ng-nitroarginine methyl ester has been researched along with Pulmonary Hypertension in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 34 (39.53) | 18.2507 |
| 2000's | 39 (45.35) | 29.6817 |
| 2010's | 12 (13.95) | 24.3611 |
| 2020's | 1 (1.16) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, C; Chen, A; Han, Y; Liang, S; Pan, Y; Tang, H; Wang, X | 1 |
| Li, G; Liu, Y; Yan, D; Zhang, H; Zhang, Y; Zhao, L | 1 |
| Abe, K; Hoka, S; Ishikawa, T; McMurtry, IF; Oka, M; Saku, K; Sunagawa, K; Tanaka, M; Tsutsui, H; Yoshida, K | 1 |
| Adthapanyawanich, K; Chootip, K; Demougeot, C; Ingkaninan, K; Temkitthawon, P; Totoson, P; Wisutthathum, S | 1 |
| Kim, SH; Lee, GJ; Li, W; Park, BM; Yu, L | 1 |
| Gong, QH; Huang, XN; Qin, N; Wei, LW; Wu, Q | 1 |
| Decante, B; Dorfmuller, P; Eddahibi, S; Herve, P; Humbert, M; Le Pavec, J; Lebrec, D; Mazmanian, M; Perros, F; Sitbon, O | 1 |
| Dackor, RT; Li, R; Ma, B; Tu, L; Wang, DW; Wang, L; Xu, X; Zeldin, DC; Zheng, C | 1 |
| Khromov, OS; Strielkov, IeV | 1 |
| Kumar, VH; Lakshminrusimha, S; Ma, C; Morin, FC; Rashid, N; Ryan, RM; Swartz, DD | 1 |
| Ishibashi-Ueda, H; Kangawa, K; Pearson, JT; Schwenke, DO; Shimouchi, A; Shirai, M; Sonobe, T; Umetani, K | 1 |
| Badejo, AM; Bhartiya, M; Haider, U; Kadowitz, PJ; Murthy, SN; Nossaman, BD; Pankey, EA; Stasch, JP | 1 |
| Artuković, B; Cenan, S; Cooper, RG; Dinarina-Sablić, M; Dzaja, P; Grabarević, Z; Tisljar, M; Zelenika, TA | 1 |
| Hirata, Y; Morita, T; Nagai, R; Sahara, M; Sata, M | 1 |
| Badejo, AM; Bhartiya, M; Bueno, FR; Byun, RJ; Kadowitz, PJ; Murthy, SN; Nossaman, BD; Pankey, EA; Smith, WB; Stasch, JP | 1 |
| Baelde, HJ; de Visser, YP; Laghmani, el H; Sengers, RM; Steendijk, P; Wagenaar, GT; Walther, FJ | 1 |
| Sun, W; Wang, J; Wang, X; Xiang, R | 1 |
| Ambalavanan, N; Bulger, A; Chen, YF; Oparil, S; Philips, JB | 1 |
| Konduri, GG; Ou, J; Pritchard, KA; Shi, Y | 1 |
| Amtorp, O; Boberg, B; Ravn, JB; Sander, M; Welling, KL | 1 |
| Cheng, X; Leung, SW; Lim, SL; Pang, CC | 1 |
| Du, JB; Shi, L; Tang, CS; Yan, H; Zhang, CY; Zhang, QY | 1 |
| Chapman, ME; Wideman, RF | 1 |
| Makita, T; Shibata, O; Sumikawa, K; Tsutsumi, Y; Yamaguchi, K | 1 |
| Bloch, KD; Chang, Y; Evgenov, NV; Evgenov, OV; Falkowski, GE; Gnoth, MJ; Ichinose, F; Zapol, WM | 1 |
| Deuchar, GA; Hicks, MN; MacLean, MR | 1 |
| Gerlach, RF; Metzger, IF; Rocha, JB; Souza-Costa, DC; Tanus-Santos, JE; Zerbini, T | 1 |
| Ascuitto, RJ; Baber, SR; Kadowitz, PJ; Li, H; Ross-Ascuitto, NT; Simakajornboon, N | 1 |
| Chang, HY; Chen, CW; Hsiue, TR; Kuo, YL; Lee, CH; Wang, CM | 1 |
| Chapman, ME; Erf, GF; Wideman, RF | 1 |
| Banasová, A; Bíbová, J; Hampl, V; Herget, J; Hnilicková, O; Lachmanová, V; Miková, D; Uhlík, J | 1 |
| Chu, SJ; Lee, TY; Li, MH; Lin, SH; Yan, HC | 1 |
| Ku, DD; Sun, X | 1 |
| Mori, H; Pearson, JT; Schwenke, DO; Shirai, M; Tsuchimochi, H | 1 |
| Anthony, NB; Bowen, OT; Erf, GF; Wideman, RF | 1 |
| Kim, TJ; Koriyama, T; Kusuda, S; Matsunami, S; Nakanishi, H | 1 |
| Endo, K; Hirota, M; Inai, Y; Iwasaki, T; Kajiya, F; Kajiya, M; Kiyooka, T; Mohri, S; Morimoto, T; Naruse, K; Ogasawara, Y; Ohe, T; Shimizu, J; Yada, T | 1 |
| Kukreja, RC | 1 |
| Koizumi, T; Kubo, K; Ruan, Z; Sakai, A; Shibamoto, T; Watanabe, K | 1 |
