ng-nitroarginine methyl ester has been researched along with Disease Models, Animal in 989 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 152 (15.37) | 18.2507 |
2000's | 416 (42.06) | 29.6817 |
2010's | 367 (37.11) | 24.3611 |
2020's | 54 (5.46) | 2.80 |
Authors | Studies |
---|---|
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Abdelhady, SA; Darwish, IE; El-Deeb, NM; El-Mas, MM; Gowayed, MA; Habib, YH | 1 |
Abuiessa, SA; El-Gowelli, HM; El-Gowilly, SM; El-Mas, MM; Helmy, MM | 1 |
Chen, P; Li, M; Shi, X; Wang, H | 1 |
Abbaszadeh, F; Fakhri, S; Farzaei, MH; Mohammadi, S; Mohammadi-Farani, A | 1 |
Fazli-Tabaei, S; Khakpai, F; Zarrindast, MR | 1 |
Joshi, S; Nema, J; Randhir, K; Sundrani, D; Wadhwani, N | 1 |
Boarescu, I; Boarescu, PM; Bocșan, IC; Bolboacă, SD; Bulboacă, AE; Buzoianu, AD; Mada, RO; Neagu, N; Pop, RM; Popa, ID; Roşian, ŞH; Rus, V | 1 |
Chen, L; Huang, X; Huang, Z; Li, J; Lye, S; Shen, X; Wang, C; Wang, Q; Wang, Z; Wei, Y; Xie, L; Xu, Y; Yue, X | 1 |
Gouveia, A; Lagace, D; Lui, M; Wang, J | 1 |
Castañeda-Lopez, ME; Castruita-De la Rosa, C; Delgado-Enciso, I; Flores-Mendoza, J; Garza-Veloz, I; Martinez-Fierro, ML; Rodriguez-Sanchez, IP; Wasike, D | 1 |
Bao, C; Chen, A; Han, Y; Liang, S; Pan, Y; Tang, H; Wang, X | 1 |
Huang, B; Lang, Q; Tian, M; Wei, J; Wei, S; Yu, X; Zhang, J; Zhao, C | 1 |
Beard, S; Binder, NK; Brownfoot, FC; Cuffe, JS; de Alwis, N; Fato, BR; Hannan, NJ; Kadife, E; Kaitu'u-Lino, TJ; Keenan, E; Mangwiro, YT; Marshall, SA | 1 |
Amini, A; Dehpour, AR; Jourian, S; Manavi, MA; Mohammad Jafari, R; Pahlevan-Fallahy, MT; Rahimi, M | 1 |
Doiron, JE; Goodchild, TT; Koul, K; LaPenna, KB; Lefer, DJ; Li, Z; Moles, K; Patel, RB; Polhemus, DJ; Shah, SJ; Sharp, TE; Wang, JS; Xia, H | 1 |
Adriouch, S; Boffa, JJ; Caron, J; Chadjichristos, CE; Chatziantoniou, C; Desterke, C; Fellahi, S; Ghachem, K; Lorenzo, HK; Mohamadou, I; Placier, S; Prakoura, N; Roger, E; Sahiri, V; Serre, J; Zhang, L | 1 |
Balkan, W; Cai, R; Dulce, RA; Hare, JM; Kanashiro-Takeuchi, RM; Kazmierczak, K; Schally, AV; Sha, W; Takeuchi, LM | 1 |
Behr, B; Dadras, M; Goertz, O; Lehnhardt, M; Sogorski, A; Voigt, M; von Glinski, M; Wallner, C | 1 |
Aderibigbe, AO; Ajayi, AM; Ben-Azu, B; Iwalewa, EO; Umukoro, S | 1 |
Ashitomi, K; Kadekawa, K; Nishijima, S; Noguchi, K; Okitsu, S; Sakanashi, M; Sugaya, K; Yamamoto, H | 1 |
Huang, J; Kong, H; Su, Y; Wang, F; Xin, H; Zheng, L | 1 |
Aydoğdu, N; Kandemir, N; Kaya, O; Taştekin, E; Tayfur, P; Yalçınkaya Yavuz, Ö | 1 |
Jan-On, G; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Sangartit, W; Sattayasai, J; Senaphan, K | 1 |
Chen, F; Chen, X; Li, C; Liang, X; Liao, Y; Pan, Y; Qiu, Z; Wei, Y; Wu, D; Yan, X; Yang, S; Zhang, K; Zhou, Y; Zhou, Z | 1 |
Breyer, RM; Carver, LS; do Carmo, LS; Harrison, DG; Itani, HA; Xiao, L | 1 |
Gillette, TG; Hill, JA; Jiang, N; Lavandero, S; May, HI; Schiattarella, GG; Tong, D | 1 |
Camargos, ERS; da Silva Oliveira, B; Ferreira, RN; Martinelli, PM; Marzano, ACS; Marzano, LAS; Miranda, AS; Rachid, MA; Simões E Silva, AC; Teixeira, AL | 1 |
Ahmed, OAA; Azhar, AS; El-Bassossy, HM; El-Mas, MM; Tarkhan, MM | 1 |
Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F; Sotomayor-Zárate, R | 1 |
Bunbupha, S; Kukongviriyapan, U; Maneesai, P; Pakdeechote, P; Rattanakanokchai, S; Tong-Un, T; Wunpathe, C | 1 |
Andersson, DC; Carlström, M; Cordero-Herrera, I; Guimarães, DD; Han, H; Lundberg, JO; McCann Haworth, S; Moretti, C; Uribe Gonzalez, AE; Weitzberg, E; Zhuge, Z | 1 |
Paulus, WJ | 1 |
Albuquerque, AAS; Capellini, VK; Carvalho, MTM; Celotto, AC; Evora, PRB; Ferreira, LG | 1 |
Baig, MS; Roy, A; Saqib, U; Wary, K | 1 |
Aluko, EO; Fasanmade, AA; Omobowale, TO; Oyagbemi, AA | 1 |
Adedapo, AA; Adedapo, ADA; Ajayi, AM; Ekwunife, NL; Falayi, OO; Omobowale, TO; Oyagbemi, A | 1 |
Castania, JA; Dias, DPM; Domingos-Souza, G; Fazan, R; Ferreira, NS; Martinez, D; Meschiari, CA; Pereira, CA; Santos-Almeida, FM; Silva, LEV; Tostes, RC | 1 |
Li, Y; Tao, L; Wang, C; Wang, J | 1 |
Ivo, ML; Monteiro, GM; Parisotto, EB; Ramalho, RT; Rodrigues, CT; Santos Neto, ATD; Silva, IS | 1 |
Jiang, Z; Zuo, J | 1 |
Arcanjo, DDR; Cavalcante, GL; da Silva, MTB; Ferreira, FN; Filho, ALMM; Sabino, JPJ; Soriano, RN | 1 |
Banks, WA; Cook, DG; Herbert, MJ; Keene, CD; Logsdon, AF; Marshall, DA; Meabon, JS; Perl, DP; Peskind, ER; Raskind, MA; Schindler, AG; Yagi, M | 1 |
Joo Turoni, CM; Marañón, RO; Peral de Bruno, M | 1 |
Ahmadi-Zeidabadi, M; Jeddi, S; Kohlmeier, KA; Mohammadi, F; Shabani, M | 1 |
Phachonpai, W; Tongun, T | 1 |
Andereggen, L; Kashefiolasl, S; Konczalla, J; Marbacher, S; Mrosek, J; Wanderer, S | 1 |
Ajebli, M; Eddouks, M | 1 |
Avdeeva, E; Avdeeva, N; Beskhmelnitsyna, E; Bushueva, O; Denisyuk, T; Golubev, I; Gudyrev, O; Gureev, V; Korokin, M; Korokina, L; Lazareva, G; Peresypkina, A; Pobeda, A; Pokrovskaia, T; Pokrovskii, M; Soldatov, V; Zatolokina, M | 1 |
Balenovic, I; Blagaic, AB; Cilic, M; Drmic, D; Filipcic, I; Ilic, S; Kokot, A; Seiwerth, S; Sikiric, P; Strbe, S; Tvrdeic, A; Vukojevic, J; Zemba Cilic, A; Zemba, M; Zoricic, Z | 1 |
Alexander-Lindo, R; Cifuentes, F; Delgoda, R; Francis, S; Gordon, A; Minott-Kates, D; Nwokocha, CR; Nwokocha, M; Palacios, J; Paredes, A; Thompson, R; Watson, J; Yakubu, MA | 1 |
Kamkar-Del, Y; Mohebbati, R; Shafei, MN | 1 |
Joshi, S; Nema, J; Sundrani, D | 1 |
Acikel-Elmas, M; Arbak, S; Cilingir, S; Gemici, M; Kolgazi, M; Ozer, S; Suyen, GG; Yazar, H; Yilmaz, O | 1 |
Blanco-Rivero, J; Camacho-Rodríguez, L; Cros-Brunsó, L; García-Redondo, AB; Llévenes, P; Martínez-González, Á; Salaices, M | 1 |
Chen, JS; Chen, JW; Huang, PH; Huang, WP; Lin, SJ; Yin, WH | 1 |
Chen, L; Hu, H; Li, H; Lin, M; Liu, M; Ma, J; Quan, S | 1 |
Abdulla, MH; Ahmad, A; Ahmad, FU; Akhtar, S; Chia, TY; Hassan, Z; Johns, EJ; Kaur, G; Khan, NA; Mei, HY; Murugaiyah, V; Sattar, MA | 1 |
Adler, J; Aïssi, D; Duque Escobar, J; Längst, N; Lukowski, R; Müller, C; Schweigert, O; Tong, T; Trégouët, DA; Zeller, T | 1 |
Ahad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Alam, MA; Bin Jardan, YA; Raish, M | 1 |
Ali, NA; El Gendy, ANG; Farrag, AH; Mohamed, SH; Ragab, TIM; Shalaby, ASG; Shalby, AB | 1 |
Honda, K; Iwata, K; Kamio, N; Nagashima, H; Sato, S; Shinoda, M; Sugano, N; Suzuki, T; Watanabe, M | 1 |
Jang, JH; Jin, CL; Kim, SJ; Oh, GT; Wu, YN; Zhang, YH; Zhao, ZH | 1 |
Abo-Elmatty, DM; El-Baz, AA; Ibrahim, A; Mosaad, SM; Moustafa, YM; Zaitone, SA | 1 |
Berg, G; Bertera, FM; Carranza, A; Chiappetta, DA; Del Mauro, JS; Donato, M; Fernandez Machulsky, N; Gelpi, RJ; González, GE; Gorzalczany, SB; Höcht, C; Morales, C; Morettón, MA; Prince, PD; Taira, CA | 1 |
Adamcova, M; Aziriova, S; Balazova, L; Celec, P; Krajcirovicova, K; Pechanova, O; Repova, K; Simko, F; Tothova, L; Vrankova, S; Zorad, S | 1 |
Bauk, L; Drmic, D; Ilic, S; Kolenc, D; Luetic, K; Seiwerth, S; Sever, M; Sikiric, P; Suran, J; Zenko Sever, A | 1 |
Ashabi, G; Khodagholi, F; Nourshahi, M; Salehpour, M; Zeinaddini Meymand, A | 1 |
Cheng, Y; Hong, F; Song, L; Wang, J; Xu, M; Zan, J; Zhao, J; Zou, R | 1 |
Chang, W; Li, J; Xu, N; Yuan, W; Zhang, W | 1 |
Lei, Y; Song, M; Sun, X; Wu, J | 1 |
Li, G; Liu, Y; Yan, D; Zhang, H; Zhang, Y; Zhao, L | 1 |
Bahremand, T; Dehpour, AR; Noorian, AR; Payandemehr, B; Payandemehr, P; Riazi, K; Sharifzadeh, M | 1 |
Castilla, D; Lassance-Soares, RM; Li, Y; Liu, ZJ; Parikh, PP; Regueiro, M; Shao, H; Vazquez-Padron, R; Velazquez, OC; Webster, KA | 1 |
Boeing, T; da Rosa, RL; da Silva, LM; de Almeida, CL; de Andrade, SF; de Medeiros Amorim Krueger, C; de Souza, P; Filho, VC; Mariano, LNB; Somensi, LB | 1 |
Bagwell, JM; Csiszar, A; Farkas, E; Fülöp, GA; Hertelendy, P; Kiss, T; O'Connor, D; Sorond, F; Tarantini, S; Ungvari, Z; Valcarcel-Ares, MN; Yabluchanksiy, A | 1 |
Belluardo, N; Caciagli, F; Ciccarelli, R; Condorelli, DF; Di Iorio, P; Frinchi, M; Jinnah, HA; Mudò, G; Mulè, F; Nuzzo, D; Serio, R; Zizzo, MG | 1 |
Antunovic, M; Bilic, Z; Drmic, D; Duzel, A; Gojkovic, S; Kasnik, K; Knezevic, M; Kokot, A; Kolovrat, M; Kralj, T; Krezic, I; Lojo, N; Malekinusic, D; Samara, M; Seiwerth, S; Sever, M; Sikiric, P; Siroglavic, M; Vidovic, T; Vlainic, J; Vrdoljak, B; Vukojevic, J | 1 |
Aydin, S; Cengelli Unel, C; Donertas, B; Erol, K; Kaygisiz, B; Ozatik, O; Ulupinar, E; Yildirim, E | 1 |
Acar, N; Keles-Celik, N; Sekerci, R; Tepekoy, F; Ustunel, I | 1 |
Huai, J; Wang, GJ; Yang, Z; Yi, YH | 1 |
Alboghobeish, S; Amirgholami, N; Cauli, O; Ghorbanzadeh, B; Houshmand, G; Mansouri, MT; Naghizadeh, B | 1 |
Bentzer, P; Dolinina, J; Öberg, CM; Rippe, A | 1 |
Harada, S; Liu, K; Matsuura, W; Nishibori, M; Tokuyama, S | 1 |
Dong, HP; He, ZZ; Ma, XX; Wang, ZH; Zhou, W | 1 |
Jin, Y; Li, L; Liu, XW; Sun, CJ; Zhang, WY | 1 |
Khattab, MA; Osman, AH; Shafik, AN | 1 |
Akindahunsi, AA; Bottari, NB; Carvalho, FB; da Costa, P; Lopes, TF; Morsch, VM; Oboh, G; Olabiyi, AA; Schetinger, MR; Stefanelo, N | 1 |
Bansal, N; Kumar, M | 1 |
Chen, L; Cheng, H; Endler, A; Li, Q; Shibasaki, F; Yao, B | 1 |
Fonteles, MC; Gonzaga-Silva, LF; Linhares, BL; Marinho, LB; Moraes, MO; Nascimento, NRF; Reges, R; Santos, CF; Silva, APG | 1 |
Kumei, S; Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K | 1 |
Adedara, IA; Adeyemo, MO; Ajibade, TO; Alake, SE; Farombi, EO; Olajide, LO | 1 |
Duan, MX; Liao, HH; Liu, C; Meng, YY; Tang, QZ; Wu, QQ; Xiao, Y; Yang, Z; Yuan, Y | 1 |
Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD | 1 |
Barančík, M; Berenyiová, A; Dovinová, I; Hrabárová, E; Jansen, E; Kvandová, M; Majzúnová, M | 1 |
Kim, JE; Lee, DS | 1 |
Maslov, LN; Naryzhnaya, NV | 1 |
Ahishali, B; Arican, N; Elmas, I; Gürses, C; Kaya, M; Kucuk, M; Orhan, N; Ugur Yilmaz, C | 1 |
Heiss, C; Kelm, M; Nicolaus, C; Sansone, R; Schuler, D | 1 |
Chen, JR; Huang, WC; Ko, J; Yang, HY; Yeh, WJ | 1 |
Dreier, JP; Hirayama, Y; Hiyoshi, K; Inoue, T; Ishihara, H; Kawano, A; Kawano, R; Kiyohira, M; Maruta, Y; Nomura, S; Oka, F; Okazaki, K; Oku, T; Sadahiro, H; Shinoyama, M; Shirao, S; Suehiro, E; Sugimoto, K; Suzuki, M; Yoneda, H | 1 |
Basiri, S; Enayati, A; Ghorghanlu, S; Khori, V; Mazaheri, Z; Pourabouk, M; Rajaei, M; Yassa, N | 1 |
Chen, Y; Deng, B; Hu, Q; Huang, Q; Ke, X; Nie, R; Wang, J; Xie, S; Zhang, T | 1 |
Bagatini, MD; Belló-Klein, A; Cardoso, AM; Carvalho, F; Gutierres, JM; Manfredi, LH; Morsch, VM; Rubin, MA; Schetinger, MRC; Sévigny, J; Tremblay, A; Zanini, D | 1 |
Amic, E; Amic, F; Bilic, Z; Boban Blagaic, A; Drmic, D; Horvat Pavlov, K; Klicek, R; Kokot, A; Krezic, I; Milkovic Perisa, M; Pajtak, A; Peklic, M; Rakic, M; Seiwerth, S; Sikiric, P; Tvrdeic, A; Vidovic, T; Zizek, H; Zovak, M | 1 |
Antunovic, M; Drmic, D; Horvat Pavlov, K; Jeyakumar, J; Malekinusic, D; Milkovic Perisa, M; Ruzman, J; Samara, M; Seiwerth, S; Sikiric, P; Vidovic, T; Vrdoljak, B | 1 |
Hirohata, S; Kitamori, K; Kumazaki, S; Mori, M; Sato, I; Watanabe, S; Yamamoto, S; Yamori, Y | 1 |
Jiang, Y; Jiang, Z; Li, S; Liu, F; Qu, H; Sun, L; Wang, S; Wang, X; Wang, Y; Wu, D; Xu, Y; Yu, X; Zou, Y | 1 |
Barreira, MA; Carvalho, MF; Fechine, FVJ; Gonzaga-Silva, LF; Oliveira, RRM; Pamplona, TL | 1 |
Baumbach, J; Casas, AI; Egea, J; Elbatreek, M; Gomez-Rangel, V; Guney, E; Hassan, AA; Kleikers, PWM; Larsen, SJ; López, MG; Schmidt, HHHW | 1 |
Gu, S; Hua, X; Mou, Z; Ni, J; Shen, H; Zheng, T; Zhou, Y | 1 |
Haefliger, JA; Kurtz, A; Le Gal, L; Mazzolai, L; Meda, P; Pellegrin, M; Santoro, T; Wagner, C | 1 |
Altamirano, F; French, KM; Gillette, TG; Hahn, VS; Hill, JA; Hill, TM; Huang, J; Jiang, N; Kass, DA; Kim, SY; Lavandero, S; Lee, DI; Luo, X; Mammen, PPA; May, HI; Schiattarella, GG; Sharma, K; Tong, D; Villalobos, E; Wang, ZV | 1 |
Jiang, XJ; Li, Y; Lin, QF; Lu, SF | 1 |
Ishimoto, T; Kadomatsu, K; Kato, N; Katsuno, T; Kosugi, T; Maeda, K; Maruyama, S; Masuda, T; Nagaya, H; Ryuge, A; Sato, Y; Watanabe, T; Yoshioka, T; Yuzawa, Y | 1 |
Afify, M; Bleilevens, C; Iwasaki, J; Klinge, U; Nagai, K; Steitz, J; Tolba, RH; Uemoto, S; Vogt, M; Weiskirchen, R; Yagi, S | 1 |
Ma, Y; Shi, X; Song, L; Yang, S; Zhao, N | 1 |
Ansah, T; Channon, KM; Charlton, C; Gangula, PR; Hale, A; Kalpana, R; Sampath, C; Srinivasan, S | 1 |
Akyuz, F; Kara, Y | 1 |
Abo El Enein, A; Al Dreny, BA; Ramadan, NM; Rashed, LA; Sabry, MM | 1 |
Chen, J; Chen, W; Chen, Z; Wang, J | 1 |
Aires, MB; Araujo, AJ; Fioretto, ET; Mota, MM; Santana-Filho, VJ; Santos, AC; Santos, MR; Souza, Kdos S | 1 |
Bozarth, MA; Pudiak, CM | 2 |
Assreuy, AM; Cavada, BS; de Alencar, NM; do Nascimento, KS; Martins, JL; Mota, MR; Rodrigues, NV | 1 |
Dehpour, AR; Ebadian, S; Ghiassy, B; Javadi-Paydar, M; Norouzi, A; Rahimi, N | 1 |
Abbolhasani, K; Nasehi, M; Piri, M; Zarrindast, MR | 1 |
Bananej, M; Piri, M; Shahab, Z; Zahmatkesh, M; Zarrindast, MR | 1 |
Bryan, RM; Crossland, RF; Lloyd, EE; Marrelli, SP; Pandit, LM | 1 |
Dunning, L; Ferrell, WR; Lockhart, JC; Mackenzie, A | 1 |
Cerf-Bensussan, N; Goudin, N; Grosos, C; Khen-Dunlop, N; Menard, S; Neunlist, M; Pousset, M; Revillon, Y; Sarnacki, S; Sauvat, F; Soret, R; Victor, A | 1 |
Bkaily, G; Brochu, I; D'Orléans-Juste, P; Desbiens, L; Gobeil, F; Houde, M; Semaan, W; Simard, E | 1 |
Benko, R; Benyó, Z; Buday, A; Hamar, P; Horvath, EM; Masszi, G; Nadasy, GL; Novak, A; Revesz, C; Ruisanchez, E; Sara, L; Tarszabo, R; Tokes, AM; Varbiro, S | 1 |
Chakraborti, A; Gulati, K; Ray, A | 1 |
Almeida, JR; Camargo, EA; de Oliveira, AP; de Oliveira, MG; de Santana, MT; De Sousa, DP; Quintans-Júnior, LJ; Santana, DG; Santana, MF | 1 |
Török, J; Zemancíková, A | 1 |
Bós, Dda S; Dillenburg, DR; Duarte, AA; Ferreira, D; Irigoyen, MC; Moraes-Silva, IC; Mostarda, C; Rigatto, K | 1 |
Abdulla, MH; Abdullah, NA; Ahmad, Fu; Chia, TY; Johns, EJ; Kaur, G; Rathore, HA; Sattar, MA | 1 |
Ding, GL; Han, LN; He, S; Liu, JW; Wang, YT; Zou, X | 1 |
Khonsung, P; Lohcharoenkal, W; Manosroi, A; Manosroi, J; Manosroi, W | 1 |
Baban, B; Brinson, KN; Crislip, GR; Elmarakby, AA; Sullivan, JC; Tipton, AJ; Yamamoto, T | 1 |
Adamo, RF; Alferiev, IS; Chorny, M; Fishbein, I; Forbes, SP; Levy, RJ | 1 |
Bhatt, DK; Gupta, S; Hay-Schmidt, A; Jansen-Olesen, I; Olesen, J; Ploug, KB; Ramachandran, R | 1 |
Asano, M; Cui, H; Du, W; Okamoto, Y; Shibamoto, T; Takuwa, N; Takuwa, Y; Yoshioka, K; Zhang, W | 1 |
Makuch, W; Mika, J; Przewlocka, B; Rojewska, E; Zychowska, M | 1 |
Kobayashi, J; Kobayashi, M; Kubo, Y; Natsume, H; Ohtake, K; Sonoda, K; Uchida, H; Uchida, M | 1 |
Belhomme, M; Buzzacott, P; Guerrero, F; Lambrechts, K; Mansourati, J; Mazur, A; Theron, M; Wang, Q | 1 |
Bavis, RW; DeAngelis, KJ; Horowitz, TC; March, RJ; Reedich, LM | 1 |
Chelluboina, B; Chetty, C; Ponnala, S; Rao, JS; Rehman, AA; Veeravalli, KK; Velpula, KK; Zakharian, E; Zhuang, T | 1 |
Kossmehl, P; Kreutz, R; Schulte, L; Schulz, A; Schütten-Faber, S; Unland, J | 1 |
Arévalo, M; Blanca, AJ; Mate, A; Miguel-Carrasco, JL; Ruiz-Armenta, MV; Vázquez, CM; Zambrano, S | 1 |
Epifano, F; Fiorito, S; Genovese, S; Kochi, T; Mori, T; Moriwaki, H; Shimizu, M; Shirakami, Y; Tanaka, T | 1 |
Tang, YH; Xiang, HY; Xu, JJ; Yang, JS | 1 |
Chavatte-Palmer, P; Dahirel, M; Gil, S; Lecarpentier, E; Morel, O; Tarrade, A; Tsatsaris, V; Zahr, N | 1 |
Kumar, A; Rinwa, P | 1 |
Bendhack, LM; Cecchini, R; da Cunha, NV; Grando, MD; Martins-Pinge, MC; Panis, C; Pernomian, L; Pinge-Filho, P; Silva, BR | 1 |
Bach, V; Canarelli, JP; Delanaud, S; Gay-Quéheillard, J; Haraux, E; Khorsi, H | 1 |
Cordeiro, RC; Costa, AM; de Lucena, DF; de Sousa, FC; Macêdo, D; Nobre Júnior, HV; Quevedo, J; Tomaz, VS; Vale, ML; Vasconcelos, SM | 1 |
Ji-Au, W; Maneesri-le Grand, S; Saengjaroentham, C; Srikiatkhachorn, A; Supornsilpchai, W | 1 |
Báez-Duarte, BG; Gonzalez-Mejia, ME; Hernández-Kelly, LC; Ortega, A; Pérez-Fuentes, R; Porchia, LM; Ruiz-Vivanco, G; Salgado, HR; Torres-Rasgado, E; Totolhua, JL | 1 |
Hasan, DM; Hashimoto, T; Kanematsu, Y; Kitazato, KT; Kudo, M; Liang, EI; Makino, H; Murakami, S; Nagahiro, S; Pena Silva, RA; Shikata, F; Shimada, K; Tada, Y; Wada, K | 1 |
Ahmadi-Dastgerdi, M; Amanlou, M; Aminizade, M; Bahremand, A; Berijani, S; Dehpour, AR; Dianati, V; Gholizadeh, R; Gooshe, M; Payandemehr, B; Rahimian, R; Sarreshte-Dari, A | 1 |
Aktuna, Z; Aydos, TR; Cinar, M; Macun, HC; Ustüner, I; Yiğit, AA; Yildirim, E | 1 |
Chen, TH; Liao, FT; Wang, JJ; Yang, YC | 2 |
Bohlender, J; Gudo, B; Nussberger, J | 1 |
Hood, SG; May, CN; Ramchandra, R | 1 |
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Guc, MO; Iskit, AB | 2 |
Hicks, C; O'Neill, MJ; Ward, M | 1 |
Adams, HR; Gupta, M; Mattox, ML; Myers, PR; Parker, JL; Rogers, S | 1 |
Cohen, RI; Genovese, J; Huberfeld, S; Scharf, SM; Steinberg, HN | 1 |
Magder, S; Vanelli, G | 1 |
Matsui, S; Matsumori, A; Okada, I; Sasayama, S; Sato, Y; Shioi, T; Shiota, K; Suzuki, H; Wang, WZ; Yamada, T | 1 |
Frohlich, ED | 1 |
Baretti, R; Buckberg, GD; Ignarro, LJ; Ma, XL; Mizuno, A; Vinten-Johansen, J; Young, HH | 1 |
Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E | 1 |
Bernátová, I; Pechánová, O; Simko, F | 1 |
Yu, L | 1 |
Kilbourn, RG; Szabó, C; Traber, DL | 1 |
Barnes, PJ; Belvisi, MG; Bernareggi, M; Mitchell, JA | 1 |
Chopin, C; Fourrier, F; Gosselin, B; Goudemand, J; Jourdain, M; Leroy, X; Mangalaboyi, J; Tournoys, A; Vallet, B | 1 |
Fouyas, IP; Kelly, PA; Ritchie, IM; Whittle, IR | 1 |
Burchardt, ER; Müller-Peddinghaus, R | 1 |
Sun, W; Wainwright, CL | 1 |
Choi, KC; Jung, M; Kang, YJ; Kim, NH; Kim, SW; Lee, JU | 1 |
Choi, KC; Kim, M; Lee, JU; Oh, HS; Yoo, K | 1 |
Macdonald, GJ; Peake, P; Pussell, BA; Wessels, J | 1 |
Maurice, T; Privat, A | 1 |
Burgert, K; Erley, CM; Heyne, N; Langanke, J; Osswald, H; Risler, T | 1 |
Abrams, GA; Dai, J; Fallon, MB; Hou, Z; Ku, DD; Luo, B | 1 |
Alcoriza, N; Bellot, JL; Blanco, A; García-Cabanes, C; Hariton, C; Orts, A; Palmero, M | 1 |
Adawi, D; Jeppsson, B; Molin, G | 1 |
Nakamura, S | 1 |
Kawaguchi, A; Matsuda, H; Miyatake, K; Nagata, S; Tamai, J; Uematsu, M | 1 |
Andhoga, M; Batten, JJ; Mathie, RT; McCarthy, ID | 1 |
Bone, HG; Booke, M; Meissner, A; Meyer, J; Prien, T; Van Aken, H; Waurick, R | 1 |
Dumont, L; Fontaine, E; Jasmin, G; Véronneau, M; Viau, S | 1 |
Nakamura, T | 1 |
Bazzani, C; Bertolini, A; Guarini, S | 1 |
Andersson, SE; Ekström, GM | 1 |
Karmeli, F; Okon, E; Rachmilewitz, D | 1 |
Opgenorth, TJ; Polakowski, JS; Pollock, DM; Wegner, CD | 1 |
Klemm, K; Moody, FG | 1 |
Evans, TW; Hellewell, PG; Liu, SF; Lu, YT; Malik, AB; Mitchell, JA | 1 |
Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-Garcia, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
Chung, JM; Sung, B; Yoon, YW | 1 |
Adachi, T; Aikawa, N; Hori, S; Inoue, S; Miyazaki, K; Nakagawa, M; Nakazawa, H; Ogawa, S; Ohnishi, Y | 1 |
Quast, MJ; Wei, J | 1 |
Inoue, T; Mashimo, T; Shibata, M; Shibuta, S; Yoshiya, I | 1 |
Feet, BA; Moen, A; Saugstad, OD; Yu, XO | 1 |
Czech, DA; Klosterman, AE; Le Sueur, KT | 1 |
Caputi, AP; Cuzzocrea, S; Zingarelli, B | 1 |
Kiehl, MG | 1 |
Dora, CD; Koch, S; Liu, S; Ruenes, G; Sanchez, A; Yezierski, RP | 1 |
Brzozowski, T; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Sliwowski, Z; Stachura, J | 1 |
Kirkeby, OJ; Rise, IR | 1 |
Bryan, RM; Cherian, L; Golding, EM; Marrelli, SP; Robertson, CS; Steenberg, ML | 1 |
Fenoy, FJ; López, E; Madrid, MI; Salom, MG; Tornel, J | 1 |
Braam, B; Koomans, HA; Turkstra, E | 1 |
Huang, WC; Tsai, RY | 1 |
Levy, D; Zochodne, DW | 1 |
Jiang, H; Liu, Y; Song, Y | 1 |
Asanuama, H; Fukunami, M; Hoki, N; Hori, M; Kitakaze, M; Koretsune, Y; Kurotobi, T; Kuzuya, T; Minamino, T; Sanada, S | 1 |
Ikeda, K; Iwasaki, Y; Kinoshita, M | 1 |
Mandarim-de-Lacerda, CA; Pereira, LM; Vianna, GM | 1 |
Wimalawansa, SJ; Yallampalli, C | 1 |
Hangai, M; Hiroi, K; Honda, Y; Mandai, M; Yoshimura, N | 1 |
De Boer, J; Meurs, H; Pouw, FM; Zaagsma, J | 1 |
Baylis, C; Zatz, R | 1 |
Dumas Hahn, M; Gomes Pessanha, M; Mandarim-de-Lacerda, CA | 1 |
Hori, M; Hoshida, S; Kawahara, K; Kuzuya, T; Yamashita, N | 1 |
Morel, N; Noël, F; Silva, CL | 1 |
Hua, TC; Moochhala, SM | 1 |
Blomquist, S; Dahm, PL; Grins, E; Mårtensson, L; Myhre, E; Thörne, J | 1 |
Gordh, T | 1 |
Wiśniewska, RJ; Wiśniewski, K | 1 |
Hoły, Z; Wiśniewski, K | 1 |
Cachofeiro, V; Lahera, V; Maeso, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
Datta, P; Javeshghani, D; Levy, RD; Magder, S; Mehta, S | 1 |
Bauters, C; Bertrand, ME; Corseaux, D; Dupuis, B; Lablanche, JM; Le Tourneau, T; Lebuffe, G; McFadden, E; Vallet, B; Van Belle, E | 1 |
Buhimschi, I; Chwalisz, K; Garfield, RE; Liao, QP; Saade, GR; Zlatnik, MG | 1 |
Kangawa, K; Kawarabayashi, T; Makino, I; Makino, Y; Shibata, K | 1 |
Deveney, AM; Jackson, DM; Johansson, C; Reif, D | 1 |
Becker, EJ; Hester, RK; Jeffrey, JS; Martinez-Lemus, LA; Odom, TW | 1 |
Cochran, JB; Cook, JA; Genovese, F; Ogura, S; Teti, G | 1 |
Clayton, RA; MacLean, MR; McGrath, JC; Nally, JE; Thomson, NC | 1 |
Buhimschi, I; Chwalisz, K; Garfield, RE; Olson, GL; Saade, GR | 1 |
Chen, K; Hirota, S; Okada, A; Wasa, M | 1 |
Baba, A; Hano, T; Kimura, K; Nishio, I; Sasajima, H; Shiotani, M; Tsuda, K | 1 |
Jadeski, LC; Lala, PK | 1 |
Cox, C; Goldstein, B; Mickelsen, D; Tipton, R; Want, A; Woolf, PD | 1 |
Ferrari, AU; Marano, G; Palazzesi, S; Vergari, A | 1 |
Anning, PB; Evans, TW; Goldstraw, P; Quinlan, GJ; Williams, EA | 1 |
Amico-Roxas, M; Caruso, A; Clementi, G; Cutuli, VM; Mangano, NG; Prato, A | 1 |
Böhmer, KP; Haas, A; Hartner, A; Hilgers, KF; Sterzel, RB; Veelken, R | 1 |
Barker, DM; Corder, R | 1 |
Batten, J; Corbett, SA; Hughes, SP; Hukkanen, M; McCarthy, ID; Polak, JM | 1 |
Andoh, T; Kuraishi, Y; Nojima, H; Tsukumo, Y; Yamaguchi, T | 1 |
Aspide, R; de Filippis, G; Fresiello, A; Gironi Carnevale, UA; Sadile, AG | 1 |
Friedrich, HJ; Klotz, KF; Roth-Isigkeit, A; Schäfer, R; Schmucker, P; Wagner, K | 1 |
Du Plooy, WJ; Hay, L; Kahler, CP; Schutte, PJ | 1 |
Abe, Y; Arakawa, Y; Itoh, K | 1 |
Hara, K; Higashi, T; Kobayashi, N; Matsuoka, H; Watanabe, S | 1 |
Kabuto, H; Mori, M; Shima, Y; Takakura, N; Tanaka, N; Yamazato, T; Yokoi, I | 1 |
Jung, O; Jung, W; Linz, W; Malinski, T; Schoelkens, BA; Wiemer, G | 1 |
da Cunha, V; Oliveira, PA; Poton, S; Pretti, SC; Rossoni, LV; Stefanon, I; Vassallo, DV | 1 |
Cahlin, C; Delbro, D; Doi, C; Gelin, J; Lönnroth, C; Lundholm, K | 1 |
de Vasconcelos, AP; Gizard, F; Marescaux, C; Nehlig, A | 1 |
Chen, C; Lokhandwala, MF; Venkatakrishnan, U | 1 |
Berber, E; Calis, A; Erbil, Y; Mercan, S | 1 |
Mandarim-de-Lacerda, CA; Meirelles Pereira, LM | 1 |
Holt, PG; Sly, PD; Tulić, MK; Wale, JL | 1 |
Schiffrin, EL | 1 |
Broadley, KJ; Toward, TJ | 1 |
Hutri-Kähönen, N; Jolma, P; Kähönen, M; Kalliovalkama, J; Kööbi, P; Pörsti, I; Tolvanen, JP; Wu, X | 1 |
Armstrong, AM; Campbell, GR; Gannon, C; Gardiner, KR; Kirk, SJ | 1 |
Howard, EF; Landon, EJ; Myers, PR; Steimle, A; Takagi, T; Tamura, M; Tanner, M | 1 |
Ea-Kim, L; Ghanam, K; Javellaud, J; Oudart, N | 1 |
Burçak, G; Inci, F; Oz, B; Seven, A; Seymen, O; Yiğit, G | 1 |
Bordet, R; Corseaux, D; Jude, B; Lund, N; Pu, Q; Robin, E; Vallet, B; Wiel, E | 1 |
Egashira, K; Kitamoto, S; Koyanagi, M; Ni, W; Shimokawa, H; Takeshita, A; Takeya, M; Yoshimura, T | 1 |
Hashizume, M; Kawanaka, H; Kishihara, F; Migou, S; Sugimachi, K; Tanoue, K; Tomikawa, M; Tsugawa, K | 1 |
Artuso, A; Bouriquet, N; Casellas, D; Moore, LC; Walcott, B | 1 |
Calhoun, DA; Chen, YF; Chestnut, DH; Connor, MG; Parks, DA; Sakawi, Y; Tarpey, M | 1 |
Bosch, J; Calatayud, S; Esplugues, JV; Hernández, C; Moreno, L; Piqué, JM; Ramírez, MC; Sanz, MJ | 1 |
Arnold, JM; Feng, Q; Hammond, JR; Lu, X; McCormack, DG; Scott, JA; Shen, J; Stathopulos, PB | 1 |
Blumberg, FC; Lorenz, C; Pfeifer, M; Riegger, GA; Sandner, P; Wolf, K | 1 |
Atucha, NM; Fortepiani, LA; García-Estañ, J; Nadal, FJ; Ortíz, MC; Ruiz-Marcos, FM | 1 |
Aoki, M; Higaki, J; Matsumoto, K; Moriguchi, A; Morishita, R; Nakamura, T; Ogihara, T; Sakonjo, H; Tomita, N | 1 |
Erley, CM; Heyne, N; Osswald, H; Risler, T; Yao, K | 1 |
Fujimura, A; Sugimoto, K; Tsuruoka, S | 1 |
Rao, VS; Santos, FA | 1 |
Bader, M; Fletcher, EC; Joshua, IG; Orolinova, N; Tahawi, Z | 1 |
Cho, CH; Li, Y; Ma, L; Wang, HY | 1 |
Chrissobolis, S; Sobey, CG | 1 |
Krismer, AC; Lindner, KH; Lingnau, W; Mueller, G; Rainer, B; Wenzel, V | 1 |
Dembo, DH | 1 |
Akishita, M; Aoki, M; Horiuchi, M; Iwai, M; Shirakami, G; Toba, K; Wu, L; Zhang, L | 1 |
Beger, HG; Kaminishi, M; Mimura, Y; Neuhaus, P; Nussler, AK; Ogawa, T; Tuzuner, E | 1 |
Göksel, HM; Karadag, O; Oztoprak, I; Taş, F; Turaçlar, U | 1 |
Cittadino, M; Coelho, OR; Coelho-Filho, OR; De Luca, IM; Hyslop, S; Moreno Júnior, H; Sampaio, RC; Tanus-Santos, JE | 1 |
Akbari, MR; Dehpour, AR; Homayounfar, H; Mani, AR; Nahavandi, A | 1 |
Inouye, S; Tanaka, J; Yamakawa, T; Yuda, Y | 1 |
Abassi, Z; Brezis, M; Goldfarb, M; Heyman, SN; Rosen, S; Shina, A | 1 |
Alonso, D; Bentura, ML; Fernández, AP; Ghiglione, M; López, JC; Martínez-Murillo, R; Richart, A; Rodrigo, J; Santacana, M; Serrano, J; Uttenthal, LO | 1 |
Honda, H; Iwata, T; Kogo, H; Mochizuki, T | 1 |
Bryan, RM; Golding, EM; Robertson, CS; You, J | 1 |
Arregui, B; Conesa, EL; Fenoy, FJ; López, B; Nadal, JC; Salom, MG; Valero, F | 1 |
Hock, CE; Liu, P; Xu, B | 1 |
Egashira, K; Inoue, S; Kataoka, C; Kitamoto, S; Koyanagi, M; Ni, W; Takeshita, A | 1 |
Arai, Y; Egashira, K; Katsuda, Y; Shimokawa, H; Tada, H; Takeshita, A; Usui, M; Yamamoto, M | 1 |
Kaneko, H; Kuwano, H; Morikawa, H; Tabata, M; Takahashi, A; Tomomasa, T; Tsuchida, Y; Watanabe, T | 1 |
Gao, H; Le, Q; Xu, Q; Zhang, J | 1 |
Deckel, AW; Freitas, R; Gary, KA; Gordinier, A; Kuwada, C; Nuttal, D; Tang, V | 1 |
Lloyd, PG; Terjung, RL; Yang, HT | 1 |
Cohen, RI; Hassell, AM; Liu, SF; Marini, C; Marzouk, K; Scharf, SM | 1 |
Balligand, JL; Dessy, C; Donckier, J; Feron, O; Havaux, X; Massart, PE; Morel, N; Piech, A; Vanoverschelde, JL | 1 |
Laughlin, MH; Ren, J; Terjung, RL; Yang, HT | 1 |
Hayakawa, H; Hirata, Y; Homma, Y; Horie, S; Kawabe, K; Kitamura, T; Minowada, S; Nagai, R; Nagata, D; Nishimatsu, H; Ohta, N; Satonaka, H; Suzuki, E; Takeuchi, T | 1 |
Chang, YS; Lee, M; Park, WS | 1 |
Ayabe, T; Chisato, N; Kasai, S; Kohgo, Y; Kono, T; Ohara, K; Taché, Y; Terano, A; Yoneda, M | 1 |
Huang, T; Lin, Y; Zhu, Y | 1 |
Barthwal, MK; Dikshit, M; Srivastava, N | 1 |
Alonso, D; Bentura, ML; Castro-Blanco, S; Encinas, JM; Fernández, AP; Fernández-Vizarra, P; Richart, A; Rodrigo, J; Rodríguez, I; Ruíz-Cabello, J; Santacana, M; Serrano, J; Uttenthal, LO | 1 |
Fujigaki, S; Maekawa, N; Saito, K; Seishima, M; Takemura, M; Wada, H; Yamada, Y | 1 |
Jover, B; Mimran, A | 1 |
