niacin has been researched along with Cell Transformation, Neoplastic in 5 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niacin deficiency causes dramatic genomic instability in bone marrow cells in an in vivo rat model." | 1.38 | Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis. ( Kirkland, JB, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, C | 1 |
| Zhang, H | 1 |
| Zhou, J | 1 |
| Liu, Q | 1 |
| Lu, Q | 1 |
| Zhang, Y | 1 |
| Yu, X | 1 |
| Wang, S | 1 |
| Liu, R | 1 |
| Pu, Y | 1 |
| Yin, L | 1 |
| Elangovan, S | 1 |
| Pathania, R | 1 |
| Ramachandran, S | 1 |
| Ananth, S | 1 |
| Padia, RN | 1 |
| Lan, L | 1 |
| Singh, N | 1 |
| Martin, PM | 1 |
| Hawthorn, L | 1 |
| Prasad, PD | 1 |
| Ganapathy, V | 1 |
| Thangaraju, M | 1 |
| Kirkland, JB | 1 |
| Wang, GQ | 2 |
| Dawsey, SM | 2 |
| Li, JY | 2 |
| Taylor, PR | 2 |
| Li, B | 2 |
| Blot, WJ | 2 |
| Weinstein, WM | 2 |
| Liu, FS | 2 |
| Lewin, KJ | 2 |
| Wang, H | 1 |
| Wiggett, S | 1 |
2 trials available for niacin and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the General Population Trial in Linxian, China.
Topics: Adenocarcinoma; Adult; Aged; Ascorbic Acid; beta Carotene; Carotenoids; Cell Transformation, Neoplas | 1994 |
Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the Dysplasia Trial in Linxian, China.
Topics: Adenocarcinoma; Adult; Aged; Ascorbic Acid; beta Carotene; Carotenoids; Cell Transformation, Neoplas | 1994 |
3 other studies available for niacin and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Metabolomic transition trajectory and potential mechanisms of N-nitrosomethylbenzylamine induced esophageal squamous cell carcinoma in rats.
Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Dimethylnitrosami | 2022 |
The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.
Topics: Animals; Breast Neoplasms; Butyrates; Cell Survival; Cell Transformation, Neoplastic; Cells, Culture | 2014 |
Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis.
Topics: Animals; Avitaminosis; Bone Marrow Cells; Cell Transformation, Neoplastic; Disease Models, Animal; D | 2012 |