| Allières, C; Banquet, S; Bégueret, H; Bellance, N; Delannoy, E; Desgranges, C; Fresquet, F; Gadeau, A; Leblais, V; Leroux, L; Muller, B | 1 |
| Braun-Dullaeus, RC; Ebner, B; Heerwagen, C; Kasper, M; Morawietz, H; Schmeisser, A; Schober, K; Schwencke, C; Strasser, RH; Wunderlich, C | 1 |
| Archer, SL; Hampl, V; Nelson, DP; Weir, EK | 1 |
| Barer, G; Howard, P; Kapeller, K; Russell, P; Wright, C | 1 |
| Berger, JI; Gibson, RL; Mayock, DE; Redding, GJ; Standaert, TA; Truog, WE | 1 |
| Hughes, IE; O'Donnell, SR; Wanstall, JC | 1 |
| Kavanagh, BP; Lindeborg, DM; Pearl, RG; Van Meurs, K | 1 |
| Cao, W; Zeng, Z; Zhu, Y | 1 |
| Cao, WB; Luo, WC; Zhu, YJ | 1 |
| Cioffi, WG; Johnson, AA; Jordan, BS; Offner, PJ; Ogura, H; Pruitt, BA; Saitoh, D | 1 |
| Pearl, RG; Xu, H | 1 |
| Lipsitz, EC; Smerling, AJ; Stolar, CJ; Weinstein, S | 1 |
| Baird, M; MacLean, MR; McCulloch, KM | 1 |
| Cioffi, WG; Jordan, BS; Offner, PJ; Ogura, H; Pruitt, BA | 1 |
| Kavanagh, BP; Pearl, RG; Thompson, JS | 1 |
| Archer, SL; Hampl, V; Huang, JM; Michelakis, E; Nelson, DP; Reeve, HL; Weir, EK | 1 |
| Itoh, A; Kondo, M; Matsukura, Y; Motoyoshi, S; Nakajyo, S; Shimizu, K; Urakawa, N; Washizu, M | 1 |
| Adnot, S; Aegerter, P; Eddahibi, S; Launay, JM; Pham, I; Raffestin, B; Sitbon, M | 1 |
| Albenque, JP; Balanescu, S; Bounhoure, JP; Doazan, JP; Fourcade, J; Galinier, M; Montastruc, JL; Montastruc, P; Rougé, P; Senard, JM | 1 |
| Koyama, S; Matsuda, Y; Shibamoto, T; Wang, HG | 1 |
| MacLean, MR; McCulloch, KM | 1 |
| Norberg, M; Thibeault, DW; Truog, WE | 1 |
| Champion, HC; Gumusel, B; Hao, Q; Hyman, AL; Kadowitz, PJ; Lippton, H; Tower, A | 1 |
| Goetz, TE; Manohar, M | 1 |
| Avontuur, JA; Biewenga, M; Bruining, HA; Buijk, SL; Kanhai, KJ | 1 |
| Abdel-Razek, TT; Abrams, GA; Chen, SJ; Chen, YF; Dai, J; Fallon, MB; Ku, DD; Luo, B; Oparil, S | 1 |
| Barer, GR; Kapeller, K; Russell, PC | 1 |
| Kavanagh, BP; Patterson, KW; Pearl, RG; Wall, MH | 1 |
| Blomquist, S; Dahm, PL; Grins, E; Mårtensson, L; Myhre, E; Thörne, J | 1 |
| Blaise, G | 1 |
| Becker, EJ; Hester, RK; Jeffrey, JS; Martinez-Lemus, LA; Odom, TW | 1 |
| Arnal, JF; Darblade, B; Dinh-Xuan, AT; Pueyo, M; Rami, J | 1 |
| Bower, EA; Cremona, G; Higenbottam, TW; Stewart, S; Wood, AM | 1 |
| Frank, DU; Horstman, DJ; McCall, DA; Rich, GF | 1 |
| Archer, SL; Cornfield, DN; Hampl, V; Martin, EB | 1 |
| Bivalacqua, TJ; Champion, HC; Heistad, DD; Hyman, AL; Kadowitz, PJ; Toyoda, K | 1 |
| Alexander, D; Douglas, SA; Gallagher, M; MacLean, MR; Morecroft, I; Ohlstein, EH; Polland, K; Stirrat, A | 1 |
| Bloch, KD; Clark, MW; Fujino, Y; Hromi, J; Ullrich, R; Weimann, J; Zapol, WM | 1 |
| Anwar, M; De Witt, BJ; Feng, CJ; Kadowitz, PJ; Kaye, AD; Nossaman, BD; Smith, DE | 1 |
| Bradford, KK; Deb, B; Pearl, RG | 1 |
| Kim-Park, S; Ku, DD | 1 |
| Blumberg, FC; Lorenz, C; Pfeifer, M; Riegger, GA; Sandner, P; Wolf, K | 1 |
| Hayashi, Y; Hirata, KI; Inoue, N; Itoh, H; Kawashima, S; Ohashi, Y; Ozaki, M; Rikitake, Y; Yamashita, T; Yokoyama, M | 1 |
| Li, G; Liang, Y; Lu, J | 1 |
| Albertini, M; Ciminaghi, B; Clement, MG; Mazzola, S | 1 |
| Deuchar, GA; Docherty, A; Hicks, MN; MacLean, MR | 1 |
| Jinyong, W; Ruiping, X; Weidong, S; Xiaolong, W | 1 |
1 review(s) available for ng-nitroarginine methyl ester and Pulmonary Hypertension
