Disease; Humans; Kidney Diseases; Niacin; Phosphorus Met | 2010 |
Pharmacokinetics and dose recommendations of Niaspan® in chronic kidney disease and dialysis patients.
Topics: Aged; Chronic Disease; Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; | 2011 |
[Case of polyserositis treated with isonicotinic acid hydrazide].
Topics: Chronic Disease; Inflammation; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Serositis | 1952 |
[Effect of nicotinic acid and oxygen therapy in cor pulmonale].
Topics: Chronic Disease; Humans; Hypertension, Pulmonary; Niacin; Nicotinic Acids; Oxygen; Oxygen Inhalation | 1953 |
Isoniazid therapy of chronic dermatoses.
Topics: Chronic Disease; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases | 1953 |
[Special use of nicotine-k-strophanthin; chronic pulmonary heart disease].
Topics: Chronic Disease; Humans; Niacin; Nicotine; Nicotinic Acids; Pulmonary Heart Disease; Strophanthins | 1953 |
[Blood circulation after nicotinic acid administration in chronic cor pulmonale].
Topics: Chronic Disease; Humans; Hypertension, Pulmonary; Niacin; Nicotinic Acids; Pulmonary Heart Disease | 1956 |
[6-Aminonicotinamide: hematological investigations during chronic poisoning in rats].
Topics: 6-Aminonicotinamide; Animals; Antineoplastic Agents; Blood; Chronic Disease; Niacin; Nicotinic Acids | 1958 |
[Certain histological aspects in chronic poisoning by 6-aminonicotinamide; experimental research on the rabbit].
Topics: 6-Aminonicotinamide; Animals; Antineoplastic Agents; Chronic Disease; Niacin; Nicotinic Acids; Nicot | 1959 |
[PYRIDOXINE AND NICOTINIC ACID METABOLISM IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS].
Topics: Chronic Disease; Glomerulonephritis; Humans; Niacin; Nicotinic Acids; Pyridoxine; Vitamin B 6 Defici | 1965 |
[Treatment of chronic arthritic diseases; clinical note].
Topics: Arthritis; Chronic Disease; Humans; Niacin; Nicotinic Acids; Vitamin D; Vitamins | 1951 |
[Safety and effectiveness of nicotinic acid in the management of patients with chronic renal disease and hyperlipidemia associated to hyperphosphatemia].
Topics: Chronic Disease; Female; Humans; Hyperlipidemias; Hyperphosphatemia; Hypolipidemic Agents; Kidney Di | 2008 |
[Gastric secretory status in chronic cholecystitis during the treatment process].
Topics: Adolescent; Adult; Bile; Cholelithiasis; Chronic Disease; Female; Gastric Mucosa; Humans; Liver; Mal | 1982 |
Changes in thiamin, riboflavin, niacin, beta-carotene, vitamins, C, A, D and E status of French Elderly Subjects during the first year of institutionalization.
Topics: Aged; Aged, 80 and over; Aging; Alcohol Drinking; Ascorbic Acid; beta Carotene; Chronic Disease; Fra | 2000 |
Use of nicotinic acid in the management of recurrent hypoglycemic episodes in diabetes.
Topics: Blood Glucose; Chronic Disease; Diabetes Mellitus, Type 1; Female; Humans; Hypoglycemia; Insulin; Mi | 2001 |
The nicotinic acid provocation test and unconjugated hyperbilirubinaemia.
Topics: Bilirubin; Chronic Disease; Gilbert Disease; Humans; Hyperbilirubinemia; Injections, Intravenous; Li | 1991 |
Familial clustering of heterogeneous chronic unconjugated hyperbilirubinemia.
Topics: Adult; Child; Chronic Disease; Female; Half-Life; Humans; Hyperbilirubinemia, Hereditary; Male; Midd | 1986 |
sQuiz your knowledge! A case of dermatitis, psychosis, and diarrhoea.
Topics: Alcoholism; Anxiety; Chronic Disease; Delusional Parasitosis; Depression; Dermatitis; Diarrhea; Eryt | 2021 |
EPIDEMIOLOGIC APPROACH TO CHRONIC DISEASES.
Topics: Chronic Disease; Coronary Disease; Dental Caries; Epidemiology; History; Humans; Lung Neoplasms; Neo | 1964 |
Old black water.
Topics: Chronic Disease; Disaster Planning; Disasters; Humans; Pellagra; Relief Work; Socioeconomic Factors; | 2005 |
[An infrequent complication of chronic alcoholic hepatopathy: pellagra].
Topics: Adult; Chronic Disease; Female; Humans; Liver Diseases, Alcoholic; Niacinamide; Pantothenic Acid; Pe | 1980 |
Chronic protein malnutrition.
Topics: Chronic Disease; Humans; Kwashiorkor; Pellagra; Protein Deficiency; Protein-Energy Malnutrition | 1975 |
Cardiomyopathies in Johannesburg Bantu. II. Aetiology of idiopathic cardiomyopathy.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Alcoholism; Animals; Beriberi; Black or African American | 1972 |