niacin has been researched along with Benign Neoplasms in 69 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Research into the functions of nicotinamide adenine dinucleotide (NAD) has intensified in recent years due to the insight that abnormally low levels of NAD are involved in many human pathologies including metabolic disorders, neurodegeneration, reproductive dysfunction, cancer, and aging." | 9.41 | Beyond Pellagra-Research Models and Strategies Addressing the Enduring Clinical Relevance of NAD Deficiency in Aging and Disease. ( Feuz, MB; Meyer, RG; Meyer-Ficca, ML, 2023) |
| "In these symptoms, AIDS resembles classical pellagra due to dietary deficiency of Trp and niacin." | 6.38 | Implications of interferon-induced tryptophan catabolism in cancer, auto-immune diseases and AIDS. ( Borden, EC; Brown, RR; Datta, SP; Malone, DG; Ozaki, Y; Sondel, PM, 1991) |
| "Research into the functions of nicotinamide adenine dinucleotide (NAD) has intensified in recent years due to the insight that abnormally low levels of NAD are involved in many human pathologies including metabolic disorders, neurodegeneration, reproductive dysfunction, cancer, and aging." | 5.41 | Beyond Pellagra-Research Models and Strategies Addressing the Enduring Clinical Relevance of NAD Deficiency in Aging and Disease. ( Feuz, MB; Meyer, RG; Meyer-Ficca, ML, 2023) |
| "High doses of niacin (nicotinic acid) used to treat dyslipidemias cause flushing, due to high levels of prostaglandin D(2) (PGD(2))." | 3.77 | High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice. ( Buslon, VS; French, SW; Kwong, AM; Lin, HJ; Materi, AM; Tippin, BL, 2011) |
| "Esophageal cancer deaths between those who did and did not receive factor D were not different overall; however, decreased 17% among participants younger than 55 (HR = 0." | 2.74 | Total and cancer mortality after supplementation with vitamins and minerals: follow-up of the Linxian General Population Nutrition Intervention Trial. ( Abnet, CC; Dawsey, SM; Dong, ZW; Fan, JH; Gail, MH; Johnson, LL; Kamangar, F; Mark, SD; Qiao, YL; Sun, XD; Taylor, PR; Yu, B, 2009) |
| "NAMPT is over-expressed in a number of cancer types such as colorectal, ovarian, breast, gastric, prostate, gliomas as well as B-cell lymphomas." | 2.52 | Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer. ( Dragovich, PS; Misner, DL; O'Brien, T; Sampath, D; Zabka, TS, 2015) |
| "Niacin deficiency has been linked to genomic instability largely through impaired function of the poly ADP-ribose polymerase (PARP) family of enzymes." | 2.48 | Niacin requirements for genomic stability. ( Kirkland, JB, 2012) |