| Article | Year |
|---|---|
Endothelium-derived nitric oxide and vascular physiology and pathology.
Topics: Animals; Arginine; Arteriosclerosis; Blood Vessels; Caveolin 1; Caveolins; Cell Adhesion; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Humans; Hypertension; Hypertension, Pulmonary; Isoenzymes; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxidative Stress; Rabbits; Signal Transduction; Vascular Diseases; Vasodilation | 1999 |
2 trial(s) available for ng-nitroarginine methyl ester and Pulmonary Hypertension
| Article | Year |
|---|---|
Pulmonary hypertension triggered by lipopolysaccharide in ascites-susceptible and -resistant broilers is not amplified by aminoguanidine, a specific inhibitor of inducible nitric oxide synthase.
Topics: Animals; Ascites; Chickens; Disease Susceptibility; Enzyme Inhibitors; Guanidines; Hypertension, Pulmonary; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Poultry Diseases | 2006 |
Pulmonary arterial pressure and electrocardiograms in broiler chickens infused intravenously with L-NAME, an inhibitor of nitric oxide synthase, or sodium nitroprusside (SNP), a nitric oxide donor.
Topics: Animals; Chickens; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; Hypertension, Pulmonary; Injections, Intravenous; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Pulmonary Wedge Pressure; Vascular Resistance; Vasoconstriction | 2002 |
83 other study(ies) available for ng-nitroarginine methyl ester and Pulmonary Hypertension
| Article | Year |
|---|---|
Saluisn-β contributes to endothelial dysfunction in monocrotaline-induced pulmonary arterial hypertensive rats.
Topics: Acetylcholine; Animals; Antioxidants; Disease Models, Animal; Hypertension; Hypertension, Pulmonary; Immunoglobulin G; Monocrotaline; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2022 |
Angiotensin-converting enzyme 2 activation ameliorates pulmonary endothelial dysfunction in rats with pulmonary arterial hypertension through mediating phosphorylation of endothelial nitric oxide synthase.
Topics: Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Endothelium, Vascular; Enzyme Activators; Humans; Hypertension, Pulmonary; Imidazoles; Leucine; Lung; Male; Monocrotaline; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Phosphorylation; Pulmonary Artery; Pyrans; Rats; Rats, Sprague-Dawley; Signal Transduction; Specific Pathogen-Free Organisms; Spiro Compounds; Xanthenes | 2017 |
Inhibition of nitric oxide synthase unmasks vigorous vasoconstriction in established pulmonary arterial hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Cyclic GMP; Hypertension, Pulmonary; Indoles; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase Inhibitors; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; Vasoconstriction | 2017 |
Eulophia macrobulbon extract relaxes rat isolated pulmonary artery and protects against monocrotaline-induced pulmonary arterial hypertension.
Topics: Animals; Calcium; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Orchidaceae; Plant Extracts; Plant Tubers; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Thailand; Vasodilation | 2018 |
Hypoxia augments NaHS-induced ANP secretion via KATP channel, HIF-1α and PPAR-γ pathway.
