ng-nitroarginine methyl ester has been researched along with Obesity in 58 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (10.34) | 18.2507 |
| 2000's | 30 (51.72) | 29.6817 |
| 2010's | 20 (34.48) | 24.3611 |
| 2020's | 2 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno, RM; Cappelli, F; Duranti, E; Mengozzi, A; Moriconi, D; Nannipieri, M; Taddei, S; Virdis, A | 1 |
| Gillette, TG; Hill, JA; Jiang, N; Lavandero, S; May, HI; Schiattarella, GG; Tong, D | 1 |
| Aalkjaer, C; Chen, H; Simonsen, U | 1 |
| Ahmed, MM; Kamar, SS; Mahmoud, MM; Rashed, L; Sabry, MM; Shoukry, HS | 1 |
| Prendergast, C; Wray, S | 1 |
| Cameli, M; Donnini, S; Focardi, M; Marzilli, M; Mondillo, S; Picchi, A; Ziche, M | 1 |
| Filgueira, FP; Lobato, NS; Lopes, RA; Neves, KB; Oliveira, AM; Tostes, RC; Zanotto, CZ | 1 |
| Bendhack, LM; Cecchini, R; da Cunha, NV; Grando, MD; Martins-Pinge, MC; Panis, C; Pernomian, L; Pinge-Filho, P; Silva, BR | 1 |
| Akamine, EH; Aragão, DS; Carvalho, MH; Casarini, DE; Filgueira, FP; Fortes, ZB; Hagihara, GN; Lobato, NS | 1 |
| Barron, FE; Burridge, PW; Churko, JM; Diecke, S; Gold, JD; Gu, M; He, C; Hu, S; Kooreman, NG; Lee, J; Mordwinkin, NM; Ong, SG; Wu, H; Wu, JC | 1 |
| Jenkins, NT; Laughlin, MH; Padilla, J; Rector, RS; Sheldon, RD | 1 |
| Balfagón, G; Blanco-Rivero, J; Caracuel, L; Sastre, E | 1 |
| Bidani, AK; Bisla, R; Griffin, KA; Licea-Vargas, H; Long, J; Picken, M; Polichnowski, AJ; Williamson, GA | 1 |
| Babana, JC; Bian, JT; Franklin, NC; Norkeviciute, E; Phillips, SA; Robinson, AT; Szczurek, MR | 1 |
| Ha, H; Huh, JY; Jung, I; Miyata, T; Piao, L | 1 |
| Frisbee, JC; Goodwill, AG; James, ME | 1 |
| Ceylan-Isik, AF; Esberg, LB; Relling, DP; Ren, J; Zhu, BH | 1 |
| Busija, AR; Busija, DW; Domoki, F; Jarajapu, YP; Katakam, PV; Snipes, JA | 1 |
| Alvarez de Sotomayor, M; Callejón Mochón, M; Casto, C; Herrera, MD; Jiménez-Palacios, FJ; Marhuenda, E; Mingorance, C | 1 |
| Aillaud, M; Asagami, T; Azuma, J; Deng, AC; Jin, H; Kundu, RK; Quertermous, T; Reaven, GM; Tsao, PS; Yue, P | 1 |
| Belin de Chantemèle, EJ; Guihot, AL; Henrion, D; Loufrani, L; Toutain, B; Vessières, E | 1 |
| Aburada, M; Hemmi, C; Iizuka, S; Ito, M; Kawada, T; Mihara, K; Miyata, S; Nakazawa, M; Sanzen, Y; Shimada, T; Suzuki, W | 1 |
| Chang, WC; Chen, JS; Jao, CC; Lee, SD; Shyu, WC; Wang, HJ; Wu, BT | 1 |
| Ambrozewicz, MA; Baydoun, HA; DeBose, SC; Dobrian, AD; Khraibi, AA; Simsek-Duran, F | 1 |
| Baptista, Rde F; Campos, DH; Cicogna, AC; Cordellini, S; Leopoldo, AP; Leopoldo, AS; Nascimento, TB; Oliveira Júnior, SA; Padovani, CR; Pereira, PC | 1 |
