niacin has been researched along with Carcinoma, Hepatocellular in 12 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU) as chemotherapy in cases of hepatocellular carcinoma (HCC), was found to initiate hepatotoxic injuries, ascites, leucopenia, thrombocytopenia and myelosupression that limit its use." | 7.72 | A combination therapy with copper nicotinate complex reduces the adverse effects of 5-fluorouracil on patients with hepatocellular carcinoma. ( El-Saadani, MA, 2004) |
| "5-Fluorouracil (5-FU) as chemotherapy in cases of hepatocellular carcinoma (HCC), was found to initiate hepatotoxic injuries, ascites, leucopenia, thrombocytopenia and myelosupression that limit its use." | 3.72 | A combination therapy with copper nicotinate complex reduces the adverse effects of 5-fluorouracil on patients with hepatocellular carcinoma. ( El-Saadani, MA, 2004) |
| "The primary hepatoma group had 4 with ETK coenzyme effects above 30%, and 3 of the 4 had low level urinary thiamine excretions." | 1.26 | Effects of vitamins B1, B2, B6 and C on erythrocyte enzymes in South African Bantu. ( Hankes, L; Oosthuysen, AW; Yeh, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanafy, NAN | 1 |
| Sheashaa, RF | 1 |
| Moussa, EA | 1 |
| Mahfouz, ME | 1 |
| Feng, PP | 1 |
| Qi, YK | 1 |
| Li, N | 1 |
| Fei, HR | 1 |
| Yan, D | 1 |
| Xu, J | 1 |
| Tan, X | 1 |
| REVEL, M | 1 |
| MANDEL, L | 1 |
| WINTZERITH, M | 1 |
| KLEIN, N | 1 |
| MANDEL, P | 1 |
| CLARK, JB | 1 |
| GREENBAUM, AL | 1 |
| MCLEAN, P | 1 |
| REID, E | 1 |
| NOGUCHI, S | 1 |
| NAKATA, Y | 1 |
| JINNAI, D | 1 |
| SAKAMOTO, Y | 1 |
| Hasmann, M | 1 |
| Schemainda, I | 1 |
| El-Saadani, MA | 1 |
| Yeh, YK | 1 |
| Hankes, LV | 2 |
| Wessels, LM | 1 |
| Henning, SM | 1 |
| Swendseid, ME | 1 |
| Ivandic, BT | 1 |
| Liao, F | 1 |
| Schmaeler, M | 1 |
| Jansen, CR | 1 |
| Brown, RR | 1 |
| Yeh, J | 1 |
| Hankes, L | 1 |
| Oosthuysen, AW | 1 |
12 other studies available for niacin and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Potential of curcumin and niacin-loaded targeted chitosan coated liposomes to activate autophagy in hepatocellular carcinoma cells: An in vitro evaluation in HePG2 cell line.
Topics: Autophagy; Carcinoma, Hepatocellular; Chitosan; Curcumin; Drug Carriers; Hep G2 Cells; Humans; Lipos | 2023 |
Scutebarbatine A induces cytotoxicity in hepatocellular carcinoma via activation of the MAPK and ER stress signaling pathways.
Topics: Carcinoma, Hepatocellular; Cytotoxins; Endoplasmic Reticulum Stress; Extracellular Signal-Regulated | 2021 |
Inhibitory investigation of niacin derivatives on metalloenzyme indoleamine 2,3-dioxygenase 1 for its immunomodulatory function.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Design; Enzy | 2021 |
[Regulation of the biosynthesis of ribonucleic acids. Action of nicotinamide].
Topics: Animals; Carcinoma, Hepatocellular; Kidney; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; N | 1961 |
CONCENTRATIONS AND RATES OF SYNTHESIS OF NICOTINAMIDE-ADENINE-DINUCLEODIDE PHOSPHATE IN PRECANCEROUS LIVERS AND HEPATOMAS INDUCED BY AZO-DYE FEEDING.
Topics: Adenine; Carcinogens; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; NADP; Neoplasms; Neoplasms, | 1964 |
[STUDIES ON NICOTINAMIDE METHYLPHERASE ACTIVITY IN THE LIVER OF TUMOR-BEARING RAT].
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Carcinoma, Hepatocellular; Cortisone; Endotoxins; Fluoro | 1964 |
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Topics: Acrylamides; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Ce | 2003 |
A combination therapy with copper nicotinate complex reduces the adverse effects of 5-fluorouracil on patients with hepatocellular carcinoma.
Topics: Alkaline Phosphatase; Antimetabolites, Antineoplastic; Bilirubin; Carcinoma, Hepatocellular; Cerulop | 2004 |
Pyridine nucleotide metabolism in the erythrocyte of South African blacks with primary hepatoma.
Topics: Black People; Carcinoma, Hepatocellular; Erythrocytes; Humans; Liver Neoplasms; Models, Biological; | 1982 |
Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets.
Topics: Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Heme O | 1997 |
Vitamin effects on tryptophan-niacin metabolism in primary hepatoma patients.
Topics: 3-Hydroxyanthranilic Acid; Biotransformation; Black People; Carbon Radioisotopes; Carcinoma, Hepatoc | 1999 |
Effects of vitamins B1, B2, B6 and C on erythrocyte enzymes in South African Bantu.
Topics: Alanine Transaminase; Ascorbic Acid; Black People; Carcinoma, Hepatocellular; Erythrocytes; Glutathi | 1982 |