Topics: 2-Methoxyestradiol; Anilides; Animals; Atrial Natriuretic Factor; Bosentan; Gene Expression Regulation; Glyburide; Heart Atria; Hydrogen Sulfide; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; KATP Channels; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Organ Culture Techniques; Oxygen; Pinacidil; Potassium Channel Blockers; PPAR gamma; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfides | 2019 |
Total ginsenosides inhibit the right ventricular hypertrophy induced by monocrotaline in rats.
Topics: Animals; Blood Pressure; Blotting, Western; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ginsenosides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Mitogen-Activated Protein Kinases; Monocrotaline; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Panax; Poisons; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction | 2008 |
Cirrhosis ameliorates monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Common Bile Duct; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Hypertension, Pulmonary; Ligation; Liver Cirrhosis, Biliary; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasodilation | 2009 |
Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Bone Morphogenetic Protein Receptors, Type II; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Endothelial Cells; Gene Transfer Techniques; Genetic Therapy; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-10; Interleukin-6; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Survival Analysis; Tissue Extracts; Transforming Growth Factor beta | 2010 |
[Hypoxic pulmonary hypertension: the role of phosphatidylcholine-specific phospholipase C].
Topics: Animals; Blood Pressure; Enzyme Inhibitors; Hypertension, Pulmonary; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Protein Kinase C; Rats; Reactive Oxygen Species; Type C Phospholipases; Vasoconstriction; Ventricular Function, Left | 2009 |
Prostacyclin and milrinone by aerosolization improve pulmonary hemodynamics in newborn lambs with experimental pulmonary hypertension.
Topics: Administration, Inhalation; Aerosols; Animals; Animals, Newborn; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epoprostenol; Hemodynamics; Hypertension, Pulmonary; Indomethacin; Milrinone; NG-Nitroarginine Methyl Ester; Phosphodiesterase Inhibitors; Pulmonary Circulation; Sheep; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Angiography; Animals; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Lung; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Rats, Sprague-Dawley; Regional Blood Flow; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasodilator Agents | 2011 |
Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzoates; Biphenyl Compounds; Guanylate Cyclase; Heme; Hydrocarbons, Fluorinated; Hypertension, Pulmonary; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2011 |
The impact of L-NAME and L-arginine chronic toxicity induced lesions on ascites--pulmonary hypertension syndrome development in broiler chickens.
Topics: Animals; Arginine; Ascites; Chickens; Hemorrhage; Hypertension, Pulmonary; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Poultry Diseases; Toxicity Tests, Chronic | 2011 |
Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.
Topics: Animals; Antihypertensive Agents; Apoptosis; Blotting, Western; Caspase 3; Cells, Cultured; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Inhibitors; Familial Primary Pulmonary Hypertension; Glyburide; Human Umbilical Vein Endothelial Cells; Humans; Hypertension, Pulmonary; Injections, Intraperitoneal; Male; MAP Kinase Signaling System; Monocrotaline; NG-Nitroarginine Methyl Ester; Nicorandil; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventricular Pressure | 2012 |
The Rho kinase inhibitor azaindole-1 has long-acting vasodilator activity in the pulmonary vascular bed of the intact chest rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protein Kinase Inhibitors; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Vasodilator Agents | 2012 |
Ambrisentan reduces pulmonary arterial hypertension but does not stimulate alveolar and vascular development in neonatal rats with hyperoxic lung injury.
Topics: Animals; Animals, Newborn; Familial Primary Pulmonary Hypertension; Heart; Hyperoxia; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; NG-Nitroarginine Methyl Ester; Phenylpropionates; Pulmonary Alveoli; Pyridazines; Rats; Time Factors | 2013 |
Effect of L-NAME on pulmonary arterial pressure, plasma nitric oxide and pulmonary hypertension syndrome morbidity in broilers.
Topics: Animals; Blood Pressure; Chickens; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Hypertension, Pulmonary; Incidence; Injections, Intravenous; Morbidity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Poultry Diseases; Pulmonary Artery; Random Allocation; Syndrome; Vascular Resistance; Vasodilation | 2002 |
Endothelin-A receptor blockade in porcine pulmonary hypertension.
Topics: Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; NG-Nitroarginine Methyl Ester; Oligopeptides; Oxygen; Pulmonary Circulation; Receptor, Endothelin A; Streptococcal Infections; Streptococcus agalactiae; Sus scrofa; Thiazoles | 2002 |
Decreased association of HSP90 impairs endothelial nitric oxide synthase in fetal lambs with persistent pulmonary hypertension.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Adenosine Triphosphate; Animals; Blood Gas Analysis; Cell Separation; Cells, Cultured; Enzyme Inhibitors; Female; Fetus; HSP90 Heat-Shock Proteins; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Indicators and Reagents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pregnancy; Pulmonary Artery; Sheep; Vascular Resistance | 2003 |
Endogenous NO does not regulate baseline pulmonary pressure, but reduces acute pulmonary hypertension in dogs.