Beger, HG; Kaminishi, M; Mimura, Y; Nussler, AK; Ogawa, T; Tuzuner, E | 1 |
Fuseler, J; Grisham, M; Roerig, SC; Tedesco, LS; Wolf, R | 1 |
Egashira, K; Hiasa Ki, K; Ichiki, T; Inoue, S; Ishibashi, M; Kitamoto, S; Ni, W; Shibuya, M; Takeshita, A; Usui, M; Zhao, Q | 1 |
Adler, GK; Martinez, DV; Matsumura, M; Ochoa-Maya, M; Oestreicher, E; Rocha, R; Roubsanthisuk, W; Williams, GH | 1 |
Dehpour, AR; Homayoun, H; Sayyah, M | 1 |
Baskurt, OK; Bor-Kucukatay, M; Hacioglu, G; Ozkaya, G; Yalcin, O | 1 |
Holtz, J; Jäger, D; Müller, SP; Müller-Werdan, U; Pönicke, K; Werdan, K | 1 |
Belosjorow, S; Büchert, A; Dörge, H; Heusch, G; Konietzka, I; Krüger, A; Martin, C; Schulz, R; Schwanke, U; Thielmann, M; van De Sand, A | 1 |
Ishimura, N; Nakaya, Y; Takahashi, A; Takishita, E | 1 |
Jinyong, W; Ruiping, X; Weidong, S; Xiaolong, W | 1 |
Cobben, DC; Deutz, NE; Hallemeesch, MM; Soeters, PB | 1 |
Durie, M; Levy, BI; Silvestre, JS; Tamarat, R | 1 |
Boulu, RG; Buisson, A; Plotkine, M | 1 |
Dawson, DA; Graham, DI; Kusumoto, K; Macrae, IM; McCulloch, J | 1 |
19 review(s) available for ng-nitroarginine methyl ester and Disease Models, Animal
Article | Year |
---|---|
[INVOLVEMENT OF NITRIC OXIDE CYNTHASE IN THE EARLY PHASE OF THE HEART ISCHEMIC PRECONDITIONING].
Topics: Animals; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitrites | 2016 |
The Role of Nitric Oxide Synthase Inhibitors in Schizophrenia.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Humans; Ketamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phencyclidine; Schizophrenia | 2016 |
Participation of nitric oxide in different models of experimental hypertension.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Hypertension; Hypertriglyceridemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Wistar; Sodium Chloride, Dietary; Stress, Psychological; Sympathetic Nervous System | 2008 |
Protective importance of the myogenic response in the renal circulation.
Topics: Animals; Disease Models, Animal; Female; Glomerular Filtration Rate; Homeostasis; Hypertension; Male; Nephrosclerosis; NG-Nitroarginine Methyl Ester; Primary Prevention; Proteinuria; Random Allocation; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renal Circulation; Sensitivity and Specificity; Vascular Patency | 2009 |
[Elements for the effective evaluation of natural products with possible antihypertensive effects].
Topics: Animals; Antihypertensive Agents; Aorta; Biological Products; Blood Pressure; Disease Models, Animal; Drug Evaluation, Preclinical; Hypertension; Medicine, Traditional; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Phytotherapy; Plant Preparations; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Renin-Angiotensin System; Vascular Resistance; Vasodilator Agents; Ventricular Remodeling | 2009 |
Animal models for the study of arterial hypertension.
Topics: Animals; Denervation; Diet; Disease Models, Animal; Humans; Hypertension; Hypertension, Renal; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pressoreceptors; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Transgenic | 2011 |
Translational neuropharmacology: the use of human isolated gastrointestinal tissues.
Topics: Aged; Animals; Disease Models, Animal; Electric Stimulation; Female; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; In Vitro Techniques; Individuality; Intestine, Small; Male; Models, Biological; Motilin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons; Neuropharmacology; NG-Nitroarginine Methyl Ester; Peristalsis; Receptors, Serotonin; Research Design; Species Specificity; Synaptic Transmission; Translational Research, Biomedical | 2013 |
Role of sensory nervous system vasoactive peptides in hypertension.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Cells, Cultured; Desoxycorticosterone; Disease Models, Animal; Female; Hypertension; Mice; Mice, Knockout; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Pregnancy; Rats; Rats, Inbred SHR; Sensory Receptor Cells; Substance P | 2002 |
Assessment of anticolitic drugs in the trinitrobenzene sulfonic acid (TNBS) rat model of inflammatory bowel disease.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arginine; Blotting, Western; Colitis; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Inflammatory Bowel Diseases; Injections, Subcutaneous; Instillation, Drug; Male; Models, Animal; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2003 |
Ageing, hypertension and the kidney: new data on an old problem.
Topics: Age Factors; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Calcium; Disease Models, Animal; Humans; Kidney; Kidney Failure, Chronic; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR | 2003 |
Nitric oxide and tubulointerstitial nephritides.
Topics: Animals; Biomarkers; Chronic Disease; Disease Models, Animal; Humans; Hypertension; Mice; Mice, Transgenic; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prognosis; Severity of Illness Index | 2004 |
Angiotensin II--nitric oxide interactions in the control of sympathetic outflow in heart failure.
Topics: Angiotensin II; Animals; Baroreflex; Cardiac Output, Low; Disease Models, Animal; Excitatory Postsynaptic Potentials; Exercise; Heart Failure; Hemodynamics; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Risk Factors; Sensitivity and Specificity; Sympathetic Nervous System | 2000 |
[Hypertensive organ injuries in spontaneously hypertensive rats given N(G)-nitro-L-arginine methyl ester].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiovascular System; Disease Models, Animal; Hypertension; Kidney; Life Style; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Risk Factors | 2006 |
Analogy of cardiac and renal complications in essential hypertension and aged SHR or L-NAME/SHR.
Topics: Aging; Animals; Antihypertensive Agents; Disease Models, Animal; Enzyme Inhibitors; Heart Diseases; Hypertension; Kidney Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR | 2007 |
Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: lessons learned from experimental and clinical studies.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Dogs; Drug Therapy, Combination; Enzyme Inhibitors; Free Radical Scavengers; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Rats; Rodentia; Shock, Septic | 1997 |
Chronic nitric oxide inhibition model six years on.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Heart; Hemodynamics; Humans; Hypertension, Renovascular; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 1998 |
Endothelin: role in experimental hypertension.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Fructose; Hypertension; Insulin Resistance; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Dahl; Rats, Inbred SHR | 2000 |
Nitric oxide and cardiopulmonary resuscitation.
Topics: Animals; Cardiopulmonary Resuscitation; Coronary Circulation; Disease Models, Animal; Heart Arrest; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Swine; Vasodilator Agents | 2001 |
Nitric oxide inhibition and renal alterations.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Humans; Kidney; Kidney Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
4 trial(s) available for ng-nitroarginine methyl ester and Disease Models, Animal
Article | Year |
---|---|
Cilostazol decreases duration of spreading depolarization and spreading ischemia after aneurysmal subarachnoid hemorrhage.
Topics: Aged; Animals; Brain Ischemia; Cerebrovascular Circulation; Cilostazol; Cortical Spreading Depression; Disease Models, Animal; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Male; Middle Aged; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Potassium Chloride; Rats; Rats, Sprague-Dawley; Retrospective Studies; Subarachnoid Hemorrhage | 2018 |
Nitric oxide mediates the beneficial effect of chronic naltrexone on cholestasis-induced memory impairment in male rats.
Topics: Animals; Cholestasis; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Guanidines; Ligation; Male; Maze Learning; Memory Disorders; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Space Perception; Time Factors | 2013 |
Decrease in sensitisation rate and intestinal anaphylactic response after nitric oxide synthase inhibition in a food hypersensitivity model.
Topics: Animals; Arginine; Colon; Disease Models, Animal; Guinea Pigs; Immunization; Immunoglobulin A; Immunoglobulin E; Intestinal Mucosa; Lactoglobulins; Male; Milk; Milk Hypersensitivity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Permeability | 1996 |
Pulmonary arterial pressure and electrocardiograms in broiler chickens infused intravenously with L-NAME, an inhibitor of nitric oxide synthase, or sodium nitroprusside (SNP), a nitric oxide donor.
Topics: Animals; Chickens; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; Hypertension, Pulmonary; Injections, Intravenous; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Pulmonary Wedge Pressure; Vascular Resistance; Vasoconstriction | 2002 |
966 other study(ies) available for ng-nitroarginine methyl ester and Disease Models, Animal
Article | Year |
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Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Modulation by antenatal therapies of cardiovascular and renal programming in male and female offspring of preeclamptic rats.
Topics: Animals; Atrasentan; Cardiovascular Diseases; Disease Models, Animal; Endothelin A Receptor Antagonists; Female; Kidney Diseases; Male; Methyldopa; Naphthalenes; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Prenatal Care; Propionates; Rats; Receptors, Thromboxane A2, Prostaglandin H2; Sex Factors; Sympatholytics | 2021 |
Short-lived sensitization of cardiovascular outcomes of postpartum endotoxemia in preeclamptic rats: Role of medullary solitary tract neuroinflammation.
Topics: Animals; Disease Models, Animal; Endotoxemia; Female; Humans; Lipopolysaccharides; Male; Neuroinflammatory Diseases; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Puerperal Infection; Rats; Solitary Nucleus | 2021 |
Anti-inflammatory and Antioxidant Effects of Pyrroloquinoline Quinone in L-NAME-Induced Preeclampsia-Like Rat Model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Female; Injections, Intraperitoneal; NG-Nitroarginine Methyl Ester; Oxidative Stress; PQQ Cofactor; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley | 2022 |
Astaxanthin engages the l-arginine/NO/cGMP/KATP channel signaling pathway toward antinociceptive effects.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Glyburide; KATP Channels; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Signal Transduction; Sildenafil Citrate; Xanthophylls | 2021 |
Synergistic effect between quinpirole and L-NAME as well as sulpiride and L-arginine on the modulation of anxiety and memory processes in the 6-OHDA mouse model of Parkinson's disease: An isobologram analysis.
Topics: Adrenergic Agents; Animals; Anxiety; Arginine; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Therapy, Combination; Enzyme Inhibitors; Male; Memory; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidopamine; Parkinson Disease; Quinpirole; Receptors, Dopamine D2; Sulpiride | 2021 |
Maternal vitamin D deficiency reduces docosahexaenoic acid, placental growth factor and peroxisome proliferator activated receptor gamma levels in the pup brain in a rat model of preeclampsia.
Topics: Animals; Brain; Case-Control Studies; Disease Models, Animal; Docosahexaenoic Acids; Female; Maternal-Fetal Exchange; NG-Nitroarginine Methyl Ester; Placenta; Placenta Growth Factor; PPAR gamma; Pre-Eclampsia; Pregnancy; Rats; Vitamin D; Vitamin D Deficiency | 2021 |
Evaluation of Oxidative Stress Biomarkers, Pro-Inflammatory Cytokines, and Histological Changes in Experimental Hypertension, Dyslipidemia, and Type 1 Diabetes Mellitus.
Topics: Animals; Biomarkers; Cytokines; Diabetes Mellitus, Type 1; Diet, High-Fat; Disease Models, Animal; Dyslipidemias; Hypertension; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Streptozocin; Sulfhydryl Compounds | 2022 |
Preeclampsia associated changes in volume density of fetoplacental vessels in Chinese women and mouse model of preeclampsia.
Topics: Angiogenesis Inducing Agents; Animals; China; Disease Models, Animal; Female; Humans; Mice; NG-Nitroarginine Methyl Ester; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Vascular Endothelial Growth Factor Receptor-1 | 2022 |
Combination of Endothelin-1 (ET-1) and L-NAME to Induce Murine Focal Cortical Stroke with Persistent Sensorimotor Deficits.
Topics: Animals; Disease Models, Animal; Endothelin-1; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Rats; Stroke; Vasoconstrictor Agents | 2022 |
Evaluation of the Effect of the Fibroblast Growth Factor Type 2 (FGF-2) Administration on Placental Gene Expression in a Murine Model of Preeclampsia Induced by L-NAME.
Topics: Animals; Disease Models, Animal; Female; Fibroblast Growth Factor 2; Gene Expression; Humans; NG-Nitroarginine Methyl Ester; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Superoxide Dismutase-1; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2022 |
Saluisn-β contributes to endothelial dysfunction in monocrotaline-induced pulmonary arterial hypertensive rats.
Topics: Acetylcholine; Animals; Antioxidants; Disease Models, Animal; Hypertension; Hypertension, Pulmonary; Immunoglobulin G; Monocrotaline; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2022 |
Attenuated effect of zinc gluconate on oxidative stress, inflammation, and angiogenic imbalance in pre-eclampsia rats.
Topics: Animals; Disease Models, Animal; Female; Humans; Inflammation; NG-Nitroarginine Methyl Ester; Oxidative Stress; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Zinc | 2022 |
The L-NAME mouse model of preeclampsia and impact to long-term maternal cardiovascular health.
Topics: Animals; C-Reactive Protein; Cardiovascular Diseases; Disease Models, Animal; Endothelin-1; Female; Matrix Metalloproteinase 9; Mice; NG-Nitroarginine Methyl Ester; Phenylephrine; Placenta; Pre-Eclampsia; Pregnancy; RNA, Messenger; Vascular Endothelial Growth Factor Receptor-1; Vasoconstrictor Agents | 2022 |
Possible Interaction of Opioidergic and Nitrergic Pathways in the Anticonvulsant Effect of Ivermectin on Pentylenetetrazole-Induced Clonic Seizures in Mice.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Ivermectin; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures | 2023 |
Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a "2-Hit" Murine Model.
Topics: Animals; Disease Models, Animal; Drinking Water; Heart Failure; Hydralazine; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Sodium Nitrite; Stroke Volume | 2023 |
The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes.
Topics: Angiogenesis Inhibitors; Animals; Caspases; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Humans; NG-Nitroarginine Methyl Ester; Podocytes; Proteinuria; Rats | 2023 |
Efficacy of a growth hormone-releasing hormone agonist in a murine model of cardiometabolic heart failure with preserved ejection fraction.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Growth Hormone-Releasing Hormone; Heart Failure; Inflammation; Mice; NG-Nitroarginine Methyl Ester; Stroke Volume; Vascular Endothelial Growth Factor A; Ventricular Function, Left | 2023 |
Influence of Remote Ischemic Conditioning and Nitrogen Monoxide on Angiogenesis and Microcirculation in a Mouse Ear Burn Model.
Topics: Animals; Burns; Disease Models, Animal; Edema; Ischemia; Mice; Microcirculation; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Skin | 2024 |
Involvement of l-arginine-nitric oxide pathway in the antidepressant and memory promoting effects of morin in mice.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Depression; Disease Models, Animal; Flavonoids; Injections, Intraperitoneal; Male; Memory; Memory and Learning Tests; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Signal Transduction; Swimming | 2019 |
Evaluation of a rat model of functional urinary bladder outlet obstruction produced by chronic inhibition of nitric oxide synthase.
Topics: Animals; Disease Models, Animal; Female; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Urethra; Urinary Bladder; Urinary Bladder Neck Obstruction | 2019 |
Vitexin ameliorates preeclampsia phenotypes by inhibiting TFPI-2 and HIF-1α/VEGF in a l-NAME induced rat model.
Topics: Animals; Apigenin; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Female; Glycoproteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; NG-Nitroarginine Methyl Ester; Phenotype; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Endothelial Growth Factor A | 2019 |
The Effects of Irisin on Nω-Nitro-L-arginine Methyl Ester Hydrochloride-Induced Hypertension in Rats
Topics: Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Fibronectins; Hypertension; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats; Rats, Sprague-Dawley; Turkey | 2019 |
Virgin rice bran oil alleviates hypertension through the upregulation of eNOS and reduction of oxidative stress and inflammation in L-NAME-induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Disease Models, Animal; Hypertension; Inflammation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rice Bran Oil; Up-Regulation | 2020 |
Vaccine Targeted Alpha 1D-Adrenergic Receptor for Hypertension.
Topics: Animals; Biopsy, Needle; China; Disease Models, Animal; Down-Regulation; Hypertension; Immunohistochemistry; Kidney Function Tests; Male; Molecular Targeted Therapy; NG-Nitroarginine Methyl Ester; Random Allocation; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vaccines | 2019 |
Central EP3 (E Prostanoid 3) Receptors Mediate Salt-Sensitive Hypertension and Immune Activation.
Topics: Adaptive Immunity; Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Brain; Dinoprostone; Disease Models, Animal; Female; Flow Cytometry; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Random Allocation; Real-Time Polymerase Chain Reaction; Receptors, Prostaglandin E, EP3 Subtype; Sodium, Dietary | 2019 |
Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction.
Topics: Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose Intolerance; Heart Failure; Humans; Hypertension; Male; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Risk Factors; Sex Characteristics; Sex Factors; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling; Weight Gain | 2019 |
Renin angiotensin system molecules and nitric oxide local interactions in the adrenal gland of Trypanosoma cruzi infected rats.
Topics: Adrenal Glands; Animals; Chagas Disease; Disease Models, Animal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Trypanosoma cruzi | 2020 |
Interference with AGEs formation and AGEs-induced vascular injury mediates curcumin vascular protection in metabolic syndrome.
Topics: Animals; Aorta; Curcumin; Disease Models, Animal; Endothelium, Vascular; Free Radical Scavengers; Glycation End Products, Advanced; Male; Metabolic Syndrome; NG-Nitroarginine Methyl Ester; Pyruvaldehyde; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2020 |
Involvement of NO in Antinociception of NSAIDS in Murine Formalin Hind Paw Assay.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Formaldehyde; Humans; Indazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nociception; Nociceptors; Pain; Pain Measurement | 2020 |
Tangeretin mitigates l-NAME-induced ventricular dysfunction and remodeling through the AT
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Flavones; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventricular Dysfunction, Left | 2020 |
Head-to-head comparison of inorganic nitrate and metformin in a mouse model of cardiometabolic disease.
Topics: Administration, Oral; Animals; Cardiovascular Diseases; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; Male; Metformin; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase | 2020 |
Unfolding Discoveries in Heart Failure.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Endoribonucleases; Heart Failure; Heart Failure, Diastolic; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrosative Stress; Stroke Volume | 2020 |
Effects of NO/cGMP inhibitors in a rat model of anaphylactoid shock.
Topics: Anaphylaxis; Animals; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Indigo Carmine; Male; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar | 2020 |
Macrophage neuronal nitric oxide synthase (NOS1) controls the inflammatory response and foam cell formation in atherosclerosis.
Topics: Animals; Atherosclerosis; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Disease Progression; Foam Cells; Humans; Inflammation; Lipoproteins, LDL; Macrophages; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I | 2020 |
Anti-lipidemic Effect of Fractions of Peristrophe bivalvis Leaf in NG-nitro-L-arginine Methyl Ester (L-NAME) Treated Rats.
Topics: Acanthaceae; Animals; Atherosclerosis; Blood Cell Count; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Disease Models, Animal; Humans; Hypertension; Hypolipidemic Agents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Triglycerides | 2020 |
Antihypertensive effect of Phragmanthera incana (Schum) Balle on NG-nitro-L-Arginine methyl ester (L-NAME) induced hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Arterial Pressure; Biomarkers; Captopril; Disease Models, Animal; Hypertension; Interleukin-6; Kidney; Lipid Peroxidation; Liver; Loranthaceae; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitrites; Oxidative Stress; Plant Extracts; Rats, Wistar; Tumor Necrosis Factor-alpha | 2020 |
Electrical stimulation of the carotid sinus lowers arterial pressure and improves heart rate variability in L-NAME hypertensive conscious rats.
Topics: Animals; Arterial Pressure; Baroreflex; Disease Models, Animal; Electric Stimulation Therapy; Heart Rate; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats, Wistar | 2020 |
Exploring the beneficial effects and possible mechanisms of repeated episodes of whole-body hypoxic perconditioning in rat model of preeclampsia.
Topics: Animals; Disease Models, Animal; Female; Hypoxia; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats | 2020 |
Effects of oxidative stress on liver, brain and spinal cord of rats using L-NAME and treated with hydroxyurea. A model of sickle cell complication.
Topics: Anemia, Sickle Cell; Animals; Brain; Disease Models, Animal; Hydroxyurea; Liver; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats; Rats, Wistar; Spinal Cord | 2020 |
Melatonin attenuates hypertension and oxidative stress in a rat model of L-NAME-induced gestational hypertension.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Hypertension, Pregnancy-Induced; Melatonin; NF-E2-Related Factor 2; NG-Nitroarginine Methyl Ester; Oxidative Stress; Placenta; Placenta Growth Factor; Pregnancy; Proteinuria; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor Receptor-1 | 2020 |
Acetylcholinesterase inhibition prevents alterations in cardiovascular autonomic control and gastric motility in L-NAME-induced hypertensive rats.
Topics: Acetylcholinesterase; Animals; Arterial Pressure; Autonomic Nervous System; Baroreflex; Cardiovascular System; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Protective Agents; Pyridostigmine Bromide; Rats; Rats, Wistar; Stomach; Stroke Volume | 2020 |
Nitric oxide synthase mediates cerebellar dysfunction in mice exposed to repetitive blast-induced mild traumatic brain injury.
Topics: Animals; Blast Injuries; Blood-Brain Barrier; Brain Concussion; Cerebellar Diseases; Cerebellum; Disease Models, Animal; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Purkinje Cells | 2020 |
Disparate Effect of Antioxidant Supplements on the Basal Tone and Vascular Remodeling of the Aorta in Hypertensive Rats.
Topics: Animals; Antioxidants; Aorta, Thoracic; Ascorbic Acid; Cyclic N-Oxides; Dietary Supplements; Disease Models, Animal; Glutathione; Hypertension; Male; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Rats, Sprague-Dawley; Spin Labels; Vascular Remodeling; Vasoconstriction | 2020 |
Affective dimensions of pain and region -specific involvement of nitric oxide in the development of empathic hyperalgesia.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Empathy; Female; Hyperalgesia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociception; Pain; Rats, Wistar | 2020 |
Antihypertensive and vasoprotective effects of Clausena lansium fruits extract in L-NAME induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Clausena; Disease Models, Animal; Fruit; Glutathione; Hypertension; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxides | 2020 |
The Role of Losartan as a Potential Neuroregenerative Pharmacological Agent after Aneurysmal Subarachnoid Haemorrhage.
Topics: Animals; Basilar Artery; Disease Models, Animal; Endothelin-1; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Regenerative Medicine; Subarachnoid Hemorrhage; Vasoconstriction; Vasodilation; Vasodilator Agents; Vasospasm, Intracranial | 2020 |
Vasorelaxant and Antihypertensive Effects of Mentha pulegium L. in Rats: An In vitro and In vivo Approach.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; Calcium Channel Blockers; Calcium Signaling; Disease Models, Animal; Hypertension; Male; Mentha pulegium; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats, Wistar; Vasodilation; Vasodilator Agents | 2021 |
Erythropoietin Mimetic Peptide (pHBSP) Corrects Endothelial Dysfunction in a Rat Model of Preeclampsia.
Topics: Animals; bcl-2-Associated X Protein; Blood Pressure; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Erythropoietin; Female; Microcirculation; NG-Nitroarginine Methyl Ester; Oligopeptides; Placenta; Pre-Eclampsia; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2020 |
Pentadecapeptide BPC 157 counteracts L-NAME-induced catalepsy. BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat acute and chronic models resembling 'positive-like' symptoms of schizophrenia.
Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Enzyme Inhibitors; Haloperidol; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Proteins; Rats; Rats, Wistar; Schizophrenia | 2021 |
Hypotensive and antihypertensive effects of an aqueous extract from Guinep fruit (Melicoccus bijugatus Jacq) in rats.
