ng-nitroarginine methyl ester has been researched along with Endotoxin Shock in 81 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 44 (54.32) | 18.2507 |
2000's | 33 (40.74) | 29.6817 |
2010's | 4 (4.94) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Iskit, AB; Ozer, EK | 1 |
Chen, SJ; Kuo, JH; Lue, WM; Shih, CC; Wu, CC | 1 |
Chen, SJ; Li, SY; Liao, MH; Shih, CC; Wu, CC | 1 |
Hinohara, H; Kadoi, Y; Kawauchi, C; Mizutani, A; Saito, S; Tokue, A | 1 |
Qian, LB; Xia, ML; Xia, Q; Xu, C; Zhou, XM | 1 |
Bruce, IC; Wang, H; Xia, Q; Xu, C; Yi, C | 1 |
Harding, SE; Levin, M; Pathan, N; Sandiford, C | 1 |
Anvari, K; Fatehi, M; Fatehi-Hassanabad, Z | 1 |
Albertini, M; Clement, MG; Hussain, SN; Lafortuna, CL; Mazzola, S; Radice, S | 1 |
Bukan, N; Dursun, A; Engin, A; Kurukahvecioğlu, O | 1 |
Antunes-Rodrigues, J; Branco, LG; Carnio, EC; de Castro, M; Giusti-Paiva, A | 1 |
Bordet, R; Corseaux, D; Jude, B; Leclerc, J; Lund, N; Pu, Q; Vallet, B; Wiel, E | 1 |
Arendshorst, WJ; Boffa, JJ | 1 |
Assreuy, J; Duma, D; Silva-Santos, JE | 1 |
Adachi, Y; Miura, NN; Nameda, S; Ohno, N; Saito, M | 1 |
Helmer, KS; Kennison, SD; Mercer, DW; Robinson, EK; Suliburk, JW | 1 |
Ivanova, IV; Khromov, OS; Stefanov, OV | 1 |
Goto, F; Kadoi, Y | 1 |
Baumgarten, G; Ehrentraut, S; Fandrey, J; Frede, S; Grohé, C; Mengden, T; Meyer, R; Stapel, H | 1 |
Ikeda, M; Koga, K; Nanri, H; Sano, H; Sata, T; Shigematsu, A | 1 |
Becker, WK; Ciceri, DP; Offner, PJ; Pruitt, BA; Robertson, FM | 1 |
Gryglewski, RJ; Korbut, R; Vane, JR; Warner, TD | 1 |
Atkinson, AM; Teale, DM | 1 |
Dasta, JF; Wolfe, TA | 1 |
Chen, SJ; Szabó, C; Thiemermann, C; Vane, JR; Wu, CC | 1 |
Offner, PJ; Pruitt, BA; Robertson, FM | 1 |
Ayuse, T; Boitnott, JK; Brienza, N; Revelly, JP; Robotham, JL | 1 |
Hussain, SN | 1 |
Paya, D; Stoclet, JC | 1 |
Adams, HR; Parker, JL | 1 |
Gao, YQ; Hyman, A; Lippton, H; Spitzer, JJ; Wang, JF | 1 |
Fahey, TJ; Fantini, GA; Shires, GT; Yoshioka, T | 1 |
Adams, HR; Jones, JJ; Keller, RS; Kim, KF; Myers, PR; Parker, JL; Rubin, LJ | 1 |
Feihl, F; Hurni, JM; Liaudet, L; Markert, M; Perret, C; Rosselet, A | 1 |
Kanmura, Y; Tsuneyoshi, I; Yoshimura, N | 1 |
Maupoil, V; Paya, D; Rochette, L; Schott, C; Stoclet, JC | 1 |
Gerling, W; Michelsen, A; Schäfer, R; Schmucker, P; Wagner, K | 1 |
Cioffi, WG; Jordan, BS; Offner, PJ; Ogura, H; Pruitt, BA | 1 |
Aughey, EA; Burns, H; Fatehi-Hassanabad, Z; Furman, BL; Parratt, JR; Paul, A; Plevin, R | 1 |
Arkovitz, MS; Garcia, VF; Salzman, AL; Szabó, C; Vromen, A; Zingarelli, B | 1 |
Cohen, RI; Genovese, J; Huberfeld, S; Scharf, SM; Steinberg, HN | 1 |
Kilbourn, RG; Szabó, C; Traber, DL | 1 |
Chopin, C; Fourrier, F; Gosselin, B; Goudemand, J; Jourdain, M; Leroy, X; Mangalaboyi, J; Tournoys, A; Vallet, B | 1 |
Kiehl, MG; Kienast, J; Meyer, J; Ostermann, H | 1 |
Eigler, A; Endres, S | 1 |