| Anselmino, M; Bernardini, N; Blandizzi, C; Colucci, R; Duranti, E; Pinchera, A; Rugani, I; Salvetti, A; Salvetti, G; Santini, F; Segnani, C; Taddei, S; Virdis, A | 1 |
| Barton, M; D'Uscio, LV; Morawietz, H; Muenter, K; Traupe, T; Vetter, W | 1 |
| Darby, I; Karagiannis, J; Li, CG; Rand, MJ; Reid, JJ; Roche, P | 1 |
| Kelly, SE; Russell, JC; Schäfer, S | 1 |
| Sadler, CJ; Wilding, JP | 1 |
| Busija, DW; Erdös, B; Katakam, PV; Miller, AW; Snipes, JA; Tulbert, CD | 1 |
| Frisbee, JC | 1 |
| Fujita, K; Funahashi, T; Hibuse, T; Hiuge, A; Kihara, S; Kumada, M; Maeda, K; Maeda, N; Nishizawa, H; Ohashi, K; Ouchi, N; Ryo, M; Shibata, R; Shimomura, I; Walsh, K | 1 |
| Chao, JI; Lee, SD; Yang, AL | 1 |
| Hutchings, SR; Pang, CC; Song, D | 1 |
| Hussain, T; Siddiqui, AH | 1 |
| Barton, M; Bhattacharya, I; Haas, E; Hofmann-Lehmann, R; Kretz, M; Minotti, R; Mundy, AL; Widmer, CC | 1 |
| Adams, F; Boschmann, M; Engeli, S; Franke, G; Gorzelniak, K; Janke, J; Jordan, J; Luft, FC | 1 |
| Abello, V; Carpéné, C; Prévot, D; Soltesz, Z; Unzeta, M; Valet, P; Wanecq, E | 1 |
| Hirata, Y; Iwashima, F; Sakai, H; Shichiri, M; Suzuki, N; Tsuchiya, K; Yoshimoto, T | 1 |
| Bender, SB; Klabunde, RE | 1 |
| Desouza, CA; Greiner, JJ; Stauffer, BL; Van Guilder, GP | 1 |
| Bagi, Z; Edes, I; Erdei, N; Feher, A; Forster, T; Jebelovszki, E; Kiraly, C; Koller, A; Pasztor, ET; Rutkai, I | 1 |
| Beck, B; Burlet, C; Stricker-Krongrad, A | 1 |
| Brunner, HR; Delacrétaz, E; Gaillard, R; Jeanrenaud, B; Taleb, V; Waeber, B; Zanchi, A | 1 |
| Dubé, GP; McKendrick, JD; Murat, J; Radomski, MW; Russell, JC; Salas, E | 1 |
| Davidge, ST; O'Brien, SF; Russell, JC | 2 |
| Arvola, P; Kähönen, M; Kainulainen, H; Mäkynen, H; Mucha, I; Pörsti, I; Riutta, A; Solakivi, T; Wu, X | 1 |
| Anggård, EE; Carrier, MJ; Desai, KM; Laight, DW | 1 |
| Davidge, ST; Dolphin, PJ; O'Brien, SF; Russell, JC | 1 |
| Doyle, PJ; Naderali, EK; Smith, SL; Williams, G | 1 |
| Arbin, V; Claperon, N; Fournié-Zaluski, MC; Peyroux, J; Roques, BP | 1 |
| Johns, EJ; Wongmekiat, O | 1 |
| Frühbeck, G; Gómez-Ambrosi, J | 1 |
| Frisbee, JC; Stepp, DW | 1 |
| Anggård, EE; Carrier, MJ; Laight, DW | 1 |
| Ishimura, N; Nakaya, Y; Takahashi, A; Takishita, E | 1 |
2 trial(s) available for ng-nitroarginine methyl ester and Obesity
| Article | Year |
|---|---|
Dissociation between adipose nitric oxide synthase expression and tissue metabolism.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Body Weight; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycerol; Humans; Isoproterenol; Lipolysis; Male; Microdialysis; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Obesity; Prospective Studies | 2007 |
Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists.