Topics: Acute Disease; Animals; Arginine; Blood Pressure; Dogs; Enzyme Inhibitors; Female; Hypertension, Pulmonary; Hypoxia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Alveoli | 2003 |
Augmented pulmonary vascular and venous constrictions to N(G)-nitro-L-arginine methyl ester in rats with monocrotaline-induced pulmonary hypertension.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction | 2003 |
[Interaction between endogenous nitric oxide and hydrogen sulfide in pathogenesis of hypoxic pulmonary hypertension].
Topics: Animals; Hydrogen Sulfide; Hypertension, Pulmonary; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Pulmonary Artery; Rats; Rats, Wistar | 2004 |
N(omega)-nitro-L-arginine methyl ester (L-NAME) amplifies the pulmonary hypertensive response to endotoxin in broilers.
Topics: Animals; Chickens; Drug Interactions; Enzyme Inhibitors; Escherichia coli; Gene Expression; Hypertension, Pulmonary; Lipopolysaccharides; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poultry Diseases; Salmonella typhimurium; Vascular Resistance; Vasoconstriction | 2004 |
JTV-506, a new K(ATP) channel opener, relaxes pulmonary artery isolated from monocrotaline-treated pulmonary hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Chromans; Hypertension, Pulmonary; In Vitro Techniques; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Pulmonary Artery; Rats; Rats, Wistar; Vasodilation | 2004 |
Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Blood Pressure; Calcium-Binding Proteins; Carbon Dioxide; Carbon Monoxide; Cyclic GMP; Drug Evaluation, Preclinical; Drug Interactions; Guanylate Cyclase-Activating Proteins; Hypertension, Pulmonary; Infusions, Intravenous; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen; Pulmonary Artery; Pyrazoles; Pyridines; Sheep; Vascular Resistance; Vasodilator Agents; Wakefulness | 2004 |
The role of 5-hydroxytryptamine in the control of pulmonary vascular tone in a rabbit model of pulmonary hypertension secondary to left ventricular dysfunction.
Topics: Animals; Aorta; Blood Pressure; Cardiac Output; Disease Models, Animal; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Ketanserin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Organ Size; Pulmonary Artery; Rabbits; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Antagonists; Stroke Volume; Ventricular Dysfunction, Left | 2005 |
l-Arginine attenuates acute pulmonary embolism-induced oxidative stress and pulmonary hypertension.
Topics: Acute Disease; Animals; Arginine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pulmonary Artery; Pulmonary Embolism; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2005 |
Analysis of pulmonary vascular response to acute alveolar hypoxic challenge in young rabbits subjected to chronic hypoxia from birth.
Topics: Animals; Blood Pressure; Blotting, Western; Enzyme Inhibitors; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pulmonary Artery; Rabbits; Time Factors | 2005 |
Macro- and micropulmonary hemodynamic changes to nitric oxide blockade in monocrotaline-induced pulmonary hypertension in rats--an in vivo approach.
Topics: Animals; Enzyme Inhibitors; Hypertension, Pulmonary; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction | 2005 |
Nomega-nitro-L-arginine methyl ester (L-NAME) amplifies the pulmonary hypertensive response to microparticle injections in broilers.
Topics: Animals; Cardiac Output; Chickens; Enzyme Inhibitors; Hypertension, Pulmonary; Male; Microspheres; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Poultry Diseases; Vasoconstriction | 2005 |
Pulmonary vascular iNOS induction participates in the onset of chronic hypoxic pulmonary hypertension.
Topics: Administration, Oral; Animals; Chronic Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exhalation; Hypertension, Pulmonary; Hypoxia; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pulmonary Artery; Rats; Rats, Wistar; Time Factors; Tyrosine | 2006 |
L-Arginine prevents air embolism-induced acute lung injury in rats.
Topics: Acute Disease; Animals; Arginine; Bronchoalveolar Lavage; Capillary Permeability; Disease Models, Animal; Embolism, Air; Hypertension, Pulmonary; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Organ Size; Proteins; Pulmonary Edema; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Selective right, but not left, coronary endothelial dysfunction precedes development of pulmonary hypertension and right heart hypertrophy in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Exogenous nitric oxide centrally enhances pulmonary reactivity in the normal and hypertensive rat.
Topics: Animals; Blood Pressure; Cardiac Output; Central Nervous System; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Injections, Intraventricular; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance; Vasoconstriction | 2005 |
Contribution of pulmonary surfactant with inhaled nitric oxide for treatment of pulmonary hypertension.