Beauchamp, M; Delalandre, A; Filep, JG | 1 |
Goebels, J; Heremans, H; Kuschnaroff, LM; Matthys, P; Valckx, D; Waer, M | 1 |
Feihl, F; Liaudet, L; Markert, M; Perret, C; Rosselet, A; Schaller, MD | 1 |
Klemm, K; Moody, FG | 1 |
Avontuur, JA; Bruining, HA; Tutein Nolthenius, RP; van Bodegom, JW | 1 |
Avontuur, JA; Bruining, HA; Buijk, SL; Kanhai, KJ; Tutein Nolthenius, RP | 1 |
Avontuur, JA; Biewenga, M; Bruining, HA; Buijk, SL; Kanhai, KJ | 1 |
Filep, JG; Gagnon, C; Leblond, FA | 1 |
Avontuur, JA; Bruining, HA; Eggermont, AM; Jongen-Lavrencic, M; Stam, TC; van Amsterdam, JG | 1 |
Chen, SJ; Wu, CC; Yen, MH | 1 |
Avontuur, JA; Bruining, HA; Buijk, SL | 1 |
Avontuur, JA; Boomsma, F; Bruining, HA; de Jong, FH; van den Meiracker, AH | 1 |
Blomquist, S; Dahm, PL; Grins, E; Mårtensson, L; Myhre, E; Thörne, J | 1 |
Töre, FC; Tunçel, N | 1 |
Datta, P; Javeshghani, D; Levy, RD; Magder, S; Mehta, S | 1 |
Balk, RA; Symeonides, S | 1 |
Cochran, JB; Cook, JA; Genovese, F; Ogura, S; Teti, G | 1 |
Anning, PD; Evans, TW; Gray, P; Mitchell, JA; Warner, TD; Woods, M | 1 |
Ak, D; Sahintürk, V; Töre, F; Tunçel, M; Tunçel, N | 1 |
Chang, MS; Chen, CC; Chen, SA; Chiang, CE; Ding, PY; Lin, YC; Luk, HN | 1 |
Broccard, A; Eckert, P; Feihl, F; Hurni, JM; Lazor, R; Liaudet, L; Perret, C; Schaller, MD | 1 |
Chen, A; Chen, SJ; Chou, TC; Liao, MH; Wu, CC; Yen, MH | 1 |
Chen, SJ; Lin, CI; Wu, CC; Yang, SN; Yen, MH | 1 |
Cohen, RI; Davis, A; Loona, R; Scharf, SM; Shapir, Y | 1 |
Bourreau, J; Shan, Q | 1 |
Baykal, A; Guc, MO; Hascelik, G; Iskit, AB; Kavuklu, B; Sayek, I | 1 |
Bordet, R; Corseaux, D; Jude, B; Lund, N; Pu, Q; Robin, E; Vallet, B; Wiel, E | 1 |
Lamarque, D; Whittle, BJ | 1 |
Guc, MO; Iskit, AB | 1 |
Chen, HI; Kao, SJ; Lee, RP; Wang, D | 1 |
Javeshghani, D; Magder, S | 1 |
Albertini, M; Ciminaghi, B; Clement, MG; Mazzola, S | 1 |
Cohen, RI; Hassell, AM; Liu, SF; Marini, C; Marzouk, K; Scharf, SM | 1 |
Ogawa, R; Sakamoto, A; Suzuki, N | 1 |
Fatehi, M; Fatehi-Hassanabad, Z; Tanomand, A | 1 |
Estrada, C; Fernandez, A; Gonzalez, C; Martin, C; Moncada, S | 1 |
4 review(s) available for ng-nitroarginine methyl ester and Endotoxin Shock
Article | Year |
---|---|
Use of nitric oxide synthase inhibitors as a novel treatment for septic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Clinical Trials as Topic; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1995 |
Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: lessons learned from experimental and clinical studies.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Dogs; Drug Therapy, Combination; Enzyme Inhibitors; Free Radical Scavengers; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Rats; Rodentia; Shock, Septic | 1997 |
[Inhibition of nitric oxide synthase in septic shock. Therapeutic limits and perspectives].