Topics: Acetylcholine; Adult; Aged; Body Mass Index; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intravenous; Isoproterenol; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Obesity; Regional Blood Flow; Signal Transduction; Substance P; Vasodilation; Vasodilator Agents | 2008 |
56 other study(ies) available for ng-nitroarginine methyl ester and Obesity
| Article | Year |
|---|---|
The renal resistive index is associated with microvascular remodeling in patients with severe obesity.
Topics: Albuminuria; Humans; Hypertension; Kidney; Microcirculation; NG-Nitroarginine Methyl Ester; Obesity; Obesity, Morbid; Vascular Resistance | 2023 |
Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction.
Topics: Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose Intolerance; Heart Failure; Humans; Hypertension; Male; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Risk Factors; Sex Characteristics; Sex Factors; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling; Weight Gain | 2019 |
A sex-specific, COX-derived/thromboxane receptor activator causes depolarization and vasoconstriction in male mice mesenteric resistance arteries.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Mice; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Obesity; Piperazines; Receptors, Thromboxane; Sex Characteristics; Thiazoles; Vascular Resistance; Vasoconstriction; Vasodilation | 2020 |
Interactive effects of apelin, renin-angiotensin system and nitric oxide in treatment of obesity-induced type 2 diabetes mellitus in male albino rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apelin; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Therapy, Combination; Enzyme Inhibitors; Insulin; Insulin Resistance; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Obesity; Rats; Renin-Angiotensin System | 2019 |
Human myometrial artery function and endothelial cell calcium signalling are reduced by obesity: Can this contribute to poor labour outcomes?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arginine Vasopressin; Arteries; beta-Cyclodextrins; Bradykinin; Calcium Signaling; Carbachol; Endothelial Cells; Female; Humans; Myometrium; NG-Nitroarginine Methyl Ester; Obesity; Obstetric Labor Complications; Pregnancy; S-Nitroso-N-Acetylpenicillamine; Uterine Contraction | 2019 |
Hydrogen peroxide mediates endothelium-dependent dilation of coronary arterioles in obese rats on a low-carbohydrate diet.
Topics: Acetylcholine; Animals; Arterioles; Coronary Circulation; Dietary Carbohydrates; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Obesity; Rats; Rats, Zucker; Vasodilation; Vasodilator Agents | 2013 |
Chemerin reduces vascular nitric oxide/cGMP signalling in rat aorta: a link to vascular dysfunction in obesity?
Topics: Acetylcholine; Adipokines; Animals; Aorta, Thoracic; Cyclic GMP; Endothelium, Vascular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Rats; Rats, Wistar; Signal Transduction; Superoxide Dismutase; Superoxides | 2014 |
Decreased endothelial nitric oxide, systemic oxidative stress, and increased sympathetic modulation contribute to hypertension in obese rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium Glutamate; Sympathetic Nervous System | 2014 |
Upregulation of ERK1/2-eNOS via AT2 receptors decreases the contractile response to angiotensin II in resistance mesenteric arteries from obese rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Phosphorylation; Pyridines; Rats, Wistar; Receptor, Angiotensin, Type 2; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents | 2014 |
Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.
Topics: Analysis of Variance; Animals; Apoptosis; Cell Differentiation; Diet, High-Fat; Endothelial Cells; Enzyme Inhibitors; Fibroblasts; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Induced Pluripotent Stem Cells; Injections, Intramuscular; Ischemia; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Oxidative Stress; Pravastatin; Proto-Oncogene Proteins c-akt; Random Allocation; Reperfusion Injury; Signal Transduction | 2015 |
Chronic NOS inhibition accelerates NAFLD progression in an obese rat model.