| "In these symptoms, AIDS resembles classical pellagra due to dietary deficiency of Trp and niacin." | 2.38 | Implications of interferon-induced tryptophan catabolism in cancer, auto-immune diseases and AIDS. ( Borden, EC; Brown, RR; Datta, SP; Malone, DG; Ozaki, Y; Sondel, PM, 1991) |
| "Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer patients." | 1.91 | NAD ( Beltrà, M; Corrà, S; Fornelli, C; Hsu, MY; Hulmi, JJ; Kivelä, R; Moletta, L; Penna, F; Pirinen, E; Pöllänen, N; Porporato, PE; Sandri, M; Sartori, R; Tonttila, K; Viscomi, C; Zampieri, S, 2023) |
| "Niacin supplementation improved cancer mortality but not all-cause mortality." | 1.72 | Association between niacin and mortality among patients with cancer in the NHANES retrospective cohort. ( Gao, L; Hong, W; Liao, N; Xu, X; Ying, H; Yu, W, 2022) |
| "Kinases are one of the major players in cancer development and progression." | 1.40 | Identification of novel inhibitors of human Chk1 using pharmacophore-based virtual screening and their evaluation as potential anti-cancer agents. ( Ahmed, S; Gupta, P; Khan, S; Kumar, V; Mishra, DP; Rastogi, N; Siddiqi, MI, 2014) |
| "Analyses of women in the Malmö Diet and Cancer Study showed a mean niacin number of 60." | 1.29 | Niacin deficiency and cancer in women. ( Jacobson, EL, 1993) |
| "Acanthosis nigricans is a reaction pattern to over a dozen different causes." | 1.29 | Acanthosis nigricans--decreased extracellular matrix viscosity: cancer, obesity, diabetes, corticosteroids, somatotrophin. ( Stone, OJ, 1993) |
| "Thymidine deficiency has been reported to increase DNA replication errors and hence increase mutagenesis." | 1.27 | Theoretical involvement of vitamin B6 in tumour initiation. ( Prior, FG, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (59.42) | 18.7374 |
| 1990's | 8 (11.59) | 18.2507 |
| 2000's | 5 (7.25) | 29.6817 |
| 2010's | 9 (13.04) | 24.3611 |
| 2020's | 6 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Brun, EMSP | 1 |
| Calvert, ND | 1 |
| Suchý, M | 1 |
| Kirby, A | 1 |
| Melkus, G | 1 |
| Garipov, R | 1 |
| Addison, CL | 1 |
| Shuhendler, AJ | 1 |
| Ying, H | 1 |
| Gao, L | 1 |
| Liao, N | 1 |
| Xu, X | 1 |
| Yu, W | 1 |
| Hong, W | 1 |
| Beltrà, M | 1 |
| Pöllänen, N | 1 |
| Fornelli, C | 1 |
| Tonttila, K | 1 |
| Hsu, MY | 1 |
| Zampieri, S | 1 |
| Moletta, L | 1 |
| Corrà, S | 1 |
| Porporato, PE | 1 |
| Kivelä, R | 1 |
| Viscomi, C | 1 |
| Sandri, M | 1 |
| Hulmi, JJ | 1 |
| Sartori, R | 1 |
| Pirinen, E | 1 |
| Penna, F | 1 |
| El-Dash, Y | 1 |
| Khalil, NA | 1 |
| Ahmed, EM | 1 |
| Hassanin, SO | 1 |
| Gowifel, AMH | 1 |
| Hassan, MSA | 1 |
| Ghanem, MS | 1 |
| Monacelli, F | 1 |
| Nencioni, A | 1 |
| Lohani, M | 1 |
| Dhasmana, A | 1 |
| Haque, S | 1 |
