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niacin and Breast Neoplasms

niacin has been researched along with Breast Neoplasms in 15 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"In the present study, eighty-four breast cancer patients were randomized to receive a daily supplement of 100 mg co-enzyme Q10, 10 mg riboflavin and 50 mg niacin (CoRN), one dosage per d along with 10 mg tamoxifen twice per d."9.13Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy. ( Premkumar, VG; Sachdanandam, P; Shanthi, P; Yuvaraj, S, 2008)
"The prognostic significance of supplementing co-enzyme Q(10) (CoQ(10)), riboflavin and niacin (CoRN) along with tamoxifen to breast cancer patients was evaluated by measuring the serum cytokine levels of interleukin (IL)-1beta, IL-6, IL-8, tumour necrosis factor alpha (TNF-alpha) and vascular endothelial growth factor."9.12Serum cytokine levels of interleukin-1beta, -6, -8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin. ( Gangadaran, SG; Premkumar, VG; Sachdanandam, P; Vijayasarathy, K; Yuvaraj, S, 2007)
" Tamoxifen (TAM) is a non-steroidal anti-estrogen drug most widely used as an adjuvant hormonal therapy in breast cancer."7.74Augmented antioxidant status in Tamoxifen treated postmenopausal women with breast cancer on co-administration with Coenzyme Q10, Niacin and Riboflavin. ( Gangadaran, SG; Premkumar, VG; Sachdanandam, P; Vijayasarathy, K; Yuvaraj, S, 2008)
" In the present study, 84 breast cancer patients were randomized to receive a daily supplement of 100 mg coenzyme Q10 (CoQ10), 10 mg riboflavin and 50 mg niacin (CoRN) one dosage per day along with 10 mg tamoxifen (TAM) twice a day."6.73Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy. ( Gangadaran, SG; Premkumar, VG; Sachdanandam, P; Vijayasarathy, K; Yuvaraj, S, 2007)
"In the present study, eighty-four breast cancer patients were randomized to receive a daily supplement of 100 mg co-enzyme Q10, 10 mg riboflavin and 50 mg niacin (CoRN), one dosage per d along with 10 mg tamoxifen twice per d."5.13Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy. ( Premkumar, VG; Sachdanandam, P; Shanthi, P; Yuvaraj, S, 2008)
"The prognostic significance of supplementing co-enzyme Q(10) (CoQ(10)), riboflavin and niacin (CoRN) along with tamoxifen to breast cancer patients was evaluated by measuring the serum cytokine levels of interleukin (IL)-1beta, IL-6, IL-8, tumour necrosis factor alpha (TNF-alpha) and vascular endothelial growth factor."5.12Serum cytokine levels of interleukin-1beta, -6, -8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin. ( Gangadaran, SG; Premkumar, VG; Sachdanandam, P; Vijayasarathy, K; Yuvaraj, S, 2007)
" Tamoxifen (TAM) is a non-steroidal anti-estrogen drug most widely used as an adjuvant hormonal therapy in breast cancer."3.74Augmented antioxidant status in Tamoxifen treated postmenopausal women with breast cancer on co-administration with Coenzyme Q10, Niacin and Riboflavin. ( Gangadaran, SG; Premkumar, VG; Sachdanandam, P; Vijayasarathy, K; Yuvaraj, S, 2008)
" Tamoxifen (TAM), a nonsteroidal anti-estrogen drug most used in the chemotherapy and chemoprevention of breast cancer."3.73Augmented efficacy of tamoxifen in rat breast tumorigenesis when gavaged along with riboflavin, niacin, and CoQ10: effects on lipid peroxidation and antioxidants in mitochondria. ( Perumal, SS; Sachdanandam, P; Shanthi, P, 2005)
" In the present study, 84 breast cancer patients were randomized to receive a daily supplement of 100 mg coenzyme Q10 (CoQ10), 10 mg riboflavin and 50 mg niacin (CoRN) one dosage per day along with 10 mg tamoxifen (TAM) twice a day."2.73Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy. ( Gangadaran, SG; Premkumar, VG; Sachdanandam, P; Vijayasarathy, K; Yuvaraj, S, 2007)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's2 (13.33)18.2507
2000's7 (46.67)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdel-Mohsen, MA1
Abdel Malak, CA1
El-Shafey, ES1
Tabrizi, L1
Abyar, F1
Elangovan, S1
Pathania, R1
Ramachandran, S1
Ananth, S1
Padia, RN1
Lan, L1
Singh, N1
Martin, PM1
Hawthorn, L1
Prasad, PD1
Ganapathy, V1
Thangaraju, M1
Santolla, MF1
De Francesco, EM1
Lappano, R1
Rosano, C1
Abonante, S1
Maggiolini, M1
Wallach, I1
Jaitly, N1
Lilien, R1
ROSS, V1
Perumal, SS1
Shanthi, P3
Sachdanandam, P7
Premkumar, VG6
Yuvaraj, S6
Vijayasarathy, K5
Gangadaran, SG5
Jacobson, EL1
Shieh, WM1
Huang, AC1
Baghurst, PA1
Carman, JA1
Syrette, JA1
Baghurst, KI1
Crocker, JM1