Topics: Animals; Antihypertensive Agents; Desoxycorticosterone Acetate; Disease Models, Animal; Endothelium, Vascular; Heart Rate; Hypotension; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Sapindaceae; Vasodilation | 2020 |
The Possible Regulatory Mechanisms of Aqueous, Ethyl Acetate and NHexane Fractions of the Ribes khorassanicum Extract on Acute Hypertension in Rats.
Topics: Acetates; Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Disease Models, Animal; Hexanes; Hypertension; Losartan; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Rats, Wistar; Ribes; Signal Transduction; Water | 2021 |
Prenatal vitamin D supplementation reduces blood pressure and improves placental angiogenesis in an animal model of preeclampsia.
Topics: Animals; Blood Pressure; Calcifediol; Dietary Supplements; Disease Models, Animal; Eating; Female; Gene Expression; NG-Nitroarginine Methyl Ester; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Transcription Factors; Vascular Endothelial Growth Factor Receptor-1; Vitamin D; Vitamin D Deficiency | 2020 |
Caffeic acid attenuates gastric mucosal damage induced by ethanol in rats via nitric oxide modulation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Caffeic Acids; Cholinergic Agents; Disease Models, Animal; Ethanol; Gastric Mucosa; Glutathione; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2021 |
A Blunted Sympathetic Function and an Enhanced Nitrergic Activity Contribute to Reduce Mesenteric Resistance in Hyperthyroidism.
Topics: Adipose Tissue; Animals; Body Weight; Disease Models, Animal; Electric Stimulation; Humans; Hyperthyroidism; Mesenteric Arteries; Mesenteric Veins; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Thyroxine; Vasoconstriction | 2021 |
Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway.
Topics: Animals; Cardiomyopathies; Cardiotoxicity; Disease Models, Animal; Doxorubicin; Endothelial Progenitor Cells; Endothelium; Fenofibrate; Heart Failure; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Signal Transduction; Vascular Endothelial Growth Factor A | 2021 |
ELABELA alleviates syncytiotrophoblast hypoxia/reoxygenation injury and preeclampsia-like symptoms in mice by reducing apoptosis.
Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Female; Humans; Hypoxia; Mice; NG-Nitroarginine Methyl Ester; Peptide Hormones; Placenta; Pre-Eclampsia; Pregnancy; Trophoblasts | 2021 |
Inhibition of L-NAME-induced hypertension by combined treatment with apocynin and catalase: the role of Nox 4 expression.
Topics: Acetophenones; Animals; Antioxidants; Catalase; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; NADPH Oxidase 4; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred WKY; Reactive Oxygen Species | 2021 |
CRIP1 expression in monocytes related to hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Cell Differentiation; Cohort Studies; Disease Models, Animal; Humans; Hypertension; Macrophages; Male; Monocytes; NG-Nitroarginine Methyl Ester; Spleen; Transcriptome | 2021 |
Effects of garden cress, fenugreek and black seed on the pharmacodynamics of metoprolol: an herb-drug interaction study in rats with hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP2D6; Disease Models, Animal; Heart Rate; Herb-Drug Interactions; Hypertension; Lepidium sativum; Metoprolol; NG-Nitroarginine Methyl Ester; Nigella sativa; Rats; Rats, Wistar; Trigonella | 2021 |
Renoprotective and therapeutic effects of newly water, ethanol, and butanol ginseng fractions in hypertensive and chronic kidney disease with L-NAME.
Topics: Animals; Butanols; Disease Models, Animal; Ethanol; Female; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Hypertension; Losartan; NG-Nitroarginine Methyl Ester; Panax; Plant Extracts; Rats; Renal Insufficiency, Chronic; Tumor Necrosis Factor-alpha; Water | 2021 |
CXCR4 signaling in macrophages contributes to periodontal mechanical hypersensitivity in Porphyromonas gingivalis-induced periodontitis in mice.
Topics: Animals; Antibodies; Antigens, Differentiation; Bacteroidaceae Infections; Disease Models, Animal; Hyperalgesia; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Pain Measurement; Periodontitis; Porphyromonas gingivalis; Receptors, CXCR4; Signal Transduction; Statistics, Nonparametric | 2017 |
Negligible effect of eNOS palmitoylation on fatty acid regulation of contraction in ventricular myocytes from healthy and hypertensive rats.
Topics: Animals; Arginine; Disease Models, Animal; Fatty Acids; Heart Ventricles; Hypertension; Male; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxygen Consumption; Palmitic Acid; Rats; Rats, Sprague-Dawley | 2017 |
Celecoxib aggravates cardiac apoptosis in L-NAME-induced pressure overload model in rats: Immunohistochemical determination of cardiac caspase-3, Mcl-1, Bax and Bcl-2.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Cardiomegaly; Caspase 3; Celecoxib; Creatine Kinase, MB Form; Disease Models, Animal; DNA Fragmentation; L-Lactate Dehydrogenase; Male; Myeloid Cell Leukemia Sequence 1 Protein; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2017 |
Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability.
Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Blood Pressure Determination; Carbazoles; Carvedilol; Collagen; Disease Models, Animal; Fibrosis; Heart Ventricles; Humans; Hypertension; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NG-Nitroarginine Methyl Ester; Propanolamines; Rats; Rats, Wistar; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2017 |
Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril.
Topics: Acetylcysteine; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension; Light; Male; Melatonin; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Ventricular Remodeling | 2017 |
Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME.
Topics: Animals; Anti-Ulcer Agents; Antidotes; Arginine; Brain; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Proteins; Rats; Rats, Wistar; Stomach; Stomach Ulcer | 2017 |
Exercise training with concomitant nitric oxide synthase inhibition improved anxiogenic behavior, spatial cognition, and BDNF/P70S6 kinase activation in 20-month-old rats.
Topics: Age Factors; Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Caspase 3; Cognition; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exercise Therapy; Hippocampus; Male; Maze Learning; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Prefrontal Cortex; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa; Running; Signal Transduction; Spatial Memory | 2018 |
Role of ghrelin in small intestinal motility following pediatric intracerebral hemorrhage in mice.
Topics: Animals; Atropine; Cerebral Hemorrhage; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Gastrointestinal Motility; Ghrelin; Ileum; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Propranolol; RNA, Messenger | 2017 |
Icariin improves acute kidney injury and proteinuria in a rat model of pregnancy‑induced hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Down-Regulation; Female; Flavonoids; Gestational Age; Hypertension, Pregnancy-Induced; Kidney; Membrane Proteins; NG-Nitroarginine Methyl Ester; Pregnancy; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; Reproduction; Up-Regulation | 2017 |
Genetic Deletion of the NOS3 Gene in CAV1-/- Mice Restores Aqueous Humor Outflow Function.
Topics: Animals; Aqueous Humor; Caveolin 1; Disease Models, Animal; Enzyme Inhibitors; Gene Deletion; Intraocular Pressure; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroprusside | 2017 |
Angiotensin-converting enzyme 2 activation ameliorates pulmonary endothelial dysfunction in rats with pulmonary arterial hypertension through mediating phosphorylation of endothelial nitric oxide synthase.
Topics: Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Endothelium, Vascular; Enzyme Activators; Humans; Hypertension, Pulmonary; Imidazoles; Leucine; Lung; Male; Monocrotaline; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Phosphorylation; Pulmonary Artery; Pyrans; Rats; Rats, Sprague-Dawley; Signal Transduction; Specific Pathogen-Free Organisms; Spiro Compounds; Xanthenes | 2017 |
Modulation of the anticonvulsant effect of swim stress by agmatine.
Topics: Agmatine; Analgesics, Opioid; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction; Swimming | 2018 |
A Reliable Mouse Model of Hind limb Gangrene.
Topics: Animals; Blood Flow Velocity; Disease Models, Animal; Femoral Artery; Gangrene; Hindlimb; Ischemia; Ligation; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peripheral Arterial Disease; Regional Blood Flow; Species Specificity; Time Factors | 2018 |
Chrysophyllum cainito (apple-star): a fruit with gastroprotective activity in experimental ulcer models.
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Ethanol; Female; Fruit; Gastric Mucosa; Indomethacin; Mice; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Extracts; Plant Leaves; Sapotaceae; Stomach Ulcer | 2019 |
Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
Topics: Animals; Cerebrovascular Circulation; Cognition Disorders; Cyclooxygenase Inhibitors; Disease Models, Animal; Gait; Indomethacin; Lameness, Animal; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurovascular Coupling; NG-Nitroarginine Methyl Ester; Random Allocation; Sensitivity and Specificity | 2017 |
Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease.
Topics: Animals; Atropine; Benzazepines; Brain; Carbachol; Cytokines; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Evoked Potentials; Face; Gastrointestinal Motility; Gene Expression Regulation; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Lesch-Nyhan Syndrome; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Reactive Oxygen Species; Tyrosine 3-Monooxygenase | 2018 |
Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights.
Topics: Animals; Anti-Ulcer Agents; Arginine; Colitis; Collateral Circulation; Colon; Disease Models, Animal; Humans; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Peptide Fragments; Proteins; Rats; Rats, Wistar; Reperfusion Injury | 2017 |
Agmatine co-treatment attenuates allodynia and structural abnormalities in cisplatin-induced neuropathy in rats.
Topics: Agmatine; Analgesics; Animals; Animals, Newborn; Behavior, Animal; Cells, Cultured; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ganglia, Spinal; Hyperalgesia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peripheral Nervous System Diseases; Primary Cell Culture; Rats, Sprague-Dawley; Sciatic Nerve | 2018 |
Apelin/APJ expression in the heart and kidneys of hypertensive rats.
Topics: Animals; Apelin; Apelin Receptors; Blotting, Western; Body Weight; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Hypertension; Immunohistochemistry; Kidney; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Reference Standards | 2018 |
Different Effects of Pravastatin on Preeclampsia-like Symptoms in Different Mouse Models.
Topics: Animals; Arterial Pressure; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Pravastatin; Pre-Eclampsia; Pregnancy | 2018 |
Venlafaxine prevents morphine antinociceptive tolerance: The role of neuroinflammation and the l-arginine-nitric oxide pathway.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Brain; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione Peroxidase; Lipid Peroxidation; Male; Mice; Morphine; Morphine Dependence; NG-Nitroarginine Methyl Ester; Nitrites; Oxidative Stress; Pain Measurement; Signal Transduction; Venlafaxine Hydrochloride | 2018 |
Glomerular hyperpermeability after acute unilateral ureteral obstruction: effects of Tempol, NOS, RhoA, and Rac-1 inhibition.
Topics: Amides; Aminoquinolines; Animals; Antioxidants; Arterial Pressure; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Heart Rate; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Proteinuria; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats, Sprague-Dawley; Reactive Oxygen Species; rho GTP-Binding Proteins; rho-Associated Kinases; Spin Labels; Time Factors; Ureteral Obstruction | 2018 |
Evidence of a role for spinal HMGB1 in ischemic stress-induced mechanical allodynia in mice.
Topics: Animals; Antibodies, Monoclonal; Brain Ischemia; Calcium-Binding Proteins; Disease Models, Animal; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; HMGB1 Protein; Hyperalgesia; Lipopolysaccharides; Male; Mice; Microfilament Proteins; Neuroglia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphopyruvate Hydratase; Physical Stimulation; Receptor for Advanced Glycation End Products; Spinal Cord; Toll-Like Receptor 4 | 2018 |
Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway.
Topics: Animals; Brain Ischemia; Cerebral Arteries; Chromones; Cyclic GMP; Disease Models, Animal; Diterpenes, Clerodane; Male; Morpholines; Naltrexone; NG-Nitroarginine Methyl Ester; Phosphatidylinositol 3-Kinases; Pia Mater; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Role of AKR1C3 in renal injury and glibenclamide is anti-inflammatory in preeclamptic rats.
Topics: Acute Kidney Injury; Aldo-Keto Reductase Family 1 Member C3; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Female; Glyburide; Microscopy, Electron, Transmission; Multienzyme Complexes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Reactive Oxygen Species | 2018 |
Magnesium sulfate versus esomeprazole impact on the neonates of preeclamptic rats.
Topics: Animals; Animals, Newborn; Birth Weight; Blood Pressure; Disease Models, Animal; Esomeprazole; Female; Fetal Weight; Litter Size; Magnesium Sulfate; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley | 2018 |
Dietary supplementation of tiger nut alters biochemical parameters relevant to erectile function in l-NAME treated rats.
Topics: Acetylcholinesterase; Adenosine Deaminase; Animal Feed; Animals; Arginase; Brain; Cyperus; Dietary Supplements; Disease Models, Animal; Erectile Dysfunction; GPI-Linked Proteins; Male; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penile Erection; Penis; Plant Extracts; Plant Tubers; Quercetin; Rats, Wistar | 2018 |
Fasudil hydrochloride ameliorates memory deficits in rat model of streptozotocin-induced Alzheimer's disease: Involvement of PI3-kinase, eNOS and NFκB.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alzheimer Disease; Animals; Disease Models, Animal; Enzyme Inhibitors; Memory Disorders; Neuroprotective Agents; NF-kappa B; NG-Nitroarginine Methyl Ester; Nootropic Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats, Wistar; Streptozocin; Wortmannin | 2018 |
Int6/eIF3e Silencing Promotes Placenta Angiogenesis in a Rat Model of Pre-eclampsia.
Topics: Animals; Blood Pressure; Disease Models, Animal; Eukaryotic Initiation Factor-3; Female; Humans; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Rats, Sprague-Dawley; RNA Interference | 2018 |
Effect of co-administration of two different phosphodiesterase inhibitors and a β
Topics: Adrenergic beta-3 Receptor Agonists; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Ethanolamines; Humans; Male; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Rolipram; Tadalafil; Treatment Outcome; Urinary Bladder; Urinary Bladder, Overactive | 2018 |
Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats.
Topics: AMP-Activated Protein Kinases; Animals; Colon; Disease Models, Animal; Domperidone; Dopamine Antagonists; Evans Blue; Hyperalgesia; Hypoglycemic Agents; Intestinal Mucosa; Irritable Bowel Syndrome; Lipopolysaccharides; Male; Metformin; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nociception; Permeability; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Stress, Physiological; Sulpiride | 2019 |
Taurine Ameliorates Thyroid Hypofunction and Renal Injury in L-NAME-Induced Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Dietary Supplements; Disease Models, Animal; Humans; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats; Rats, Wistar; Renal Insufficiency; Taurine; Thyroid Gland | 2019 |
Aucubin Protects against Myocardial Infarction-Induced Cardiac Remodeling via nNOS/NO-Regulated Oxidative Stress.
Topics: Animals; Cell Line; Disease Models, Animal; Echocardiography; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; Iridoid Glucosides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitrogen Oxides; Oxidative Stress; Rats; Reactive Oxygen Species; Thioredoxins; Ventricular Remodeling | 2018 |
LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Croton Oil; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dexamethasone; Disease Models, Animal; Edema; Formaldehyde; Hindlimb; Histamine; Hydrazones; Indomethacin; Inflammation; Male; Mice; Molecular Docking Simulation; NG-Nitroarginine Methyl Ester; Nociception; Nociceptive Pain; Ondansetron; Prostaglandins | 2018 |
ADMA, homocysteine and redox status improvement affected by 7-nitroindazole in spontaneously hypertensive rats.
Topics: Animals; Aorta; Arginine; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Homocysteine; Hypertension; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidation-Reduction; Rats, Inbred SHR | 2018 |
PDI-mediated S-nitrosylation of DRP1 facilitates DRP1-S616 phosphorylation and mitochondrial fission in CA1 neurons.
Topics: Animals; Cysteine; Disease Models, Animal; Dynamins; Male; Mitochondria; Mitochondrial Dynamics; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphorylation; Protein Disulfide-Isomerases; Proteolysis; Rats; Rats, Sprague-Dawley; Serine; Status Epilepticus | 2018 |
The Effects of Lipopolysaccharide on the Disrupted Blood-Brain Barrier in a Rat Model of Preeclampsia.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Cerebral Cortex; Disease Models, Animal; Endothelial Cells; Female; Hippocampus; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Proteinuria; Rats, Sprague-Dawley | 2018 |
Repetitive remote occlusion (RRO) stimulates eNOS-dependent blood flow and collateral expansion in hindlimb ischemia.
Topics: Animals; Benzoates; Blood Flow Velocity; Case-Control Studies; Disease Models, Animal; Enzyme Activators; Femoral Artery; Guanylate Cyclase; Hindlimb; Humans; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peripheral Arterial Disease; Pilot Projects; Regional Blood Flow; Therapeutic Occlusion | 2018 |
Renoprotective Effects of Antroquinonol in Rats with N
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Antrodia; Arginine; Arterioles; Biological Products; Biomarkers; Blood Pressure; Disease Models, Animal; Hypertension; Inflammation; Kidney; Kidney Diseases; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats, Wistar; Ubiquinone | 2018 |
Cardioprotective and anti-apoptotic effects of Potentilla reptans L. root via Nrf2 pathway in an isolated rat heart ischemia/reperfusion model.
Topics: Animals; Apoptosis; Arrhythmias, Cardiac; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NF-E2-Related Factor 2; NG-Nitroarginine Methyl Ester; Plant Extracts; Plant Roots; Potentilla; Rats; Rats, Wistar; Reactive Oxygen Species | 2018 |
Hydrogen sulfide improves vascular repair by promoting endothelial nitric oxide synthase-dependent mobilization of endothelial progenitor cells.
Topics: Animals; Carotid Artery Injuries; Cell Adhesion; Cell Movement; Cells, Cultured; Disease Models, Animal; Endothelial Progenitor Cells; Endothelium; Enzyme Inhibitors; Humans; Hydrogen Sulfide; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Re-Epithelialization; Sulfides | 2019 |
Physical exercise prevents memory impairment in an animal model of hypertension through modulation of CD39 and CD73 activities and A2A receptor expression.
Topics: 5'-Nucleotidase; Animals; Antigens, CD; Apyrase; Cerebral Cortex; Disease Models, Animal; Hypertension; Memory; NG-Nitroarginine Methyl Ester; Physical Conditioning, Animal; Rats; Receptor, Adenosine A2A; Swimming | 2019 |
Bypassing major venous occlusion and duodenal lesions in rats, and therapy with the stable gastric pentadecapeptide BPC 157, L-NAME and L-arginine.
Topics: Animals; Arginine; Colitis, Ischemic; Collateral Circulation; Disease Models, Animal; Duodenum; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Peptide Fragments; Protective Agents; Proteins; Random Allocation; Rats; Rats, Wistar; Treatment Outcome; Veins; Venous Thrombosis | 2018 |
Counteraction of perforated cecum lesions in rats: Effects of pentadecapeptide BPC 157, L-NAME and L-arginine.
Topics: Animals; Anti-Ulcer Agents; Arginine; Cecum; Disease Models, Animal; Drug Therapy, Combination; Humans; Intestinal Perforation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Proteins; Rats; Rats, Wistar; Treatment Outcome; Wound Healing | 2018 |
Non-alcoholic steatohepatitis aggravates nitric oxide synthase inhibition-induced arteriosclerosis in SHRSP5/Dmcr rat model.
Topics: Animals; Arteriosclerosis; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Heart Ventricles; Liver; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Non-alcoholic Fatty Liver Disease; Organ Size; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Dysfunction, Left | 2018 |
Resveratrol promotes trophoblast invasion in pre-eclampsia by inducing epithelial-mesenchymal transition.
Topics: Animals; Antihypertensive Agents; beta Catenin; Cadherins; Cell Movement; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Humans; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Resveratrol; Trophoblasts; Vimentin; Wnt Proteins; Wnt Signaling Pathway | 2019 |
Effect of co-administration of BRL-37344 and tadalafil on reduction of overactive bladder symptoms after induction of detrusor overactivity in mice1.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Ethanolamines; Male; Mice; NG-Nitroarginine Methyl Ester; Random Allocation; Tadalafil; Urinary Bladder, Overactive; Urination; Urological Agents | 2019 |
From single drug targets to synergistic network pharmacology in ischemic stroke.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Cell Death; Disease Models, Animal; Drug Combinations; Drug Discovery; Drug Synergism; Female; Male; Mice; NADPH Oxidase 4; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyrazoles; Pyridones; Reactive Oxygen Species; Stroke | 2019 |
Tetramethylpyrazine reduces the consequences of nitric oxide inhibition in pregnant rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation; Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Placenta; Pre-Eclampsia; Pregnancy; Pyrazines; Rats; Transcription Factor CHOP; Vascular Endothelial Growth Factor Receptor-1 | 2019 |
Connexin37-Dependent Mechanisms Selectively Contribute to Modulate Angiotensin II -Mediated Hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Connexins; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gap Junction alpha-4 Protein; Hypertension; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; NG-Nitroarginine Methyl Ester; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 2; Renin; Vasoconstrictor Agents | 2019 |
Nitrosative stress drives heart failure with preserved ejection fraction.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Endoribonucleases; Heart Failure; Humans; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitrosative Stress; Phenotype; Protein Serine-Threonine Kinases; Signal Transduction; Stroke Volume; X-Box Binding Protein 1 | 2019 |
Synthesis of Nomega-Nitro-l-arginine methyl ester modified reduced graphene oxide nanosheets and their protective action on experimental preeclampsia in mice.
Topics: Animals; Chemistry Techniques, Synthetic; Disease Models, Animal; Female; Graphite; Male; Mice; Nanostructures; NG-Nitroarginine Methyl Ester; Oxidation-Reduction; Oxidative Stress; Oxides; Pre-Eclampsia; Pregnancy | 2019 |
CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling.
Topics: Adult; Animals; Basigin; Disease Models, Animal; Doxorubicin; Female; Focal Adhesion Kinase 1; Glomerulosclerosis, Focal Segmental; Humans; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Podocytes; Proteinuria; Signal Transduction | 2019 |
The Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia⁻Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats.
Topics: Animals; Biomarkers; Cholestasis, Intrahepatic; Cytokines; Disease Models, Animal; Hyaluronic Acid; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Inflammation Mediators; Lipid Peroxidation; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Reperfusion Injury | 2019 |
Ameliorative effects of pre-eclampsia by quercetin supplement to aspirin in a rat model induced by L-NAME.
Topics: Animals; Aspirin; Blood Pressure; Cytokines; Dietary Supplements; Disease Models, Animal; Female; Inflammation Mediators; Lipid Peroxidation; NG-Nitroarginine Methyl Ester; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Proteinuria; Quercetin; Rats, Sprague-Dawley; RNA, Messenger; Systole; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2019 |
Impairment of Nrf2- and Nitrergic-Mediated Gastrointestinal Motility in an MPTP Mouse Model of Parkinson's Disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Biopterins; Blotting, Western; Colon; Constipation; Disease Models, Animal; Enzyme Inhibitors; Gastric Emptying; Gastrointestinal Motility; Gene Expression Regulation; Heme Oxygenase-1; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; MPTP Poisoning; NF-E2-Related Factor 2; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Parkinson Disease; Parkinsonian Disorders; Tyrosine 3-Monooxygenase | 2019 |
Effects of N-nitro L-arginine methyl ester and α-tocopherol on testicular oxidative stress caused by exposure to cigarette smoke.
Topics: alpha-Tocopherol; Animals; Antioxidants; Disease Models, Animal; Humans; Male; NG-Nitroarginine Methyl Ester; Nicotiana; Oxidative Stress; Rats; Rats, Wistar; Smoke; Testicular Diseases; Testis; Tobacco Smoking | 2019 |
Protective effect of apelin preconditioning in a rat model of hepatic ischemia reperfusion injury; possible interaction between the apelin/APJ system, Ang II/AT1R system and eNOS.
Topics: Alanine Transaminase; Angiotensin II; Animals; Apelin; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Gene Expression; Ischemic Preconditioning; Liver; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reperfusion Injury | 2019 |
Relationship between changes in the cochlear blood flow and disorder of hearing function induced by blast injury in guinea pigs.
Topics: Animals; Auditory Threshold; Blast Injuries; Cochlea; Disease Models, Animal; Explosions; Female; Guinea Pigs; Hearing Disorders; Hearing Tests; Laser-Doppler Flowmetry; Male; NG-Nitroarginine Methyl Ester; Pressure; Regional Blood Flow | 2013 |
Resistance training controls arterial blood pressure in rats with L-NAME- induced hypertension.
Topics: Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenylephrine; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Wistar; Resistance Training; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2013 |
Effect of post-trial L-NAME administration on cocaine sensitization.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Locomotion; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Long-Evans; Time Factors | 2013 |
Neutrophil-infiltrated paw edema induced by mannose-binding Dioclea violacea lectin.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Cytokines; Dexamethasone; Dioclea; Disease Models, Animal; Edema; Female; Histamine; Mannose-Binding Lectin; Meclizine; Neutrophil Infiltration; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Rats; Rats, Wistar | 2013 |
Involvement of opioidergic and nitrergic systems in memory acquisition and exploratory behaviors in cholestatic mice.
Topics: Analgesics, Opioid; Animals; Arginine; Avoidance Learning; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Ligation; Male; Memory Disorders; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide | 2013 |
Evaluation of functional relationship between mouse hippocampal cholinergic and nitrergic systems in anxiogenic-like behavior.
Topics: Analysis of Variance; Animals; Anxiety; Arginine; Cholinergic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Male; Maze Learning; Mecamylamine; Mice; Microinjections; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Nitric Oxide | 2013 |
Endothelium-dependent relaxations in the aorta from K(2p)6.1 knockout mice.
Topics: Animals; Aorta, Thoracic; Calcimycin; Disease Models, Animal; Endothelium, Vascular; Hypertension; Indomethacin; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Phenylephrine; Potassium Channels, Tandem Pore Domain; Vasoconstriction; Vasodilation | 2013 |
Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Arthritis, Experimental; Aspirin; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Female; Losartan; Muscle Relaxation; Muscle, Smooth, Vascular; Myography; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2013 |
Prenatal intestinal obstruction affects the myenteric plexus and causes functional bowel impairment in fetal rat experimental model of intestinal atresia.
Topics: Animals; Area Under Curve; Atropine; Choline O-Acetyltransferase; Disease Models, Animal; Fetal Diseases; Gastrointestinal Motility; Horseradish Peroxidase; Humans; Infant, Newborn; Intestinal Atresia; Mannitol; Myenteric Plexus; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Permeability; Rats; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric | 2013 |
High salt-induced hypertension in B2 knockout mice is corrected by the ETA antagonist, A127722.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Atrasentan; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Peptides, Cyclic; Pyrrolidines; Receptor, Bradykinin B2; Sodium; Sodium Chloride, Dietary; Telemetry | 2013 |
Effects of vitamin D3 derivative--calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcitriol; Dihydrotestosterone; Disease Models, Animal; Female; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2013 |
Gender Based Differences in Stress-induced Gastric Ulcer Formation and its Regulation by Nitric Oxide (NO): An Experimental Study.
Topics: Androstenedione; Animals; Arginine; Aromatase Inhibitors; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogens; Female; Glutathione; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats, Wistar; Severity of Illness Index; Sex Factors; Signal Transduction; Stomach Ulcer; Stress, Psychological | 2015 |
Citronellal, a monoterpene present in Java citronella oil, attenuates mechanical nociception response in mice.
Topics: Acyclic Monoterpenes; Aldehydes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Cymbopogon; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Indonesia; KATP Channels; Male; Mice; Monoterpenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nociceptive Pain; Oils, Volatile; Pain Threshold; Plant Oils; Potassium Channel Blockers; Signal Transduction | 2013 |
Diminished contractile responses of isolated conduit arteries in two rat models of hypertension.
Topics: Animals; Arteries; Disease Models, Animal; Hypertension; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Vasoconstriction | 2013 |
Resveratrol and grape juice differentially ameliorate cardiovascular autonomic modulation in L-NAME-treated rats.
Topics: Animals; Autonomic Nervous System; Beverages; Cardiovascular System; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; NG-Nitroarginine Methyl Ester; Oxidation-Reduction; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasodilator Agents; Vitis | 2013 |
The effects of tempol on renal function and hemodynamics in cyclosporine-induced renal insufficiency rats.
Topics: Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Cyclosporine; Disease Models, Animal; Hemodynamics; Hypertension; Kidney; Kidney Concentrating Ability; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Insufficiency; Spin Labels; Superoxide Dismutase | 2013 |
[Study of L-NAME treatment on experimental autoimmune myocarditis].
Topics: Animals; Apoptosis; Autoimmune Diseases; Caspase 3; Caspase 8; Caspase 9; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II | 2013 |
Potent antihypertensive activity of Thai-Lanna medicinal plants and recipes from "MANOSROI III" database.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Databases, Factual; Disease Models, Animal; Heart Rate; Hypertension; Male; Medicine, Traditional; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Preparations; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Thailand | 2013 |
Female SHR have greater blood pressure sensitivity and renal T cell infiltration following chronic NOS inhibition than males.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hypertension; Inflammation; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Sex Factors; T-Lymphocytes; Time Factors | 2013 |
Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: implications for gene therapy of restenosis.
Topics: Adenoviridae; Animals; Aorta; Arginine; Biopterins; Carotid Arteries; Cell Proliferation; Cell Survival; Coronary Restenosis; Cross-Linking Reagents; Disease Models, Animal; Genetic Therapy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2013 |
Nitric oxide synthase, calcitonin gene-related peptide and NK-1 receptor mechanisms are involved in GTN-induced neuronal activation.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Dipeptides; Disease Models, Animal; Enzyme Inhibitors; Humans; Male; Migraine Disorders; Neurokinin-1 Receptor Antagonists; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitroglycerin; Piperazines; Piperidines; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Trigeminal Nerve; Vasodilator Agents; Wakefulness | 2014 |
Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice.
Topics: Adherens Junctions; Anaphylaxis; Animals; Aorta; beta Catenin; Capillary Permeability; Disease Models, Animal; Endothelial Cells; Enzyme Activation; Gene Deletion; Lung; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Platelet Activating Factor; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Signal Transduction | 2013 |
Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Indazoles; Male; Membrane Glycoproteins; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Receptors, Complement; RNA, Messenger; Sciatica; Spinal Cord; Time Factors | 2013 |
Aldehyde dehydrogenase 2 partly mediates hypotensive effect of nitrite on L-NAME-induced hypertension in normoxic rat.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrazines; Hypertension; Male; Mitochondrial Proteins; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Time Factors | 2014 |
Influence of decompression sickness on vasomotion of isolated rat vessels.
Topics: Acetylcholine; Animals; Catecholamines; Decompression Sickness; Disease Models, Animal; Diving; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hydrocortisone; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenylephrine; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2014 |
Hyperoxia-induced developmental plasticity of the hypoxic ventilatory response in neonatal rats: contributions of glutamate-dependent and PDGF-dependent mechanisms.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzamides; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hyperoxia; Hypoxia; Imatinib Mesylate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Piperazines; Platelet-Derived Growth Factor; Pulmonary Ventilation; Pyrimidines; Rats; Rats, Sprague-Dawley | 2014 |
Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration.
Topics: Animals; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Glioma; Heterografts; Humans; Integrins; Matrix Metalloproteinase 9; Mice; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Binding; Receptors, Urokinase Plasminogen Activator; RNA Interference | 2013 |
Genetic variants on rat chromosome 8 exhibit profound effects on hypertension severity and survival during nitric oxide inhibition in spontaneously hypertensive rats.
Topics: Albuminuria; Animals; Blood Pressure; Chromosomes, Mammalian; Disease Models, Animal; Enzyme Inhibitors; Genetic Predisposition to Disease; Genetic Variation; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenotype; Quantitative Trait Loci; Rats; Rats, Inbred SHR; Severity of Illness Index; Time Factors | 2014 |
L-carnitine attenuates the development of kidney fibrosis in hypertensive rats by upregulating PPAR-γ.
Topics: Animals; Carnitine; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Hypertension; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Interleukin-6; Kidney Diseases; Kidney Tubules, Proximal; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; NG-Nitroarginine Methyl Ester; PPAR gamma; Rats; Rats, Wistar; Transforming Growth Factor beta1; Up-Regulation | 2014 |
A newly synthesized compound, 4'-geranyloxyferulic acid-N(omega)-nitro-L-arginine methyl ester suppresses inflammation-associated colorectal carcinogenesis in male mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Coumaric Acids; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitroarginine; RNA-Binding Proteins | 2014 |
PI3K-Akt/eNOS in remote postconditioning induced by brief pulmonary ischemia.
Topics: Animals; Creatine Kinase; Disease Models, Animal; Ischemic Preconditioning; Lung; Male; Malondialdehyde; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rabbits; rho-Associated Kinases; Superoxide Dismutase | 2014 |
Analysis of placental vascularization in a pharmacological rabbit model of IUGR induced by L-NAME, a nitric oxide synthase inhibitor.
Topics: Animals; Disease Models, Animal; Female; Fetal Growth Retardation; Gene Expression; Maternal-Fetal Exchange; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitroarginine; Placenta; Pregnancy; Rabbits | 2014 |
Panax quinquefolium involves nitric oxide pathway in olfactory bulbectomy rat model.