| Dar, SA | 1 |
| Jawed, A | 1 |
| Wahid, M | 1 |
| Mandal, RK | 1 |
| Akhter, N | 1 |
| Farasani, A | 1 |
| Hobani, YH | 1 |
| Singh, A | 1 |
| Hussain, S | 1 |
| Shames, DS | 1 |
| Elkins, K | 1 |
| Walter, K | 1 |
| Holcomb, T | 1 |
| Du, P | 1 |
| Mohl, D | 1 |
| Xiao, Y | 1 |
| Pham, T | 1 |
| Haverty, PM | 1 |
| Liederer, B | 1 |
| Liang, X | 1 |
| Yauch, RL | 1 |
| O'Brien, T | 2 |
| Bourgon, R | 1 |
| Koeppen, H | 1 |
| Belmont, LD | 1 |
| Kumar, V | 1 |
| Khan, S | 1 |
| Gupta, P | 1 |
| Rastogi, N | 1 |
| Mishra, DP | 1 |
| Ahmed, S | 1 |
| Siddiqi, MI | 1 |
| Sampath, D | 1 |
| Zabka, TS | 1 |
| Misner, DL | 1 |
| Dragovich, PS | 1 |
| Graff, EC | 1 |
| Fang, H | 1 |
| Wanders, D | 1 |
| Judd, RL | 1 |
| Qiao, YL | 1 |
| Dawsey, SM | 1 |
| Kamangar, F | 1 |
| Fan, JH | 1 |
| Abnet, CC | 1 |
| Sun, XD | 1 |
| Johnson, LL | 1 |
| Gail, MH | 1 |
| Dong, ZW | 1 |
| Yu, B | 1 |
| Mark, SD | 1 |
| Taylor, PR | 1 |
| Watson, M | 1 |
| Roulston, A | 1 |
| Bélec, L | 1 |
| Billot, X | 1 |
| Marcellus, R | 1 |
| Bédard, D | 1 |
| Bernier, C | 1 |
| Branchaud, S | 1 |
| Chan, H | 1 |
| Dairi, K | 1 |
| Gilbert, K | 1 |
| Goulet, D | 1 |
| Gratton, MO | 1 |
| Isakau, H | 1 |
| Jang, A | 1 |
| Khadir, A | 1 |
| Koch, E | 1 |
| Lavoie, M | 1 |
| Lawless, M | 1 |
| Nguyen, M | 1 |
| Paquette, D | 1 |
| Turcotte, E | 1 |
| Berger, A | 1 |
| Mitchell, M | 1 |
| Shore, GC | 1 |
| Beauparlant, P | 1 |
| DOBROVOLSKAIA-ZAVADSKAIA, N | 1 |
| Kwong, AM | 1 |
| Tippin, BL | 1 |
| Materi, AM | 1 |
| Buslon, VS | 1 |
| French, SW | 1 |
| Lin, HJ | 1 |
| Kirkland, JB | 2 |
| Prasad, V | 1 |
| Vandross, A | 1 |
| CARRUTHERS, C | 1 |
| SUNTZEFF, V | 1 |
| FORNI, PV | 1 |
| HUANT, E | 1 |
| LEIDER, M | 1 |
| SAWICKY, HH | 1 |
| KAPLAN, NO | 1 |
| GOLDIN, A | 1 |
| HUMPHREYS, SR | 1 |
| CIOTTI, MM | 1 |
| VENDITTI, JM | 1 |
| BERENCSI, G | 1 |
| ENTZ, A | 1 |
| VAJKOCZY, A | 1 |
| TATARSKII, VV | 1 |
| POMPE, K | 1 |
| SHAPIRO, DM | 2 |
| SHILS, ME | 2 |
| FUGMANN, RA | 2 |
| FRIEDLAND, IM | 2 |
| DIETRICH, LS | 3 |
| MARTIN, DS | 2 |
| KLIGERMAN, MM | 1 |
| HOLZER, H | 3 |
| KROGER, H | 1 |
| AURICCHIO, S | 1 |
| QUAGLIARIELLO, E | 3 |
| KAPLAN, LA | 1 |
| TANCREDI, F | 2 |
| FEDELE, L | 2 |
| SACCONE, C | 2 |
| KROEGER, H | 1 |
| ROTTHAUWE, HW | 1 |
| ULRICH, B | 1 |
| MATSUYAMA, M | 1 |
| MAEKAWA, A | 1 |
| NAGAYO, T | 1 |
| ATKINSON, MR | 1 |
| JACKSON, JF | 1 |
| MORTON, RK | 1 |
| FRIEDRICH, G | 1 |
| GRISEBACH, H | 1 |
| AHUJA, JN | 1 |
| TROMOVITCH, TA | 1 |
| JACOBS, PH | 1 |
| KERN, S | 1 |
| DEWEY, DL | 1 |
| HAWES, C | 1 |
| SHIBA, S | 1 |
| TERAWAKI, A | 1 |
| MIYATAKE, M | 1 |
| CLARK, JB | 1 |
| GREENBAUM, AL | 1 |
| MCLEAN, P | 1 |