Topics: Adaptation, Physiological; Animals; Chemical and Drug Induced Liver Injury; Disease Progression; Eating; Enzyme Inhibitors; Inflammation Mediators; Insulin Resistance; Lipids; Liver; Liver Cirrhosis, Experimental; Macrophages; Mitochondria, Liver; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Non-alcoholic Fatty Liver Disease; Obesity; Rats, Inbred OLETF; Time Factors | 2015 |
Aerobic exercise training increases nitrergic innervation function and decreases sympathetic innervation function in mesenteric artery from rats fed a high-fat diet.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Diet, High-Fat; Electric Stimulation; Enzyme Inhibitors; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Norepinephrine; Obesity; Phentolamine; Physical Conditioning, Animal; Rats; Rats, Wistar; Suramin; Sympathetic Nervous System; Vasoconstriction | 2015 |
Glomerulosclerosis in the diet-induced obesity model correlates with sensitivity to nitric oxide inhibition but not glomerular hyperfiltration or hypertrophy.
Topics: Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glomerular Filtration Rate; Glomerulonephritis; Hemodynamics; Hypertension; Hypertrophy; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Proteinuria; Rats, Sprague-Dawley; Renal Circulation; Time Factors; Vascular Resistance | 2015 |
Improved arterial flow-mediated dilation after exertion involves hydrogen peroxide in overweight and obese adults following aerobic exercise training.
Topics: Adult; Brachial Artery; Catalase; Exercise; Female; Humans; Hydrogen Peroxide; Male; Microvessels; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Physical Conditioning, Human; Physical Exertion; Rest; Sedentary Behavior; Vasodilation; Young Adult | 2016 |
A novel plasminogen activator inhibitor-1 inhibitor, TM5441, protects against high-fat diet-induced obesity and adipocyte injury in mice.
Topics: Adipocytes; Animals; Diet, High-Fat; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Obesity; para-Aminobenzoates; Piperazines; Serpin E2; Structure-Activity Relationship | 2016 |
Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension.
Topics: Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; Fatty Acids, Unsaturated; Free Radical Scavengers; Hydrazines; Hypoxia; Imidazoles; Indomethacin; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Zucker; Receptors, Thromboxane; Superoxide Dismutase; Thromboxane A2; Thromboxane-A Synthase; Up-Regulation; Vasodilation | 2008 |
High-fat diet-induced obesity leads to resistance to leptin-induced cardiomyocyte contractile response.
Topics: Animals; Calcium; Cells, Cultured; Diet, Fat-Restricted; Dietary Fats; Enzyme Inhibitors; Imidazoles; Leptin; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Obesity; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Tyrphostins | 2008 |
Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance.
Topics: Animals; Cerebral Arteries; Cyclooxygenase Inhibitors; Diazoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Indomethacin; Insulin Resistance; Male; Metalloporphyrins; Mitochondria; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitro Compounds; Obesity; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Propionates; Rats; Rats, Zucker; Reactive Oxygen Species; Succinate Dehydrogenase; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 2009 |
Effects of chronic treatment with the CB1 antagonist, rimonabant on the blood pressure, and vascular reactivity of obese Zucker rats.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Rate; Indomethacin; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Obesity; Phenylephrine; Piperidines; Pyrazoles; Rats; Rats, Zucker; Receptor, Cannabinoid, CB1; Rimonabant; Vasoconstriction; Vasodilation | 2009 |
Apelin is necessary for the maintenance of insulin sensitivity.
Topics: Adipokines; AMP-Activated Protein Kinases; Animals; Apelin; Carrier Proteins; Cells, Cultured; Chromones; Deoxyglucose; Diabetes Mellitus, Type 2; Dietary Sucrose; Enzyme Inhibitors; Hyperinsulinism; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Muscle, Skeletal; Myoblasts; NG-Nitroarginine Methyl Ester; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Leptin; Signal Transduction; Tritium | 2010 |
Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries.
Topics: Acetylcholine; Age Factors; Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hypertrophy; Indomethacin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitrobenzenes; Obesity; Rats; Rats, Zucker; Regional Blood Flow; Splanchnic Circulation; Sulfonamides; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
A study of cardiovascular function in Tsumura Suzuki obese diabetes, a new model mouse of type 2 diabetes.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus, Type 2; Disease Models, Animal; Echocardiography; Endothelium, Vascular; Heart; Hyperglycemia; Hyperinsulinism; Hyperlipidemias; Kidney; Male; Mice; Mice, Inbred Strains; Mice, Obese; NG-Nitroarginine Methyl Ester; Obesity; Pancreas; Reference Values; Vasodilation | 2010 |
Altered nitroxidergic and NMDA receptor-mediated modulation of baroreflex-mediated heart rate in obese Zucker rats.