Topics: Anhedonia; Animals; Arginine; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Olfactory Bulb; Panax; Phytotherapy; Plant Preparations; Rats, Wistar; Signal Transduction | 2014 |
Decreased endothelial nitric oxide, systemic oxidative stress, and increased sympathetic modulation contribute to hypertension in obese rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium Glutamate; Sympathetic Nervous System | 2014 |
In vitro smooth muscle contractility before and after relief of experimental obstruction in the rat: application to the surgical management of ileal dilatation.
Topics: Acetylcholine; Animals; Dilatation, Pathologic; Disease Models, Animal; Electric Stimulation; Gastrointestinal Motility; Histamine; Ileal Diseases; In Vitro Techniques; Intestinal Obstruction; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Postoperative Period; Potassium Chloride; Random Allocation; Rats; Rats, Wistar; Substance P | 2014 |
Antidepressant-like effect of nitric oxide synthase inhibitors and sildenafil against lipopolysaccharide-induced depressive-like behavior in mice.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cyclic GMP; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Imipramine; Interleukin-1beta; Lipopolysaccharides; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones | 2014 |
Serotonin depletion can enhance the cerebrovascular responses induced by cortical spreading depression via the nitric oxide pathway.
Topics: Analysis of Variance; Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Male; Methamphetamine; Microscopy, Electron, Transmission; Microvessels; Migraine Disorders; NG-Nitroarginine Methyl Ester; Potassium Chloride; Rats; Rats, Wistar; Serotonin; Vascular Cell Adhesion Molecule-1 | 2015 |
Metallothionein-1 and nitric oxide expression are inversely correlated in a murine model of Chagas disease.
Topics: Animals; Antioxidants; Chagas Disease; Disease Models, Animal; Enzyme Inhibitors; Female; Heart; Metallothionein; Mice, Inbred BALB C; Muscle, Skeletal; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Parasitemia; Real-Time Polymerase Chain Reaction; Statistics, Nonparametric; Time Factors; Trypanosoma cruzi | 2014 |
Estrogen protects against intracranial aneurysm rupture in ovariectomized mice.
Topics: Aged; Aneurysm, Ruptured; Animals; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Fulvestrant; Humans; Intracranial Aneurysm; Mice; Mice, Inbred C57BL; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitriles; Ovariectomy; Phenols; Pyrazoles; Subarachnoid Hemorrhage | 2014 |
Nitric oxide mediates the anticonvulsant effects of thalidomide on pentylenetetrazole-induced clonic seizures in mice.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Seizures; Thalidomide | 2014 |
The effects of magnesium sulphate on the contractile activity of uterus in an animal model of preeclampsia.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Female; Magnesium Sulfate; NG-Nitroarginine Methyl Ester; Oxytocics; Oxytocin; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Uterine Contraction | 2014 |
Inhibition of inducible nitric oxide synthesis ameliorates liver ischemia and reperfusion injury induced transient increase in arterial stiffness.
Topics: Amidines; Animals; Benzylamines; Biomarkers; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Inflammation Mediators; Liver; Liver Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Pulse Wave Analysis; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Vascular Stiffness | 2014 |
Inhibition of inducible nitric oxide synthase ameliorates myocardial ischemia/reperfusion injury - induced acute renal injury.
Topics: Acute Kidney Injury; Amidines; Animals; Benzylamines; Biomarkers; Blood Pressure; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Injections, Intraperitoneal; Kidney; Male; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Rats, Sprague-Dawley; Time Factors | 2014 |
[Variability of plasma angiotensinogen levels and risk of hypertension in a transgenic rat model].
Topics: Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Transgenic | 2014 |
Central exogenous nitric oxide decreases cardiac sympathetic drive and improves baroreflex control of heart rate in ovine heart failure.
Topics: Animals; Baroreflex; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; Heart; Heart Failure; Heart Rate; Injections, Intraventricular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitroprusside; Sheep; Sympathetic Nervous System | 2014 |
The antihypertensive effects of sodium nitrite are not associated with circulating angiotensin converting enzyme inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Sodium Nitrite; Structure-Activity Relationship | 2014 |
The anti-inflammatory and antioxidant effects of pravastatin and nebivolol in rat aorta.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Aorta; Ceruloplasmin; Cholesterol; Coronary Artery Disease; Disease Models, Animal; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Nebivolol; NG-Nitroarginine Methyl Ester; Pravastatin; Rats; Rats, Wistar; Triglycerides; Uric Acid | 2014 |
The effects of coenzyme Q10 on seizures in mice: the involvement of nitric oxide.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Electroshock; Epilepsy, Tonic-Clonic; Guanidines; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Seizures; Ubiquinone | 2014 |
Endothelial nitric oxide synthase and superoxide mediate hemodynamic initiation of intracranial aneurysms.
Topics: Animals; Cyclic N-Oxides; Disease Models, Animal; Female; Intracranial Aneurysm; Matrix Metalloproteinases, Membrane-Associated; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protein Synthesis Inhibitors; Rabbits; Reactive Oxygen Species; Spin Labels; Superoxides | 2014 |
Akt1-mediated fast/glycolytic skeletal muscle growth attenuates renal damage in experimental kidney disease.
Topics: Adiponectin; Animals; Cytokines; Disease Models, Animal; Fibrosis; Glycolysis; Inflammation; Kidney; Mice; Mice, Transgenic; Muscle Proteins; Muscle, Skeletal; Muscles; Muscular Atrophy; Myofibroblasts; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Physical Conditioning, Animal; Proto-Oncogene Proteins c-akt; Renal Insufficiency; SKP Cullin F-Box Protein Ligases | 2014 |
High-density lipoprotein from patients with coronary heart disease loses anti-thrombotic effects on endothelial cells: impact on arterial thrombus formation.
Topics: Acute Coronary Syndrome; Adult; Aged; Animals; Aorta; Blood Coagulation; Carotid Artery Injuries; Cells, Cultured; Coronary Disease; Disease Models, Animal; Endothelial Cells; Humans; Lipoproteins; Lipoproteins, HDL; Mice; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Thrombin; Thromboplastin; Tissue Plasminogen Activator | 2014 |
Different effect of l-NAME treatment on susceptibility to decompression sickness in male and female rats.
Topics: Animals; Decompression Sickness; Disease Models, Animal; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors | 2014 |
Low molecular weight heparin improves proteinuria in rats with L-NAME induced preeclampsia by decreasing the expression of nephrin, but not podocin.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Heparin, Low-Molecular-Weight; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Proteinuria; Random Allocation; Rats, Wistar | 2015 |
Different effects of 7-nitroindazole and L-NAME administered both individually and together on the cardiovascular system of the rat.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiomegaly; Carotid Arteries; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats, Inbred SHR; Rats, Wistar; Vascular Remodeling; Vasodilation; Ventricular Remodeling | 2015 |
Vanillic acid: a potential inhibitor of cardiac and aortic wall remodeling in l-NAME induced hypertension through upregulation of endothelial nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypertension; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats, Wistar; Vanillic Acid; Ventricular Function, Left | 2014 |
The optimization of a chronic nitric oxide synthase (NOS) inhibition model of pre-eclampsia by evaluating physiological changes.
Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Fetal Weight; Litter Size; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Parturition; Piperazines; Pre-Eclampsia; Pregnancy; Proteinuria; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfonamides; Time Factors; Urine; Vasodilator Agents | 2014 |
Noninvasive metabolic syndrome model using an extremely small minipig, the microminipig.
Topics: Animals; Atherosclerosis; Blood Pressure; Cardiomegaly; Cholesterol, Dietary; Coronary Vessels; Diet, High-Fat; Disease Models, Animal; Drug Discovery; Endothelium, Vascular; Lipoproteins, LDL; Male; Metabolic Syndrome; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Swine; Swine, Miniature | 2014 |
Effect of nitric oxide pathway regulation on water/sodium balance and renal function in a rodent model of acute liver and renal failure.
Topics: Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Kidney; Kidney Function Tests; Liver; Liver Failure, Acute; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Osmolar Concentration; Rats, Sprague-Dawley; Water-Electrolyte Balance | 2014 |
Measurement of endothelium-dependent vasodilation in mice--brief report.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Flow Velocity; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Hindlimb; Humans; Hyperemia; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Ultrasonography; Vasodilation | 2014 |
Direct renin inhibitor therapy and swimming training: hemodynamic and cardiac effects in hypertensive and normotensive rats.
Topics: Amides; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Fumarates; Heart; Hypertension; Male; NG-Nitroarginine Methyl Ester; Physical Conditioning, Animal; Rats; Rats, Wistar; Renin; Risk Factors; Swimming | 2015 |
(-)-Epicatechin prevents alterations in the metabolism of superoxide anion and nitric oxide in the hearts of L-NAME-treated rats.
Topics: Animals; Antihypertensive Agents; Catechin; Coronary Vessels; Dietary Supplements; Disease Models, Animal; Enzyme Activation; Fruit; Heart Ventricles; Hypertension; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Random Allocation; Rats, Sprague-Dawley; Stereoisomerism; Superoxides; Vegetables | 2015 |
Granulocyte colony-stimulating factor ameliorates coronary artery elastin breakdown in a mouse model of Kawasaki disease.
Topics: Animals; Coronary Vessels; Disease Models, Animal; Elastin; Endothelial Progenitor Cells; Granulocyte Colony-Stimulating Factor; Male; Mice; Mice, Inbred C57BL; Mucocutaneous Lymph Node Syndrome; NG-Nitroarginine Methyl Ester; Nitrogen Oxides | 2014 |
Resveratrol attenuates inflammation in the rat heart subjected to ischemia-reperfusion: Role of the TLR4/NF-κB signaling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Disease Models, Animal; Down-Regulation; Heart; Inflammation; Male; Myocardial Reperfusion Injury; Myocardium; Neutrophils; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Overexpression of NMDAR2B in an inflammatory model of Alzheimer's disease: modulation by NOS inhibitors.
Topics: Alzheimer Disease; Amidines; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Benzylamines; Brain; Diflunisal; Disease Models, Animal; Enzyme Inhibitors; Exploratory Behavior; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Male; Maze Learning; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate | 2014 |
Heme Oxygenase Improves Renal Function by Potentiating Podocyte-Associated Proteins in Nω-Nitro-l-Arginine-Methyl Ester (l-NAME)-Induced Hypertension.
Topics: Animals; Arginine; Biomarkers; Cytoprotection; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibrosis; Heme; Heme Oxygenase (Decyclizing); Hypertension; Inflammation Mediators; Kidney; Male; Mesoporphyrins; NG-Nitroarginine Methyl Ester; Oxidative Stress; Podocytes; Rats, Sprague-Dawley; Signal Transduction | 2015 |
Mechanisms of α-mangostin-induced antinociception in a rodent model.
Topics: Analgesics; Animals; Arginine; Capsaicin; Disease Models, Animal; Glutamic Acid; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Rats; Xanthones | 2015 |
Intestinal NADPH oxidase 2 activity increases in a neonatal rat model of necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enteral Nutrition; Enterocolitis, Necrotizing; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Hypoxia; Intestines; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha | 2014 |
Developmental and Functional Brain Impairment in Offspring from Preeclampsia-Like Rats.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Brain; Cell Proliferation; Disease Models, Animal; Female; Hippocampus; Learning; Memory; Neurogenesis; Neuroglia; Neurons; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats, Sprague-Dawley; Stem Cells | 2016 |
[Effect of astaxanthin on preeclampsia rat model].
Topics: Animals; Blood Pressure; Caspase 3; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Malondialdehyde; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Superoxide Dismutase; Xanthophylls | 2014 |
PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.
Topics: Amiloride; Angiotensin II; Animals; Arteries; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Epithelial Sodium Channels; Female; Hypertension; Kidney; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases; Sodium; Sodium Chloride, Dietary | 2015 |
Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness.
Topics: Animals; Cerebral Arteries; Disease Models, Animal; Elastin; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Mice; Mice, Knockout; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Vascular Resistance; Vascular Stiffness; Vasodilation | 2015 |
Involvement of nitric oxide in serotonin-induced scratching in mice.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Injections, Intradermal; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pruritus; Serotonin; Serotonin Receptor Agonists | 2015 |
Nitric oxide synthase inhibition abolishes exercise-mediated protection against isoproterenol-induced cardiac hypertrophy in female mice.
Topics: Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Echocardiography; Enzyme Inhibitors; Female; Fibrosis; Isoproterenol; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Physical Conditioning, Animal; Real-Time Polymerase Chain Reaction; Up-Regulation | 2015 |
Investigation of the effects of enteral hormones on the pyloric muscle in newborn rats.
Topics: Animals; Animals, Newborn; Arginine; Disease Models, Animal; Enzyme Inhibitors; Female; Male; NG-Nitroarginine Methyl Ester; Pyloric Stenosis, Hypertrophic; Pylorus; Rats; Rats, Wistar | 2015 |
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Captopril; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypertension, Renal; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Random Allocation; Rats, Wistar; Renin; RNA, Messenger | 2015 |
Low-molecular-weight heparin protects kidney through an anti-apoptotic mechanism in a rat pre-eclamptic model.
Topics: Animals; Anticoagulants; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Blood Urea Nitrogen; Caspase 3; Creatinine; Disease Models, Animal; Female; Fetal Weight; Heparin, Low-Molecular-Weight; Kidney; Litter Size; NG-Nitroarginine Methyl Ester; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger | 2015 |
Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse.
Topics: Animals; Cells, Cultured; Cyclic GMP; Diet, High-Fat; Disease Models, Animal; Down-Regulation; Endothelial Cells; Histone Deacetylase 2; Hypercholesterolemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Penile Erection; Penis; Phosphorylation; Recombinant Fusion Proteins; Regional Blood Flow; Tight Junction Proteins | 2015 |
Apelin inhibits the activation of the nucleotide-binding domain and the leucine-rich, repeat-containing family, pyrin-containing 3 (NLRP3) inflammasome and ameliorates insulin resistance in severely burned rats.
Topics: Analysis of Variance; Animals; Apelin; Binding Sites; Burns; Carrier Proteins; Cytokines; Cytoskeletal Proteins; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucose Tolerance Test; Inflammasomes; Injury Severity Score; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Leucine; Male; NG-Nitroarginine Methyl Ester; NLR Family, Pyrin Domain-Containing 3 Protein; Pyrin; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate | 2015 |
Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Benzeneacetamides; Calcium Channels, N-Type; Cerebral Cortex; Channelopathies; Cortical Synchronization; Disease Models, Animal; Enzyme Inhibitors; Female; Male; Mice; Mice, Transgenic; Mutation; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Potassium Channel Blockers; Pyridines; Quinoxalines; Vibrissae | 2015 |
Systemic Aldosterone, But Not Angiotensin II, Plays a Pivotal Role in the Pathogenesis of Renal Injury in Chronic Nitric Oxide-Deficient Male Rats.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Chemokine CCL2; Disease Models, Animal; Enzyme Inhibitors; Kidney; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Osteopontin; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Messenger; Time Factors; Transforming Growth Factor beta1 | 2015 |
Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Hippocampus; Humans; In Vitro Techniques; Mice; Mice, Transgenic; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Presenilin-1; Ryanodine Receptor Calcium Release Channel; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; tau Proteins | 2015 |
Chronic Hypertension Leads to Neurodegeneration in the TgSwDI Mouse Model of Alzheimer's Disease.
Topics: Age of Onset; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood-Brain Barrier; Brain; Cerebral Amyloid Angiopathy; Chronic Disease; Dementia, Vascular; Disease Models, Animal; Female; Hippocampus; Humans; Hypertension; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Mutation; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Pericytes; Vasculitis | 2015 |
Effect of Sildenafil on Pre-Eclampsia-Like Mouse Model Induced By L-Name.
Topics: Animals; Disease Models, Animal; Female; Fetus; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Sildenafil Citrate; Vasodilator Agents | 2015 |
Effects of L-arginine and L-NAME on ischemia-reperfusion in rat liver.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Disease Models, Animal; Enzyme Inhibitors; Liver; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats, Wistar; Reference Values; Reperfusion Injury; Reproducibility of Results; Time Factors; Treatment Outcome | 2015 |
Impaired capsaicin-induced relaxation in diabetic mesenteric arteries.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Peptide Fragments; Rats; Rats, Sprague-Dawley; TRPV Cation Channels; Vasodilation; Vasodilator Agents | 2015 |
Microglia participate in neurogenic regulation of hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Diphtheria Toxin; Disease Models, Animal; Hypertension; Infusions, Intraventricular; Mice; Mice, Inbred C57BL; Microglia; NG-Nitroarginine Methyl Ester; Sympathetic Nervous System | 2015 |
Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity.
Topics: Action Potentials; Amidohydrolases; Animals; Cells, Cultured; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Nerve Fibers; Nerve Tissue Proteins; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Nociception; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Dorsal Horn | 2015 |
Glomerulosclerosis in the diet-induced obesity model correlates with sensitivity to nitric oxide inhibition but not glomerular hyperfiltration or hypertrophy.
Topics: Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glomerular Filtration Rate; Glomerulonephritis; Hemodynamics; Hypertension; Hypertrophy; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Proteinuria; Rats, Sprague-Dawley; Renal Circulation; Time Factors; Vascular Resistance | 2015 |
Effect of magnesium supplementation on blood pressure and vascular reactivity in nitric oxide synthase inhibition-induced hypertension model.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Magnesium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 2015 |
Evaluation of urine fibrinogen level in a murine model of contrast-induced nephropathy.
Topics: Acute Kidney Injury; Animals; Biomarkers; Creatinine; Disease Models, Animal; Early Diagnosis; Fibrinogen; Gene Expression Regulation; Indomethacin; Kidney; Male; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Predictive Value of Tests; Time Factors; Triiodobenzoic Acids; Urinalysis | 2016 |
Granulocyte-Colony Stimulating Factor Increases Cerebral Blood Flow via a NO Surge Mediated by Akt/eNOS Pathway to Reduce Ischemic Injury.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats; Reperfusion Injury; Signal Transduction | 2015 |
Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Kidney; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Sodium Chloride, Dietary | 2015 |
Involvement of NO-cGMP pathway in anti-hyperalgesic effect of PDE5 inhibitor tadalafil in experimental hyperalgesia.
Topics: Animals; Carrageenan; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Tadalafil | 2015 |
Barnidipine ameliorates the vascular and renal injury in L-NAME-induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Inflammation Mediators; Kidney; Kidney Diseases; Male; Malondialdehyde; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Rats, Wistar; Renal Artery; Time Factors; Vascular Remodeling; Vasoconstriction; Vasodilation | 2015 |
Reactive nitrogen species mediate oxidative stress and astrogliosis provoked by in vivo administration of phytanic acid in cerebellum of adolescent rats: A potential contributing pathomechanism of cerebellar injury in peroxisomal disorders.
Topics: Animals; Astrocytes; Cerebellum; Disease Models, Animal; Gliosis; Homeostasis; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxidative Stress; Peroxisomal Disorders; Phytanic Acid; Rats, Wistar; Reactive Nitrogen Species; Time Factors | 2015 |
Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma.
Topics: Adenoviridae; alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Damage; DNA, Complementary; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Genetic Therapy; Genetic Vectors; Liver; Liver Cirrhosis; Liver Neoplasms; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; RNA, Small Interfering; Rous sarcoma virus; Tumor Suppressor Protein p53 | 2016 |
Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension.
Topics: Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Collagen; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha; Vascular Remodeling; Ventricular Remodeling | 2015 |
β2- and β1-Adrenoceptor Expression Exhibits a Common Regulatory Pattern With GRK2 and GRK5 in Human and Animal Models of Cardiovascular Diseases.
Topics: Animals; Case-Control Studies; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 5; Gene Expression Regulation; Heart Diseases; Humans; Hypertension; NG-Nitroarginine Methyl Ester; Organ Specificity; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; RNA, Messenger | 2015 |
Putative involvement of the nitrergic system on the consolidation, but not initiation, of behavioral sensitization after conspecific alarm substance in zebrafish.
Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Stress, Physiological; Zebrafish | 2015 |
Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.
Topics: Animals; Antidepressive Agents; Colitis; Colon; Crohn Disease; Depression; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hippocampus; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Signal Transduction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2016 |
High glucose-induced changes in hyaloid-retinal vessels during early ocular development of zebrafish: a short-term animal model of diabetic retinopathy.
Topics: Animals; Animals, Genetically Modified; Diabetic Retinopathy; Disease Models, Animal; Glucose; Larva; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Retinal Vessels; Tight Junction Proteins; Vascular Endothelial Growth Factor A; Zebrafish; Zebrafish Proteins | 2016 |
Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in Hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antigens, Ly; Blood Pressure; CD11b Antigen; Cells, Cultured; Disease Models, Animal; Hydrogen Peroxide; Hypertension; Immune Tolerance; Inflammation Mediators; Lymphocyte Activation; Male; Membrane Glycoproteins; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; NADPH Oxidase 2; NADPH Oxidases; Nephritis; NG-Nitroarginine Methyl Ester; Signal Transduction; Sodium, Dietary; T-Lymphocytes; Time Factors | 2015 |
The preferential nNOS inhibitor 7-nitroindazole and the non-selective one N(G)-nitro-L-arginine methyl ester administered alone or jointly with L-DOPA differentially affect motor behavior and monoamine metabolism in sham-operated and 6-OHDA-lesioned rats.
Topics: Adrenergic Agents; Animals; Apomorphine; Biogenic Monoamines; Brain; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Indazoles; Levodopa; Locomotion; Male; Movement Disorders; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxidopamine; Rats; Rats, Wistar; Time Factors | 2015 |
Oral administration of veratric acid, a constituent of vegetables and fruits, prevents cardiovascular remodelling in hypertensive rats: a functional evaluation.
Topics: Administration, Oral; Animals; Antioxidants; Aorta; Ascorbic Acid; Cardiovascular Diseases; Cardiovascular System; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Glutathione; Glutathione Peroxidase; Hypertension; Lipid Peroxidation; Lipid Peroxides; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vanillic Acid; Vascular Remodeling; Vegetables; Vitamin E | 2015 |
Endothelial Mineralocorticoid Receptors Differentially Contribute to Coronary and Mesenteric Vascular Function Without Modulating Blood Pressure.
Topics: Acetylcholine; Animals; Blood Pressure; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Receptors, Mineralocorticoid; Regional Blood Flow; Risk Factors; Vascular Resistance | 2015 |
Persistent change in cardiac fibroblast physiology after transient ACE inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomyopathies; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Collagen Type I; Disease Models, Animal; Enalapril; Fibroblasts; Fibrosis; Granulocyte-Macrophage Colony-Stimulating Factor; Heart Ventricles; Hypertension; Inflammation Mediators; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenotype; Rats, Inbred SHR; Time Factors | 2015 |
Bone Marrow Endothelial Progenitor Cell Transplantation After Ischemic Stroke: An Investigation Into Its Possible Mechanism.
Topics: Animals; Bone Marrow Transplantation; Brain-Derived Neurotrophic Factor; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothelial Progenitor Cells; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Nervous System Diseases; Neurogenesis; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphopyruvate Hydratase; Time Factors | 2015 |
Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model.
Topics: Animals; Blood Pressure; Blood Substitutes; Brain; Disease Models, Animal; Endoglin; Enzyme-Linked Immunosorbent Assay; Female; Fetal Development; Humans; Hypoxia; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Luminescent Measurements; Nanostructures; NG-Nitroarginine Methyl Ester; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Vascular Endothelial Growth Factor Receptor-1 | 2015 |
Experimental model of small subcortical infarcts in mice with long-lasting functional disabilities.
Topics: Animals; Cerebral Infarction; Disease Models, Animal; Endothelin-1; Internal Capsule; Male; Mice; Mice, SCID; NG-Nitroarginine Methyl Ester; Psychomotor Performance; Stroke; Time Factors | 2015 |
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Therapy; Corticosterone; Depressive Disorder; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activation; Fluoxetine; Imipramine; Insulin Resistance; Ketamine; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Conditioning, Animal; Prefrontal Cortex; Ribonucleotides; Triazenes | 2016 |
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hippocampus; Indazoles; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors | 2016 |
Modulation of Hyperosmotic and Immune-Induced Disruption of the Blood-Brain Barrier by the Nitric Oxide System.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Diuretics, Osmotic; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; In Vitro Techniques; Male; Mannitol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Osmotic Pressure; Pyridines; Rats; Rats, Inbred Lew; Time Factors | 2016 |
Helium preconditioning protects against neonatal hypoxia-ischemia via nitric oxide mediated up-regulation of antioxidases in a rat model.
Topics: Animals; Animals, Newborn; Atrophy; Brain; Disease Models, Animal; Enzyme Inhibitors; Helium; Heme Oxygenase (Decyclizing); Hypoxia-Ischemia, Brain; Ischemic Preconditioning; Motor Activity; Neuroprotective Agents; NF-E2-Related Factor 2; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Superoxide Dismutase; Up-Regulation | 2016 |
The Effect of Magnesium on Visual Evoked Potentials in L-NAME-Induced Hypertensive Rats.
Topics: Animals; Disease Models, Animal; Evoked Potentials, Visual; Hypertension; Magnesium; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2016 |
Full Expression of Cardiomyopathy Is Partly Dependent on B-Cells: A Pathway That Involves Cytokine Activation, Immunoglobulin Deposition, and Activation of Apoptosis.
Topics: Angiotensin II; Animals; Apoptosis; B-Lymphocytes; Cardiomyopathies; Collagen; Cytokines; Disease Models, Animal; Fibroblasts; Fibrosis; Genetic Predisposition to Disease; Heart Failure; Hypertrophy, Left Ventricular; Immunoglobulin G; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, SCID; Myocardium; NG-Nitroarginine Methyl Ester; Phenotype; Sialic Acid Binding Ig-like Lectin 2; Signal Transduction; Sodium Chloride; Stroke Volume; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2016 |
NMDA receptor antagonists attenuate the proconvulsant effect of juvenile social isolation in male mice.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Immobility Response, Tonic; Indazoles; Ketamine; Male; Maze Learning; Mice; Motivation; NG-Nitroarginine Methyl Ester; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures; Social Isolation; Statistics, Nonparametric; Swimming; Time Factors | 2016 |
Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in L-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT₁R Expression.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Carthamus tinctorius; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Time Factors; Vasodilation | 2016 |
Nitric oxide pathway activity modulation alters the protective effects of (-)Epigallocatechin-3-gallate on reserpine-induced impairment in rats.
Topics: Animals; Arginine; Catechin; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Glutathione; Hippocampus; Lipid Peroxidation; Male; Memory Disorders; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reserpine; Signal Transduction; Smell; Superoxide Dismutase | 2016 |
Nitric Oxide Deficit Drives Intimal Hyperplasia in Mouse Models of Hypertension.
Topics: Animals; Carotid Arteries; Disease Models, Animal; Hyperplasia; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide | 2016 |
Simultaneous exposure to nitric oxide inhibition and angiotensin II overload: is it a murine model of mitochondrial dysfunction in nonischemic heart failure?
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Failure; Mice; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress | 2016 |
Myeloid-Derived Suppressor Cells Induce the Expansion of Regulatory B Cells and Ameliorate Autoimmunity in the Sanroque Mouse Model of Systemic Lupus Erythematosus.
Topics: Animals; Antibodies, Antinuclear; Autoantibodies; Autoimmunity; B-Lymphocyte Subsets; B-Lymphocytes, Regulatory; Coculture Techniques; Disease Models, Animal; DNA; Enzyme Inhibitors; Germinal Center; Interleukin-10; Kidney; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Plasma Cells; Proteinuria; Spleen; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Th1 Cells; Th17 Cells; Ubiquitin-Protein Ligases | 2016 |
Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney.
Topics: Animals; Disease Models, Animal; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension, Renal; Kidney; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Renal Circulation; Renal Insufficiency, Chronic; Sheep; Solitary Kidney | 2016 |
Extracorporeal shock wave therapy does not improve hypertensive nephropathy.
Topics: Animals; Disease Models, Animal; Hypertension, Renal; Kidney; Lithotripsy; Male; Nephritis; NG-Nitroarginine Methyl Ester; Rats; Treatment Outcome | 2016 |
Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Disease Models, Animal; Female; Humans; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy, Animal; Signal Transduction; Sildenafil Citrate; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-1 | 2016 |
Treatment with the nitric oxide synthase inhibitor L-NAME provides a survival advantage in a mouse model of Kras mutation-positive, non-small cell lung cancer.
Topics: Alleles; Animals; Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Female; Genes, ras; Heterozygote; Humans; Lung Neoplasms; Male; Mice; Mutation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Treatment Outcome | 2016 |
Atorvastatin attenuates the antinociceptive tolerance of morphine via nitric oxide dependent pathway in male mice.
Topics: Animals; Arginine; Atorvastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Opioid-Related Disorders; Pain Measurement; Pain Threshold; Signal Transduction | 2016 |
A new clinically relevant model for intracranial atherosclerosis in rats.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Basilar Artery; Body Weight; Carotid Artery, Internal; Diet, High-Fat; Disease Models, Animal; Eating; Enzyme Inhibitors; Intracranial Arteriosclerosis; Lipids; Male; Middle Cerebral Artery; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 2016 |
The modulatory effect of nitric oxide in pro- and anti-convulsive effects of vasopressin in PTZ-induced seizures threshold in mice.
Topics: Animals; Anticonvulsants; Antidiuretic Hormone Receptor Antagonists; Arginine; Arginine Vasopressin; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Indoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Pyrrolidines; Receptors, Vasopressin; Seizures | 2016 |
Increased pulmonary arteriolar tone associated with lung oxidative stress and nitric oxide in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cerebrovascular Circulation; Disease Models, Animal; Endothelium; Enzyme Inhibitors; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Superoxides | 2016 |
Inhibition of Oxidative Stress in Renal Ischemia-Reperfusion Injury.
Topics: Allopurinol; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Creatinine; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Metalloporphyrins; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Xanthine Oxidase | 2017 |
Sodium hydrosulfide prevents hypertension and increases in vascular endothelial growth factor and soluble fms-like tyrosine kinase-1 in hypertensive pregnant rats.
Topics: Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Disease Models, Animal; Down-Regulation; Female; Fetal Viability; Fetal Weight; Gestational Age; Hypertension, Pregnancy-Induced; Litter Size; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Peroxidase; Placentation; Pregnancy; Rats, Wistar; Sulfides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2016 |
Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a/152 in the placenta of preeclamptic rats and HTR-8 cells.
Topics: Animals; Cytokines; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Fatty Acid-Binding Proteins; Female; Lipid Metabolism; Methylation; MicroRNAs; NG-Nitroarginine Methyl Ester; Placenta; Pre-Eclampsia; Pregnancy; Promoter Regions, Genetic; Rats, Sprague-Dawley; Up-Regulation | 2016 |
The effect of pre-eclampsia-like syndrome induced by L-NAME on learning and memory and hippocampal glucocorticoid receptor expression: A rat model.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Female; Hippocampus; Learning; Memory; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 2017 |
Simvastatin Alleviates Pathology in a Rat Model of Preeclampsia Involving ERK/MAPK Pathway.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-10; Malondialdehyde; MAP Kinase Signaling System; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Pre-Eclampsia; Pregnancy; Rats; Simvastatin; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A | 2017 |
Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: Mechanisms involved in the gastroprotective activity.
Topics: Animals; Antioxidants; Capsaicin; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Ericales; Ethanol; Female; Flavonoids; Gastrointestinal Motility; Glyburide; Histamine; Indomethacin; Male; Mice; Mucus; Naloxone; NG-Nitroarginine Methyl Ester; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Protective Agents; Stomach Ulcer; Water; Yohimbine | 2017 |
The effects of sildenafil citrate on uterine angiogenic status and serum inflammatory markers in an L-NAME rat model of pre-eclampsia.
Topics: Animals; Biomarkers; Blood Pressure; Disease Models, Animal; Female; Gene Expression Regulation; Inflammation; Interferon-gamma; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sildenafil Citrate; Time Factors; Transforming Growth Factor beta; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2017 |
Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity.
Topics: Angiotensin II; Animals; Arterial Pressure; Disease Models, Animal; Epithelial Sodium Channels; Gene Expression Regulation, Enzymologic; Hypertension; Kidney Tubules; Liver; Mice, Transgenic; Natriuresis; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Renal Elimination; Renin-Angiotensin System; Sodium Chloride, Dietary; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 3; Time Factors | 2017 |
The effects of sildenafil citrate on urinary podocin and nephrin mRNA expression in an L-NAME model of pre-eclampsia.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Membrane Proteins; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sildenafil Citrate | 2017 |
The antioxidant effects of green tea reduces blood pressure and sympathoexcitation in an experimental model of hypertension.
Topics: Animals; Antioxidants; Baroreflex; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Sympathetic Nervous System; Tea | 2017 |
The effect of sertraline and 8-OH-DPAT on the PTZ_induced seizure threshold: Role of the nitrergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Piperazines; Pyridines; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sertraline | 2017 |
Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome.