| REID, E | 1 |
| HILZ, H | 1 |
| BERNDT, H | 1 |
| BARTH, G | 1 |
| GRAEBNER, H | 1 |
| WINTER, M | 1 |
| KERR, WK | 1 |
| BARKIN, M | 1 |
| LEVERS, PE | 1 |
| WOO, SK | 1 |
| MENCZYK, Z | 1 |
| ALTENBRUNN, HJ | 1 |
| STEENBECK, L | 1 |
| EHRHARDT, E | 1 |
| SCHMAGLOWSKI, S | 1 |
| LAW, LW | 1 |
| TING, RC | 1 |
| REDETZKI, HM | 1 |
| O'BOURKE, FA | 1 |
| SCHNEIDER, M | 1 |
| Boovanahalli, SK | 1 |
| Jin, X | 1 |
| Jin, Y | 1 |
| Kim, JH | 1 |
| Dat, NT | 1 |
| Hong, YS | 1 |
| Lee, JH | 1 |
| Jung, SH | 1 |
| Lee, K | 1 |
| Lee, JJ | 1 |
| Kapatsinskiĭ, EV | 1 |
| DiPalma, JR | 1 |
| McMichael, R | 1 |
| Jacobson, EL | 4 |
| Jacobson, MK | 2 |
| Stone, OJ | 1 |
| Bender, DA | 1 |
| Shieh, WM | 1 |
| Huang, AC | 1 |
| Jacob, RA | 1 |
| Schneede, J | 1 |
| Refsum, H | 1 |
| Ueland, PM | 1 |
| Brown, RR | 1 |
| Ozaki, Y | 1 |
| Datta, SP | 1 |
| Borden, EC | 1 |
| Sondel, PM | 1 |
| Malone, DG | 1 |
| Dreizen, S | 1 |
| McCredie, KB | 1 |
| Keating, MJ | 1 |
| Andersson, BS | 1 |
| Jonsson, GG | 1 |
| Prior, FG | 1 |
| Feuz, MB | 1 |
| Meyer-Ficca, ML | 1 |
| Meyer, RG | 1 |
| FABIAN, G | 1 |
| LINKE, H | 1 |
| POLLITZER, RM | 1 |
| TERRIS, M | 1 |
| Lipsett, MB | 1 |
| Walker, AR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nutritional Intervention Trials in Linxian China- Continued Follow-up[NCT00342654] | 34,000 participants (Anticipated) | Observational | 1999-05-20 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for niacin and Benign Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Advances in NAD-Lowering Agents for Cancer Treatment.
Topics: Animals; Antineoplastic Agents; Biosynthetic Pathways; Cell Death; Cell Line, Tumor; Cell Survival; | 2021 |
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Interactions; Drug Resistance, Neopla | 2015 |
Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2.
Topics: Animals; Atherosclerosis; Colitis; Diabetic Retinopathy; Humans; Inflammation; Mice; Neoplasms; Neur | 2016 |
Niacin requirements for genomic stability.
Topics: Animals; Dietary Supplements; DNA Damage; DNA Repair; Genomic Instability; Humans; Models, Animal; N | 2012 |
Niacin and carcinogenesis.
Topics: Adenosine Diphosphate Ribose; Animals; Apoptosis; DNA Repair; Humans; NAD; Neoplasms; Niacin; Nutrit | 2003 |
Tryptophan and niacin nutrition--is there a problem?
Topics: Adult; Animals; Cognition Disorders; Environmental Exposure; Humans; Hydrolases; Iron Deficiencies; | 1996 |
The role of micronutrients in DNA synthesis and maintenance.
Topics: Animals; Ascorbic Acid; DNA; DNA Damage; DNA Repair; Folic Acid; Folic Acid Deficiency; Humans; Neop | 1999 |
Biological and environmental determinants of plasma homocysteine.