Topics: Animals; Enzyme Inhibitors; Hemodynamics; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1997 |
Nitric oxide in the pathogenesis of sepsis.
Topics: Animals; Cardiovascular System; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Sepsis; Shock, Septic | 1999 |
4 trial(s) available for ng-nitroarginine methyl ester and Endotoxin Shock
Article | Year |
---|---|
Nitric oxide synthase inhibition by L-NAME in leukocytopenic patients with severe septic shock.
Topics: Adult; Analysis of Variance; Antineoplastic Agents; Blood Pressure; Enzyme Inhibitors; Female; Heart Ventricles; Hematologic Neoplasms; Hemodynamics; Humans; Leukopenia; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prospective Studies; Shock, Septic; Stroke Volume; Treatment Outcome; Vascular Resistance; Vasoconstrictor Agents | 1997 |
Prolonged inhibition of nitric oxide synthesis in severe septic shock: a clinical study.
Topics: Adult; Aged; APACHE; Critical Care; Enzyme Inhibitors; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prospective Studies; Shock, Septic; Treatment Outcome | 1998 |
Effect of L-NAME, an inhibitor of nitric oxide synthesis, on plasma levels of IL-6, IL-8, TNF alpha and nitrite/nitrate in human septic shock.
Topics: APACHE; Drug Monitoring; Female; Hemodynamics; Humans; Infusions, Intravenous; Interleukin-6; Interleukin-8; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Prospective Studies; Shock, Septic; Survival Analysis; Tumor Necrosis Factor-alpha | 1998 |
Distribution and metabolism of N(G)-nitro-L-arginine methyl ester in patients with septic shock.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrolysis; In Vitro Techniques; Injections, Intravenous; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Shock, Septic | 1998 |
73 other study(ies) available for ng-nitroarginine methyl ester and Endotoxin Shock
Article | Year |
---|---|
Effects of endothelin and nitric oxide on cardiac muscle functions in experimental septic shock model.
Topics: Animals; Bosentan; Carbachol; Cardiotonic Agents; Endothelin Receptor Antagonists; Endothelins; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Papillary Muscles; Rats, Wistar; Shock, Septic; Sulfonamides | 2016 |
Abnormal activation of potassium channels in aortic smooth muscle of rats with peritonitis-induced septic shock.
Topics: Animals; Aorta; Barium; Disease Models, Animal; Electrophysiology; KATP Channels; Male; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Peptides; Peritonitis; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Rats; Rats, Inbred WKY; Shock, Septic | 2009 |
NO contributes to abnormal vascular calcium regulation and reactivity induced by peritonitis-associated septic shock in rats.
Topics: Animals; Aorta, Thoracic; Boron Compounds; Calcium; Calcium Channel Blockers; Cecum; Indoles; Ligation; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Peritonitis; Rats; Rats, Wistar; Ryanodine; Shock, Septic | 2010 |
Comparison of the effects of vasopressin and norepinephrine on organ perfusion during septic shock in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Rats; Rats, Wistar; Renal Circulation; Shock, Septic; Splanchnic Circulation; Streptozocin; Vasopressins | 2010 |
[Effect of nitric oxide synthase inhibitors on the changes of hemodynamic parameters and aortic tension induced by septic shock in rats].
Topics: Animals; Aorta, Thoracic; Enzyme Inhibitors; Hemodynamics; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic | 2008 |
Mitochondrial nitric oxide synthase participates in septic shock myocardial depression by nitric oxide overproduction and mitochondrial permeability transition pore opening.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Indazoles; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Muscle Proteins; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Septic | 2012 |
Characterization of a myocardial depressant factor in meningococcal septicemia.
