ngr-peptide and Ovarian-Neoplasms

ngr-peptide has been researched along with Ovarian-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for ngr-peptide and Ovarian-Neoplasms

Article	Year
Radiolabeled NGR phage display peptide sequence for tumor targeting. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 86 The asparagine-glycine-arginine (NGR) peptide sequence found by phage display, was radiolabeled with technetium-99m and tested in different tumor models. Similar uptake occurred with ovarian and lung tumor cells. Biodistribution of the radiotracer revealed predominant renal excretion with more substantial uptake in animals bearing ovarian tumor cells. In contrast imaging studies indicated better visualization for lung tumor. NGR peptide was characterized as a promising diagnostic candidate, particularly for lung cancer. Improvements are envisaged using NGR combined with RGD as a heterodimer molecule. Topics: Animals; Cell Line, Tumor; Female; Lung Neoplasms; Male; Mice; Neoplasms; Oligopeptides; Ovarian Neoplasms; Peptide Library; Radiopharmaceuticals; Technetium	2014

Article

Year

Radiolabeled NGR phage display peptide sequence for tumor targeting.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 86

The asparagine-glycine-arginine (NGR) peptide sequence found by phage display, was radiolabeled with technetium-99m and tested in different tumor models. Similar uptake occurred with ovarian and lung tumor cells. Biodistribution of the radiotracer revealed predominant renal excretion with more substantial uptake in animals bearing ovarian tumor cells. In contrast imaging studies indicated better visualization for lung tumor. NGR peptide was characterized as a promising diagnostic candidate, particularly for lung cancer. Improvements are envisaged using NGR combined with RGD as a heterodimer molecule.

Topics: Animals; Cell Line, Tumor; Female; Lung Neoplasms; Male; Mice; Neoplasms; Oligopeptides; Ovarian Neoplasms; Peptide Library; Radiopharmaceuticals; Technetium

2014