Topics: Adult; Aged; Aging; Alcohol Drinking; Child; Cystathionine beta-Synthase; Diagnosis-Related Groups; | 2000 |
Implications of interferon-induced tryptophan catabolism in cancer, auto-immune diseases and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Autoimmune Diseases; Enzyme Induction; Female; Humans; Indoleami | 1991 |
Beyond Pellagra-Research Models and Strategies Addressing the Enduring Clinical Relevance of NAD Deficiency in Aging and Disease.
Topics: Aging; Clinical Relevance; Humans; NAD; Neoplasms; Pellagra | 2023 |
1 trial available for niacin and Benign Neoplasms
| Article | Year |
|---|---|
Total and cancer mortality after supplementation with vitamins and minerals: follow-up of the Linxian General Population Nutrition Intervention Trial.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; alpha-Tocopherol; Antioxidants; Ascorbic Acid; beta Car | 2009 |
57 other studies available for niacin and Benign Neoplasms
| Article | Year |
|---|---|
Mapping vitamin B
Topics: Cell Line, Tumor; Contrast Media; Humans; Hydrazines; Magnetic Resonance Imaging; Neoplasms; Niacin; | 2021 |
Association between niacin and mortality among patients with cancer in the NHANES retrospective cohort.
Topics: Aged; Diet; Female; Humans; Male; Neoplasms; Niacin; Nutrition Surveys; Retrospective Studies; Vitam | 2022 |
NAD
Topics: Animals; Cachexia; Humans; Mice; Muscle, Skeletal; NAD; Neoplasms; Niacin; Niacinamide | 2023 |
Synthesis of novel nicotinic acid derivatives of potential antioxidant and anticancer activity.
Topics: Antineoplastic Agents; Antioxidants; Cell Proliferation; Doxorubicin; Drug Design; Drug Screening As | 2023 |
Niacin deficiency modulates genes involved in cancer: Are smokers at higher risk?
Topics: Carcinogens; Cell Line; Chromosome Aberrations; DNA Damage; DNA Repair; Fetal Research; Fibroblasts; | 2019 |
Loss of NAPRT1 expression by tumor-specific promoter methylation provides a novel predictive biomarker for NAMPT inhibitors.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Cytokines; DNA Methylation; Gene Expression Regulation, Neoplas | 2013 |
Identification of novel inhibitors of human Chk1 using pharmacophore-based virtual screening and their evaluation as potential anti-cancer agents.
Topics: Cell Line, Tumor; Checkpoint Kinase 1; DNA Damage; Humans; Neoplasms; Niacin; Phenylurea Compounds; | 2014 |
The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors.
Topics: Animals; Cell Death; Cell Line, Tumor; Cyanides; Drug Resistance, Neoplasm; Gene Expression Regulati | 2009 |
The effect of nicotinamide (vitamin P.P.) on tumor growth in mice.
Topics: Adrenal Glands; Animals; Neoplasms; Neoplasms, Experimental; Niacin; Nicotinic Acids | 1945 |
High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.
Topics: Adenoma; Animals; Cyclin D1; Diet; Dose-Response Relationship, Drug; Female; Flushing; Humans; Intes | 2011 |
Cardiovascular primary prevention: how high should we set the bar?
Topics: Anticholesteremic Agents; Azetidines; Biomarkers; Cardiovascular Diseases; Cholesterol, LDL; Cost-Be | 2012 |
Nicotinamide content of some normal and malignant tissues; the apparent absence of niacin in epidermis.
Topics: Epidermis; Neoplasms; Niacin; Niacinamide; Nicotinic Acids | 1952 |
[Isonicotinic acid hydrazide and neoplasia].
Topics: Animals; Isomerism; Isoniazid; Neoplasms; Neoplasms, Experimental; Niacin; Nicotinic Acids | 1952 |
[Utility of oxidoreductive vitamins (PP, C and B complex) in cancer therapy].