Topics: Adolescent; Animals; Cells, Cultured; Child; Child, Preschool; Cyclic GMP; Female; Humans; In Vitro Techniques; Infant; Interleukin-1; Leukocytes, Mononuclear; Male; Meningococcal Infections; Myocardial Contraction; Myocardial Depressant Factor; Myocytes, Cardiac; Neisseria meningitidis, Serogroup C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Sepsis; Shock, Septic; Tumor Necrosis Factor-alpha | 2002 |
The beneficial effects of protein tyrosine kinase inhibition on the circulatory failure induced by endotoxin in the rat.
Topics: Animals; Drug Interactions; Endotoxins; Enzyme Inhibitors; Genistein; Hemodynamics; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Phenylephrine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Sympathetic Nervous System; Vasoconstriction | 2002 |
Effect of NO synthase inhibition on cardiovascular and pulmonary dysfunction in a porcine short-term model of endotoxic shock.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Central Venous Pressure; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli; Guanidines; Heart Rate; Hemodynamics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen Consumption; Respiration; Shock, Septic; Swine; Time Factors; Vascular Resistance | 2002 |
[The effects of L-arginine and NG-nitro-L-arginine methylester on lipopolysaccharide and lipoteichoic acid induced liver injury in the rat].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Liver; Liver Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Teichoic Acids | 2003 |
Role of nitric oxide in thermoregulation during septic shock: involvement of vasopressin.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Body Temperature; Body Temperature Regulation; Enzyme Inhibitors; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Shock, Septic | 2003 |
Effects of the angiotensin-converting enzyme inhibitor perindopril on endothelial injury and hemostasis in rabbit endotoxic shock.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Gas Analysis; Disease Models, Animal; Endothelium, Vascular; Hemostasis; Immunohistochemistry; NG-Nitroarginine Methyl Ester; Perindopril; Rabbits; Regression Analysis; Shock, Septic; Statistics, Nonparametric | 2004 |
Maintenance of renal vascular reactivity contributes to acute renal failure during endotoxemic shock.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Arginine Vasopressin; Enzyme Inhibitors; Glomerular Filtration Rate; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Renal Circulation; Shock, Septic; Urine; Vasoconstrictor Agents | 2005 |
Inhibition of glucocorticoid receptor binding by nitric oxide in endotoxemic rats.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endotoxemia; Escherichia coli Infections; Female; Lipopolysaccharides; Liver; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Receptors, Glucocorticoid; S-Nitroso-N-Acetylpenicillamine; Shock, Septic; Spleen; Tyrosine Transaminase | 2004 |
Effect of nitric oxide on beta-glucan/indomethacin-induced septic shock.
Topics: Animals; beta-Glucans; Enzyme-Linked Immunosorbent Assay; Indomethacin; Interleukin-6; Liver; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Shock, Septic; Sizofiran; Tumor Necrosis Factor-alpha | 2005 |
Time-dependent aggravation or attenuation of lipopolysaccharide-induced gastric injury by nitric oxide synthase inhibition.
Topics: Animals; Drug Interactions; Enzyme Inhibitors; Gastric Juice; Lipopolysaccharides; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Shock, Septic; Stomach; Stomach Diseases; Time Factors | 2005 |
[Inhibition of nitric oxide synthesis during bacterial shock does not prevent development of resistant hypotension and death in rats].
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypotension; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Shock, Septic | 2005 |
Effects of selective iNOS inhibition on systemic hemodynamics and mortality rate on endotoxic shock in streptozotocin-induced diabetic rats.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Hemodynamics; Lipopolysaccharides; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Tyrosine | 2007 |
Antagonism of lipopolysaccharide-induced blood pressure attenuation and vascular contractility.
Topics: Animals; Aorta; Blood Pressure; Cytokines; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Isothiuronium; Lipopolysaccharides; Mice; Mice, Inbred C3H; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Point Mutation; RNA, Messenger; Shock, Septic; Signal Transduction; Sugar Phosphates; Time Factors; Toll-Like Receptor 4; Vasoconstriction | 2007 |
Role of nitric oxide during carrageenan-sensitized endotoxin shock in mice.