Topics: ADAMTS1 Protein; Adult; Aged; Animals; Aorta; Aortic Aneurysm; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Models, Animal; Enzyme Inhibitors; Female; Fibrillin-1; Gene Knockdown Techniques; Haploinsufficiency; Humans; Immunoblotting; Male; Marfan Syndrome; Mice; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Real-Time Polymerase Chain Reaction | 2017 |
The effects of pollen, propolis, and caffeic acid phenethyl ester on tyrosine hydroxylase activity and total RNA levels in hypertensive rats caused by nitric oxide synthase inhibition: experimental, docking and molecular dynamic studies.
Topics: Adrenal Medulla; Animals; Caffeic Acids; Catalytic Domain; Catecholamines; Disease Models, Animal; Heart; Humans; Hypertension; Hypothalamus; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylethyl Alcohol; Pollen; Propolis; Rats; Tyrosine 3-Monooxygenase | 2018 |
Efficacy of oral supplemental hydration for the prevention of contrast-induced nephropathy in rats.
Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Fluid Therapy; Indomethacin; Iohexol; Male; NG-Nitroarginine Methyl Ester; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Chloride | 2017 |
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Topics: Aging; Angiotensin II; Animals; Cerebral Hemorrhage; Disease Models, Animal; Extracellular Matrix; Gait; Hypertension; Infusion Pumps, Implantable; Insulin-Like Growth Factor I; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phenotype; Psychomotor Performance | 2017 |
Effects of hyperhomocysteinemia on non-adrenergic non-cholinergic relaxation in isolated rat duodenum.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Disease Models, Animal; Duodenum; Electric Stimulation; Enteric Nervous System; Enzyme Inhibitors; Epinephrine; gamma-Aminobutyric Acid; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfathiazoles | 2008 |
Time-dependent alterations in serum NO concentration after oral administration of L-arginine, L-NAME, and allopurinol in intestinal ischemia/reperfusion.
Topics: Administration, Oral; Allopurinol; Animals; Arginine; Catalase; Disease Models, Animal; Enzyme Inhibitors; Intestinal Mucosa; Intestines; Male; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Xanthine Oxidase | 2008 |
Effects of taurine on aortic rings isolated from fructose-fed insulin resistance Sprague-Dawley rat are changed.
Topics: 4-Aminopyridine; Acetylcholine; Administration, Oral; Animals; Aorta; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fructose; Glyburide; In Vitro Techniques; Indomethacin; Insulin; Insulin Resistance; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Peptides; Phenylephrine; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Sprague-Dawley; Taurine; Tetraethylammonium; Vasoconstriction; Vasodilation | 2008 |
Mouse model of focal cerebral ischemia using endothelin-1.
Topics: Animals; Brain Infarction; Brain Ischemia; Carotid Artery Diseases; Cerebral Arteries; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, SCID; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Species Specificity; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Regression of L-NAME-induced hypertension: the role of nitric oxide and endothelium-derived constricting factor.
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Femoral Artery; Hypertension; Hypertrophy, Left Ventricular; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction | 2008 |
[Role of nitric oxide system in pathogenesis of experimental model of hepatorenal syndrome].
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Galactosamine; Hepatorenal Syndrome; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2008 |
Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury.
Topics: Amidines; Animals; Benzylamines; Blood Pressure; Chemokines; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Fluid Therapy; Glutathione Transferase; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Adhesion Molecule-1; Isoenzymes; Liver; Liver Diseases; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peroxidase; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Tyrosine; Wounds and Injuries | 2008 |
Impaired glucose-stimulated insulin secretion in the GK rat is associated with abnormalities in islet nitric oxide production.
Topics: Animals; Arginine; Colforsin; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2008 |
Nitric oxide-mediated neuronal apoptosis in rats with recurrent febrile seizures through endoplasmic reticulum stress pathway.
Topics: Animals; Animals, Newborn; Apoptosis; Caspase 12; Disease Models, Animal; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation; Heat-Shock Proteins; Hippocampus; In Situ Nick-End Labeling; Male; Molecular Chaperones; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Seizures, Febrile; Stress, Physiological; Time Factors | 2008 |
Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia.
Topics: Acetophenones; Animals; Animals, Newborn; Biopterins; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Exhalation; Hypoxia-Ischemia, Brain; Laser-Doppler Flowmetry; Microscopy, Fluorescence; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxygen Inhalation Therapy; Rats; Rats, Wistar; Resuscitation; Superoxides; Time Factors | 2008 |
A role for the thromboxane receptor in L-NAME hypertension.
Topics: Albuminuria; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Drinking; Eating; Enzyme Inhibitors; Hypertension, Renal; Isoprostanes; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Thromboxane A2, Prostaglandin H2; Renin-Angiotensin System; Sodium, Dietary; Thromboxane B2 | 2008 |
Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension.
Topics: Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; Fatty Acids, Unsaturated; Free Radical Scavengers; Hydrazines; Hypoxia; Imidazoles; Indomethacin; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Zucker; Receptors, Thromboxane; Superoxide Dismutase; Thromboxane A2; Thromboxane-A Synthase; Up-Regulation; Vasodilation | 2008 |
Brain-derived neurotrophic factor enhances histamine-induced airway responses and changes levels of exhaled nitric oxide in guinea pigs in vivo.
Topics: Administration, Inhalation; Animals; Brain-Derived Neurotrophic Factor; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Disease Models, Animal; Enzyme Inhibitors; Exhalation; Guinea Pigs; Histamine; Infusions, Intravenous; Injections, Intravenous; Lung; Lung Compliance; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pressure; Time Factors; Vascular Resistance | 2008 |
Role of nitric oxide in the anticonvulsive effect of progesterone.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovariectomy; Pentylenetetrazole; Progesterone; Seizures; Time Factors | 2008 |
Allopurinol attenuates L-NAME induced cardiomyopathy comparable to blockade of angiotensin receptor.
Topics: Allopurinol; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomyopathies; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Imidazoles; Male; Myocardium; NG-Nitroarginine Methyl Ester; Olmesartan Medoxomil; Rats; Rats, Wistar; Tetrazoles; Time Factors; Uric Acid; Ventricular Remodeling; Xanthine Oxidase | 2008 |
Enhanced stress reactivity in nitric oxide synthase type 2 mutant mice: findings in support of astrocytic nitrosative modulation of behavior.
Topics: Analysis of Variance; Animals; Astrocytes; Behavior, Animal; Corticosterone; Disease Models, Animal; Enzyme Inhibitors; Exploratory Behavior; Glial Fibrillary Acidic Protein; Maze Learning; Mice; Mice, Mutant Strains; Mutation; Neocortex; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reaction Time; Recognition, Psychology; Stress, Psychological | 2008 |
The role of inflammatory markers in the cardioprotective effect of L-carnitine in L-NAME-induced hypertension.
Topics: Animals; Biomarkers; Blood Pressure; Body Weight; Cardiotonic Agents; Carnitine; Disease Models, Animal; Hypertension; Interleukin-1beta; Interleukin-6; Male; Myocardium; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tumor Necrosis Factor-alpha | 2008 |
Preconditioning with acute and chronic lithium administration reduces ischemia/reperfusion injury mediated by cyclooxygenase not nitric oxide synthase pathway in isolated rat heart.
Topics: Animals; Cardiotonic Agents; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Lithium Chloride; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Recovery of Function; Ventricular Function, Left; Ventricular Pressure | 2008 |
Paracrine effects of endothelial cells in a diabetic mouse model: capacitative calcium entry stimulated thromboxane release.
Topics: Animals; Aorta; Calcium Signaling; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelial Cells; In Vitro Techniques; Indoles; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Biological; NG-Nitroarginine Methyl Ester; Paracrine Communication; Thromboxanes; Vasoconstriction | 2008 |
Vascular endothelial growth factor attenuates Nomega-nitro-L-arginine methyl ester-induced preeclampsia-like manifestations in rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Female; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2008 |
Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1.
Topics: Acetyl-CoA Carboxylase; Adiponectin; AMP-Activated Protein Kinases; Animals; Caloric Restriction; Caspase 3; Cell Nucleus; Cytochromes c; Disease Models, Animal; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Rats; Rats, Inbred F344; Sirtuin 1; Sirtuins; Time Factors; Up-Regulation; Ventricular Function, Left | 2008 |
Endothelin and gelatinases in renal changes following blockade of nitric oxide synthase in hypertensive rats.
Topics: Animals; Azepines; Blood Urea Nitrogen; Collagen; Creatinine; Cyclic GMP; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gelatinases; Glomerular Filtration Rate; Hypertension; Indoles; Kidney; Matrix Metalloproteinases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Tissue Inhibitor of Metalloproteinase-2 | 2008 |
Abnormal activation of potassium channels in aortic smooth muscle of rats with peritonitis-induced septic shock.
Topics: Animals; Aorta; Barium; Disease Models, Animal; Electrophysiology; KATP Channels; Male; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Peptides; Peritonitis; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Rats; Rats, Inbred WKY; Shock, Septic | 2009 |
Intranasal delivery of insulin and a nitric oxide synthase inhibitor in an experimental model of amyotrophic lateral sclerosis.
Topics: Action Potentials; Administration, Intranasal; Age Factors; Amyotrophic Lateral Sclerosis; Animals; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Humans; Insulin; Mice; Mice, Transgenic; Motor Activity; Motor Neurons; Muscle Strength; Muscle, Skeletal; Mutation; Neural Conduction; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Peripheral Nerves; Signal Transduction; Spinal Cord; Superoxide Dismutase | 2008 |
Role of NOX2 in the regulation of afferent arteriole responsiveness.
Topics: Acetophenones; Adenosine; Angiotensin II; Animals; Arterioles; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney Cortex; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Renal Circulation; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance.
Topics: Animals; Cerebral Arteries; Cyclooxygenase Inhibitors; Diazoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Indomethacin; Insulin Resistance; Male; Metalloporphyrins; Mitochondria; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitro Compounds; Obesity; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Propionates; Rats; Rats, Zucker; Reactive Oxygen Species; Succinate Dehydrogenase; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 2009 |
Antinociceptive effect of chronic lithium on visceral hypersensitivity in a rat model of diarrhea-predominant irritable bowel syndrome: The role of nitric oxide pathway.
Topics: Administration, Oral; Analgesics; Animals; Colon; Defecation; Diarrhea; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Guanidines; Hyperalgesia; Injections, Intraperitoneal; Irritable Bowel Syndrome; Lithium Carbonate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain Measurement; Pain Threshold; Pressure; Rats; Rats, Wistar; Rectum; Restraint, Physical; Stress, Psychological | 2009 |
Experimental induction of salt-sensitive hypertension is associated with lymphocyte proliferative response to HSP70.
Topics: Angiotensin II; Animals; Autoimmunity; Cell Proliferation; Cells, Cultured; Disease Models, Animal; HSP70 Heat-Shock Proteins; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Sprague-Dawley; Salt Tolerance; T-Lymphocytes | 2008 |
Role of endogenous endothelin in endothelial dysfunction in murine model of systemic sclerosis: tight skin mice 1.
Topics: Acetylcholine; Animals; Bosentan; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Receptors, Endothelin; Scleroderma, Systemic; Sulfonamides; Vasodilation; Vasodilator Agents | 2008 |
Solanum indicum ssp. distichum extract is effective against L-NAME-induced hypertension in rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Hypertension; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Rats, Wistar; Solanum; Time Factors | 2008 |
Type 2 diabetes severely impairs structural and functional adaptation of rat resistance arteries to chronic changes in blood flow.
Topics: Acetylcholine; Adaptation, Physiological; Animals; Antioxidants; Caveolin 1; Cyclic N-Oxides; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Ligation; Male; Membrane Glycoproteins; Mesenteric Arteries; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Zucker; Regional Blood Flow; Spin Labels; Splanchnic Circulation; Superoxides; Vascular Resistance; Vasodilation; Vasodilator Agents | 2009 |
L-Serine lowers while glycine increases blood pressure in chronic L-NAME-treated and spontaneously hypertensive rats.
Topics: Animals; Apamin; Blood Pressure; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Serine; Threonine | 2008 |
Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Allopurinol; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrazines; Hypoxia; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxypurinol; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Time Factors; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthine Oxidase | 2009 |
Prefrontal GABA(B) receptor activation attenuates phencyclidine-induced impairments of prepulse inhibition: involvement of nitric oxide.
Topics: Acoustic Stimulation; Animals; Baclofen; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electrochemistry; Enzyme Inhibitors; GABA Agonists; Male; Mice; Mice, Inbred Strains; Neural Inhibition; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phencyclidine; Prefrontal Cortex; Receptors, GABA-B; Reflex, Startle; Signal Transduction | 2009 |
Role of endothelial nitric oxide synthetase in arteriogenesis after stroke in mice.
Topics: Actins; Animals; Carotid Artery, Common; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Ki-67 Antigen; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Neurologic Examination; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroso Compounds; Recovery of Function; Time Factors | 2009 |
Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo.
Topics: Acetylcholine; Animals; Blood Pressure; Calcium Signaling; Carotid Arteries; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; RNA, Messenger; TRPV Cation Channels; Vasodilation; Vasodilator Agents | 2009 |
B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Carotid Arteries; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Superoxides; Tyrosine; Vascular Resistance; Vasodilation; Vasodilator Agents | 2009 |
Physical exercise attenuates the cardiac autonomic deficit induced by nitric oxide synthesis blockade.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atropine Derivatives; Autonomic Nervous System; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Physical Conditioning, Animal; Propranolol; Rats; Rats, Wistar | 2009 |
Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice.
Topics: Analysis of Variance; Animals; Animals, Inbred Strains; Anticonvulsants; Arachidonic Acids; Arginine; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Seizures | 2009 |
Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1.
Topics: Animals; Aorta; Arginine; Atherosclerosis; Atorvastatin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Heme Oxygenase-1; Hemin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Protoporphyrins; Pyrroles; Rabbits; Simvastatin; Time Factors | 2009 |
Balancing role of nitric oxide in complement-mediated activation of platelets from mCd59a and mCd59b double-knockout mice.
Topics: Animals; Blood Platelets; CD59 Antigens; Complement Activation; Complement C3; Complement Membrane Attack Complex; Disease Models, Animal; Hemoglobinuria, Paroxysmal; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Platelet Activation; S-Nitroso-N-Acetylpenicillamine; Thrombophilia | 2009 |
L-arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction.
Topics: Animals; Arginase; Arginine; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Guinea Pigs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Ovalbumin; Perfusion; Peroxynitrous Acid; Polyamines; Polyelectrolytes; Trachea | 2009 |
Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes.
Topics: Amidines; Animals; Body Weight; Crosses, Genetic; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Fetal Resorption; Fetus; Heterocyclic Compounds, 2-Ring; Litter Size; Mice; Mice, Inbred ICR; Mice, Knockout; Neural Tube Defects; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Pregnancy | 2009 |
Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.
Topics: Androstadienes; Anilides; Animals; Blood Glucose; Blotting, Western; Decanoic Acids; Disease Models, Animal; Enzyme Activation; Hemodynamics; Hydroxy Acids; Hypoglycemic Agents; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Pioglitazone; Potassium Channel Blockers; Potassium Channels; PPAR gamma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rabbits; Thiazolidinediones; Time Factors; Ventricular Function, Left; Wortmannin | 2009 |
Cirrhosis ameliorates monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Common Bile Duct; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Hypertension, Pulmonary; Ligation; Liver Cirrhosis, Biliary; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasodilation | 2009 |
The nitric oxide (NO) donor molsidomine antagonizes scopolamine and L-NAME-induced performance deficits in a spatial memory task in the rat.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Memory Disorders; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Rats; Rats, Wistar; Scopolamine; Space Perception | 2009 |
Improvement of renal hemodynamics during hypertension-induced chronic renal disease: role of EGF receptor antagonism.
Topics: Animals; Arterioles; Blood Pressure; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Hypertension; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Quinazolines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasoconstriction | 2009 |
Alteration in male reproductive system in experimental cholestasis: roles for opioids and nitric oxide overproduction.
Topics: Animals; Bile Ducts; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Genitalia, Male; Ligation; Luteinizing Hormone; Male; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Opioid Peptides; Rats; Rats, Sprague-Dawley; Sperm Count; Sperm Motility; Testosterone | 2009 |
Bacterial translocation to kidney in rats with intestinal obstruction and the role of nitric oxide.
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Free Radical Scavengers; Intestinal Obstruction; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Urinary Tract Infections | 2009 |
No evidence for an enhanced role of endothelial nitric oxide in the maintenance of arterial blood pressure in the IUGR sheep fetus.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Female; Fetal Growth Retardation; Fetus; Gestational Age; Humans; Hypertension; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pregnancy; Prenatal Exposure Delayed Effects; Sheep; Vasodilation | 2009 |
The role of nitric oxide in the expression of renal aquaporin 2 in a cirrhotic rat model: does an AVP-independent mechanism exist for the regulation of AQP2 expression?
Topics: Analysis of Variance; Animals; Aquaporin 2; Biopterins; Cyclic GMP; Disease Models, Animal; Immunoenzyme Techniques; Isosorbide Dinitrate; Kidney; Liver Cirrhosis; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Statistics, Nonparametric; Thioacetamide | 2010 |
Effects of chronic treatment with the CB1 antagonist, rimonabant on the blood pressure, and vascular reactivity of obese Zucker rats.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Rate; Indomethacin; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Obesity; Phenylephrine; Piperidines; Pyrazoles; Rats; Rats, Zucker; Receptor, Cannabinoid, CB1; Rimonabant; Vasoconstriction; Vasodilation | 2009 |
Antinociceptive effects of (O-methyl)-N-benzoyl tyramine (riparin I) from Aniba riparia (Nees) Mez (Lauraceae) in mice.
Topics: Acetic Acid; Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Formaldehyde; Hot Temperature; Injections, Intraperitoneal; Lauraceae; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Reaction Time; Time Factors; Tyramine | 2009 |
Plasma-mediated vascular dysfunction in the reduced uterine perfusion pressure model of preeclampsia: a microvascular characterization.
Topics: Analysis of Variance; Animals; Blood Pressure Determination; Disease Models, Animal; Endothelium, Vascular; Female; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Placenta; Pre-Eclampsia; Pregnancy; Pressure; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Uterus; Vasoconstriction; Vasodilation | 2009 |
PPAR-gamma agonist rosiglitazone reverses increased cerebral venous hydraulic conductivity during hypertension.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Brain Edema; Capillary Permeability; Cerebral Veins; Cerebrovascular Circulation; Chronic Disease; Cyclic N-Oxides; Disease Models, Animal; Female; Hydrostatic Pressure; Hypertension; NG-Nitroarginine Methyl Ester; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Spin Labels; Thiazolidinediones; Time Factors | 2009 |
The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions.
Topics: Anesthetics, Inhalation; Animals; Atropine; Baroreflex; Blood Pressure; Bradycardia; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; Hypertension; Isoflurane; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentolinium Tartrate; Pulmonary Edema; Rats; Rats, Wistar; Spinal Cord Injuries; Sympathetic Nervous System; Time Factors; Vasoconstriction | 2009 |
Fenofibrate enhances neovascularization in a murine ischemic hindlimb model.
Topics: Animals; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Fenofibrate; Hindlimb; Hypolipidemic Agents; Ischemia; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Triglycerides | 2009 |
Biomechanical strain causes maladaptive gene regulation, contributing to Alport glomerular disease.
Topics: Adaptation, Physiological; Animals; Blood Pressure; Cells, Cultured; Cytoskeleton; Disease Models, Animal; Gene Expression Regulation; Glomerular Basement Membrane; Hypertension; Interleukin-6; Kidney Glomerulus; Matrix Metalloproteinase 10; Matrix Metalloproteinase 14; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nephritis, Hereditary; NG-Nitroarginine Methyl Ester; Podocytes; Proteinuria; RNA, Messenger; Sodium Chloride, Dietary; Stress, Mechanical; Time Factors | 2009 |
Antioxidants reverse age-related collateral growth impairment.
Topics: Acetophenones; Age Factors; Aging; Animals; Antioxidants; Collateral Circulation; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Ileum; Ligation; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred WKY; Rats, Wistar; RNA, Messenger; Spin Labels | 2010 |
Protective actions of estrogen on angiotensin II-induced hypertension: role of central nitric oxide.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Estrogens; Female; Ganglionic Blockers; Hexamethonium; Hypertension; Immunohistochemistry; Infusion Pumps, Implantable; Infusions, Subcutaneous; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Orchiectomy; Ornithine; Ovariectomy; Paraventricular Hypothalamic Nucleus; Receptors, Estrogen; Sex Factors; Subfornical Organ; Sympathetic Nervous System; Telemetry; Time Factors; Up-Regulation | 2009 |
Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.
Topics: Angiotensin II; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Disease Models, Animal; GABA Agonists; GABA Antagonists; Hypertension; Infusion Pumps, Implantable; Male; Microinjections; Muscimol; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Time Factors; Up-Regulation | 2009 |
Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis.
Topics: Acetylcholine; Animals; Aorta; Atorvastatin; Biological Factors; Blood Cell Count; Blood Pressure; Calcium Channel Blockers; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypotension; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Phenylephrine; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Sepsis; Vasodilation | 2009 |
Superoxide signaling in pain is independent of nitric oxide signaling.
Topics: Animals; Antimycin A; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Male; Metalloporphyrins; Mice; Mice, Inbred C57BL; Neuralgia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Pain Measurement; Peroxynitrous Acid; Reactive Oxygen Species; Signal Transduction; Spin Labels; Superoxides; Tyrosine | 2009 |
Regular exercise produced cardioprotective effects on rat's heart with hypertension induced by L-NAME administration.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Body Weight; Disease Models, Animal; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Physical Conditioning, Animal; Rats | 2009 |
Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome.
Topics: Adipose Tissue; Animals; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Metabolic Syndrome; Mice; Mice, Inbred Strains; Mice, Obese; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Vascular Resistance; Vasculitis | 2009 |
Blood pressure and renal blow flow responses in heme oxygenase-2 knockout mice.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Renal Circulation; Vascular Resistance; Vasoconstriction | 2009 |
The effect of L-arginine and L-NAME on pentylenetetrazole induced seizures in ovariectomized rats, an in vivo study.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Enzyme Inhibitors; Female; NG-Nitroarginine Methyl Ester; Ovariectomy; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2009 |
Endothelial nitric oxide synthase affects both early and late collateral arterial adaptation and blood flow recovery after induction of hind limb ischemia in mice.
Topics: Animals; Chemotaxis; Collateral Circulation; Disease Models, Animal; Enzyme Inhibitors; Gangrene; Hindlimb; Ischemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Receptors, CXCR4; Recovery of Function; Regional Blood Flow; Stem Cells; Time Factors; Toes; Vascular Endothelial Growth Factor Receptor-1 | 2010 |
Sympathetic activity is not increased in L-NAME hypertensive rats.
Topics: Animals; Baroreflex; Blood Pressure; Consciousness; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Rats; Rats, Wistar; Sympathetic Nervous System; Time Factors | 2010 |
Effects of olmesartan on Apelin/APJ and Akt/endothelial nitric oxide synthase pathway in Dahl rats with end-stage heart failure.
Topics: Adipokines; Angiotensin II Type 1 Receptor Blockers; Animals; Apelin; Apelin Receptors; Carrier Proteins; Disease Models, Animal; Down-Regulation; Heart Failure; Imidazoles; Intercellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Dahl; Receptors, G-Protein-Coupled; Signal Transduction; Tetrazoles | 2010 |
Influence of hypercholesterolemia and hypertension on the integrity of the blood-brain barrier in rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood-Brain Barrier; Body Weight; Catalase; Cholesterol; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutathione; Hypercholesterolemia; Hypertension; Lipoproteins, LDL; Male; Malondialdehyde; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphoproteins; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Zonula Occludens-1 Protein | 2009 |
Inhibitory effects of angiotensin-(1-7) on the nerve stimulation-induced release of norepinephrine and neuropeptide Y from the mesenteric arterial bed.
Topics: Angiotensin I; Animals; Antihypertensive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Imidazoles; Male; Mesenteric Arteries; Neuropeptide Y; NG-Nitroarginine Methyl Ester; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Synaptic Transmission | 2010 |
Seizure susceptibility alteration through 5-HT(3) receptor: modulation by nitric oxide.
Topics: Animals; Anticonvulsants; Arginine; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Granisetron; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Piperidines; Receptors, Serotonin, 5-HT3; Seizures; Serotonin Antagonists | 2010 |
Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Arginine; Caffeine; Central Nervous System Stimulants; Chronic Disease; Cyclohexanols; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Random Allocation; Swimming; Venlafaxine Hydrochloride | 2010 |
Phosphodiesterase-5 inhibition by sildenafil citrate in a rat model of bleomycin-induced lung fibrosis.
Topics: Animals; Apoptosis; Bleomycin; Disease Models, Animal; Female; Glutathione; Interleukin-1beta; Lung; Male; Malondialdehyde; Neutrophils; NG-Nitroarginine Methyl Ester; Peroxidase; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Fibrosis; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Tumor Necrosis Factor-alpha | 2010 |
Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis.
Topics: Aconitate Hydratase; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Detergents; Disease Models, Animal; Disease Progression; Electrophoresis, Gel, Two-Dimensional; Humans; Immunohistochemistry; Mice; NG-Nitroarginine Methyl Ester; Protein Structure, Quaternary; Proteins; Proteomics; Reproducibility of Results; Solubility; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord; Stress, Physiological; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine | 2009 |
Influence of pertussis toxin pretreatment on the development of L-NAME-induced hypertension.
Topics: Animals; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Male; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Rats; Rats, Wistar | 2009 |
Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice.
Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Antioxidants; Capsaicin; Disease Models, Animal; Diterpenes; Ethanol; Gastric Mucosa; Glyburide; Indomethacin; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Extracts; Plant Leaves; Plectranthus; Quinones; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbiturates | 2010 |
Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries.
Topics: Acetylcholine; Age Factors; Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hypertrophy; Indomethacin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitrobenzenes; Obesity; Rats; Rats, Zucker; Regional Blood Flow; Splanchnic Circulation; Sulfonamides; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
Sildenafil citrate improves fetal outcomes in pregnant, L-NAME treated, Sprague-Dawley rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Female; Fetal Death; NG-Nitroarginine Methyl Ester; Piperazines; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2010 |
Endothelial nitric oxide synthase activity involves in the protective effect of ascorbic acid against penicillin-induced epileptiform activity.
Topics: Analysis of Variance; Animals; Antioxidants; Arginine; Ascorbic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Free Radical Scavengers; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Penicillins; Rats; Rats, Wistar | 2010 |
An angiotensin II- and NF-kappaB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Binding Sites; Blood Pressure; Carotid Arteries; Cell Line; Connexin 43; Connexins; Disease Models, Animal; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Gap Junction alpha-5 Protein; Genes, Reporter; Hypertension, Renovascular; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Nephrectomy; NF-kappa B; NG-Nitroarginine Methyl Ester; Phosphorylation; Promoter Regions, Genetic; Rats; Renin; Time Factors; Transfection; Up-Regulation | 2010 |
Behavioral, biochemical and cellular correlates in the protective effect of sertraline against transient global ischemia induced behavioral despair: possible involvement of nitric oxide-cyclic guanosine monophosphate study pathway.
Topics: Adult; Animals; Antidepressive Agents; Behavior, Animal; Cell Respiration; Cyclic GMP; Depression; Disease Models, Animal; Enzyme Inhibitors; Humans; Ischemic Attack, Transient; Mice; Motor Activity; Neuroprotective Agents; Neuropsychological Tests; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Random Allocation; Reperfusion Injury; Sertraline | 2010 |
A crucial role of nitric oxide in acute lung injury secondary to the acute necrotizing pancreatitis.
Topics: Acute Lung Injury; Animals; Arginine; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Inflammation Mediators; Injections, Intraperitoneal; Lung; Macrophages, Alveolar; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pancreatitis, Acute Necrotizing; Peroxidase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Taurocholic Acid; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2010 |
Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex.
Topics: Animals; Antigens, Ly; Blood Pressure; CD11b Antigen; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Genetic Predisposition to Disease; Hypertension; Male; Mice; Mice, Congenic; Mice, Inbred BALB C; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; NK Cell Lectin-Like Receptor Subfamily B | 2010 |
Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice.
Topics: Animals; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Freund's Adjuvant; Gene Expression Regulation, Enzymologic; Hyperalgesia; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nociceptors; RNA, Messenger; Sensory Receptor Cells; Tumor Necrosis Factor-alpha | 2010 |
Losartan increases NO release in afferent arterioles during regression of L-NAME-induced renal damage.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Disease Models, Animal; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Hydralazine; Kidney; Kidney Diseases; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstriction | 2010 |
Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Injections, Intraperitoneal; Lithium Chloride; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Treatment Outcome | 2010 |
Nitric oxide synthase mediates the ability of darbepoetin alpha to improve the cognitive performance of STOP null mice.
Topics: Animals; Behavior, Animal; Cognition Disorders; Darbepoetin alfa; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Erythropoietin; Female; Hematinics; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Microtubule-Associated Proteins; NADPH Dehydrogenase; Neuropsychological Tests; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prosencephalon; Recognition, Psychology | 2010 |
Characterization of a model of an arteriovenous fistula in the rat: the effect of L-NAME.
Topics: Animals; Arteriovenous Fistula; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Inflammation; Models, Biological; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Renal Dialysis; Reverse Transcriptase Polymerase Chain Reaction; Thrombosis | 2010 |
Role of nitric oxide in ginsenoside Rg(1)-induced protection against left ventricular hypertrophy produced by abdominal aorta coarctation in rats.
Topics: Abdomen; Animals; Aortic Coarctation; Arginine; Atrial Natriuretic Factor; Cardiovascular Agents; Disease Models, Animal; Endothelium; Ginsenosides; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Panax; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2010 |
Effects of pregnancy, hypertension and nitric oxide inhibition on rat uterine artery myogenic reactivity.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Female; Hydralazine; Hypertension; Hypertension, Pregnancy-Induced; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Rats; Rats, Sprague-Dawley; Time Factors; Uterine Artery; Vasoconstriction; Vasodilation; Vasodilator Agents | 2010 |
[Model of gastroesophageal reflux concomitant with functional constipation in conditions of nitric oxide synthase inhibition].
Topics: Animals; Constipation; Disease Models, Animal; Enzyme Inhibitors; Gastroesophageal Reflux; Gastrointestinal Motility; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 2009 |
Cholestasis induces apoptosis in mice cardiac cells: the possible role of nitric oxide and oxidative stress.
Topics: Animals; Apoptosis; Bile Ducts; Catalase; Cholestasis; Disease Models, Animal; Enzyme Inhibitors; Glutathione Peroxidase; Heart Diseases; Ligation; Lipid Peroxidation; Male; Malondialdehyde; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Superoxide Dismutase | 2010 |
Agmatine enhances the anticonvulsant effect of lithium chloride on pentylenetetrazole-induced seizures in mice: Involvement of L-arginine/nitric oxide pathway.
Topics: Agmatine; Analysis of Variance; Animals; Antidepressive Agents; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Indazoles; Lithium Chloride; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction | 2010 |
Repeated phlebotomy augments angiogenesis to improve blood flow in murine ischemic legs.
Topics: Androstadienes; Animals; Benzylamines; Capillaries; Cyclams; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Erythropoietin; Femoral Artery; Heterocyclic Compounds; Hindlimb; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Ligation; Male; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phlebotomy; Proto-Oncogene Proteins c-akt; Receptors, CXCR4; Regional Blood Flow; Signal Transduction; Stem Cells; Time Factors; Vascular Endothelial Growth Factor A; Wortmannin | 2010 |
Inhibition of nitric oxide synthase in the paraventricular nucleus prevents the hyperthermia-induced reduction of mesenteric blood flow in rats.
Topics: Animals; Blood Pressure; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Fever; Heart Rate; Male; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reflex; Regional Blood Flow; Splanchnic Circulation; Time Factors; Vasoconstriction; Vasodilation | 2010 |
A study of cardiovascular function in Tsumura Suzuki obese diabetes, a new model mouse of type 2 diabetes.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus, Type 2; Disease Models, Animal; Echocardiography; Endothelium, Vascular; Heart; Hyperglycemia; Hyperinsulinism; Hyperlipidemias; Kidney; Male; Mice; Mice, Inbred Strains; Mice, Obese; NG-Nitroarginine Methyl Ester; Obesity; Pancreas; Reference Values; Vasodilation | 2010 |
Beneficial effects of rosuvastatin on aortic adverse remodeling in nitric oxide-deficient rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Endothelial Cells; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Immunohistochemistry; Lipids; Microscopy, Electron, Transmission; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pyrimidines; Rats; Rats, Wistar; Rosuvastatin Calcium; Sulfonamides; Tunica Intima | 2011 |
Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Famotidine; Histamine H2 Antagonists; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer; Piperidines; Prostaglandins; Rats; Rats, Sprague-Dawley | 2010 |
Nitric oxide-independent stimulation of soluble guanylate cyclase reduces organ damage in experimental low-renin and high-renin models.
Topics: Animals; Animals, Genetically Modified; Antihypertensive Agents; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Guanylate Cyclase; Heart; Hypertension; Kidney; Longevity; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Nephrectomy; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrazoles; Pyrimidines; Rabbits; Rats; Rats, Wistar; Renin; Signal Transduction | 2010 |
Prostacyclin and milrinone by aerosolization improve pulmonary hemodynamics in newborn lambs with experimental pulmonary hypertension.