Topics: Animals; Baroreflex; Blood Pressure; Dextromethorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide; Obesity; Phenylephrine; Rats; Rats, Zucker; Receptors, N-Methyl-D-Aspartate; Sympathomimetics | 2010 |
Different natriuretic responses in obese and lean rats in response to nitric oxide reduction.
Topics: Animals; Blood Pressure; Diuresis; Hypertension; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Obesity; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 2011 |
Vascular alterations in high-fat diet-obese rats: role of endothelial L-arginine/NO pathway.
Topics: Adiposity; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; Body Weight; Diet, High-Fat; Endothelium, Vascular; Epinephrine; Male; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Obesity; Rats; Rats, Wistar; Time Factors | 2011 |
Vascular generation of tumor necrosis factor-α reduces nitric oxide availability in small arteries from visceral fat of obese patients.
Topics: Acetylcholine; Adult; Antibodies, Monoclonal; Arteries; Blotting, Western; Cyclic N-Oxides; Endothelium, Vascular; Female; Humans; Immunohistochemistry; In Vitro Techniques; Infliximab; Insulin Resistance; Intra-Abdominal Fat; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Obesity; Reactive Oxygen Species; Spin Labels; Superoxides; Tumor Necrosis Factor-alpha; Up-Regulation; Vasodilation; Vasodilator Agents | 2011 |
Effects of obesity on endothelium-dependent reactivity during acute nitric oxide synthase inhibition: modulatory role of endothelin.
Topics: Acetylcholine; Animals; Aorta; Carotid Arteries; Endothelin Receptor Antagonists; Endothelium, Vascular; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Phenylpropionates; Pyrimidines; Receptor, Endothelin A; Vasodilator Agents | 2002 |
Impaired nitric oxide function in the basilar artery of the obese Zucker rat.
Topics: Acetylcholine; Animals; Basilar Artery; Biogenic Amines; Calcimycin; Endothelium, Vascular; Female; Hemodynamics; Insulin Resistance; Metabolism; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Obesity; Papaverine; Rats; Rats, Zucker | 2003 |
Vasopeptidase inhibition improves insulin sensitivity and endothelial function in the JCR:LA-cp rat.
Topics: Acetylcholine; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Aorta, Thoracic; Blood Glucose; Body Weight; Bradykinin; Diet; Disease Models, Animal; Eating; Endothelium, Vascular; Fasting; Heart; Heart Rate; Heterocyclic Compounds, 3-Ring; Insulin; Insulin Resistance; Male; Muscle, Smooth, Vascular; Neprilysin; NG-Nitroarginine Methyl Ester; Nitroprusside; Obesity; Organ Size; Phenylephrine; Ramipril; Rats; Vasoconstriction; Vasodilation | 2004 |
Reduced ventromedial hypothalamic neuronal nitric oxide synthase and increased sensitivity to NOS inhibition in dietary obese rats: further evidence of a role for nitric oxide in the regulation of energy balance.
Topics: Analysis of Variance; Animals; Body Weight; Cell Count; Diet; Energy Intake; Enzyme Inhibitors; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Obesity; Rats; Rats, Wistar; Ventromedial Hypothalamic Nucleus | 2004 |
Impaired insulin-induced vasodilation in small coronary arteries of Zucker obese rats is mediated by reactive oxygen species.
Topics: Acetylcholine; Animals; Antioxidants; Coronary Vessels; Enzyme Inhibitors; Hypoglycemic Agents; Insulin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Obesity; Rats; Rats, Zucker; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2005 |
Reduced nitric oxide bioavailability contributes to skeletal muscle microvessel rarefaction in the metabolic syndrome.
Topics: Animals; Antioxidants; Biological Availability; Cyclic N-Oxides; Enzyme Inhibitors; Free Radical Scavengers; Hyperemia; Male; Metabolic Syndrome; Microcirculation; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Obesity; Oxidative Stress; Rats; Rats, Zucker; Regional Blood Flow; Spin Labels; Vasodilation | 2005 |
Adiponectin replenishment ameliorates obesity-related hypertension.