Topics: Administration, Inhalation; Animals; Animals, Newborn; Drug Therapy, Combination; Hypertension, Pulmonary; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Surfactants; Respiratory Function Tests; Swine; Vasodilator Agents | 2006 |
Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats.
Topics: Acetylcholine; Animals; Biological Factors; Catalase; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Microcirculation; Microscopy, Video; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2007 |
Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antihypertensive Agents; Carbolines; Cardiomyopathies; Cardiovascular Agents; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Doxorubicin; Endothelium, Vascular; Enzyme Inhibitors; Erectile Dysfunction; Heart Failure; Humans; Hypertension; Hypertension, Pulmonary; Imidazoles; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents; Ventricular Remodeling | 2007 |
Reduced pulmonary vascular reactivity after cold exposure to acute hypoxia: a role of nitric oxide (NO).
Topics: Animals; Body Temperature Regulation; Cold Temperature; Hypertension, Pulmonary; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Rats; Rats, Wistar | 2007 |
beta-adrenergic relaxation in pulmonary arteries: preservation of the endothelial nitric oxide-dependent beta2 component in pulmonary hypertension.
Topics: Animals; Chronic Disease; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Reactive Oxygen Species; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-2; Vasodilation | 2008 |
Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice.
Topics: Animals; Blood Pressure; Caveolin 1; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Liver; Lung; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Oxidants; Oxidative Stress; Phenotype; Physical Conditioning, Animal; Pulmonary Artery; Respiratory Function Tests; Signal Transduction; Superoxides | 2008 |
Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Perfusion; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasodilation | 1993 |
Attenuation of chronic hypoxic pulmonary hypertension in rats by cyclooxygenase products and by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Arginine; Blood Pressure; Dilatation; Dinoprost; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Rats; Rats, Wistar | 1993 |
Effect of nitric oxide synthase inhibition during group B streptococcal sepsis in neonatal piglets.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Hemodynamics; Hypertension, Pulmonary; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Gas Exchange; Sepsis; Streptococcal Infections; Streptococcus agalactiae; Swine | 1994 |
Evidence that nitric oxide from the endothelium attenuates inherent tone in isolated pulmonary arteries from rats with hypoxic pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Dose-Response Relationship, Drug; Endothelium; Hypertension, Pulmonary; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Pulmonary Artery; Rats; Rats, Wistar | 1995 |
Inhaled nitric oxide does not alter the longitudinal distribution of pulmonary vascular resistance.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Endoperoxides, Synthetic; Pulmonary Wedge Pressure; Rabbits; Respiration, Artificial; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents | 1995 |
[Effect of NG-nitro-L-arginine methylester on the secretion of endothelin-1 in vivo and in cultured endothelial cells].
Topics: Animals; Arginine; Cells, Cultured; Dogs; Endothelins; Endothelium, Vascular; Female; Humans; Hypertension, Pulmonary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Umbilical Veins | 1995 |
[Inhibition of endogenous nitric oxide synthesis enhances acute hypoxic pulmonary vasoconstriction].
Topics: Animals; Arginine; Blood Pressure; Dogs; Hypertension, Pulmonary; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Vascular Resistance; Vasoconstriction | 1994 |
The pulmonary effect of nitric oxide synthase inhibition following endotoxemia in a swine model.
Topics: Administration, Inhalation; Animals; Arginine; Bacteremia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli Infections; Female; Hypertension, Pulmonary; Hypoxia; Lung Volume Measurements; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Edema; Pulmonary Wedge Pressure; Random Allocation; Swine | 1994 |
Effect of l-glutamine on pulmonary hypertension in the perfused rabbit lung.
Topics: Animals; Arginine; Blood Pressure; Glutamine; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Pulmonary Artery; Rabbits | 1994 |
Endogenous nitric oxide and pulmonary vascular tone in the neonate.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Extracorporeal Membrane Oxygenation; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Respiratory Mechanics; Swine; Vascular Resistance | 1996 |
Effects of pulmonary hypertension on vasoconstrictor responses to endothelin-1 and sarafotoxin S6C and on inherent tone in rat pulmonary arteries.
Topics: Animals; Arginine; Endothelins; Endothelium, Vascular; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Pulmonary Artery; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 1995 |
Cardiopulmonary effects of combined nitric oxide inhibition and inhaled nitric oxide in porcine endotoxic shock.