Topics: Animals; Arginine; Carrageenan; Dose-Response Relationship, Drug; Guanidines; Lipopolysaccharides; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ornithine Carbamoyltransferase; Shock, Septic | 1995 |
Detrimental hemodynamic effects of nitric oxide synthase inhibition in septic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiac Output; Central Venous Pressure; Escherichia coli; Female; Heart Rate; Hemodynamics; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Pulmonary Wedge Pressure; Resuscitation; Shock, Septic; Sodium Chloride; Swine; Vascular Resistance | 1994 |
The effect of nitric oxide synthase inhibition on the plasma fibrinolytic system in septic shock in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Coagulation; Disseminated Intravascular Coagulation; Fibrinogen; Fibrinolysis; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Plasminogen Inactivators; Platelet Count; Rats; Rats, Wistar; Shock, Septic | 1994 |
L-canavanine restores blood pressure in a rat model of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Canavanine; Enzyme Induction; Escherichia coli; Heart Rate; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Shock, Septic | 1994 |
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Guanidines; Heart Rate; Hypotension; Lipopolysaccharides; Male; Mice; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Wistar; Shock, Septic; Time Factors | 1995 |
Effects of nitric oxide synthase inhibition on regional blood flow in a porcine model of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiac Output; Carotid Arteries; Disease Models, Animal; Escherichia coli Infections; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Regional Blood Flow; Renal Circulation; Resuscitation; Shock, Septic; Splanchnic Circulation; Swine | 1995 |
Role of nitric oxide in porcine liver circulation under normal and endotoxemic conditions.
Topics: Animals; Arginine; Blood Flow Velocity; Disease Models, Animal; Endotoxins; Hepatic Artery; Liver Circulation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Portal Vein; Shock, Septic; Swine | 1995 |
Role of nitric oxide in endotoxin-induced metabolic and vascular dysregulation of the canine diaphragm.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Diaphragm; Dogs; Endotoxins; Escherichia coli; Hypotension; Infusions, Intra-Arterial; Injections, Intravenous; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen Consumption; Regional Blood Flow; Shock, Septic; Vascular Resistance; Vasodilation | 1995 |
Involvement of bradykinin and nitric oxide in the early hemodynamic effects of lipopolysaccharide in rats.
Topics: Animals; Arginine; Bradykinin; Bradykinin Receptor Antagonists; Hemodynamics; Hypotension; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Rats; Rats, Wistar; Receptor, Bradykinin B2; Shock, Septic | 1995 |
Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Calcimycin; Endothelium, Vascular; Escherichia coli; Guinea Pigs; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Shock, Septic; Substance P; Vasodilation | 1993 |
The roles of nitric oxide and hydrogen peroxide production in lipopolysaccharide-induced intestinal damage.
Topics: Animals; Arginine; Cardiac Output; Colon; Hemodynamics; Hydrogen Peroxide; Intestine, Small; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Stereoisomerism; Vascular Resistance | 1994 |
The role of tumor necrosis factor and nitric oxide in the acute cardiovascular response to endotoxin.
Topics: Animals; Arginine; Cardiovascular Diseases; Endotoxins; Enzyme Inhibitors; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Septic; Toxemia; Tumor Necrosis Factor-alpha | 1996 |
Endotoxin-induced myocardial dysfunction: is there a role for nitric oxide?
Topics: Animals; Arginine; Enzyme Inhibitors; Guanidines; Guinea Pigs; Heart Atria; Immunoenzyme Techniques; Lipopolysaccharides; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1995 |
Beneficial effects of L-canavanine, a selective inhibitor of inducible nitric oxide synthase, during rodent endotoxaemia.
Topics: Acidosis, Lactic; Animals; Arginine; Blood Pressure; Canavanine; Heart Rate; Lipopolysaccharides; Male; Mice; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Rats; Rats, Wistar; Shock, Septic | 1996 |
Nitric oxide as a mediator of reduced arterial responsiveness in septic patients.