Topics: Adenoviridae; Adiponectin; Animals; Aorta; Blood Pressure; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Transfer Techniques; Genetic Vectors; Hypertension; Insulin Resistance; Intramolecular Oxidoreductases; Male; Mice; Mice, Inbred Strains; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Obesity; RNA, Messenger; Sodium Chloride, Dietary | 2006 |
Altered insulin-mediated and insulin-like growth factor-1-mediated vasorelaxation in aortas of obese Zucker rats.
Topics: Androstadienes; Animals; Aorta, Thoracic; Enzyme Inhibitors; Insulin; Insulin Antagonists; Insulin-Like Growth Factor I; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Obesity; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Zucker; Vasodilation; Vasodilator Agents; Wortmannin | 2007 |
Impaired in vivo venous constriction in conscious obese Zucker rats with metabolic syndrome.
Topics: Animals; Blood Glucose; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Insulin; Male; Metabolic Syndrome; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Norepinephrine; Obesity; Rats; Rats, Zucker; Regional Blood Flow; Triglycerides; Vasoconstriction; Vasoconstrictor Agents; Veins | 2006 |
Enhanced AT1 receptor-mediated vasocontractile response to ANG II in endothelium-denuded aorta of obese Zucker rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Body Weight; Endothelial Cells; Endothelin-1; Enzyme Inhibitors; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitroprusside; Obesity; Potassium Chloride; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesity.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blotting, Western; Cholesterol; Dietary Fats; Endothelin-1; Endothelium, Vascular; Gene Expression; Glucose Tolerance Test; Hydroxyl Radical; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Receptors, Angiotensin; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue, White; Adult; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Body Fat Distribution; Brain; Cells, Cultured; Enzyme Inhibitors; Female; Guanidines; Humans; Insulin; Liver; Mice; Monoamine Oxidase; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Obesity; Rats; Rats, Zucker; Semicarbazides; Tyramine | 2007 |
Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.
Topics: Adipose Tissue; Adiposity; Animals; Blood Pressure; Catecholamines; Dietary Fats; Drug Administration Schedule; Enzyme Inhibitors; Gene Expression; Glucose Tolerance Test; Inflammation; Insulin; Insulin Resistance; Isoenzymes; Male; Metabolism; Mice; Mice, Inbred C57BL; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Obesity; Organ Size; Proteins; Signal Transduction | 2007 |
Altered role of smooth muscle endothelin receptors in coronary endothelin-1 and alpha1-adrenoceptor-mediated vasoconstriction in Type 2 diabetes.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Oligopeptides; Peptides, Cyclic; Phenylephrine; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Adrenergic, alpha-1; Vasoconstriction | 2007 |
High-fat diet-induced obesity leads to increased NO sensitivity of rat coronary arterioles: role of soluble guanylate cyclase activation.
Topics: Acetylcholine; Adaptation, Physiological; Animals; Arterioles; Blotting, Western; Coronary Vessels; Cyclic GMP; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Guanylate Cyclase; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Nitroso Compounds; Obesity; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2008 |
Nitric oxide mediates hyperphagia of obese Zucker rats: relation to specific changes in the microstructure of feeding behavior.
Topics: Animals; Arginine; Body Weight; Dose-Response Relationship, Drug; Eating; Enzyme Inhibitors; Feeding Behavior; Hyperphagia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Rats; Rats, Zucker | 1996 |
Endothelial function of the mesenteric arteriole and mechanical behaviour of the carotid artery in rats with insulin resistance and hypercholesterolaemia.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Carotid Arteries; Compliance; Endothelium, Vascular; Hypercholesterolemia; Insulin Resistance; Male; NG-Nitroarginine Methyl Ester; Obesity; Rats; Rats, Zucker; Splanchnic Circulation; Vasomotor System | 1995 |
Inhibition of nitric oxide generation unmasks vascular dysfunction in insulin-resistant, obese JCR:LA-cp rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Platelets; Blood Pressure; Cyclic GMP; Diabetes Mellitus; Enzyme Inhibitors; Genotype; Insulin Resistance; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Penicillamine; Phenylephrine; Rats; S-Nitroso-N-Acetylpenicillamine; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Modulation of vasomotion in resistance arteries of JCR:LA-cp rats: a model of insulin resistance.