Topics: Administration, Inhalation; Aerosols; Animals; Animals, Newborn; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epoprostenol; Hemodynamics; Hypertension, Pulmonary; Indomethacin; Milrinone; NG-Nitroarginine Methyl Ester; Phosphodiesterase Inhibitors; Pulmonary Circulation; Sheep; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
Enantioselective pharmacokinetic-pharmacodynamic modelling of carvedilol in a N-nitro-l-arginine methyl ester rat model of secondary hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Inactivation, Metabolic; Male; Models, Biological; NG-Nitroarginine Methyl Ester; Propanolamines; Random Allocation; Rats; Rats, Wistar; Stereoisomerism; Sympatholytics | 2010 |
Changes in contractile and electrical activity in the ileum of DSS-induced colitis model W/Wv mutant mice.
Topics: Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Ileum; In Vitro Techniques; Interstitial Cells of Cajal; Male; Mice; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide Synthase Type II | 2010 |
L-NAME-treatment alters ectonucleotidase activities in kidney membranes of rats.
Topics: Adenosine Triphosphatases; Animals; Blood Pressure; Cell Membrane; Chromatography, High Pressure Liquid; Creatinine; Disease Models, Animal; Gene Expression; Heart Rate; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Protective effects of N(G)-nitro-L-arginine methyl ester and metallothioneins on excess nitric oxide toxicity in trinitrobenzene sulfonic acid-induced rat colitis.
Topics: Animals; Blood Cell Count; Bone Marrow; Colitis; Colon; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Intestinal Mucosa; Male; Metallothionein; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Trinitrobenzenesulfonic Acid | 2010 |
Essential role of ER-alpha-dependent NO production in resveratrol-mediated inhibition of restenosis.
Topics: Animals; Carotid Arteries; Carotid Stenosis; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Resveratrol; Secondary Prevention; Stilbenes | 2010 |
A combination antioxidant therapy prevents age-related hearing loss in C57BL/6 mice.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Auditory Threshold; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Glutathione; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Presbycusis; Vitamin B Complex | 2010 |
Endogenous nitric oxide can act as beneficial or deleterious in the hypoxic lung depending on the reoxygenation time.
Topics: Animals; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Hypoxia; Lipid Peroxidation; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 2010 |
High-protein-induced glomerular hyperfiltration is independent of the tubuloglomerular feedback mechanism and nitric oxide synthases.
Topics: Animals; Dietary Proteins; Disease Models, Animal; Enzyme Inhibitors; Feedback, Physiological; Female; Glomerular Filtration Rate; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Receptor, Adenosine A1; Time Factors | 2010 |
Adrenomedullin gene delivery is cardio-protective in a model of chronic nitric oxide deficiency combining pressure overload, oxidative stress and cardiomyocyte hypertrophy.
Topics: Adrenomedullin; Animals; Atrial Natriuretic Factor; Cardiomegaly; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Humans; Myocytes, Cardiac; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pressure; Rats; Superoxide Dismutase | 2010 |
Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.
Topics: Age Factors; Aging; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomyopathies; Collagen; Coronary Circulation; Disease Models, Animal; Echocardiography; Elasticity; Enzyme Inhibitors; Extracellular Matrix; Female; Gene Expression Profiling; Gene Expression Regulation; Genotype; Heart Ventricles; Hemodynamics; Hypertension; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Microscopy, Electron; Microscopy, Video; Myocardium; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenotype; Polymerase Chain Reaction; RNA, Messenger; Telemetry; Ventricular Remodeling | 2010 |
Local and cardiorenal effects of periodontitis in nitric oxide-deficient hypertensive rats.
Topics: Alveolar Bone Loss; Animals; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Heart; Hypertension; Kidney; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Periodontitis; Peroxidase; Radiography; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tyrosine | 2011 |
Involvement of the nitric oxide pathway in the anticonvulsant effect of tramadol on pentylenetetrazole-induced seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; Mice, Inbred Strains; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors; Tramadol | 2010 |
Effects of nitric oxide on the primary bladder afferent activities of the rat with and without intravesical acrolein treatment.
Topics: Acrolein; Administration, Intravesical; Afferent Pathways; Animals; Arginine; Cystitis; Disease Models, Animal; Enzyme Inhibitors; Female; Irritants; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Conduction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2011 |
[Integrated assessment of endothelio- and cardioprotective activity of macrolide antibiotics in nitric oxide deficiency model].
Topics: Animals; Anti-Bacterial Agents; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Endothelium, Vascular; Heart Function Tests; Hypertension; Macrolides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Vasoconstriction | 2010 |
Nitric oxide regulates the repair of injured skeletal muscle.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Proliferation; Collagen; Disease Models, Animal; Gene Expression; Hepatocyte Growth Factor; Immunohistochemistry; Male; Matrix Metalloproteinase 2; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; PAX7 Transcription Factor; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Satellite Cells, Skeletal Muscle; Wound Healing | 2011 |
Upregulation of cyclooxygenase-2 expression in porcine macula densa with chronic nitric oxide synthase inhibition.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Electrolytes; Enzyme Inhibitors; Euthanasia, Animal; Female; Gene Expression Regulation, Enzymologic; Humans; Juxtaglomerular Apparatus; Kidney; Kidney Tubules, Distal; Microdissection; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Protein Isoforms; Rabbits; Renin; RNA, Messenger; Swine; Up-Regulation | 2011 |
The impact of intrarenal nitric oxide synthase inhibition on renal blood flow and function in mild and severe hyperdynamic sepsis.
Topics: Animals; Creatinine; Disease Models, Animal; Female; Hemodynamics; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Renal Circulation; Sepsis; Sheep; Urodynamics | 2011 |
Anticonvulsant effect of celecoxib on pentylenetetrazole-induced convulsion: Modulation by NO pathway.
Topics: Animals; Anticonvulsants; Arginine; Celecoxib; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epilepsy; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pyrazoles; Statistics, Nonparametric; Sulfonamides | 2010 |
Three phases of corporal tracing elicited by electrical field stimulation on rabbit corpus cavernosum smooth muscle in penile perfusion model.
Topics: Animals; Area Under Curve; Cholinesterase Inhibitors; Disease Models, Animal; Electric Stimulation; Isometric Contraction; Male; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Penile Erection; Penis; Physostigmine; Rabbits; Signal Transduction | 2011 |
Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats.
Topics: Acetophenones; Anilides; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Hyperalgesia; Lysophospholipids; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Organophosphonates; Oxadiazoles; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Lysosphingolipid; Sphingosine; Thiophenes; Time Factors | 2011 |
Down-regulation of NF-κB signalling by polyphenolic compounds prevents endotoxin-induced liver injury in a rat model.
Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Endotoxins; Female; Humans; Liver Diseases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Polyphenols; Quercetin; Rats; Rats, Wistar; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha | 2012 |
Olprinone attenuates excessive shear stress through up-regulation of endothelial nitric oxide synthase in a rat excessive hepatectomy model.
Topics: Animals; Apoptosis; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Hepatectomy; Hepatocytes; Imidazoles; Immunohistochemistry; In Situ Nick-End Labeling; Infusions, Parenteral; Liver; Liver Circulation; Liver Failure; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphodiesterase 3 Inhibitors; Portal Pressure; Pyridones; Rats; Rats, Inbred Lew; Stress, Mechanical; Time Factors; Up-Regulation | 2011 |
Skeletal muscle arteriolar function following myocardial infarction: Analysis of branch-order effects.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Female; Heart Rate; Muscle Contraction; Muscle, Skeletal; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Vasodilation; Ventricular Dysfunction, Left | 2011 |
Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways.
Topics: Abietanes; Amino Acid Transport Systems, Basic; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Arginine; Benzofurans; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Cells, Cultured; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Time Factors; Vasodilation | 2011 |
Rb1 postconditioning attenuates liver warm ischemia-reperfusion injury through ROS-NO-HIF pathway.
Topics: Animals; Blotting, Western; Body Temperature; Disease Models, Animal; Ginsenosides; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Ischemic Postconditioning; Liver; Liver Function Tests; Male; Mice; Mice, Inbred BALB C; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury | 2011 |
Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Brain Edema; Brain Injuries; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; K Cl- Cotransporters; NG-Nitroarginine Methyl Ester; Percussion; Rats; RNA, Messenger; RNA, Small Interfering; Symporters; Time Factors; Transfection | 2011 |
Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions.
Topics: Animals; Antipsychotic Agents; Capillary Permeability; Dinoprostone; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Glyburide; Hexosamines; Indomethacin; KATP Channels; Ketanserin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Risperidone; Stomach Ulcer; Stress, Physiological; Sulfhydryl Compounds; Sulpiride | 2011 |
Cytosolic phospholipase A2alpha contributes to blood pressure increases and endothelial dysfunction under chronic NO inhibition.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Bone Marrow Transplantation; Disease Models, Animal; Dose-Response Relationship, Drug; Eicosanoids; Endothelium, Vascular; Enzyme Inhibitors; Group IV Phospholipases A2; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Renin; Time Factors; Tissue Culture Techniques; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2011 |
Atorvastatin improved scopolamine-induced impairment in memory acquisition in mice: involvement of nitric oxide.
Topics: Animals; Arginine; Atorvastatin; Cholinergic Antagonists; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Heptanoic Acids; Learning Disabilities; Memory; Memory Disorders; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyrroles; Scopolamine | 2011 |
Role of neuronal nitric oxide synthase in colonic distension-induced hyperalgesia in distal colon of neonatal maternal separated male rats.
Topics: Animals; Animals, Newborn; Colon; Colonic Diseases; Disease Models, Animal; Electromyography; Gastrointestinal Motility; Hyperalgesia; Indazoles; Irritable Bowel Syndrome; Male; Maternal Behavior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2011 |
Long-term administration of BAY 41-2272 prevents bladder dysfunction in nitric oxide-deficient rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pressure; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Time Factors; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urodynamics | 2011 |
Morphine sensitization in the pentylenetetrazole-induced clonic seizure threshold in mice: role of nitric oxide and μ receptors.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Receptors, Opioid, mu; Seizures | 2011 |
Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia.
Topics: Analysis of Variance; Animals; Biopterins; Calcium; Disease Models, Animal; Enzyme Inhibitors; GTP Cyclohydrolase; Humans; Hyperglycemia; Ischemic Preconditioning, Myocardial; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Time Factors; Ultrasonography; Ventricular Function, Left | 2011 |
WT-1 mRNA expression is modulated by nitric oxide availability and Hsp70 interaction after neonatal unilateral ureteral obstruction.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Line; Disease Models, Animal; Dogs; Enzyme Inhibitors; Epithelial Cells; Female; Fluorobenzenes; HSP70 Heat-Shock Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Luminol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Oligopeptides; Pyrimidines; Rats; Rats, Inbred WKY; Rosuvastatin Calcium; Sulfonamides; Tumor Suppressor Protein p53; Ureteral Obstruction; WT1 Proteins | 2010 |
Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats.
Topics: Animals; Antioxidants; Cyclohexenes; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Fatty Liver; Insulin; Insulin Resistance; Insulin Secretion; Limonene; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Metabolic Syndrome; NG-Nitroarginine Methyl Ester; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Pancreas; Random Allocation; Rats; Rats, Wistar; Terpenes | 2012 |
Prenatal brain damage in preeclamptic animal model induced by gestational nitric oxide synthase inhibition.
Topics: Analysis of Variance; Animals; Apoptosis; Blood Pressure; Brain; Crown-Rump Length; Disease Models, Animal; Female; Fetal Diseases; Hypoxia, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Size; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar | 2011 |
Activation of NAD(P)H:quinone oxidoreductase ameliorates spontaneous hypertension in an animal model via modulation of eNOS activity.
Topics: Acetylcholine; AMP-Activated Protein Kinases; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Humans; Hypertension; Male; Mice; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; RNA Interference; Time Factors; Transfection; Vasodilation; Vasodilator Agents | 2011 |
Evaluation of anti-migraine potential of Areca catechu to prevent nitroglycerin-induced delayed inflammation in rat meninges: possible involvement of NOS inhibition.
Topics: Animals; Anti-Inflammatory Agents; Areca; Blood Proteins; Disease Models, Animal; Dura Mater; Enzyme Inhibitors; Female; Macrophages; Male; Meningitis; Mice; Mice, Inbred Strains; Migraine Disorders; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitroglycerin; Nuts; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Spleen | 2011 |
Aortic stiffness in vivo in hypertensive rat via echo-tracking: analysis of the pulsatile distension waveform.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium Channel Blockers; Compliance; Diltiazem; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulsatile Flow; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Processing, Computer-Assisted; Time Factors; Ultrasonography | 2011 |
[Effect of soft tissue crush injury on tensions of thoracic aortic rings in rats].
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Endothelium, Vascular; Female; Hindlimb; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Soft Tissue Injuries; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2011 |
L-NAME and L-arginine differentially ameliorate cigarette smoke-induced emphysema in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Male; Mice; Mice, Inbred C57BL; Neutrophils; NG-Nitroarginine Methyl Ester; Nicotiana; Nitric Oxide; Oxidants; Oxidative Stress; Pulmonary Emphysema; Smoke; Smoking | 2011 |
The preventive effect of N-nitro L-arginine methyl ester in experimentally induced myringosclerosis.
Topics: Administration, Topical; Animals; Biopsy, Needle; Disease Models, Animal; Ear Diseases; Female; Immunohistochemistry; Injections, Intraperitoneal; Male; Myringoplasty; NG-Nitroarginine Methyl Ester; Otoscopy; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Reference Values; Risk Assessment; Sclerosis; Statistics, Nonparametric; Tympanic Membrane | 2011 |
The acute effects of mirtazapine on pain related behavior in healthy animals.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Arginine; Behavior, Animal; Cyproheptadine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Hippocampus; In Vitro Techniques; Male; Mianserin; Mice; Mirtazapine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 2011 |
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
Topics: Adenosine; Animals; Cardiotonic Agents; Cilostazol; Decanoic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Hydroxy Acids; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion Injury; Superoxides; Tetrazoles; Theophylline | 2011 |
Eicosapentaenoic acid reduces the pulmonary vein arrhythmias through nitric oxide.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eicosapentaenoic Acid; Electrophysiology; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Veins; Rabbits | 2011 |
Distribution of the activity of the angiotensin-converting enzyme in the rat aorta and changes in the activity with aging and by the action of L-NAME.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Aorta; Aorta, Thoracic; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelium, Vascular; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Wistar; Reference Values | 2012 |
The interactions of nitric oxide and adenosine on penicillin-induced epileptiform activity in rats.
Topics: Action Potentials; Adenosine; Animals; Brain Waves; Disease Models, Animal; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillins; Rats; Rats, Wistar; Theophylline | 2011 |
Protective effects of hydrogen-rich saline in preeclampsia rat model.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Fetal Resorption; Hydrogen; Interleukin-1beta; Malondialdehyde; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Proteinuria; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Tumor Necrosis Factor-alpha | 2011 |
Detection of intrarenal microstructural changes with supersonic shear wave elastography in rats.
Topics: Animals; Disease Models, Animal; Elasticity; Elasticity Imaging Techniques; Fibrosis; Glomerulosclerosis, Focal Segmental; Image Processing, Computer-Assisted; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 2012 |
Effects of pioglitazone and rosiglitazone on vascular function of mesenteric resistance arteries in rat genetic hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Epinephrine; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Hypoglycemic Agents; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rosiglitazone; Thiazolidinediones; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Augmented central nitric oxide production inhibits vasopressin release during hemorrhage in acute alcohol-intoxicated rodents.
Topics: Alcoholic Intoxication; Animals; Arginine Vasopressin; Blood Pressure; Blood Volume; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Hemorrhage; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Osmolar Concentration; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Signal Transduction; Supraoptic Nucleus; Time Factors; Up-Regulation | 2011 |
Cilostazol stimulates revascularisation in response to ischaemia via an eNOS-dependent mechanism.
Topics: Angiogenesis Inducing Agents; Animals; Blotting, Western; Capillaries; Cilostazol; Disease Models, Animal; Hindlimb; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphodiesterase 3 Inhibitors; Platelet Endothelial Cell Adhesion Molecule-1; Tetrazoles; Time Factors | 2012 |
Impact of L-NAME on the cardiopulmonary reflex in cardiac hypertrophy.
Topics: Animals; Baroreflex; Blood Pressure; Blood Volume; Caffeine; Cardiomegaly; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Heart Rate; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Sympathetic Nervous System; Thyroxine; Urodynamics | 2011 |
Early life stress enhances angiotensin II-mediated vasoconstriction by reduced endothelial nitric oxide buffering capacity.
Topics: Angiotensin II; Animals; Animals, Newborn; Aorta, Thoracic; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Maternal Deprivation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Signal Transduction; Stress, Physiological; Vasoconstriction | 2011 |
Renoprotective effects of combined endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 in acute and chronic experimental renal damage.
Topics: Acute Kidney Injury; Albuminuria; Animals; Aspartic Acid Endopeptidases; Constriction; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glomerulosclerosis, Focal Segmental; Hypertension; Kidney; Kidney Failure, Chronic; Male; Metalloendopeptidases; Nephrectomy; Neprilysin; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Reperfusion Injury | 2011 |
Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction.
Topics: Administration, Oral; Angiogenesis Inducing Agents; Animals; Biopterins; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; GTP Cyclohydrolase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pterins; Recovery of Function; Stroke Volume; Time Factors; Tyrosine; Ultrasonography; Ventricular Function, Left | 2011 |
Inducible nitric oxide synthase (iNOS) and α-melanocyte-stimulating hormones of iNOS origin play important roles in the allergic reactions of atopic dermatitis in mice.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Dermatitis, Atopic; Disease Models, Animal; Enzyme Inhibitors; Histamine; Immunoglobulin E; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Ovalbumin; Pruritus; Skin; Transforming Growth Factor beta; Tryptases; Tumor Necrosis Factor-alpha | 2011 |
Carotid body remodelling in l-NAME-induced hypertension in the rat.
Topics: Animals; Biogenic Amines; Biomarkers; Blood Pressure; Carotid Body; Cell Nucleus; Disease Models, Animal; Enzyme Inhibitors; Fibrillar Collagens; Hypertension; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Proteoglycans; Rats; Rats, Wistar; Substance P; Vascular Endothelial Growth Factor A | 2012 |
Betulinic acid ameliorates endothelium-dependent relaxation in L-NAME-induced hypertensive rats by reducing oxidative stress.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Betulinic Acid; Data Interpretation, Statistical; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pentacyclic Triterpenes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Triterpenes; Vasodilation | 2011 |
The evaluation of hypoxia-inducible factor 1 in N-nitro-L-arginine methyl ester preeclampsia model of pregnant rats.
Topics: Animals; Blood Pressure; Body Weight; Diastole; Disease Models, Animal; Female; Fetus; Humans; Hypoxia-Inducible Factor 1; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Proteinuria; Rats; Rats, Wistar; Systole; Trophoblasts | 2011 |
Effect of nitric oxide in protective effect of melatonin against chronic constriction sciatic nerve injury induced neuropathic pain in rats.
Topics: Animals; Antioxidants; Arginine; Catalase; Chronic Disease; Disease Models, Animal; Glutathione; Hyperalgesia; Lipid Peroxidation; Male; Melatonin; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve | 2011 |
[Effects of nitric oxide synthase inhibitor on hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury].
Topics: Animals; Body Weight; Disease Models, Animal; Eating; Enzyme Inhibitors; Hindlimb; Male; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Atrophy; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley | 2011 |
Effects of Rut-bpy (Cis-[Ru(bpy)2(SO3)(NO)]PF 6), a novel nitric oxide donor, in L-NAME-induced hypertension in rats.
Topics: Anesthesia; Animals; Blood Pressure; Coordination Complexes; Disease Models, Animal; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Organometallic Compounds; Random Allocation; Rats; Rats, Wistar; Ruthenium; Treatment Outcome; Vasodilator Agents | 2011 |
Mitochondrial nitric oxide synthase participates in septic shock myocardial depression by nitric oxide overproduction and mitochondrial permeability transition pore opening.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Indazoles; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Muscle Proteins; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Septic | 2012 |
Inhaled nitric oxide aggravates phosgene model of acute lung injury.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Irritants; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosgene; Plethysmography, Whole Body; Proteins; Pyruvates; Rats; Rats, Wistar | 2011 |
Inhibition of nitric oxide synthase lowers fatty acid oxidation in preeclampsia-like mice at early gestational stage.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Fatty Acids; Female; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidation-Reduction; Pre-Eclampsia; Pregnancy | 2011 |
Beneficial effects of Acer okamotoanum sap on L-NAME-induced hypertension-like symptoms in a rat model.
Topics: Acer; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Plant Preparations; Potassium; Rats; Rats, Sprague-Dawley; Water | 2012 |
Arteriolar insulin resistance in a rat model of polycystic ovary syndrome.
Topics: Acetylcholine; Animals; Arterioles; Blood Glucose; Cholecalciferol; Dihydrotestosterone; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose Tolerance Test; Insulin; Insulin Resistance; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2012 |
A possible role to nitric oxide in the anti-inflammatory effects of amitriptyline.
Topics: Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Cytokines; Disease Models, Animal; Edema; Enzyme Inhibitors; Inflammation; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peritonitis; Rats; Rats, Sprague-Dawley; Skin Diseases | 2012 |
Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Body Weight; Collagen; Disease Models, Animal; Hydroxyproline; Hypertension; Imidazoles; Male; NG-Nitroarginine Methyl Ester; Olmesartan Medoxomil; Pulsatile Flow; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonamides; Tetrazoles; Thiophenes; Vascular Stiffness | 2012 |
Blunted blood pressure response and elevated plasma adiponectin levels in female Sprague Dawley rats.
Topics: Adiponectin; Animals; Blood Pressure; Disease Models, Animal; Female; Fructose; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sodium Chloride, Dietary; Stress, Physiological; Testosterone | 2012 |
The effect of Kraussianone-2 (Kr2), a natural pyrano-isoflavone from Eriosema kraussianum, in an L-NAME- induced pre-eclamptic rat model.
Topics: Animals; Birth Weight; Blood Pressure; Disease Models, Animal; Endoglin; Fabaceae; Female; Intracellular Signaling Peptides and Proteins; Isoflavones; NG-Nitroarginine Methyl Ester; Nitric Oxide; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Pregnancy Proteins; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2012 |
Short-term ACE inhibition confers long-term protection against target organ damage.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Proliferation; Creatinine; Disease Models, Animal; Enalapril; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Urea | 2012 |
[Interaction of fatty acid oxidation with oxidative stress in preeclampsia-like mouse model at multiple stages of gestation].
Topics: Animals; Disease Models, Animal; Fatty Acids; Female; Humans; Lipid Metabolism; Mice; NG-Nitroarginine Methyl Ester; Oxidation-Reduction; Oxidative Stress; Pre-Eclampsia; Pregnancy | 2011 |
Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the PI3K/Akt pathway.
Topics: Analysis of Variance; Animals; Avoidance Learning; Brain; Brain Infarction; Brain Ischemia; Cell Death; Chromones; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; In Situ Nick-End Labeling; Ischemic Postconditioning; Male; Maze Learning; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitroarginine; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinase; Rats; Rats, Sprague-Dawley; Reaction Time; Reperfusion Injury | 2012 |
Protective effects of acute lithium preconditioning against renal ischemia/reperfusion injury in rat: role of nitric oxide and cyclooxygenase systems.
Topics: Animals; Antimanic Agents; Disease Models, Animal; Indomethacin; Ischemic Preconditioning; Kidney; Lithium Chloride; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2012 |
Effect of veratric acid on the cardiovascular risk of L-NAME-induced hypertensive rats.
Topics: Animals; Blood Pressure; Cardiovascular Diseases; Cholesterol, HDL; Disease Models, Animal; Heart Rate; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Hypertension; Kidney; Lipid Metabolism; Lipids; Lipoproteins; Liver; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Risk Factors; Vanillic Acid | 2012 |
Sub-chronic treatment with pioglitazone exerts anti-convulsant effects in pentylenetetrazole-induced seizures of mice: The role of nitric oxide.
Topics: Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pioglitazone; Seizures; Thiazolidinediones | 2012 |
Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins.
Topics: alpha 1-Antitrypsin; Animals; Antithrombins; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Factor Xa; Factor Xa Inhibitors; Factor XIa; Factor XIIa; Ferric Compounds; Fibrinogen; Fibrinolytic Agents; Hemorrhage; Injections, Intravenous; Kinetics; Leukocyte Elastase; Mice; Mutation; NG-Nitroarginine Methyl Ester; Recombinant Fusion Proteins; Thrombin; Thrombosis | 2012 |
Effects of sildenafil in Nω-nitro-L-arginine methyl ester-induced intrauterine growth restriction in a rat model.
Topics: Animals; Birth Weight; Disease Models, Animal; Female; Fetal Growth Retardation; NG-Nitroarginine Methyl Ester; Piperazines; Pre-Eclampsia; Pregnancy; Proteinuria; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2012 |
Chronic administration of atorvastatin induced anti-convulsant effects in mice: the role of nitric oxide.
Topics: Analysis of Variance; Animals; Anticonvulsants; Atorvastatin; Convulsants; Disease Models, Animal; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Guanidines; Heptanoic Acids; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pyrroles; Seizures; Time Factors | 2012 |
Nitric oxide facilitates delivery and mediates improved outcome of autologous bone marrow mononuclear cells in a rodent stroke model.
Topics: Animals; Bone Marrow Transplantation; Cerebrovascular Circulation; Disease Models, Animal; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Rats; Stroke; Time Factors; Transplantation, Autologous; Treatment Outcome | 2012 |
Evaluation of antiulcer activity of chromanone fraction from Calophyllum brasiliesnse Camb.
Topics: Animals; Anti-Ulcer Agents; Calophyllum; Catalase; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromones; Cytoprotection; Disease Models, Animal; Disk Diffusion Antimicrobial Tests; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Helicobacter pylori; Hexanes; Indomethacin; Male; Malondialdehyde; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Rats; Rats, Wistar; Solvents; Stomach Ulcer | 2012 |
Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renal; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley | 2012 |
Insulin induces the correlation between renal blood flow and glomerular filtration rate in diabetes: implications for mechanisms causing hyperfiltration.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Glomerular Filtration Rate; Insulin; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Streptozocin | 2012 |
Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Hypertension; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Vasodilation | 2012 |
In vivo participation of nitric oxide in hyperproliferative epidermal phenomena in mice.
Topics: Acetylglucosaminidase; Animals; Anti-Inflammatory Agents; Cell Proliferation; Croton Oil; Dermatitis, Contact; Dexamethasone; Disease Models, Animal; Enzyme Inhibitors; Epidermis; Guanidines; Indazoles; Keratinocytes; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitroprusside; Peroxidase | 2012 |
The relaxant effect of ginseng saponin on the bladder and prostatic urethra: an in vitro and in vivo study.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Panax; Phenylephrine; Plant Extracts; Plant Roots; Pressure; Prostatic Hyperplasia; Rabbits; Rats; Rats, Sprague-Dawley; Saponins; Urethra; Urinary Bladder; Urinary Bladder Neck Obstruction; Urodynamics | 2012 |
Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism.
Topics: Administration, Oral; Animals; Aorta; Cardiovascular Agents; Carotid Arteries; Carotid Artery Injuries; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Femoral Artery; Gene Expression Regulation; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Neointima; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Time Factors; Vascular System Injuries | 2012 |
Protective role of nitric oxide induced by ischemic preconditioning on cold ischemic-reperfusion injury of rat liver graft.
Topics: Adenosine; Alanine Transaminase; Animals; Anticoagulants; Apoptosis; Bile; Cold Ischemia; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Heparin; Ischemic Preconditioning; Liver; Liver Transplantation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Superoxides; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
The antiproteinuric effects of green tea extract on acute cyclosporine-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Catalase; Cyclosporine; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Kidney; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Proteinuria; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tea | 2012 |
Effects of nitric oxide on renal interstitial fibrosis in rats with unilateral ureteral obstruction.
Topics: Animals; Arginine; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Ureteral Obstruction; Vascular Endothelial Growth Factor A | 2012 |
A role for nitric oxide within the nucleus tractus solitarii in the development of muscle mechanoreflex dysfunction in hypertension.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; Hexamethonium; Hypertension; Male; Mechanotransduction, Cellular; Microdialysis; Muscle Spindles; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex, Stretch; Solitary Nucleus; Time Factors | 2012 |
Effect of selective inhibition of renal inducible nitric oxide synthase on renal blood flow and function in experimental hyperdynamic sepsis.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Female; Guanidines; Hemodynamics; Infusions, Intra-Arterial; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Renal Artery; Renal Circulation; Sepsis; Sheep | 2012 |
Long-lasting hypotensive effect in renal hypertensive rats induced by nitric oxide released from a ruthenium complex.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Hypertension, Renovascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Rats; Ruthenium Compounds; Spin Labels; Time Factors | 2012 |
Late-life enalapril administration induces nitric oxide-dependent and independent metabolic adaptations in the rat skeletal muscle.
Topics: Adaptation, Physiological; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Energy Metabolism; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred BN; Rats, Inbred F344 | 2013 |
Role of specific T-type calcium channel blocker R(-) efonidipine in the regulation of renal medullary circulation.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Calcium Channel Blockers; Calcium Channels, T-Type; Dihydropyridines; Disease Models, Animal; Drug Antagonism; Infusions, Intravenous; Ischemia; Kidney Medulla; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitrogen Dioxide; Nitrogen Oxides; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstrictor Agents | 2012 |
Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling.
Topics: Acetylcholinesterase; Animals; Arterioles; Atropine; Calcium; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; HSP90 Heat-Shock Proteins; Male; Mecamylamine; Methysergide; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reperfusion; Selective Serotonin Reuptake Inhibitors; Serotonin; Signal Transduction; Stroke; Vasodilation | 2012 |
Changes in optic nerve head circulation in response to vasoactive agents: intereye comparison in monkeys with experimental unilateral glaucoma.
Topics: Animals; Arginine; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Disease Models, Animal; Enzyme Inhibitors; Female; Glaucoma; Intraocular Pressure; Lasers, Gas; Macaca fascicularis; NG-Nitroarginine Methyl Ester; Nifedipine; Optic Disk; Piperazines; Regional Blood Flow; Tonometry, Ocular; Trabecular Meshwork | 2012 |
Mesenteric arteries responsiveness to acute variations of wall shear stress is impaired in rats with liver cirrhosis.
Topics: Animals; Carbon Tetrachloride; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Indomethacin; Liver Cirrhosis; Male; Mesenteric Arteries; Mesoporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Wistar; Regional Blood Flow; Splanchnic Circulation; Statistics, Nonparametric; Stress, Mechanical; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2012 |
Hepatoprotective and anti-inflammatory effects of silibinin on experimental preeclampsia induced by L-NAME in rats.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunologic Factors; Inflammation; Liver; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Protective Agents; Rats; Rats, Wistar; Silybin; Silymarin | 2012 |
Protective effect of nitric oxide on hepatopulmonary syndrome from ischemia-reperfusion injury.
Topics: Alanine Transaminase; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Hepatorenal Syndrome; Immunohistochemistry; Intercellular Adhesion Molecule-1; Liver; Liver Transplantation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
[Involvement of NO-dependent mechanisms of apelin action in myocardial protection against ischemia/reperfusion damage].
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Intercellular Signaling Peptides and Proteins; Male; Models, Cardiovascular; Monitoring, Physiologic; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Signal Transduction | 2012 |
Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Genistein; Glutathione; Guanidines; Hydroxyproline; Isoproterenol; Male; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Quantification of utero-placental vascularization in a rabbit model of IUGR with three-dimensional power Doppler angiography.
Topics: Animals; Disease Models, Animal; Female; Fetal Growth Retardation; Imaging, Three-Dimensional; NG-Nitroarginine Methyl Ester; Placenta; Placental Circulation; Pregnancy; Rabbits; Ultrasonography | 2012 |
The differential role of NOS inhibitors on stress-induced anxiety and neuroendocrine alterations in the rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Brain; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Indazoles; Male; Maze Learning; NADP; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Reaction Time; Restraint, Physical | 2012 |
The involvement of nitric oxide in the anti-seizure effect of acute atorvastatin treatment in mice.
Topics: Animals; Anticonvulsants; Atorvastatin; Brain; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Enzyme Inhibitors; Epilepsy, Tonic-Clonic; Guanidines; Heptanoic Acids; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pyrroles | 2012 |
Muscimol delays lipopolysaccharide-induced preterm delivery in mice: role of GABA(A) receptors and nitric oxide.
Topics: Amniotic Fluid; Animals; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Lipopolysaccharides; Mice; Muscimol; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Placenta; Pregnancy; Premature Birth; Receptors, GABA-A; Uterine Contraction | 2013 |
Reduction of nitric oxide-mediated γ-amino butyric acid release in rostral ventrolateral medulla is involved in superoxide-induced sympathoexcitation of hypertensive rats.
