niacin and Adenoma
niacin has been researched along with Adenoma in 4 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Adenoma: A benign epithelial tumor with a glandular organization.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "2 mg riboflavin, 80 mg niacin, 60 mg zinc, 5 mg manganese) given daily over 4 months on oxidative and inflammatory biomarkers in patients with a history of sporadic colorectal adenoma." | 5.14 | Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial. ( Bostick, RM; Fedirko, V; Hopkins, MH; Jones, DP; Terry, PD, 2010) |
| "In acromegalic patients acute pharmacological reduction of FFA with acipimox did not modify basal GH levels or GHRH-induced GH secretion, suggesting that the adenomatous somatotroph cell is unresponsive to physiological signals such as FFA which act at a pituitary level." | 5.09 | Effect of acute pharmacological modulation of plasma free fatty acids on GH secretion in acromegalic patients. ( Casanueva, FF; Cordido, F; Dieguez, C; Martinez, T; Peñalva, A, 2001) |
| "High doses of niacin (nicotinic acid) used to treat dyslipidemias cause flushing, due to high levels of prostaglandin D(2) (PGD(2))." | 3.77 | High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice. ( Buslon, VS; French, SW; Kwong, AM; Lin, HJ; Materi, AM; Tippin, BL, 2011) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hopkins, MH | 1 |
| Fedirko, V | 1 |
| Jones, DP | 1 |
| Terry, PD | 1 |
| Bostick, RM | 1 |
| Kwong, AM | 1 |
| Tippin, BL | 1 |
| Materi, AM | 1 |
| Buslon, VS | 1 |
| French, SW | 1 |
| Lin, HJ | 1 |
| Hotz, KJ | 1 |
| Wilson, AG | 1 |
| Thake, DC | 1 |
| Roloff, MV | 1 |
| Capen, CC | 1 |
| Kronenberg, JM | 1 |
| Brewster, DW | 1 |
| Cordido, F | 1 |
| Peñalva, A | 1 |
| Martinez, T | 1 |
| Casanueva, FF | 1 |
| Dieguez, C | 1 |
Trials
2 trials available for niacin and Adenoma
| Article | Year |
|---|---|
Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial.
Topics: Adenoma; Adult; Aged; Antioxidants; Ascorbic Acid; beta Carotene; Biomarkers, Tumor; Chromatography, | 2010 |
Effect of acute pharmacological modulation of plasma free fatty acids on GH secretion in acromegalic patients.
Topics: Acromegaly; Adenoma; Area Under Curve; Fatty Acids, Nonesterified; Feedback; Female; Growth Hormone; | 2001 |
Other Studies
2 other studies available for niacin and Adenoma
| Article | Year |
|---|---|
High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.
Topics: Adenoma; Animals; Cyclin D1; Diet; Dose-Response Relationship, Drug; Female; Flushing; Humans; Intes | 2011 |
Mechanism of thiazopyr-induced effects on thyroid hormone homeostasis in male Sprague-Dawley rats.
Topics: Adenoma; Animals; Bile; Diet; Dose-Response Relationship, Drug; Enzyme Induction; Glucuronosyltransf | 1997 |