Topics: Aged; Arginine; Enzyme Inhibitors; Female; Hemodynamics; Humans; Hypotension; Mesenteric Arteries; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Shock, Septic; Vasoconstriction | 1996 |
Temporal relationships between levels of circulating NO derivatives, vascular NO production and hyporeactivity to noradrenaline induced by endotoxin in rats.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Norepinephrine; Rats; Rats, Wistar; Shock, Septic; Time Factors | 1995 |
Comparison between conventional hemodynamic monitoring and polarographic tissue pO2-monitoring of the liver in early septicemia of the pig.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Hemodynamics; Liver; Liver Circulation; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Oxygen; Oxygen Consumption; Polarography; Sepsis; Shock, Septic; Swine | 1996 |
Cardiopulmonary effects of combined nitric oxide inhibition and inhaled nitric oxide in porcine endotoxic shock.
Topics: Administration, Inhalation; Animals; Endotoxemia; Enzyme Inhibitors; Female; Heart; Hemodynamics; Hypertension, Pulmonary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Respiration; Shock, Septic; Swine | 1996 |
Effects of L-canavanine, an inhibitor of inducible nitric oxide synthase, on endotoxin mediated shock in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Canavanine; Cerebellum; Dose-Response Relationship, Drug; Endotoxins; Kidney; Lung; Male; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Sprague-Dawley; Shock, Septic; Spleen; Vasoconstrictor Agents | 1996 |
Low-level expression and limited role for the inducible isoform of nitric oxide synthase in the vascular hyporeactivity and mortality associated with cecal ligation and puncture in the rat.
Topics: Animals; Aorta, Thoracic; Cecum; Enzyme Inhibitors; Guanidines; Isoenzymes; Ligation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Punctures; Rats; Rats, Sprague-Dawley; Shock, Septic; Time Factors; Vascular Resistance | 1996 |
A comparison between the acute effects of nitric oxide synthase inhibition and fluid resuscitation on myocardial function and metabolism in entotoxemic dogs.
Topics: Animals; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Fluid Therapy; Hemodynamics; Lipopolysaccharides; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Resuscitation; Shock, Septic | 1996 |
Effects of N omega-nitro-L-arginine methyl ester on the endotoxin-induced disseminated intravascular coagulation in porcine septic shock.
Topics: Animals; Disease Models, Animal; Disseminated Intravascular Coagulation; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Female; Hemodynamics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Severity of Illness Index; Shock, Septic; Swine | 1997 |
Dual role for nitric oxide in the regulation of plasma volume and albumin escape during endotoxin shock in conscious rats.
Topics: Animals; Blood Pressure; Capillary Permeability; Endotoxemia; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasma Volume; Rats; Rats, Wistar; Serum Albumin; Shock, Septic | 1997 |
Increased mortality and impaired clonal deletion after staphylococcal enterotoxin B injection in old mice: relation to cytokines and nitric oxide production.
Topics: Aging; Animals; Antigens, Bacterial; Clonal Anergy; Clonal Deletion; Cytokines; Enterotoxins; Enzyme Inhibitors; Fas Ligand Protein; Gene Expression Regulation; Immunization; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Killer Cells, Natural; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; RNA, Messenger; Shock, Septic; Staphylococcus aureus; Superantigens; Tumor Necrosis Factor-alpha | 1997 |
Nonselective versus selective inhibition of inducible nitric oxide synthase in experimental endotoxic shock.
Topics: Animals; Canavanine; Enzyme Inhibitors; Female; L-Lactate Dehydrogenase; Lipase; Lipopolysaccharides; Liver; Mice; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Shock, Septic; Transaminases | 1998 |
Regional intestinal blood flow and nitric oxide synthase inhibition during sepsis in the rat.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Intestinal Mucosa; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Time Factors | 1998 |
Effect of L-NAME, an inhibitor of nitric oxide synthesis, on cardiopulmonary function in human septic shock.
Topics: Enzyme Inhibitors; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prospective Studies; Pulmonary Gas Exchange; Shock, Septic | 1998 |
Pulmonary hypertension and reduced cardiac output during inhibition of nitric oxide synthesis in human septic shock.
Topics: Aged; Cardiac Output; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension, Pulmonary; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pilot Projects; Shock, Septic | 1998 |
Peroxynitrite production by human neutrophils, monocytes and lymphocytes challenged with lipopolysaccharide.
