Page last updated: 2024-10-19

niacin and Cell Transformation, Neoplastic

niacin has been researched along with Cell Transformation, Neoplastic in 5 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"Niacin deficiency causes dramatic genomic instability in bone marrow cells in an in vivo rat model."1.38Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis. ( Kirkland, JB, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zhao, C1
Zhang, H1
Zhou, J1
Liu, Q1
Lu, Q1
Zhang, Y1
Yu, X1
Wang, S1
Liu, R1
Pu, Y1
Yin, L1
Elangovan, S1
Pathania, R1
Ramachandran, S1
Ananth, S1
Padia, RN1
Lan, L1
Singh, N1
Martin, PM1
Hawthorn, L1
Prasad, PD1
Ganapathy, V1
Thangaraju, M1
Kirkland, JB1
Wang, GQ2
Dawsey, SM2
Li, JY2
Taylor, PR2
Li, B2
Blot, WJ2
Weinstein, WM2
Liu, FS2
Lewin, KJ2
Wang, H1
Wiggett, S1

Trials

2 trials available for niacin and Cell Transformation, Neoplastic

ArticleYear
Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the General Population Trial in Linxian, China.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1994, Volume: 3, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Ascorbic Acid; beta Carotene; Carotenoids; Cell Transformation, Neoplas

1994
Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the Dysplasia Trial in Linxian, China.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1994, Volume: 3, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Ascorbic Acid; beta Carotene; Carotenoids; Cell Transformation, Neoplas

1994

Other Studies

3 other studies available for niacin and Cell Transformation, Neoplastic

ArticleYear
Metabolomic transition trajectory and potential mechanisms of N-nitrosomethylbenzylamine induced esophageal squamous cell carcinoma in rats.
    Ecotoxicology and environmental safety, 2022, Oct-01, Volume: 244

    Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Dimethylnitrosami

2022
The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.
    Cancer research, 2014, Feb-15, Volume: 74, Issue:4

    Topics: Animals; Breast Neoplasms; Butyrates; Cell Survival; Cell Transformation, Neoplastic; Cells, Culture

2014
Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis.
    Sub-cellular biochemistry, 2012, Volume: 56

    Topics: Animals; Avitaminosis; Bone Marrow Cells; Cell Transformation, Neoplastic; Disease Models, Animal; D

2012