Topics: Ascorbic Acid; Folic Acid; Humans; Neoplasms; Niacin; Nicotinic Acids; Vitamin A; Vitamin B Complex; | 1953 |
Therapeutic assays of the Skin and Cancer Unit of the New York University Hospital. VIII. Isonicotinylhydrazine (rimifon) in the treatment of tuberculosis cutis, some other granulomatous processes and miscellaneous dermatoses of doubtful cause.
Topics: Hospitals, University; Isoniazid; Neoplasms; New York; Niacin; Nicotinic Acids; Skin Diseases; Tuber | 1953 |
Significance of enzymatically catalyzed exchange reactions in chemotherapy.
Topics: Animals; Coenzymes; Liver; Mice; Neoplasms; Niacin; Niacinamide; Nicotinic Acids; Pyridines; Tryptop | 1954 |
[Isoniazid therapy and cancer of lungs].
Topics: Isomerism; Isoniazid; Lung Neoplasms; Neoplasms; Niacin; Nicotinic Acids | 1955 |
[Methylated nicotinamide in the liver in neoplasms in rats].
Topics: Animals; Liver; Neoplasms; Niacin; Niacinamide; Nicotinic Acids; Rats | 1955 |
[Effects of isoniazid on pathogenesis of lupus carcinoma].
Topics: Carcinoma; Isomerism; Isoniazid; Lupus Vulgaris; Neoplasms; Niacin; Nicotinic Acids | 1956 |
Quantitative biochemical differences between tumor and host as a basis for cancer chemotherapy. IV. Niacin and 2-ethylamino-1, 3, 4-thiadiazole.
Topics: Heterocyclic Compounds; Humans; Neoplasms; Niacin; Nicotinic Acids; Thiadiazoles | 1957 |
Quantitative biochemical differences between tumor and host as a basis for cancer chemotherapy. V. Niacin and 6-aminonicotinamide.
Topics: 6-Aminonicotinamide; Antineoplastic Agents; Humans; Neoplasms; Niacin; Nicotinic Acids | 1957 |
Radiotherapy and adjuvant combination chemotherapy (6-aminonicotinamide and 6-mercaptopurine).
Topics: 6-Aminonicotinamide; Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Chemotherapy, Adjuvant; Drug T | 1958 |
[Mechanism of action of B 518 (endoxan-Asia) jensen sarcoma and inhibition of chemotherapy of tumors by the vitamin nicotine acid amide].
Topics: Amides; Animals; Asia; Cyclophosphamide; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Niacin | 1958 |
[Biochemical defects in the tryptophan-nicotinic acid metabolic system. II].
Topics: Biochemical Phenomena; Encephalomyelitis; Neoplasms; Niacin; Nicotinic Acids; Tryptophan | 1958 |
Quantitative biochemical differences between tumor and host tissue. VI. 6-Aminonicotinamide antagonism of DPN-dependent enzymatic systems.
Topics: 6-Aminonicotinamide; Antineoplastic Agents; Coenzymes; NAD; Neoplasms; Niacin; Nicotinic Acids | 1958 |
Tryptophan-nicotinic acid metabolism in patients with tumours of the bladder. Changes in the excretory products after treatment with nicotinamide and vitamin B6.
Topics: Humans; Neoplasms; Niacin; Niacinamide; Nicotinic Acids; Tryptophan; Urinary Bladder Neoplasms; Vita | 1961 |
[Studies on the metabolic conversion of tryptophan into nicotinic acid in individuals with tumors of the bladder. Modifications in the urinary excretory picture after the administration of nicotinamide and vitamin B6].
Topics: Humans; Neoplasms; Niacin; Niacinamide; Nicotinic Acids; Tryptophan; Urinary Bladder Neoplasms; Vita | 1960 |
[On the influence of carcinostatic agents on the DPN metabolism of tumors. I. Incorporation of C-14-ribose and C-14-nicotinamide into the DPN of ascites cells].