Topics: Adult; Enzyme Inhibitors; Female; Guanidines; Humans; Lipopolysaccharides; Lymphocytes; Male; Middle Aged; Monocytes; Neutrophils; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Oxidants; Oxidation-Reduction; Rhodamines; Shock, Septic | 1998 |
Nitric oxide-independent activation of soluble guanylyl cyclase contributes to endotoxin shock in rats.
Topics: Animals; Aorta; Blood Pressure; Charybdotoxin; Dexamethasone; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Guanidines; Guanylate Cyclase; Heart Rate; In Vitro Techniques; Lipopolysaccharides; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred WKY; Shock, Septic; Tetraethylammonium | 1998 |
Endothelin-1 and blood pressure after inhibition of nitric oxide synthesis in human septic shock.
Topics: Blood Pressure; Endothelin-1; Female; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Shock, Septic; Vascular Resistance | 1999 |
Intestinal and hepatic perfusion and metabolism in hypodynamic endotoxic shock. Effects of nitric oxide synthase inhibition.
Topics: Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia coli; Female; Hemodynamics; Hepatic Artery; Hypertension, Pulmonary; Intestine, Small; Lactates; Lipopolysaccharides; Liver; Lung; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Portal Vein; Regional Blood Flow; Shock, Septic; Survival Rate; Swine; Vascular Resistance; Vasoconstrictor Agents; Ventricular Function, Left | 1999 |
The effect of vasoactive intestinal peptide (VIP) and inhibition of nitric oxide synthase on survival rate in rats exposed to endotoxin shock.
Topics: Analysis of Variance; Animals; Blood Pressure; Escherichia coli; Female; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Septic; Time Factors; Vasoactive Intestinal Peptide | 1998 |
Porcine endotoxemic shock is associated with increased expired nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Models, Animal; DNA Primers; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia coli; Hemodynamics; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Polymerase Chain Reaction; Respiration; Shock, Septic; Swine; Time Factors | 1999 |
Effect of nitric oxide donors and nitric oxide synthase inhibitors in neonatal rat endotoxic shock.
Topics: Animals; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Female; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Septic; Spleen; Thiourea | 1999 |
Effects of nitric oxide-modulating amino acids on coronary vessels: relevance to sepsis.
Topics: Animals; Arginine; Coronary Vessels; Endothelin-1; Endotoxins; Enzyme Induction; Glutamine; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; RNA, Messenger; Shock, Septic | 2000 |
Vasoactive intestinal peptide inhibits degranulation and changes granular content of mast cells: a potential therapeutic strategy in controlling septic shock.
Topics: Animals; Antioxidants; Catalase; Cell Degranulation; Female; Histamine; Kidney; Lipid Peroxidation; Liver; Male; Mast Cells; Methylhistamines; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Shock, Septic; Superoxide Dismutase; Vasoactive Intestinal Peptide | 2000 |
Shortening of cardiac action potentials in endotoxic shock in guinea pigs is caused by an increase in nitric oxide activity and activation of the adenosine triphosphate-sensitive potassium channel.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guinea Pigs; Lipopolysaccharides; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Papillary Muscles; Potassium Channels; Shock, Septic; Time Factors | 2000 |
Tissue oxygenation and hemodynamic response to NO synthase inhibition in septic shock.
Topics: Adrenergic Agonists; Adult; Aged; Cell Hypoxia; Drug Evaluation; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hemodynamics; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen Consumption; Prospective Studies; Shock, Septic; Treatment Outcome | 2000 |
Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Drug Interactions; Endotoxemia; Enzyme Induction; Enzyme Inhibitors; Hemodynamics; Interleukin-10; Lipopolysaccharides; Liver; Lung; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth, Vascular; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norepinephrine; Rats; Rats, Inbred WKY; Shock, Septic; Terbutaline; Tumor Necrosis Factor-alpha; Vascular Resistance | 2000 |
Abnormal activation of K(+) channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence.