Topics: Animals; Arterial Pressure; Bicuculline; Cyclic N-Oxides; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Kidney; Kynurenic Acid; Male; Medulla Oblongata; Microdialysis; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Superoxides; Sympathetic Nervous System; Time Factors | 2012 |
Antihypertensive and cardioprotective effects of the Lagenaria siceraria fruit in NG-nitro-L-arginine methyl ester (L-NAME) induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Apigenin; Blood Pressure; Cardiotonic Agents; Cholesterol; Chromatography, High Pressure Liquid; Cucurbitaceae; Disease Models, Animal; Flavonoids; Fruit; Glucosides; Hypertension; Inflammation; Luteolin; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Rats, Wistar | 2012 |
Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure.
Topics: Age Factors; Animals; Animals, Newborn; Aorta; Arginine; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hyperoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Pterins; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilation; Vasodilator Agents | 2013 |
Effect of treadmill exercise and Ferula gummosa on myocardial HSP72, vascular function, and antioxidant defenses in spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Biomarkers; Cardiovascular System; Disease Models, Animal; Ferula; Glutathione Reductase; HSP72 Heat-Shock Proteins; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Plant Extracts; Protein Carbonylation; Rats; Rats, Wistar | 2013 |
Syringic acid ameliorates (L)-NAME-induced hypertension by reducing oxidative stress.
Topics: Animals; Antioxidants; Biomarkers; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Gallic Acid; Hypertension; Kidney Function Tests; Lipid Peroxidation; Liver Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar | 2012 |
Effects of taxifolin on the activity of angiotensin-converting enzyme and reactive oxygen and nitrogen species in the aorta of aging rats and rats treated with the nitric oxide synthase inhibitor and dexamethasone.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Atherosclerosis; Dexamethasone; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Glucocorticoids; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrogen; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species | 2013 |
Altered expression of nNOS/NIDD in the retina of a glaucoma model of DBA/2J mice and the intervention by nNOS inhibition.
Topics: Age Factors; Animals; Apoptosis; Carrier Proteins; Disease Models, Animal; Enzyme Inhibitors; Ependymoglial Cells; Glaucoma; Membrane Proteins; Mice; Mice, Inbred DBA; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Optic Nerve; Retinal Ganglion Cells; RNA, Messenger | 2013 |
Basal release of nitric oxide in the mesenteric artery in portal hypertension and cirrhosis: role of dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Endothelium, Vascular; Hypertension, Portal; In Vitro Techniques; Liver Cirrhosis, Experimental; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Vasodilation | 2013 |
Oxidative stress contributes to endothelial dysfunction in mouse models of hereditary hemorrhagic telangiectasia.
Topics: Activin Receptors, Type I; Activin Receptors, Type II; Animals; Disease Models, Animal; Endoglin; Endothelium, Vascular; Heterozygote; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondria; Models, Biological; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Telangiectasia, Hereditary Hemorrhagic | 2012 |
Involvement of the nitric oxide/cyclic guanylate monophosphate pathway in the pilocarpine-induced seizure model in mice.
Topics: Amidines; Animals; Arginine; Benzylamines; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Guanylate Cyclase; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pilocarpine; Receptors, Cytoplasmic and Nuclear; Seizures; Soluble Guanylyl Cyclase | 2013 |
Tempol selectively attenuates angiotensin II evoked vasoconstrictor responses in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Luminescent Measurements; Male; Mesenteric Arteries; Models, Cardiovascular; NG-Nitroarginine Methyl Ester; Perfusion; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Spin Labels; Superoxides; Vasoconstriction | 2002 |
The effects of topical L-arginine and Ng-nitro-L-arginine methyl ester after experimental acute spinal cord injury. A light and electron microscopic study.
Topics: Administration, Topical; Animals; Arginine; Blood Flow Velocity; Disease Models, Animal; Enzyme Inhibitors; Male; Microscopy; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Rabbits; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries; Spinal Cord Ischemia | 2002 |
Effect of inhibition of inducible nitric oxide synthase and guanylyl cyclase on endotoxin-induced delay in gastric emptying and intestinal transit in mice.
Topics: Animals; Dexamethasone; Disease Models, Animal; Endotoxins; Female; Gastric Emptying; Gastrointestinal Transit; Guanylate Cyclase; Intestinal Obstruction; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Reference Values; Sensitivity and Specificity | 2002 |
[The influence of nitric synthase inhibitor (L-NAME) on the intraocular pressure in endotoxin induced uveitis in rats].
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Enzyme Inhibitors; Female; Intraocular Pressure; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Time Factors; Uveitis | 2002 |
Alterations of intestinal motor responsiveness in a model of mild mesenteric ischemia/reperfusion in rats.
Topics: Acetylcholine; Animals; Chymotrypsin; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Gastrointestinal Motility; Ileum; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reperfusion Injury | 2002 |
Role of oxygen and nitrogen species in experimental uveitis: anti-inflammatory activity of the synthetic antioxidant ebselen.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Azoles; Chlorpromazine; Disease Models, Animal; Enzyme Inhibitors; Free Radicals; Isoindoles; Lipid Peroxidation; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organoselenium Compounds; Rabbits; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase; Uveitis | 2002 |
Chronic alpha1-adrenergic blockade improves hypertension and renal injury in L-NAME and low-renin L-NAME-DOCA hypertensive rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Desoxycorticosterone; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renal; Kidney; Kidney Diseases; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Renin; Time Factors | 2002 |
Hypertension plus diabetes mimics the cardiomyopathy induced by nitric oxide inhibition in rats.
Topics: Analysis of Variance; Animals; Blotting, Western; Cardiomyopathy, Hypertrophic; Diabetes Mellitus, Experimental; Disease Models, Animal; Hypertension, Renovascular; Immunohistochemistry; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Probability; Random Allocation; Rats; Rats, Wistar; Streptozocin | 2002 |
Antiinflammatory and antiarteriosclerotic effects of pioglitazone.
Topics: Animals; Anti-Inflammatory Agents; Arteriosclerosis; Blood Glucose; Blood Pressure; Chemokine CCL2; Coronary Artery Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Inflammation; Insulin; Lipids; Male; Monocytes; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Pioglitazone; Rats; Rats, Inbred WKY; Receptors, CCR2; Receptors, Chemokine; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome | 2002 |
Oral L-arginine prevents murine coxsackievirus B3 myocarditis.
Topics: Administration, Oral; Animals; Arginine; Coxsackievirus Infections; Disease Models, Animal; Enterovirus B, Human; Enzyme Inhibitors; Male; Mice; Mice, Inbred C3H; Myocarditis; NG-Nitroarginine Methyl Ester; Severity of Illness Index; Survival Rate | 2002 |
Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study.
Topics: Animals; Disease Models, Animal; Hydralazine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyridines; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling | 2002 |
Endothelin-A receptor blockade in porcine pulmonary hypertension.
Topics: Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; NG-Nitroarginine Methyl Ester; Oligopeptides; Oxygen; Pulmonary Circulation; Receptor, Endothelin A; Streptococcal Infections; Streptococcus agalactiae; Sus scrofa; Thiazoles | 2002 |
L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Brain Ischemia; Disease Models, Animal; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Male; Mice; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2002 |
Effect of NO synthase inhibition on cardiovascular and pulmonary dysfunction in a porcine short-term model of endotoxic shock.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Central Venous Pressure; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli; Guanidines; Heart Rate; Hemodynamics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen Consumption; Respiration; Shock, Septic; Swine; Time Factors; Vascular Resistance | 2002 |
[Comparison of the effects of NG-monomethyl-L-arginine and indomethacin on tuberculous arthritis: an experimental study in rats].
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Disease Models, Animal; Enzyme Inhibitors; Indomethacin; Injections, Intraperitoneal; Knee Joint; Male; NG-Nitroarginine Methyl Ester; Radionuclide Imaging; Random Allocation; Rats; Rats, Wistar; Tuberculosis, Osteoarticular | 2002 |
Effects of omapatrilat on blood pressure and renal injury in L-NAME and L-NAME plus DOCA-treated rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Creatinine; Desoxycorticosterone; Disease Models, Animal; Drinking; Eating; Enzyme Inhibitors; Hypertension, Renal; Kidney; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Potassium; Pyridines; Rats; Rats, Wistar; Sodium; Thiazepines; Urea | 2003 |
Role of opioid and nitric oxide systems in the nonadrenergic noncholinergic-mediated relaxation of corpus cavernosum in bile duct-ligated rats.
Topics: Animals; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Opioid Peptides; Penis; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Partial volume rat lung irradiation; assessment of early DNA damage in different lung regions and effect of radical scavengers.
Topics: Analysis of Variance; Animals; Cells, Cultured; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Radiation; Female; Fibroblasts; Lung; Micronuclei, Chromosome-Defective; NG-Nitroarginine Methyl Ester; Probability; Radiation Dosage; Radiation Pneumonitis; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sensitivity and Specificity; Superoxide Dismutase | 2003 |
Protection from noise-induced lipid peroxidation and hair cell loss in the cochlea.
Topics: Acetylcysteine; Acoustic Stimulation; Animals; Auditory Threshold; Cell Count; Cochlea; Dinoprost; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Evoked Potentials, Auditory, Brain Stem; F2-Isoprostanes; Free Radical Scavengers; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Noise; Piperidines; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2003 |
Adrenomedullin requires an intact nitric oxide system to function as an endogenous vasodilator in rat gestation.
Topics: Adrenomedullin; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fetal Growth Retardation; Fetal Weight; Infusions, Intravenous; Litter Size; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Systole; Vasodilator Agents | 2003 |
Systemic microvascular leak in an in vivo rat model of ventilator-induced lung injury.
Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Creatinine; Disease Models, Animal; Endothelial Growth Factors; Hemodynamics; Immunoblotting; Intercellular Signaling Peptides and Proteins; Kidney; Lung; Lymphokines; Male; Metabolic Clearance Rate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Respiratory Distress Syndrome; Sodium Chloride; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Inhibiting the NO pathway with intracoronary L-NAME infusion increases endothelial dysfunction and intimal hyperplasia after heart transplantation.
Topics: Animals; Coronary Artery Disease; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Female; Graft Rejection; Heart Transplantation; Hyperplasia; Infusions, Parenteral; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Severity of Illness Index; Signal Transduction; Swine; Time Factors; Tunica Intima | 2003 |
Intervention with nitric oxide synthase inhibitors for traumatic shock in rats.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Shock, Traumatic; Treatment Outcome | 2003 |
Chronic inhibition of nitric oxide synthase induces hypertension and cardiomyocyte mitochondrial and myocardial collagen remodelling in the absence of hypertrophy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Collagen; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Mitochondria, Heart; Models, Cardiovascular; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Predictive Value of Tests; Randomized Controlled Trials as Topic; Rats; Rats, Wistar; Severity of Illness Index; Time Factors; Treatment Outcome | 2003 |
Effect of a selective inducible nitric oxide synthase inhibitor on intraocular nitric oxide production in endotoxin-induced uveitis rabbits: in vivo intraocular microdialysis study.
Topics: Animals; Aqueous Humor; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Dioxide; Nitrogen Oxides; Rabbits; Salmonella typhimurium; Thiourea; Uveitis | 2003 |
[Mechanism of nitric oxide-dependent skin vasodilation during febrilysis].
Topics: Animals; Arginine; Body Temperature Regulation; Disease Models, Animal; Enzyme Inhibitors; Fever; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Skin; Vasodilation | 2003 |
Role of nitric oxide in posthypoxic contractile dysfunction of diabetic cardiomyopathy.
Topics: Animals; Cardiomyopathies; Coronary Circulation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Female; Glycated Hemoglobin; Heart Rate; Heart Ventricles; Male; Models, Cardiovascular; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxygen; Rats; Rats, Wistar; Severity of Illness Index; Streptozocin; Stroke Volume; Ventricular Function, Left; Ventricular Pressure | 2003 |
Enhanced umbilical blood flow during acute hypoxemia after chronic umbilical cord compression: a role for nitric oxide.
Topics: Acute Disease; Animals; Blood Flow Velocity; Blood Gas Analysis; Chronic Disease; Constriction, Pathologic; Disease Models, Animal; Enzyme Inhibitors; Fetal Diseases; Fetus; Hemodynamics; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Regional Blood Flow; Sheep; Umbilical Cord | 2003 |
Change in lipid profile and impairment of endothelium-dependent relaxation of blood vessels in rats after bile duct ligation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arteriosclerosis; Bile Ducts; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Endothelium, Vascular; Ligation; Lipids; Liver Cirrhosis, Experimental; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Organ Size; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasodilation | 2003 |
Diabetes differentially modulated receptor- and non-receptor-mediated relaxation in rat renal artery.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Body Weight; Calcimycin; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Renal Artery; Vasodilation; Vasodilator Agents | 2003 |
Type II nitric oxide synthase activity is cardio-protective in experimental sepsis.
Topics: Amidines; Animals; Benzylamines; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Heart; Heart Function Tests; Lipopolysaccharides; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Sepsis | 2003 |
Rescue of hypercholesterolemia-related impairment of angiogenesis by oral folate supplementation.
Topics: Administration, Oral; Animals; Cholesterol; Cholesterol, HDL; Cyclic GMP; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Folic Acid; Hindlimb; Homocysteine; Hypercholesterolemia; Ischemia; Male; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peripheral Vascular Diseases; Rats; Rats, Sprague-Dawley; Risk Factors; Severity of Illness Index | 2003 |
Erythrocyte ion transport and membrane lipid composition in young and adult rats with NO-deficient hypertension.
Topics: Animals; Biological Transport, Active; Disease Models, Animal; Erythrocyte Membrane; Erythrocytes; Hypertension; Ion Transport; Male; Membrane Lipids; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Potassium; Rats; Rats, Wistar; Sodium; Sodium-Potassium-Exchanging ATPase | 2003 |
[The role of nitric oxide in lung injury associated with acute necrotizing pancreatitis].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Female; Histocytochemistry; Lung; Lung Injury; Macrophages, Alveolar; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pancreatitis, Acute Necrotizing; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
SL65.0472 blocks 5-hydroxytryptamine-induced vasoconstriction in a dog hindlimb ischemia model.
Topics: Animals; Disease Models, Animal; Dogs; Hindlimb; Ischemia; Male; NG-Nitroarginine Methyl Ester; Piperazines; Quinolines; Regional Blood Flow; Serotonin; Serotonin Antagonists; Vasoconstriction | 2003 |
[The effects of L-arginine and NG-nitro-L-arginine methylester on lipopolysaccharide and lipoteichoic acid induced liver injury in the rat].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Liver; Liver Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Teichoic Acids | 2003 |
[The role of supplementation or inhibition of nitric oxide production in burn injury to reduce ischemic damage].
Topics: Animals; Arginine; Burns; Disease Models, Animal; Enzyme Inhibitors; Ischemia; Lipid Peroxidation; Lung; Lung Injury; Male; Malondialdehyde; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2003 |
Simvastatin ameliorates injury in an experimental model of lung ischemia-reperfusion.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cell Count; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Ischemia; Lung; Lung Diseases; Male; Models, Cardiovascular; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Long-Evans; Reperfusion Injury; Simvastatin; Statistics as Topic; Time Factors; Transcription Factors; Treatment Outcome | 2003 |
Putative anxiety-linked effects of the nitric oxide synthase inhibitor L-NAME in three murine exploratory behavior models.
Topics: Animals; Anxiety; Darkness; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Lighting; Male; Maze Learning; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase | 2003 |
Effects of in vivo treatment with interleukins 1beta and 6 on rat mesenteric vascular bed reactivity.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Endothelin-1; Fever; Guanethidine; Inflammation; Interleukin-1; Interleukin-6; Intestinal Mucosa; Isomerism; Isoproterenol; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Sumatriptan; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation | 2003 |
Effect of poly(ADP-ribose) polymerase inhibition on outer medullary hypoxic damage.
Topics: Acute Kidney Injury; Animals; Benzamides; Contrast Media; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Indomethacin; Kidney Function Tests; Kidney Medulla; Kidney Tubules; Male; Necrosis; NG-Nitroarginine Methyl Ester; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2003 |
The neuroprotective effect of a novel calmodulin antagonist, 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate, in transient forebrain ischemia.
Topics: Animals; Blotting, Western; Brain Ischemia; Calmodulin; Carotid Artery, Internal, Dissection; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme Inhibitors; Gerbillinae; Hippocampus; Immunohistochemistry; Indazoles; Ischemic Attack, Transient; Male; Microdialysis; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Reperfusion; Time Factors; Tyrosine | 2003 |
PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes.
Topics: Acetylcholine; Adenosine; Animals; Arterioles; Biological Availability; Coronary Vessels; Diabetes Mellitus, Type 2; Disease Models, Animal; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Vasodilation | 2004 |
Cedrelopsis grevei induced hypotension and improved endothelial vasodilatation through an increase of Cu/Zn SOD protein expression.
Topics: Acetylcholine; Administration, Oral; Animals; Antihypertensive Agents; Aorta; Arterioles; Disease Models, Animal; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Vasodilation | 2004 |
Secretory dysfunction of vascular endothelium limits the effect of angiotensin converting enzyme inhibitor quinapril on aggregation of erythrocytes in experimental hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Blood Pressure; Bradykinin; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Epoprostenol; Erythrocyte Aggregation; Hypertension; Indomethacin; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Quinapril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrahydroisoquinolines | 2003 |
Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model.
Topics: Animals; Blood Pressure; Cattle; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Hindlimb; Ischemia; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Plasmids; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2003 |
Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury.
Topics: Aldosterone; Angiotensin II; Animals; Cardiovascular Diseases; Coronary Artery Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Myocardium; NG-Nitroarginine Methyl Ester; Plasminogen Activator Inhibitor 1; Proteinuria; Sodium, Dietary; Spironolactone | 2003 |
Novel anti-inflammatory actions of amlodipine in a rat model of arteriosclerosis induced by long-term inhibition of nitric oxide synthesis.
Topics: Amlodipine; Animals; Anti-Inflammatory Agents; Arteriosclerosis; Base Sequence; Blood Pressure; Disease Models, Animal; DNA Primers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrogen Oxides; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Rats, Inbred WKY; Superoxides; Vasodilator Agents | 2004 |
Involvement of nitric oxide and prostaglandin pathways in the cardioprotective actions of bradykinin in rats with experimental myocardial infarction.
Topics: Animals; Aspirin; Bradykinin; Disease Models, Animal; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Injections, Intravenous; Lisinopril; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Peptides; Rats; Rats, Sprague-Dawley; Staining and Labeling; Tetrazolium Salts | 2004 |
Gender-specific genetic determinants of blood pressure and organ weight: pharmacogenetic approach.
Topics: Animals; Blood Pressure; Body Weight; Chromosomes, Mammalian; Crosses, Genetic; Disease Models, Animal; Female; Genotype; Heart; Hypertension; Kidney; Lod Score; Losartan; Male; Microvascular Angina; Multifactorial Inheritance; NG-Nitroarginine Methyl Ester; Organ Size; Pentolinium Tartrate; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Quantitative Trait Loci; Rats; Rats, Inbred Lew; Rats, Wistar; Sex Factors | 2003 |
Multiple cedar pollen challenge diminishes involvement of histamine in allergic conjunctivitis of Guinea pigs.
Topics: Administration, Oral; Administration, Topical; Albumins; Allergens; Animals; Conjunctivitis, Allergic; Cryptomeria; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Tolerance; Eye; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Injections, Intraperitoneal; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plant Extracts; Pollen; Pruritus; Pyrilamine; Time Factors | 2003 |
Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycosaminoglycans; Guanidines; Injections, Intra-Articular; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Synovial Fluid; Synovial Membrane; Synovitis; Tyrosine; Uric Acid; Zymosan | 2004 |
Effect of nitric oxide synthase inhibition and saline administration on blood pressure and renal sodium handling during experimental sepsis in rats.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Pressure Determination; Disease Models, Animal; Glomerular Filtration Rate; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Sepsis; Sodium Chloride | 2003 |
Effects of intrarectal and intraperitoneal N(G)-nitro-L-arginine methyl ester treatment in 2,4,6-trinitrobenzenesulfonic acid induced colitis in rats.
Topics: Acute Disease; Administration, Rectal; Animals; Colitis; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Ethanol; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitrites; Peroxidase; Rats; Rats, Sprague-Dawley; Rectum; Treatment Outcome; Trinitrobenzenesulfonic Acid | 2003 |
[Influence of inhibitors of nitric oxide synthase and L-arginine on the survival rate in a rat model of traumatic shock].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Traumatic; Survival Rate; Treatment Outcome | 2004 |
Topical application of a nitric oxide synthase inhibitor reduces intraocular pressure in rabbits with experimental glaucoma.
Topics: Administration, Topical; Animals; Anterior Chamber; Area Under Curve; Chemistry, Pharmaceutical; Chymotrypsin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glaucoma; Injections; Intraocular Pressure; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ophthalmic Solutions; Rabbits; Solvents | 2003 |
Functional study of the [Ca2+]i signaling pathway in aortas of L-NAME-hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Administration, Oral; Animals; Aorta, Thoracic; Caffeine; Calcium; Calcium Signaling; Disease Models, Animal; Drug Synergism; Endothelium, Vascular; Hypertension; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Phenylephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins; Protein Kinase C; Rats; Rats, Wistar; Time Factors; Tunica Intima; Vasoconstriction | 2004 |
Effects of L-arginine and NG-nitro L-arginine methyl ester on lipid peroxide, superoxide dismutase and nitrate levels after experimental sciatic nerve ischemia-reperfusion in rats.
Topics: Animals; Arginine; Disease Models, Animal; Female; Histological Techniques; Laparotomy; Lipid Peroxides; Male; Microscopy, Electron; Myelin Sheath; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Sciatic Nerve; Statistics, Nonparametric; Superoxide Dismutase; Time Factors | 2004 |
Interaction between endogenous nitric oxide and carbon monoxide in the pathogenesis of recurrent febrile seizures.
Topics: Animals; Brain; Carbon Monoxide; Citrates; Cyclic GMP; Disease Models, Animal; Electrophoresis, Agar Gel; Enzyme Inhibitors; Ethidium; Heme Oxygenase (Decyclizing); Hippocampus; Immunohistochemistry; Intercalating Agents; Lead; Male; Microscopy, Electron; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organometallic Compounds; Oxidoreductases; Protoporphyrins; Rats; Rats, Sprague-Dawley; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; Seizures, Febrile | 2004 |
Anti-lipid deposition effect of HMG-CoA reductase inhibitor, pitavastatin, in a rat model of hypertension and hypercholesterolemia.
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Quinolines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 2004 |
The herbal medicine Toki-shakuyaku-san improves the hypertension and intrauterine growth retardation in preeclampsia rats induced by Nomega-nitro-L-arginine methyl ester.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetal Growth Retardation; Fetus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phytotherapy; Plants, Medicinal; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Leukocyte behavior in angiogenic vessels is affected by tumor-derived nitric oxide.
Topics: Animals; Cell Adhesion; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Fluorescein; Fluorescent Dyes; Hemodynamics; Leukocytes; Male; Mesentery; Microcirculation; Microscopy, Confocal; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peritoneal Neoplasms; Rats; Rats, Inbred F344 | 2003 |
Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition.
Topics: Acetylcholine; Animals; Arginine; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Female; Fetus; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Vasodilation | 2004 |
Effects of the angiotensin-converting enzyme inhibitor perindopril on endothelial injury and hemostasis in rabbit endotoxic shock.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Gas Analysis; Disease Models, Animal; Endothelium, Vascular; Hemostasis; Immunohistochemistry; NG-Nitroarginine Methyl Ester; Perindopril; Rabbits; Regression Analysis; Shock, Septic; Statistics, Nonparametric | 2004 |
Vasoactive systems in L-NAME hypertension: the role of inducible nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Heart Ventricles; Hypertension; Injections, Intravenous; Male; Models, Cardiovascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Renin-Angiotensin System; Time Factors; Vasoconstriction; Vasodilator Agents | 2004 |
Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Blood Pressure; Colforsin; Disease Models, Animal; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Losartan; Male; Models, Cardiovascular; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; RNA, Messenger; Sodium Fluoride; Statistics as Topic | 2004 |
Nitric oxide synthase inhibition accelerates the pressor response to low-dose angiotensin II, exacerbates target organ damage, and induces renin escape.
Topics: Angiotensin II; Animals; Biomarkers; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrosis; Infusions, Intravenous; Kidney; Models, Cardiovascular; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Sprague-Dawley; Renin; Time Factors; Troponin T; Vasoconstrictor Agents | 2004 |
Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats.
Topics: Animals; Biomarkers; Catalysis; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Enzyme Inhibitors; Fluorescent Dyes; Guanidines; I-kappa B Proteins; Leukocytes; Metalloporphyrins; Models, Cardiovascular; Myocarditis; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine; Xanthenes | 2004 |
Aortic wall remodeling in rats with nitric oxide deficiency treated by enalapril or verapamil.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Therapy, Combination; Enalapril; Heart Ventricles; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Verapamil | 2004 |
The renin-angiotensin system: a 21st century perspective.
Topics: Angiotensin II; Animals; Diabetes Mellitus; Disease Models, Animal; Humans; NG-Nitroarginine Methyl Ester; Reactive Oxygen Species; Renin; Renin-Angiotensin System | 2004 |
Vasopeptidase inhibition improves insulin sensitivity and endothelial function in the JCR:LA-cp rat.
Topics: Acetylcholine; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Aorta, Thoracic; Blood Glucose; Body Weight; Bradykinin; Diet; Disease Models, Animal; Eating; Endothelium, Vascular; Fasting; Heart; Heart Rate; Heterocyclic Compounds, 3-Ring; Insulin; Insulin Resistance; Male; Muscle, Smooth, Vascular; Neprilysin; NG-Nitroarginine Methyl Ester; Nitroprusside; Obesity; Organ Size; Phenylephrine; Ramipril; Rats; Vasoconstriction; Vasodilation | 2004 |
Effects of aminoguanidine and L-arginine methyl ester resuscitation following induction of fluid-percussion injury and severe controlled hemorrhagic shock in the rat brain.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Rate | 2004 |
Influence of temporomandibular joint pain on sleep patterns: role of nitric oxide.
Topics: Animals; Arginine; Arthritis, Experimental; Disease Models, Animal; Enzyme Inhibitors; Facial Pain; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Wistar; Sleep Stages; Sleep Wake Disorders; Sleep, REM; Temporomandibular Joint Disorders; Time Factors | 2004 |
Preemptive effects of intrathecal cyclooxygenase inhibitor or nitric oxide synthase inhibitor on thermal hypersensitivity following peripheral nerve injury.
Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrobenzenes; Pain; Pain Threshold; Piroxicam; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sulfonamides | 2004 |
Modulation of germ cell apoptosis with a nitric oxide synthase inhibitor in a murine model of congenital cryptorchidism.
Topics: Animals; Apoptosis; Cryptorchidism; Disease Models, Animal; Enzyme Inhibitors; Germ Cells; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase | 2004 |
Nitric oxide modulation of early angiogenesis.
Topics: Analysis of Variance; Animals; Animals, Newborn; Arginine; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Probability; Reference Values; Sensitivity and Specificity; Wound Healing | 2004 |
Peripheral involvement of the nitric oxide-cGMP pathway in the indomethacin-induced antinociception in rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Gout; Indomethacin; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Pain; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar; Signal Transduction; Uric Acid | 2004 |
Progestins used in hormonal replacement therapy display different effects in coronary arteries from New Zealand white rabbits.
Topics: Acetylcholine; Animals; Arteries; Calcium; Coronary Vessels; Disease Models, Animal; Endothelin-1; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Medroxyprogesterone Acetate; Menopause; NG-Nitroarginine Methyl Ester; Nitroprusside; Norethindrone; Norethindrone Acetate; Ovariectomy; Potassium; Progestins; Rabbits; Vasoconstriction; Vasodilation | 2004 |
Decreased aortic smooth muscle contraction in a rat model of multibacterial sepsis.
Topics: Animals; Aorta; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Sepsis; Soluble Guanylyl Cyclase | 2004 |
The role of 5-hydroxytryptamine in the control of pulmonary vascular tone in a rabbit model of pulmonary hypertension secondary to left ventricular dysfunction.
Topics: Animals; Aorta; Blood Pressure; Cardiac Output; Disease Models, Animal; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Ketanserin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Organ Size; Pulmonary Artery; Rabbits; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Antagonists; Stroke Volume; Ventricular Dysfunction, Left | 2005 |
The role of nitric oxide in iron-induced rat renal injury.
Topics: Animals; Arginine; Deferoxamine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Iron; Iron Chelating Agents; Iron Overload; Kidney; Kidney Diseases; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E | 2004 |
l-Arginine attenuates acute pulmonary embolism-induced oxidative stress and pulmonary hypertension.
Topics: Acute Disease; Animals; Arginine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pulmonary Artery; Pulmonary Embolism; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2005 |
Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Irritable Bowel Syndrome; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1 | 2005 |
Inhibition of glucocorticoid receptor binding by nitric oxide in endotoxemic rats.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endotoxemia; Escherichia coli Infections; Female; Lipopolysaccharides; Liver; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Receptors, Glucocorticoid; S-Nitroso-N-Acetylpenicillamine; Shock, Septic; Spleen; Tyrosine Transaminase | 2004 |
Potential effects of L-NAME on alcohol-induced oxidative stress.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Lipid Peroxidation; Liver; Liver Diseases, Alcoholic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar | 2005 |
Substitution of chromosome 1 ameliorates L-NAME hypertension and renal disease in the fawn-hooded hypertensive rat.
Topics: Animals; Blood Pressure; Chromosome Mapping; Chromosomes, Mammalian; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Female; Heart Rate; Hypertension, Renal; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred BN; Rats, Mutant Strains | 2005 |
Effect of quercetine and glutathione on the level of superoxide dismutase, catalase, malonyldialdehyde, blood pressure and neonatal outcome in a rat model of pre-eclampsia induced by NG-nitro-L-arginine-methyl ester.
Topics: Animals; Antioxidants; Birth Weight; Blood Pressure; Catalase; Disease Models, Animal; Enzyme Inhibitors; Female; Gestational Age; Glutathione; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Proteinuria; Quercetin; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2005 |
Mechanisms underlying quercetin-induced vasorelaxation in aorta of subchronic diabetic rats: an in vitro study.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Potassium Chloride; Quercetin; Rats; Streptozocin; Vasoconstriction; Vasodilation | 2004 |
Nitric oxide synthases inhibition results in renal failure improvement in cirrhotic rats.
Topics: Animals; Aspartate Aminotransferases; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Kidney; Liver; Liver Cirrhosis, Experimental; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Renal Insufficiency; RNA, Messenger; Sodium | 2005 |
Anticonvulsant effect of Hypericum perforatum: role of nitric oxide.
Topics: Animals; Anticonvulsants; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Ethanol; Hypericum; Injections, Intraperitoneal; Lethal Dose 50; Medicine, Traditional; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Plant Components, Aerial; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Seizures; Water | 2005 |
Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.
Topics: Animals; Aorta, Thoracic; Biopterins; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Isoprostanes; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Oxidation-Reduction; Protein Subunits; Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; Superoxide Dismutase; Superoxides; Tyrosine; Vasodilation; Vasodilator Agents | 2005 |
The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascites.
Topics: Analysis of Variance; Animals; Ascites; Disease Models, Animal; Hemodynamics; Infusions, Intravenous; Liver Cirrhosis, Experimental; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Probability; Random Allocation; Rats; Rats, Wistar; Sensitivity and Specificity; Vascular Resistance; Vasodilation | 2005 |
The role of nitric oxide in the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats.
Topics: Animals; Brain; Cortical Spreading Depression; Cyclooxygenase 2; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Ischemic Preconditioning; Male; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2005 |
Combined treatment of ascorbic acid or alpha-tocopherol with dopamine receptor antagonist or nitric oxide synthase inhibitor potentiates cataleptic effect in mice.
Topics: alpha-Tocopherol; Animals; Ascorbic Acid; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Enzyme Inhibitors; Haloperidol; Indazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Time Factors; Vitamins | 2005 |
Nitrogen oxide blockade does not aggravate the endothelin-1-induced myocardial ischemia and release of purine metabolites from the dog heart.
Topics: Adaptation, Physiological; Adenosine; Animals; Disease Models, Animal; Dogs; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypoxanthine; Inosine; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pericardium; Purines | 2004 |
Nitric oxide protects against ischemic acute renal failure through the suppression of renal endothelin-1 overproduction.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Injections, Intravenous; Kidney; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitro Compounds; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors | 2004 |
Involvement of nitric oxide in the suppressive effect of 17beta-estradiol on endothelin-1 overproduction in ischemic acute renal failure.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Estradiol; Kidney; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors | 2004 |
Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats.
Topics: Animals; Antioxidants; Brain; Catalase; Cerebral Cortex; Chromans; Disease Models, Animal; Enzyme Inhibitors; Fluoresceins; Free Radicals; Glutathione; Glutathione Peroxidase; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Mitochondria; Neurons; NG-Nitroarginine Methyl Ester; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Valine | 2005 |
Coronary effects of endothelin-1 and vasopressin during acute hypotension in anesthetized goats.
