niacin has been researched along with Arterial Occlusive Diseases in 12 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niacin has potentially favourable effects on lipids, but its effect on cardiovascular outcomes is uncertain." | 2.78 | HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment. ( , 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Landmesser, U | 1 |
| Rosenson, RS | 1 |
| Gotto, AM | 1 |
| Tofield, A | 1 |
| Nicholls, SJ | 1 |
| Il'in, VN | 1 |
| Stepanov, NV | 1 |
| Ikhaev, ZA | 1 |
| Sharonin, GV | 1 |
| Bogdanets, LI | 1 |
| Kuo, PT | 1 |
| Kostis, JB | 2 |
| Moreyra, AE | 1 |
| Mund-Hoym, WD | 1 |
| Riasina, TV | 1 |
| Korshunova, TS | 1 |
| Polianskiĭ, NB | 1 |
| Muranov, KO | 1 |
| Philipp, CS | 1 |
| Cisar, LA | 1 |
| Saidi, P | 1 |
| Chesney, CM | 1 |
| Elam, MB | 1 |
| Herd, JA | 1 |
| Davis, KB | 1 |
| Garg, R | 1 |
| Hunninghake, D | 1 |
| Kennedy, JW | 1 |
| Applegate, WB | 1 |
| Kostiunin, VN | 1 |
| Pakhomov, VI | 1 |
| Feoktistov, PL | 1 |
| Petrova, EA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000539] | Phase 3 | 0 participants | Interventional | 1992-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for niacin and Arterial Occlusive Diseases
| Article | Year |
|---|---|
HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment.
Topics: Arterial Occlusive Diseases; Chemical and Drug Induced Liver Injury; Death, Sudden, Cardiac; Delayed | 2013 |
Effect of niacin supplementation on fibrinogen levels in patients with peripheral vascular disease.
Topics: Adult; Antioxidants; Arterial Occlusive Diseases; Cholesterol, HDL; Cholesterol, LDL; Dose-Response | 1998 |
Effect of niacin, warfarin, and antioxidant therapy on coagulation parameters in patients with peripheral arterial disease in the Arterial Disease Multiple Intervention Trial (ADMIT).
Topics: Aged; Anticoagulants; Antioxidants; Arterial Occlusive Diseases; Ascorbic Acid; beta Carotene; Blood | 2000 |
9 other studies available for niacin and Arterial Occlusive Diseases
| Article | Year |
|---|---|
The difficult search for a 'partner' of statins in lipid-targeted prevention of vascular events: the re-emergence and fall of niacin.
Topics: Arterial Occlusive Diseases; Chemical and Drug Induced Liver Injury; Female; Humans; Hypolipidemic A | 2013 |
When clinical trials fail to address treatment gaps: the failure of niacin-laropiprant to reduce cardiovascular events.
Topics: Arterial Occlusive Diseases; Chemical and Drug Induced Liver Injury; Female; Humans; Hypolipidemic A | 2013 |
Niacin and statin intolerable for some people.
Topics: Arterial Occlusive Diseases; Clinical Trials as Topic; Delayed-Action Preparations; Drug Eruptions; | 2013 |
Niacin's effect on cardiovascular risk: have we finally learned our lesson?
Topics: Arterial Occlusive Diseases; Atherosclerosis; Chemical and Drug Induced Liver Injury; Cholesterol, H | 2014 |
[Postoperative antithrombotic therapy in acute occlusion of the major arteries of the extremities].
Topics: Acute Disease; Adolescent; Adult; Aged; Arm; Arterial Occlusive Diseases; Aspirin; Dextrans; Female; | 1980 |
Protection of myocardium by the compensatory mechanism of coronary collaterals after total occlusion of major coronary arteries shown in patients with familial hypercholesterolemia.
Topics: Adult; Arterial Occlusive Diseases; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Colestipol; | 1982 |
[Peripheral arterial occlusive disorders].
Topics: Arterial Occlusive Diseases; Delayed-Action Preparations; Humans; Niacin | 1982 |
[Anti-ischemic effect of a new derivative of oxynicotinic acid].
Topics: Animals; Arterial Occlusive Diseases; Brain Ischemia; Carotid Artery Diseases; Free Radicals; Lipid | 1994 |
[Increasing the effectiveness of hyperbaric oxygenation in the treatment of patients with stage IV arterial occlusive diseases of the lower limbs].
Topics: Arterial Occlusive Diseases; Combined Modality Therapy; Dextrans; Follow-Up Studies; Humans; Hyperba | 1985 |