Trials

3 trials available for niacin and Breast Neoplasms

ArticleYear
Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:2

    Topics: Aged; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoembryonic Antigen; Coenzymes; Dietar

2007
Serum cytokine levels of interleukin-1beta, -6, -8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Breast Neoplasms; Coenzymes; Cytokines; Drug Therapy,

2007
Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy.
    The British journal of nutrition, 2008, Volume: 100, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Breast Neoplasms; Dietary Supplements; DNA Methylation

2008

Other Studies

12 other studies available for niacin and Breast Neoplasms

ArticleYear
Influence of copper (I) nicotinate complex and autophagy modulation on doxorubicin-induced cytotoxicity in HCC1806 breast cancer cells.
    Advances in medical sciences, 2019, Volume: 64, Issue:1

    Topics: Apoptosis; Autophagy; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Copper; Doxorub

2019
De Novo Design of Cu(II) Complex Containing CNC-Pincer-Vitamin B3 and B7 Conjugates for Breast Cancer Application.
    Molecular pharmaceutics, 2019, 09-03, Volume: 16, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Biotin; Breast Neoplasms; Copper; DNA; DNA Cleavage; Drug Stabilit

2019
The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.
    Cancer research, 2014, Feb-15, Volume: 74, Issue:4

    Topics: Animals; Breast Neoplasms; Butyrates; Cell Survival; Cell Transformation, Neoplastic; Cells, Culture

2014
Niacin activates the G protein estrogen receptor (GPER)-mediated signalling.
    Cellular signalling, 2014, Volume: 26, Issue:7

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; ErbB Receptors; Extracellular

2014
A structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathways.
    PloS one, 2010, Aug-23, Volume: 5, Issue:8

    Topics: Breast Neoplasms; Computational Biology; Databases, Factual; Diabetes Mellitus, Type 2; Drug-Related

2010
Nicotinamide in adenocarcinoma 755 and in the milk of mice carrying the agent of spontaneous mammary tumor.
    Experientia, 1957, Dec-15, Volume: 13, Issue:12

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mice; Milk; Neoplasms,

1957
Augmented efficacy of tamoxifen in rat breast tumorigenesis when gavaged along with riboflavin, niacin, and CoQ10: effects on lipid peroxidation and antioxidants in mitochondria.
    Chemico-biological interactions, 2005, Feb-28, Volume: 152, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antioxidants; Body Weight; Breast N

2005
Ameliorating effect of coenzyme Q10, riboflavin and niacin in tamoxifen-treated postmenopausal breast cancer patients with special reference to lipids and lipoproteins.
    Clinical biochemistry, 2007, Volume: 40, Issue:9-10

    Topics: Adult; Aged; Breast Neoplasms; Cholesterol, LDL; Cholesterol, VLDL; Coenzymes; Drug Therapy, Combina

2007
Augmented antioxidant status in Tamoxifen treated postmenopausal women with breast cancer on co-administration with Coenzyme Q10, Niacin and Riboflavin.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antioxidants; Breast Neoplasms; Enzymes; Female; Human

2008
Effect of Coenzyme Q(10), Riboflavin and Niacin on Tamoxifen treated postmenopausal breast cancer women with special reference to blood chemistry profiles.
    Breast cancer research and treatment, 2009, Volume: 114, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Blood Chemical Analysis; Breast Neoplasms; Dietary Sup

2009
Mapping the role of NAD metabolism in prevention and treatment of carcinogenesis.
    Molecular and cellular biochemistry, 1999, Volume: 193, Issue:1-2

    Topics: Animals; Breast Neoplasms; Humans; Lung Neoplasms; NAD; Neoplasms; Niacin; Rats; Skin; Skin Neoplasm

1999
Diet, prolactin, and breast cancer.
    The American journal of clinical nutrition, 1992, Volume: 56, Issue:5

    Topics: Adult; Aged; Ascorbic Acid; Breast Neoplasms; Diet; Dietary Fats; Estrogens; Fatty Acids; Female; Hu

1992