Topics: Administration, Inhalation; Animals; Endotoxemia; Enzyme Inhibitors; Female; Heart; Hemodynamics; Hypertension, Pulmonary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Respiration; Shock, Septic; Swine | 1996 |
Inhibition of endogenous nitric oxide synthase potentiates nitrovasodilators in experimental pulmonary hypertension.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alprostadil; Animals; Drug Synergism; Enzyme Inhibitors; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Perfusion; Pulmonary Circulation; Rabbits; Vasodilator Agents | 1996 |
Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
Topics: Aminorex; Animals; Appetite Depressants; Enzyme Inhibitors; Fenfluramine; Hypertension, Pulmonary; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Patch-Clamp Techniques; Potassium Channel Blockers; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1996 |
Decreased pulmonary arterial endothelium-dependent relaxation in heartworm-infected dogs with pulmonary hypertension.
Topics: Animals; Blood Pressure; Carbachol; Dirofilariasis; Dog Diseases; Dogs; Endothelium, Vascular; Female; Hypertension, Pulmonary; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Pulmonary Artery; Reference Values | 1997 |
Treatment with 5-HT potentiates development of pulmonary hypertension in chronically hypoxic rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Infusions, Intravenous; Lung; Male; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Thromboxane A2; Tropanes; Vasoconstriction; Vasodilation | 1997 |
Lack of haemodynamic effects of nitric oxide on post-capillary pulmonary hypertension induced by acute sino-aortic denervation.
Topics: Adrenergic beta-Antagonists; Animals; Denervation; Dogs; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Piperazines; Propranolol; Pulmonary Circulation; Sinoatrial Node; Vasodilator Agents | 1997 |
The role of endogenous nitric oxide in the sympathetic and hemodynamic response to platelet activating factor-induced hypotension in anesthetized dogs.
Topics: Anesthetics; Animals; Blood Gas Analysis; Blood Pressure; Dogs; Enzyme Inhibitors; Female; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypotension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Sympathetic Nervous System; Vasomotor System | 1998 |
Influence of applied tension and nitric oxide on responses to endothelins in rat pulmonary resistance arteries: effect of chronic hypoxia.
Topics: Animals; Endothelin-1; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Rats; Rats, Wistar; Vasodilator Agents; Viper Venoms | 1998 |
Effect of inhaled nitric oxide in endothelin-1-induced pulmonary hypertension.
Topics: Administration, Inhalation; Animals; Drug Interactions; Endothelin-1; Enzyme Inhibitors; Female; Hypertension, Pulmonary; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Swine; Vascular Resistance | 1998 |
Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Calcitonin Gene-Related Peptide; Cardiac Catheterization; Enzyme Inhibitors; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitroglycerin; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vasomotor System | 1998 |
L-NAME does not affect exercise-induced pulmonary hypertension in thoroughbred horses.
Topics: Animals; Blood Pressure; Enzyme Inhibitors; Female; Heart Rate; Horses; Hypertension, Pulmonary; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Physical Exertion; Pulmonary Circulation; Pulmonary Wedge Pressure | 1998 |
Pulmonary hypertension and reduced cardiac output during inhibition of nitric oxide synthesis in human septic shock.
Topics: Aged; Cardiac Output; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension, Pulmonary; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pilot Projects; Shock, Septic | 1998 |
Garlic prevents hypoxic pulmonary hypertension in rats.
Topics: Acetylcholine; Animals; Blood Pressure; Endothelium, Vascular; Garlic; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Phytotherapy; Plant Extracts; Plants, Medicinal; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1998 |
Pulmonary hypertensive effects of lung inflation in chronic hypoxia: a study in rats.
Topics: Animals; Enzyme Inhibitors; Hypertension, Pulmonary; Hypoxia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Wistar; Vascular Resistance | 1998 |
Inhibition of endogenous nitric oxide synthesis potentiates the effects of sodium nitroprusside but not of adenosine in experimental pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Synergism; Hemodynamics; Hypertension, Pulmonary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rabbits; Vasodilator Agents | 1999 |
Intestinal and hepatic perfusion and metabolism in hypodynamic endotoxic shock. Effects of nitric oxide synthase inhibition.
Topics: Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia coli; Female; Hemodynamics; Hepatic Artery; Hypertension, Pulmonary; Intestine, Small; Lactates; Lipopolysaccharides; Liver; Lung; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Portal Vein; Regional Blood Flow; Shock, Septic; Survival Rate; Swine; Vascular Resistance; Vasoconstrictor Agents; Ventricular Function, Left | 1999 |
Heparin and protamine interaction.
Topics: Animals; Anticoagulants; Drug Interactions; Enzyme Inhibitors; Hemodynamics; Heparin; Heparin Antagonists; Hypertension, Pulmonary; Hypotension; Lung; Myocardial Contraction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protamines; Rats; Reperfusion Injury | 1998 |
Pulmonary artery endothelium-dependent vasodilation is impaired in a chicken model of pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Chickens; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Ionophores; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Papaverine; Pulmonary Artery; Vasodilation; Vasodilator Agents | 1999 |
Hemodynamic effects of basal and stimulated release of endogenous nitric oxide in isolated human lungs.