Topics: Antineoplastic Agents; Ascites; Coenzymes; NAD; Neoplasms; Niacin; Niacinamide; Nicotinic Acids; Rib | 1960 |
Inhibiting effect of nicotinamide and diphosphopyridine nucleotide on the methylcholanthrene sarcoma in rats.
Topics: Animals; Coenzymes; Methylcholanthrene; NAD; Neoplasms; Niacin; Niacinamide; Nicotinic Acids; Rats; | 1961 |
Substrate specificity and inhibition of nicotinamide mononucleotideadenylyl transferase of liver nuclei: possible mechanism of effect of 6-mercaptopurine on tumour growth.
Topics: Cell Nucleus; Liver; Mercaptopurine; Neoplasms; Niacin; Niacinamide; Substrate Specificity; Transfer | 1961 |
[Evaluation of nicotinic acid and nicotinamide for the biosynthesis of DPN in ascites tumor cells].
Topics: Ascites; Coenzymes; NAD; Neoplasms; Niacin; Niacinamide; Nicotinic Acids | 1961 |
Uptake of nicotinic acid-C-14 and nicotinamide-C-14 by ascites cells in vitro.
Topics: Ascites; In Vitro Techniques; NAD; Neoplasms; Neoplasms, Experimental; Niacin; Niacinamide; Nicotini | 1963 |
ACANTHOSIS NIGRICANS-LIKE LESIONS FROM NICOTINIC ACID.
Topics: Acanthosis Nigricans; Adenocarcinoma; Diagnosis, Differential; Diethylstilbestrol; Humans; Hyperchol | 1964 |
6-AMINONICOTINAMIDE AND THE RADIOSENSITIVITY OF HUMAN LIVER CELLS IN CULTURE.
Topics: 6-Aminonicotinamide; Animals; Carcinoma, Ehrlich Tumor; Chromosomes; Fetus; Liver; Mice; Neoplasms; | 1963 |
STUDIES ON THE TRYPTOPHAN METABOLISM IN TUMOR-BEARING ANIMALS.
Topics: Animals; Kynurenic Acid; Kynurenine; Liver; Neoplasms; Neoplasms, Experimental; Niacin; Nicotinic Ac | 1964 |
CONCENTRATIONS AND RATES OF SYNTHESIS OF NICOTINAMIDE-ADENINE-DINUCLEODIDE PHOSPHATE IN PRECANCEROUS LIVERS AND HEPATOMAS INDUCED BY AZO-DYE FEEDING.
Topics: Adenine; Carcinogens; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; NADP; Neoplasms; Neoplasms, | 1964 |
[THE PROTECTIVE EFFECT OF NICOTINAMIDE ON RADIATION-INDUCED INJURY OF DNA SYNTHESIS AS A CELL POPULATION PROBLEM].
Topics: Animals; Carbohydrate Metabolism; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; NAD; Neoplasm Protei | 1964 |
[SUPPLEMENTARY MEDICAL TREATMENT OF THE TUMOR BED. 8. ANIMAL EXPERIMENTAL STUDIES ON THE PROBLEM OF PARATUMORAL AND TUMOR-REMOTE NICOTINIC ACID EFFECT ON CROCKER SARCOMA 180 UNDER OPTIMUM ROENTGEN IRRADIATION].
Topics: Animal Experimentation; Animals; Mice; Neoplasms; Niacin; Pathology; Pharmacology; Radiation Effects | 1965 |
THE EFFECT OF CIGARETTE SMOKING ON BLADDER CARCINOGENS IN MAN.
Topics: Amino Acids; Carcinogens; Humans; Male; Metabolism; Neoplasms; Niacin; Niacinamide; Nicotiana; Smoki | 1965 |
[INVESTIGATION ON THE DECREASE IN CONCENTRATION OF NAD IN LYMPHOSARCOMA ASCITES CELLS FOLLOWING X-IRRADIATION].