Topics: Animals; Aorta; Apamin; Benzimidazoles; Charybdotoxin; Drug Interactions; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Hypotension; Lipopolysaccharides; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pinacidil; Potassium Channels; Quinoxalines; Rats; Rats, Inbred WKY; Shock, Septic; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2000 |
Comparison between selective and nonselective nitric oxide synthase inhibition and phenylephrine in normal and endotoxic swine.
Topics: Animals; Cardiotonic Agents; Enzyme Inhibitors; Female; Hemodynamics; Isothiuronium; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Shock, Septic; Swine | 2000 |
Cardiac and vascular effects of nitric oxide synthase inhibition in lipopolysaccharide-treated rats.
Topics: Animals; Aorta; Calcium; Enzyme Inhibitors; Guanidines; Heart; In Vitro Techniques; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Shock, Septic; Vasoconstriction | 2000 |
Experimental study of the effect of nitric oxide inhibition on mesenteric blood flow and interleukin-10 levels with a lipopolysaccharide challenge.
Topics: Animals; Female; Guanidines; Interleukin-10; Lipopolysaccharides; Mesentery; Mice; Mice, Inbred Strains; Multiple Organ Failure; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Regional Blood Flow; Shock, Septic | 2000 |
Effect of L-arginine on endothelial injury and hemostasis in rabbit endotoxin shock.
Topics: Acetylcholine; Animals; Arginine; Blood Gas Analysis; Calcimycin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hemostasis; Ionophores; Lipopolysaccharides; Male; Monocytes; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenylephrine; Rabbits; Shock, Septic; Thromboplastin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Weight Loss | 2000 |
Increase in gastric intramucosal hydrogen ion concentration following endotoxin challenge in the rat and the actions of nitric oxide synthase inhibitors.
Topics: Animals; Endotoxins; Enzyme Inhibitors; Gastric Mucosa; Hydrogen-Ion Concentration; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats; Shock, Septic | 2001 |
The timing of endothelin and nitric oxide inhibition affects survival in a mice model of septic shock.
Topics: Animals; Antihypertensive Agents; Bosentan; Canavanine; Disease Models, Animal; Endothelin Receptor Antagonists; Endotoxins; Enzyme Inhibitors; Guanidines; Lipopolysaccharides; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Shock, Septic; Sulfonamides; Survival Rate | 2001 |
The lung is the major site that produces nitric oxide to induce acute pulmonary oedema in endotoxin shock.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Body Weight; Dexamethasone; Enzyme Inhibitors; Escherichia coli; Guanidines; Lipopolysaccharides; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Size; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Shock, Septic | 2001 |
Regional changes in constitutive nitric oxide synthase and the hemodynamic consequences of its inhibition in lipopolysaccharide-treated pigs.
Topics: Animals; Blood Pressure; Blotting, Northern; Blotting, Western; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Shock, Septic; Swine; Vascular Resistance | 2001 |
Improvement of respiratory function by bosentan during endotoxic shock in the pig.
Topics: Animals; Antihypertensive Agents; Bosentan; Enzyme Inhibitors; Female; Hypertension, Pulmonary; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Edema; Respiration; Shock, Septic; Sulfonamides; Swine; Time Factors | 2001 |
Renal effects of nitric oxide in endotoxemia.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Endotoxemia; Female; Glomerular Filtration Rate; Isothiuronium; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Renal Circulation; Resuscitation; Shock, Septic; Swine | 2001 |
Effect of L-canavanine, an Inhibitor of inducible nitric oxide synthase, on myocardial dysfunction during septic shock.
Topics: Animals; Canavanine; Coronary Circulation; Heart; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Shock, Septic | 2002 |
Effects of endotoxin-induced shock on withdrawal contractions in the Guinea-pig isolated ileum.
Topics: Animals; Endotoxins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; NG-Nitroarginine Methyl Ester; Shock, Septic; Substance Withdrawal Syndrome | 2002 |
Nitric oxide from endothelium and smooth muscle modulates responses to sympathetic nerve stimulation: implications for endotoxin shock.
Topics: Acetylcholine; Animals; Arginine; Cycloheximide; Dexamethasone; Dinoprost; Endothelium, Vascular; Endotoxins; Iliac Artery; In Vitro Techniques; Interferon-gamma; Isometric Contraction; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Shock, Septic | 1992 |