Topics: Acetylcholine; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension, Pulmonary; In Vitro Techniques; Lung; Lung Diseases, Obstructive; NG-Nitroarginine Methyl Ester; Nitric Oxide; Vasodilator Agents | 1999 |
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Inhalation; Animals; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Epoprostenol; Hypertension, Pulmonary; Hypoxia; Lung; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Poisons; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1999 |
Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs.
Topics: Aerosols; Animals; Enzyme Inhibitors; Female; Fetus; Hypertension, Pulmonary; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen; Polyamines; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Sheep; Vasodilation | 1999 |
In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse.
Topics: Adenoviridae; Adrenomedullin; Animals; beta-Galactosidase; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Endothelin-1; Genes, Reporter; Genetic Therapy; Genetic Vectors; Hemodynamics; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Mice; NG-Nitroarginine Methyl Ester; Peptides; Phosphodiesterase Inhibitors; Potassium Channels; Protein Precursors; Purinones; Recombinant Fusion Proteins; Rolipram; Second Messenger Systems; Transfection; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Contractile responses to human urotensin-II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Growth Factors; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypertension, Pulmonary; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen; Pulmonary Artery; Rats; Rats, Wistar; Urotensins; Vasoconstriction | 2000 |
Sildenafil is a pulmonary vasodilator in awake lambs with acute pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Acute Disease; Animals; Blood Pressure; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Enzyme Inhibitors; Hypertension, Pulmonary; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Pulmonary Artery; Pulmonary Circulation; Purines; Purinones; Sheep; Sildenafil Citrate; Sulfones; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Wakefulness | 2000 |
Analysis of responses of garlic derivatives in the pulmonary vascular bed of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adamantane; Allyl Compounds; Animals; Antihypertensive Agents; Antioxidants; Bronchodilator Agents; Cromakalim; Cyclooxygenase Inhibitors; Disulfides; Diuretics; Enzyme Inhibitors; Garlic; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Meclofenamic Acid; Morpholines; NG-Nitroarginine Methyl Ester; Plants, Medicinal; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Respiration; Sulfhydryl Compounds; Sulfinic Acids; Vasoconstrictor Agents | 2000 |
Combination therapy with inhaled nitric oxide and intravenous dobutamine during pulmonary hypertension in the rabbit.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Animals; Blood Pressure; Cardiac Output; Dobutamine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Hypertension, Pulmonary; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Circulation; Rabbits; Vascular Resistance; Vasodilation | 2000 |
Garlic elicits a nitric oxide-dependent relaxation and inhibits hypoxic pulmonary vasoconstriction in rats.
Topics: Acetylcholine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Garlic; Hypertension, Pulmonary; Hypoxia; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phytotherapy; Plant Extracts; Plants, Medicinal; Pulmonary Artery; Rats; Vasodilation | 2000 |
The NO donor molsidomine reduces endothelin-1 gene expression in chronic hypoxic rat lungs.
Topics: Animals; Chronic Disease; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Glyceraldehyde-3-Phosphate Dehydrogenases; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger; Vasodilator Agents | 2001 |
Reduced hypoxic pulmonary vascular remodeling by nitric oxide from the endothelium.
Topics: Animals; Blood Pressure; Blood Vessels; Cyclic GMP; Endothelin-1; Female; Genotype; Heart Rate; Hematocrit; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Immunoblotting; Lung; Male; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ventricular Function, Right; Ventricular Pressure | 2001 |
[Changes of nitric oxide synthase in hypoxic pulmonary hypertension and the effect of L-arg and L-NAME on pulmonary circulation].
Topics: Animals; Arginine; Endothelium, Vascular; Female; Hypertension, Pulmonary; Hypoxia; Lung; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Circulation; Random Allocation; Rats; Rats, Wistar | 1998 |
Improvement of respiratory function by bosentan during endotoxic shock in the pig.
Topics: Animals; Antihypertensive Agents; Bosentan; Enzyme Inhibitors; Female; Hypertension, Pulmonary; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Edema; Respiration; Shock, Septic; Sulfonamides; Swine; Time Factors | 2001 |
Pulmonary hypertension secondary to left ventricular dysfunction: the role of nitric oxide and endothelin-1 in the control of pulmonary vascular tone.
Topics: Animals; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Indans; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Precursors; Pulmonary Artery; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Ultrasonography; Ventricular Dysfunction, Left | 2002 |