Topics: Animals; Insulin Resistance; Male; Meclofenamic Acid; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Obesity; Rats | 1999 |
Vascular wall dysfunction in JCR:LA-cp rats: effects of age and insulin resistance.
Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Blood Glucose; Body Weight; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eicosanoids; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Insulin; Insulin Resistance; Male; Meclofenamic Acid; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Obesity; Phenylephrine; Rats; Rats, Mutant Strains; Triglycerides; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Exercise enhances vasorelaxation in experimental obesity associated hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Analysis of Variance; Animals; Blood Glucose; Carotid Arteries; Cholesterol; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Hypertension; In Vitro Techniques; Insulin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Obesity; Physical Exertion; Rats; Rats, Zucker; Thromboxane B2; Triglycerides; Vasodilation; Vasodilator Agents | 1999 |
Endothelial dysfunction accompanies a pro-oxidant, pro-diabetic challenge in the insulin resistant, obese Zucker rat in vivo.
Topics: Acetylcholine; Animals; Antioxidants; Area Under Curve; Body Weight; Buthionine Sulfoximine; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Hydroquinones; Insulin Resistance; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Obesity; Oxidants; Rats; Rats, Zucker | 2000 |
Vascular wall function in insulin-resistant JCR:LA-cp rats: role of male and female sex.
Topics: Animals; Blood Glucose; Blood Vessels; Enzyme Inhibitors; Female; Genetic Linkage; Insulin; Insulin Resistance; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Obesity; Rats; Rats, Inbred Strains; Sex Characteristics; Triglycerides | 2000 |
The mechanism of resveratrol-induced vasorelaxation differs in the mesenteric resistance arteries of lean and obese rats.
Topics: Acetylcholine; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Indomethacin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Norepinephrine; Obesity; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Acute effect of the dual angiotensin-converting enzyme and neutral endopeptidase 24-11 inhibitor mixanpril on insulin sensitivity in obese Zucker rat.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Bradykinin; Bradykinin Receptor Antagonists; Drug Interactions; Enzyme Inhibitors; Glucose; Insulin Resistance; Male; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Rats; Rats, Zucker; Receptor, Bradykinin B2 | 2001 |
Interactions between nitric oxide and renal nerves in the excretion of a saline load in obese Zucker rats.
Topics: Animals; Blood Glucose; Diuresis; Enzyme Inhibitors; Guanidines; Hemodynamics; Indazoles; Kidney; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Rats; Rats, Zucker | 2001 |
Modulation of the leptin-induced white adipose tissue lipolysis by nitric oxide.
Topics: Adipose Tissue; Animals; Cells, Cultured; Chlorisondamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglionic Blockers; Leptin; Lipolysis; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Obesity; Penicillamine; Rats; Rats, Wistar; Rats, Zucker | 2001 |
Augmented adrenergic vasoconstriction in hypertensive diabetic obese Zucker rats.
Topics: Angiotensin II; Animals; Arteries; Arterioles; Blood Pressure; Diabetes Mellitus; Endothelins; Heart Rate; Hypertension; Male; Microcirculation; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Obesity; Phentolamine; Propranolol; Rats; Rats, Zucker; Thinness; Vasoconstriction | 2002 |
Investigation of basal endothelial function in the obese Zucker rat in vitro.
Topics: Animals; Antimetabolites; Antioxidants; Body Weight; Buthionine Sulfoximine; Endothelium, Vascular; Enzyme Inhibitors; Hydroquinones; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Oxidative Stress; Phenylephrine; Rats; Rats, Zucker; Superoxides; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Eating; Enzyme Inhibitors; Hypertriglyceridemia; Insulin; Lipid Metabolism; Lipids; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Obesity; Postprandial Period; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Species Specificity; Time | 2002 |