Topics: Ascites; Chromatography; Lymphoma; Lymphoma, Non-Hodgkin; Metabolism; NAD; Neoplasms; Neoplasms, Exp | 1965 |
IMMUNOLOGIC COMPETENCE AND INDUCTION OF NEOPLASMS BY POLYOMA VIRUS.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dogs; Fatty Acids; Immunocompe | 1965 |
Influence of nicotic acid and nicotinamide on diphosphopyridine nucleotide (DPN) Synthesis in ascites tumor cells.
Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Coenzymes; NAD; Neoplasms; Niacin; Niacinamide; Nicotini | 1961 |
Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hypoxi | 2007 |
[Prevention of thromboembolic complications in cancer patients].
Topics: Anticoagulants; Blood Coagulation; Heparin; Humans; Neoplasms; Niacin; Thromboembolism | 1983 |
Assessing the value of meganutrients in disease.
Topics: Animals; Ascorbic Acid; Cats; Common Cold; Diet Fads; Humans; Mental Disorders; Neoplasms; Niacin; O | 1982 |
Niacin deficiency and cancer in women.
Topics: Diet; Female; Follow-Up Studies; Humans; Male; Middle Aged; NAD; NADP; Neoplasms; Niacin; Nutritiona | 1993 |
A biomarker for the assessment of niacin nutriture as a potential preventive factor in carcinogenesis.
Topics: Adenosine Diphosphate Ribose; Biomarkers; Blood Cells; DNA Damage; DNA Repair; Humans; NAD; NADP; Ne | 1993 |
Acanthosis nigricans--decreased extracellular matrix viscosity: cancer, obesity, diabetes, corticosteroids, somatotrophin.
Topics: Acanthosis Nigricans; Adrenal Cortex Hormones; Diabetes Complications; Extracellular Matrix; Female; | 1993 |
Mapping the role of NAD metabolism in prevention and treatment of carcinogenesis.
Topics: Animals; Breast Neoplasms; Humans; Lung Neoplasms; NAD; Neoplasms; Niacin; Rats; Skin; Skin Neoplasm | 1999 |
Nutritional deficiencies in patients receiving cancer chemotherapy.
Topics: Antineoplastic Agents; Cachexia; Folic Acid Deficiency; Humans; Hypoproteinemia; Methotrexate; Neopl | 1990 |
[The B vitamin niacin and its potential role in cellular defense against DNA damage].
Topics: Animals; DNA; DNA, Neoplasm; Humans; Neoplasms; Niacin; Pellagra | 1987 |
Theoretical involvement of vitamin B6 in tumour initiation.
Topics: DNA; DNA Repair; Estrogens; Female; Folic Acid Deficiency; Humans; Isoniazid; Neoplasms; Niacin; Thy | 1985 |
[Clinical aspects of secondary pellagra].
Topics: Digestive System Neoplasms; Folic Acid; Gastrointestinal Tract; Humans; Liver Cirrhosis; Neoplasms; | 1954 |
Morbidity and mortality changes in South Carolina since 1919.
Topics: Accidents; Accidents, Traffic; Ancylostomatoidea; Animals; Communicable Diseases; Heart Diseases; Hu | 1963 |
EPIDEMIOLOGIC APPROACH TO CHRONIC DISEASES.
Topics: Chronic Disease; Coronary Disease; Dental Caries; Epidemiology; History; Humans; Lung Neoplasms; Neo | 1964 |
Effects of cancers of the endocrine and central nervous systems on nutritional status.
Topics: Brain Neoplasms; Calcitonin; Cholesterol; Diarrhea; Endocrine Glands; Gastrins; Gastrointestinal Hor | 1977 |
Biological and disease patterns in South African inter-racial populations as modified by rise in privilege.
Topics: Adult; Aged; Blood Pressure; Body Weight; Cerebrovascular Disorders; Cholesterol; Coronary Disease; | 1972 |