niacin has been researched along with Acute Confusional Senile Dementia in 12 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niacin (vitamin B3) is an essential nutrient that treats pellagra, and prior to the advent of statins, niacin was commonly used to counter dyslipidemia." | 5.41 | The Promise of Niacin in Neurology. ( Urgoiti, GR; Wuerch, E; Yong, VW, 2023) |
| "Niacin serves as a high-affinity ligand for the receptor HCAR2 (GPR109A)." | 1.72 | The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease. ( Casali, BT; Coronel, I; Lamb, BT; Landreth, GE; Lasagna-Reeves, CA; Lin, PB; Martinez, P; Moutinho, M; Oblak, AL; Puntambekar, SS; Tsai, AP, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moutinho, M | 1 |
| Puntambekar, SS | 1 |
| Tsai, AP | 1 |
| Coronel, I | 1 |
| Lin, PB | 1 |
| Casali, BT | 1 |
| Martinez, P | 1 |
| Oblak, AL | 1 |
| Lasagna-Reeves, CA | 1 |
| Lamb, BT | 1 |
| Landreth, GE | 1 |
| Wuerch, E | 1 |
| Urgoiti, GR | 1 |
| Yong, VW | 1 |
| Hosseini, L | 1 |
| Mahmoudi, J | 1 |
| Pashazadeh, F | 1 |
| Salehi-Pourmehr, H | 1 |
| Sadigh-Eteghad, S | 1 |
| Qin, B | 1 |
| Xun, P | 1 |
| Jacobs, DR | 1 |
| Zhu, N | 1 |
| Daviglus, ML | 1 |
| Reis, JP | 1 |
| Steffen, LM | 1 |
| Van Horn, L | 1 |
| Sidney, S | 1 |
| He, K | 1 |
| Szymański, P | 1 |
| Markowicz, M | 1 |
| Mikiciuk-Olasik, E | 1 |
| Lee, ST | 1 |
| Chu, K | 1 |
| Jung, KH | 1 |
| Kim, JH | 1 |
| Huh, JY | 1 |
| Yoon, H | 1 |
| Park, DK | 1 |
| Lim, JY | 1 |
| Kim, JM | 1 |
| Jeon, D | 1 |
| Ryu, H | 1 |
| Lee, SK | 1 |
| Kim, M | 1 |
| Roh, JK | 1 |
| Vega, GL | 2 |
| Weiner, MF | 1 |
| Lipton, AM | 1 |
| Von Bergmann, K | 1 |
| Lutjohann, D | 1 |
| Moore, C | 1 |
| Svetlik, D | 1 |
| Baskin, F | 1 |
| Rosenberg, RN | 1 |
| Fang, X | 1 |
| Hynan, LS | 1 |
| Moore, CB | 1 |
| Weiner, M | 1 |
| Morris, MC | 1 |
| Evans, DA | 1 |
| Bienias, JL | 1 |
| Scherr, PA | 1 |
| Tangney, CC | 1 |
| Hebert, LE | 1 |
| Bennett, DA | 1 |
| Wilson, RS | 1 |
| Aggarwal, N | 1 |
| Hankes, LV | 1 |
| Coenen, HH | 1 |
| Rota, E | 1 |
| Langen, KJ | 1 |
| Herzog, H | 1 |
| Wutz, W | 1 |
| Stoecklin, G | 1 |
| Feinendegen, LE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-blind, Placebo-controlled, Crossover Study to Investigate the Safety and Efficacy of Qualia Mind on Cognition in a Healthy Population[NCT04389723] | 60 participants (Actual) | Interventional | 2020-05-12 | Completed | |||
| Research of Olfactory Neuroepithelial Tissue as a Potential Biomarker of Alzheimer Disease[NCT02129452] | 40 participants (Actual) | Observational | 2013-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for niacin and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
The Promise of Niacin in Neurology.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Nervous System Diseases; Neurology; Niacin; Pellag | 2023 |
Protective Effects of Nicotinamide Adenine Dinucleotide and Related Precursors in Alzheimer's Disease: A Systematic Review of Preclinical Studies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Apoptosis; Behavior, An | 2021 |
2 trials available for niacin and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease.
Topics: Aged; Alzheimer Disease; Brain; Cholesterol 24-Hydroxylase; Female; Humans; Hydroxycholesterols; Hyd | 2003 |
Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Blood Platelets; Cholester | 2003 |
8 other studies available for niacin and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Disease Progression; Mice | 2022 |
Intake of niacin, folate, vitamin B-6, and vitamin B-12 through young adulthood and cognitive function in midlife: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Topics: Adult; Age Factors; Alzheimer Disease; Cognition; Cognition Disorders; Cohort Studies; Diet; Dietary | 2017 |
Synthesis and biological activity of derivatives of tetrahydroacridine as acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Cholinesterase Inhibitors; Enzyme Activation; Hu | 2011 |
miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model.
Topics: Alzheimer Disease; Animals; Benzylamines; Brain; Brain-Derived Neurotrophic Factor; Dendritic Spines | 2012 |
Dietary niacin and the risk of incident Alzheimer's disease and of cognitive decline.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Diet; Female; Humans; Hypolipidemic Agents; Male; Niac | 2004 |
Brain bonus with niacin?
Topics: Alzheimer Disease; Humans; Hypolipidemic Agents; Memory Disorders; Niacin; Vasodilator Agents | 2004 |
Researchers study effect of niacin on Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Food; Humans; Niacin | 2005 |
Effect of Huntington's and Alzheimer's diseases on the transport of nicotinic acid or nicotinamide across the human blood-brain barrier.
Topics: Alzheimer Disease; Blood-Brain Barrier; Brain; Humans; Huntington Disease; Niacin; Niacinamide; Tomo | 1991 |