Topics: Acute Disease; Anesthesia; Animals; Blood Pressure; Coronary Circulation; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelin-1; Female; Goats; Hypotension; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Vasoconstriction; Vasopressins | 2005 |
Chronic administration of aminoguanidine reduces vascular nitric oxide production and attenuates liver damage in bile duct-ligated rats.
Topics: Animals; Aorta; Bile Ducts; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Ligation; Liver Cirrhosis; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley | 2005 |
Spontaneous stroke in a genetic model of hypertension in mice.
Topics: Angiotensinogen; Animal Feed; Animals; Blood Pressure; Brain; Circadian Rhythm; Disease Models, Animal; Female; Humans; Hypertension; Intracranial Hemorrhages; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Renin; Salts; Stroke | 2005 |
Antioxidant enzymes and effects of tempol on the development of hypertension induced by nitric oxide inhibition.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Biomarkers; Blood Pressure; Catalase; Cyclic N-Oxides; Deoxyguanosine; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxidase; Glutathione Reductase; Heart Rate; Heart Ventricles; Hypertension; Kidney Cortex; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar; Spectrophotometry; Spin Labels; Superoxide Dismutase | 2005 |
Effects of acute and chronic nitric oxide inhibition in an experimental model of chronic pulmonary allergic inflammation in guinea pigs.
Topics: Animals; Asthma; Chronic Disease; Collagen; Disease Models, Animal; Enzyme Inhibitors; Guinea Pigs; Leukocytes, Mononuclear; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovalbumin; Pneumonia; Pulmonary Edema | 2005 |
Alterations of alpha-adrenergic modulations of coronary microvascular tone in dogs with heart failure.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Cineangiography; Coronary Angiography; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Enzyme Inhibitors; Female; Heart Failure; Injections, Intra-Arterial; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Propranolol; Quinazolines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vascular Resistance; Vasodilation; Yohimbine | 2005 |
Up-regulation of nNOS and associated increase in nitrergic vasodilation in superior mesenteric arteries in pre-hepatic portal hypertension.
Topics: Animals; Blotting, Western; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Portal; Immunohistochemistry; Male; Mesenteric Artery, Superior; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Up-Regulation; Vasodilation | 2005 |
The effect of herbal medicine Toki-shakuyaku-san on blood pressure in an Nomega-nitro-L-arginine methyl ester-induced pre-eclampsia rat model during pregnancy and the postpartum period.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Drugs, Chinese Herbal; Estradiol; Female; Male; Mifepristone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pre-Eclampsia; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley | 2005 |
Blood pressure variability, cardiac baroreflex sensitivity and organ damage in experimentally hypertensive rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Blood Pressure Determination; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Hypertension; Hypertension, Renovascular; Interleukin-1; Kidney Glomerulus; Male; Myocardium; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Morphologic changes of the uteroplacental unit in preeclampsia-like syndrome in rats.
Topics: Animals; Body Weight; Disease Models, Animal; Female; Hemodynamics; Litter Size; NG-Nitroarginine Methyl Ester; Nitric Oxide; Placenta; Placental Circulation; Pre-Eclampsia; Pregnancy; Pregnancy, Animal; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Syndrome; Uterus | 2005 |
Pre-ischemic administration of nitric oxide synthase inhibitors reduced germ cell apoptosis after spermatic vessel ligation in the rat testis.
Topics: Animals; Apoptosis; Cryptorchidism; Disease Models, Animal; Enzyme Inhibitors; In Situ Nick-End Labeling; Ischemia; Ligation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Wistar; Spermatic Cord; Spermatozoa; Testis | 2005 |
Ultrastructure and histochemistry of rat myocardial capillary endothelial cells in response to diabetes and hypertension.
Topics: Animals; Capillaries; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Endothelial Cells; Heart Failure; Hypertension; Immunohistochemistry; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Streptozocin | 2005 |
Physical training increases renal injury in rats with chronic NOS inhibition.
Topics: Adaptation, Physiological; Animals; Body Weight; Disease Models, Animal; Hemodynamics; Hypertension; Hypertension, Renal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Physical Conditioning, Animal; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity | 2005 |
Effects of long term NOS inhibition on disease and the immune system in MOG induced EAE.
Topics: Animals; Antibodies; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Spleen; T-Lymphocytes | 2005 |
[Inhibition of nitric oxide synthesis during bacterial shock does not prevent development of resistant hypotension and death in rats].
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypotension; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Shock, Septic | 2005 |
Statin monotherapy attenuates renal injury in a salt-sensitive hypertension model of renal disease.
Topics: Albuminuria; Animals; Cell Division; Chemokine CCL2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; Enzyme Inhibitors; Extracellular Matrix; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Renal; Lymphocytes; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; RNA, Messenger; Simvastatin; Sodium Chloride; Transforming Growth Factor beta | 2005 |
Effect of nitric oxide synthase inhibition on changes induced by estradiol in bladders from ovariectomized rabbits.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Cystoscopy; Disease Models, Animal; Estradiol; Female; Immunohistochemistry; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ovariectomy; Probability; Rabbits; Random Allocation; Reference Values; Regional Blood Flow; Risk Factors; Sensitivity and Specificity; Urinary Bladder; Urinary Bladder Diseases; Vascular Resistance | 2005 |
Myocardial infarction increases reactivity to phenylephrine in isolated aortic rings of ovariectomized rats.
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Female; In Vitro Techniques; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovariectomy; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents | 2006 |
L-Arginine prevents air embolism-induced acute lung injury in rats.
Topics: Acute Disease; Animals; Arginine; Bronchoalveolar Lavage; Capillary Permeability; Disease Models, Animal; Embolism, Air; Hypertension, Pulmonary; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Organ Size; Proteins; Pulmonary Edema; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Augmentation of pulse wave velocity precedes vascular structural changes of the aorta in rats treated with N(omega)-nitro-L-arginine methyl ester.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Blood Flow Velocity; Disease Models, Animal; Early Diagnosis; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulsatile Flow; Rats; Rats, Inbred WKY | 2005 |
Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis.
Topics: Animals; Budd-Chiari Syndrome; Disease Models, Animal; Hepatic Veno-Occlusive Disease; Indoleacetic Acids; Indoles; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plasminogen Activator Inhibitor 1 | 2006 |
Contribution of cytochrome P450 metabolites of arachidonic acid to hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME.
Topics: Animals; Arachidonic Acid; Blood Pressure; Blood Vessels; Collagen Type III; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Isoproterenol; Kidney; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation; Triazoles; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Angiotensin II sensitivity of afferent glomerular arterioles in endothelin-1 transgenic mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gene Expression; In Vitro Techniques; Kidney Glomerulus; Male; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polymerase Chain Reaction; Receptors, Angiotensin; Renal Artery; Renin; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Ultrastructure of immediate microvascular lung injury induced by bacterial endotoxin in the isolated, no-deficient lung perfused with full blood.
Topics: Animals; Bacterial Infections; Blood Pressure; Blood-Air Barrier; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Lipopolysaccharides; Lung; Lysine; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Perfusion; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Wistar; Tidal Volume; Vasoconstriction; Venous Pressure | 2005 |
Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse.
Topics: Animals; Antioxidants; Central Nervous System; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Hot Temperature; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Isoxazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain; Pain Threshold; Sciatic Nerve; Time Factors; Touch; Zonisamide | 2005 |
Contribution of endogenous opioids and nitric oxide to papillary muscle contractile impairment in cholestatic rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Bile Ducts; Cardiomyopathies; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoproterenol; Ligation; Male; Myocardial Contraction; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Opioid Peptides; Papillary Muscles; Phenylephrine; Rats; Rats, Sprague-Dawley | 2005 |
Different effects of dexamethasone and the nitric oxide synthase inhibitor L-NAME on caerulein-induced rat acute pancreatitis, depending on the severity.
Topics: Acute Disease; Administration, Oral; Amylases; Animals; Anti-Inflammatory Agents; Ceruletide; Dexamethasone; Disease Models, Animal; Enzyme Inhibitors; Injections, Subcutaneous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Size; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Wistar; Severity of Illness Index | 2005 |
Enhanced acetylcholine-induced dilation in afferent arterioles in simvastatin-fed rats.
Topics: Acetylcholine; Animals; Arterioles; Diet; Disease Models, Animal; Enzyme Inhibitors; Hydronephrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Microscopy, Video; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Simvastatin; Vasodilation; Vasodilator Agents | 2006 |
Possible role of nitric oxide in the protective effect of resveratrol in 5/6th nephrectomized rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Pressure; Body Weight; Disease Models, Animal; Eating; Enzyme Inhibitors; Kidney Function Tests; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Proteinuria; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Resveratrol; Stilbenes; Survival Rate | 2006 |
Role of nitric oxide in resveratrol-induced renal protective effects of ischemic preconditioning.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Biomarkers; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Ischemic Preconditioning; Kidney; Kidney Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2005 |
Renal effects of human urotensin-II in rats with experimental congestive heart failure.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Glomerular Filtration Rate; Heart Failure; Hemodynamics; Humans; Indomethacin; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Probability; Rats; Rats, Wistar; Reference Values; Renal Circulation; Risk Factors; Sensitivity and Specificity; Up-Regulation; Urodynamics; Urotensins | 2006 |
Effect of nitric oxide and peroxynitrite on mucociliary transport function of experimental otitis media.
Topics: Animals; Disease Models, Animal; Free Radical Scavengers; Guinea Pigs; Lipopolysaccharides; Mucociliary Clearance; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Otitis Media with Effusion; Peroxynitrous Acid; Pseudomonas aeruginosa; Uric Acid | 2006 |
Renal thrombotic microangiopathy in a genetic model of hypertension in mice.
Topics: Angiotensins; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertension; Kidney; Kidney Glomerulus; Mice; Mice, Transgenic; Microcirculation; NG-Nitroarginine Methyl Ester; Renal Circulation; Renin; Sodium, Dietary | 2006 |
Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Atenolol; Biomarkers; Blood Pressure; Blotting, Northern; Blotting, Western; Carbazoles; Carvedilol; Cells, Cultured; Connexin 43; Connexins; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Follow-Up Studies; Gap Junction alpha-4 Protein; Humans; Hypertension; Immunohistochemistry; In Vitro Techniques; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Propanolamines; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome; Umbilical Veins | 2006 |
Long-term effect of pentoxifylline and NG-nitro-L-arginine methyl ester on testicular function in spermatic artery ligation.
Topics: Animals; Biopsy, Needle; Disease Models, Animal; Immunohistochemistry; Ligation; Male; NG-Nitroarginine Methyl Ester; Orchiectomy; Pentoxifylline; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Risk Factors; Sensitivity and Specificity; Spermatic Cord; Spermatogenesis; Statistics, Nonparametric; Testis | 2006 |
Sulfisoxazole, an endothelin receptor antagonist, protects retinal neurones from insults of ischemia/reperfusion or lipopolysaccharide.
Topics: Animals; Animals, Newborn; Anti-Infective Agents; Cell Death; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Glaucoma; Lipopolysaccharides; Nerve Degeneration; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, Endothelin; Reperfusion Injury; Retinal Degeneration; Sulfisoxazole; Thy-1 Antigens | 2006 |
Nitric oxide mediates the blood-pressure lowering effect of garlic in the rat two-kidney, one-clip model of hypertension.
Topics: Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plant Extracts; Rats; Rats, Sprague-Dawley; Reference Values | 2006 |
Promotion of oxidative stress by L-tryptophan in cerebral cortex of rats.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Antioxidants; Catalase; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Free Radicals; Glutathione; Lipid Peroxidation; Luminescence; Male; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tryptophan | 2006 |
Endothelium-dependent inhibition of the contractile response is decreased in aorta from aged and spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta; Disease Models, Animal; Endothelium; Hypertension; Indomethacin; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Serotonin | 2006 |
Role of reactive nitrogen species in development of hepatic injury in a C57bl/6 mouse model of human granulocytic anaplasmosis.
Topics: Anaplasma phagocytophilum; Animals; Disease Models, Animal; Ehrlichiosis; Enzyme Inhibitors; Hepatitis; Humans; Liver; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Reactive Nitrogen Species | 2006 |
Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection.
Topics: Animals; Arginine; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Interleukin-1; Interleukin-6; Lung; Lung Diseases; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pseudomonas Infections; Rats; Rats, Inbred WKY; Tyrosine; Vascular Endothelial Growth Factor A | 2006 |
Erythropoietin reduces perihematomal inflammation and cell death with eNOS and STAT3 activations in experimental intracerebral hemorrhage.
Topics: Animals; Apoptosis; Biomarkers; Body Water; Brain; Brain Edema; Cell Death; Cerebral Hemorrhage; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Enzyme Activation; Enzyme Inhibitors; Erythropoietin; Male; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Recovery of Function; Signal Transduction; STAT3 Transcription Factor; Treatment Outcome | 2006 |
Cyclooxygenase-2 mediates the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats.
Topics: Animals; Cerebral Cortex; Cerebral Infarction; Cortical Spreading Depression; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytoprotection; Disease Models, Animal; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Ischemic Preconditioning; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Chloride; Prostaglandin D2; Rats; Rats, Wistar; Up-Regulation | 2006 |
Colonic electrical stimulation regulates colonic transit via the nitrergic pathway in rats.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Gastrointestinal Transit; Irritable Bowel Syndrome; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity | 2006 |
Influence of nitric oxide on morphine-induced amnesia and interactions with dopaminergic receptor agents.
Topics: Amnesia; Analysis of Variance; Animals; Arginine; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Reaction Time | 2006 |
L-NAME prevents anxiety-like and depression-like behavior in rats exposed to restraint stress.
Topics: Acute Disease; Animals; Anxiety; Arginine; Chronic Disease; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological | 2006 |
Magnesium sulfate effectively reduces blood pressure in an animal model of preeclampsia.
Topics: Animals; Animals, Newborn; Anticonvulsants; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Female; Fetal Growth Retardation; Forelimb; Heart Rate; Magnesium Sulfate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2006 |
Evidence for a role of inducible nitric oxide synthase in gastric relaxation of mdx mice.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Imines; Male; Mice; Mice, Inbred mdx; Muscle Relaxation; Muscle, Smooth; Muscular Dystrophy, Duchenne; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Receptors, Vasoactive Intestinal Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Vasoactive Intestinal Peptide | 2006 |
Endothelin and nitric oxide mediate adaptation of the cortical collecting duct to metabolic acidosis.
Topics: Acclimatization; Acidosis; Animals; Bicarbonates; Biological Transport; Cell Polarity; Chlorides; Disease Models, Animal; Endothelins; Hydrogen-Ion Concentration; Kidney Tubules, Collecting; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Piperidines; Rabbits | 2006 |
MgSO4 prevents left ventricular dysfunction in an animal model of preeclampsia.
Topics: Animals; Cardiac Output; Disease Models, Animal; Enzyme Inhibitors; Female; Heart; Hypertension; Magnesium Sulfate; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left | 2006 |
Role of T lymphocytes in hypertension-induced cardiac extracellular matrix remodeling.
Topics: Amino Acid Oxidoreductases; Animals; Collagen; Disease Models, Animal; Extracellular Matrix; Female; Gene Expression; Hypertension; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; NG-Nitroarginine Methyl Ester; Species Specificity; T-Lymphocytes; Ventricular Function, Left; Ventricular Remodeling | 2006 |
Microvascular versus macrovascular dysfunction in type 2 diabetes: differences in contractile responses to endothelin-1.
Topics: Acetylcholine; Animals; Basilar Artery; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Isometric Contraction; Male; Mesenteric Arteries; Muscle Contraction; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Strains; Rats, Wistar; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Melatonin attenuates renal ischemia-reperfusion injury in nitric oxide synthase inhibited rats.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Kidney; Male; Malondialdehyde; Melatonin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion Injury | 2006 |
A nitric oxide synthase inhibitor (L-NAME) attenuates abstinence-induced withdrawal from both cocaine and a cannabinoid agonist (WIN 55212-2) in Planaria.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Benzoxazines; Cannabinoids; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Morpholines; Motor Activity; Naphthalenes; NG-Nitroarginine Methyl Ester; Planarians; Substance Withdrawal Syndrome; Time Factors | 2006 |
The effect of L-arginine methyl ester on indices of free radical involvement in a rat model of experimental nephrocalcinosis.
Topics: Animals; Arginine; Blood Urea Nitrogen; Calcium Oxalate; Catalase; Creatinine; Crystallization; Disease Models, Animal; Enzyme Inhibitors; Free Radicals; Glutathione; Magnesium; Male; Nephrocalcinosis; NG-Nitroarginine Methyl Ester; Oxidative Stress; Potassium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Superoxide Dismutase; Uric Acid | 2006 |
Detrimental effects of nitric oxide inhibition on hepatic encephalopathy in rats with thioacetamide-induced fulminant hepatic failure: role of nitric oxide synthase isoforms.
Topics: Animals; Canavanine; Disease Models, Animal; Enzyme Inhibitors; Hepatic Encephalopathy; Liver Failure, Acute; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Thioacetamide; Treatment Outcome | 2006 |
Alpha1D-adrenoceptor-induced relaxation on rat carotid artery is impaired during the endothelial dysfunction evoked in the early stages of hyperhomocysteinemia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hyperhomocysteinemia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Superoxide Dismutase; Superoxides; Vasoconstriction; Vasodilation | 2006 |
Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart.
Topics: 6-Aminonicotinamide; Animals; Blood Pressure; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Heart Failure; Humans; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Superoxides; Teratogens; Time Factors | 2006 |
Sildenafil induces hyperalgesia via activation of the NO-cGMP pathway in the rat neuropathic pain model.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Chronic Disease; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Threshold; Piperazines; Purines; Rats; Rats, Wistar; Sciatic Neuropathy; Signal Transduction; Sildenafil Citrate; Sulfones | 2006 |
Pathogenic role of endothelial nitric oxide synthase (eNOS/NOS-III) in cerulein-induced rat acute pancreatitis.
Topics: Animals; Biomarkers; Blotting, Western; Capillary Permeability; Ceruletide; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Pancreatitis, Acute Necrotizing; Peroxidase; Rats; Rats, Wistar; Severity of Illness Index | 2006 |
Increased prostanoid dependency of arterial relaxation in Chlamydia pneumoniae-infected mice.
Topics: Animals; Aorta, Thoracic; Chlamydophila Infections; Chlamydophila pneumoniae; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Enzyme Inhibitors; Female; Methacholine Chloride; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prostaglandins; Vasoconstrictor Agents; Vasodilation | 2006 |
Whole-body periodic acceleration modifies experimental asthma in sheep.
Topics: Acceleration; Animals; Antigens, Helminth; Ascaris suum; Asthma; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Sheep; Stress, Mechanical | 2006 |
Chronic nitric oxide synthase inhibition in pregnant rats does not result in placental oxidative stress.
Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Liver; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar | 2006 |
Nitric oxide synthesis inhibition alters rat cutaneous wound healing.
Topics: Administration, Oral; Animals; Cell Count; Collagen; Disease Models, Animal; Enzyme Inhibitors; Male; Mast Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Skin; Water Supply; Wound Healing | 2006 |
Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Cerebral Infarction; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Activation; Enzyme Inhibitors; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reperfusion Injury; Rosuvastatin Calcium; Sulfonamides; Tetrazoles; Treatment Outcome | 2006 |
Altered tachykinergic influence on gastric mechanical activity in mdx mice.
Topics: Animals; Benzamides; Disease Models, Animal; Enzyme Inhibitors; Gastrointestinal Motility; Immunohistochemistry; Male; Manometry; Mice; Mice, Inbred mdx; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Muscular Dystrophy, Duchenne; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Organ Culture Techniques; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Stomach; Tachykinins | 2006 |
Role of the L-citrulline/L-arginine cycle in iNANC nerve-mediated nitric oxide production and airway smooth muscle relaxation in allergic asthma.
Topics: Allergens; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Asthma; Citrulline; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; N-Methylaspartate; Neural Inhibition; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Ovalbumin; Specific Pathogen-Free Organisms; Succinic Acid; Trachea | 2006 |
Different mechanisms between thromboxane A2- and leukotriene D4-induced nasal blockage in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Blood Vessels; Disease Models, Animal; Drug Synergism; Guinea Pigs; Leukotriene D4; Male; Models, Biological; Naphazoline; Nasal Mucosa; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Pollen; Rhinitis, Allergic, Seasonal; Thromboxane A2 | 2006 |
Effects of acute hypobaric hypoxia on the nitric oxide system of the rat cerebral cortex: Protective role of nitric oxide inhibitors.
Topics: Altitude; Analysis of Variance; Animals; Blotting, Western; Calcium; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Hypoxia; Immunohistochemistry; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Time Factors; Tyrosine | 2006 |
[Inhibitor of nitric oxide synthase on the denervated muscle atrophy].
Topics: Animals; Disease Models, Animal; Muscle, Skeletal; Muscular Atrophy; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2006 |
Hindlimb claudication reflects impaired nitric oxide-dependent revascularization after ischemia.
Topics: Animals; Arterial Occlusive Diseases; Biomechanical Phenomena; Blood Flow Velocity; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Gait; Hindlimb; Intermittent Claudication; Ischemia; Locomotion; Male; Muscle, Skeletal; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peripheral Vascular Diseases; Rats; Rats, Wistar; Recovery of Function; RNA, Messenger; Time Factors | 2007 |
Comparative effects of selective and non-selective nitric oxide synthase inhibition in gentamicin-induced rat nephrotoxicity.
Topics: Acetylglucosaminidase; Animals; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Gentamicins; Glomerular Filtration Rate; Kidney; Kidney Diseases; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2007 |
Differential effects of low and high dose folic acid on endothelial dysfunction in a murine model of mild hyperhomocysteinaemia.
Topics: Animals; Clotrimazole; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mesenteric Arteries; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Vasodilation; Vasodilator Agents | 2006 |
Role of endogenous nitric oxide (NO) and NO synthases in healing of indomethacin-induced intestinal ulcers in rats.
Topics: Animals; Disease Models, Animal; Duodenal Ulcer; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Indomethacin; Injections, Subcutaneous; Intestine, Small; Isoenzymes; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; RNA, Messenger; Wound Healing | 2007 |
The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE-0991 attenuates heart failure induced by myocardial infarction.
Topics: Angiotensin II; Animals; Cardiac Output, Low; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Imidazoles; Ligation; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Time Factors; Vasoconstriction; Vasodilator Agents; Ventricular Function, Left | 2007 |
Cardiovascular responses to oxygen inhalation after hemorrhage in anesthetized rats: hyperoxic vasoconstriction.
Topics: Acidosis, Lactic; Administration, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Cardiovascular System; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemorrhage; Hyperoxia; Lactic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Risk Assessment; Time Factors; Vascular Resistance; Vasoconstriction | 2007 |
NO synthase uncoupling in the kidney of Dahl S rats: role of dihydrobiopterin.
Topics: Animals; Biopterins; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Kidney; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats; Rats, Inbred Dahl; Superoxides | 2006 |
The involvement of nitric oxide in the anticonvulsant effects of alpha-tocopherol on penicillin-induced epileptiform activity in rats.
Topics: alpha-Tocopherol; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillins; Rats; Rats, Wistar; Seizures | 2007 |
Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Fetus; HSP90 Heat-Shock Proteins; Humans; Infant, Newborn; Ligation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oxidative Stress; Persistent Fetal Circulation Syndrome; Pregnancy; Pulmonary Artery; S-Nitroso-N-Acetylpenicillamine; Sheep; Superoxides; Tyrosine; Vasodilation | 2007 |
Protective effect of arginine on oxidative stress in transgenic sickle mouse models.
Topics: Anemia, Sickle Cell; Animals; Antioxidants; Arginine; Catalase; Dietary Supplements; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Superoxide Dismutase | 2006 |
Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats.
Topics: Acetylcholine; Animals; Biological Factors; Catalase; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Microcirculation; Microscopy, Video; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2007 |
Modifications produced by indomethacin and L-NAME in the effect of ultralow-dose aspirin on platelet activity in portal hypertension.
Topics: Animals; Aspirin; Blood Coagulation Tests; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Interactions; Hypertension, Portal; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activation; Platelet Function Tests; Rats; Rats, Wistar; Splanchnic Circulation; Thrombosis | 2006 |
Contrasting effects of chronic hypoxia and nitric oxide synthase inhibition on circulating angiogenic factors in a rat model of growth restriction.
Topics: Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Female; Fetal Growth Retardation; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Placenta Growth Factor; Pregnancy; Pregnancy Proteins; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 2007 |
Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro.
Topics: Animals; Arachidonic Acids; Benzoxazines; Blood Pressure; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Heart Rate; Hypertension; Male; Mesenteric Arteries; Morpholines; Muscle, Skeletal; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Renal Circulation; Splanchnic Circulation; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents | 2007 |
Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antihypertensive Agents; Carbolines; Cardiomyopathies; Cardiovascular Agents; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Doxorubicin; Endothelium, Vascular; Enzyme Inhibitors; Erectile Dysfunction; Heart Failure; Humans; Hypertension; Hypertension, Pulmonary; Imidazoles; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents; Ventricular Remodeling | 2007 |
Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat.
Topics: Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Cardiovascular Agents; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Hypertension; Male; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Severity of Illness Index; Sildenafil Citrate; Sulfones; Time Factors; Vasodilation; Vasodilator Agents; Ventricular Function | 2007 |
Sex differences in modulating blood brain barrier permeability by NO in pentylenetetrazol-induced epileptic seizures.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Convulsants; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Enzyme Inhibitors; Epilepsy; Female; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Pentylenetetrazole; Rats; Rats, Wistar; Sex Factors | 2007 |
Sympathetic activation in rats with L-NAME-induced hypertension.
Topics: Animals; Cardiac Output; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sympathetic Nervous System; Vascular Resistance | 2007 |
Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome.
Topics: Acetylcholine; Age Factors; Animals; Aorta, Abdominal; Aorta, Thoracic; Calcium; Cyclic GMP; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Enzyme Inhibitors; Fibrillin-1; Fibrillins; Marfan Syndrome; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vasodilation; Vasodilator Agents | 2007 |
The lack of effects of zinc and nitric oxide in initial state of pilocarpine-induced seizures.
Topics: Animals; Behavior, Animal; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Enzyme Inhibitors; Functional Laterality; Hippocampus; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Zinc | 2007 |
TNF-alpha contributes to endothelial dysfunction by upregulating arginase in ischemia/reperfusion injury.
Topics: Acetylcholine; Animals; Arginase; Arginine; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Mice; Mice, Knockout; Mice, Transgenic; Myocardial Reperfusion Injury; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Receptors, Tumor Necrosis Factor; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2007 |
Inhibition of peroxynitrite precursors, NO and O2, at the onset of reperfusion improves myocardial recovery.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Male; Molsidomine; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen Consumption; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Treatment Outcome; Ventricular Function, Left | 2007 |
Myocardial release of nitric oxide during ischaemia and reperfusion: effects of L-arginine and hypercholesterolaemia.
Topics: Analysis of Variance; Animals; Arginine; Coronary Circulation; Disease Models, Animal; Enzyme Inhibitors; Hypercholesterolemia; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Research Design; Time Factors; Ventricular Pressure | 2007 |
Reduced photoreceptor damage after photodynamic therapy through blockade of nitric oxide synthase in a model of choroidal neovascularization.
Topics: Animals; Apoptosis; Caspase 3; Choroidal Neovascularization; Disease Models, Animal; Enzyme Inhibitors; Fluorescein Angiography; Fluorescent Antibody Technique, Indirect; In Situ Nick-End Labeling; Injections, Intraperitoneal; Macaca fascicularis; Macrophages; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Photochemotherapy; Photoreceptor Cells, Vertebrate; Photosensitizing Agents; Porphyrins; Rats; Rats, Inbred BN; Retinal Degeneration; Verteporfin | 2007 |
Nitric oxide synthase isoform inhibition before whole body ischemia reperfusion in pigs: vital or protective?
Topics: Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Electric Countershock; Enzyme Inhibitors; Imidazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Reperfusion Injury; Swine; Ventricular Fibrillation | 2007 |
In which period of injury is resveratrol treatment effective: ischemia or reperfusion?
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Hindlimb; Immunohistochemistry; Ischemic Preconditioning; Lumbar Vertebrae; Malondialdehyde; Microscopy, Electron; Movement; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Peroxidase; Rabbits; Recovery of Function; Reperfusion; Reperfusion Injury; Resveratrol; Spinal Cord Injuries; Stilbenes; Time Factors; Treatment Outcome | 2007 |
Modulation of aortic vascular reactivity by sex hormones in a male rat model of metabolic syndrome.
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Estradiol; Gonadal Steroid Hormones; Indomethacin; Male; Metabolic Syndrome; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Sucrose; Testosterone | 2007 |
Ncx (Enx, Hox11L.1) is required for neuronal cell death in enteric ganglia of mice.
Topics: Animals; Animals, Newborn; Animals, Suckling; Apoptosis; Barium Compounds; Caspase 3; Cell Count; Cell Lineage; Cell Movement; Chlorides; Coloring Agents; Disease Models, Animal; Enteric Nervous System; Enzyme Induction; Gastrointestinal Transit; Gene Expression Regulation, Developmental; Genes, bcl-2; Homeodomain Proteins; In Situ Nick-End Labeling; Indoles; Intestine, Small; Megacolon; Mice; Mice, Knockout; NADPH Dehydrogenase; Neural Crest; Neurons; NG-Nitroarginine Methyl Ester; Organometallic Compounds; Proto-Oncogene Proteins c-bcl-2; Staining and Labeling; Stomach | 2007 |
Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Animal; Enzyme Inhibitors; Hepatic Encephalopathy; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Failure, Acute; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Simvastatin; Thioacetamide; Time Factors | 2008 |
Effect of maturation on renal Na+/K+-atpase and its susceptibility to nitric oxide-deficient hypertension in rats.
Topics: Adenosine Triphosphate; Age Factors; Aging; Animals; Binding Sites; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Kinetics; Male; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2007 |
Ventilatory response to hypoxia during endotoxemia in young rats: role of nitric oxide.
Topics: Animals; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Female; Hypoxia; Indazoles; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxygen Consumption; Pulmonary Ventilation; Rats; Rats, Wistar; Time Factors | 2007 |
Role of nitric oxide in salt and water excretion in experimental hypertension in hooded (Aguti) rats.
Topics: Animals; Disease Models, Animal; Drinking; Hypertension; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Random Allocation; Rats; Sodium; Sodium Chloride; Urine | 2007 |
Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats.
Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Ligation; Male; Malondialdehyde; Middle Cerebral Artery; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Long-Evans; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2007 |
Vascular effects of long-term propranolol administration after chronic nitric oxide blockade.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta; Biological Factors; Blood Pressure; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Potassium; Propranolol; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Vasodilation; Vasodilator Agents | 2007 |
Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
Topics: Angiotensin I; Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Erectile Dysfunction; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Sodium Chloride, Dietary; Vasodilator Agents | 2007 |
Cerebral microvascular dilation during hypotension and decreased oxygen tension: a role for nNOS.
Topics: Animals; Arterioles; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Electrodes, Implanted; Endothelium, Vascular; Enzyme Inhibitors; Glutamic Acid; Guanidines; Hemorrhage; Hypotension; Male; Microelectrodes; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitro Compounds; Oxygen; Rats; Rats, Sprague-Dawley; Vasodilation | 2007 |
Antagonism of lipopolysaccharide-induced blood pressure attenuation and vascular contractility.
Topics: Animals; Aorta; Blood Pressure; Cytokines; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Isothiuronium; Lipopolysaccharides; Mice; Mice, Inbred C3H; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Point Mutation; RNA, Messenger; Shock, Septic; Signal Transduction; Sugar Phosphates; Time Factors; Toll-Like Receptor 4; Vasoconstriction | 2007 |
Acute immune and non-immune inflammatory response in spontaneously hypertensive rats and normotensive rats. Role of endogenous nitric oxide.
Topics: Anaphylaxis; Animals; Capillary Permeability; Carrageenan; Cell Migration Assays, Leukocyte; Chemotaxis, Leukocyte; Disease Models, Animal; Enzyme Inhibitors; Exudates and Transudates; Hypertension; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ovalbumin; Pleurisy; Rats; Rats, Inbred SHR; Rats, Wistar | 2007 |
The herbal medicine Tokishakuyakusan increases fetal blood glucose concentrations and growth hormone levels and improves intrauterine growth retardation induced by N(omega)-nitro-L-arginine methyl ester.
Topics: Animals; Blood Glucose; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetal Growth Retardation; Fetal Weight; Growth Hormone; Growth Hormone-Releasing Hormone; Insulin-Like Growth Factor I; Male; NG-Nitroarginine Methyl Ester; Pituitary Gland; Placenta; Placentation; Plants, Medicinal; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley | 2007 |
The role of nitric oxide in the anticonvulsant effects of pyridoxine on penicillin-induced epileptiform activity in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillins; Pyridoxine; Rats; Rats, Wistar; Somatosensory Cortex; Time Factors | 2007 |
Vasopressin response and shunting modulation in cirrhotic rats by chronic nitric oxide inhibition.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Collateral Circulation; Common Bile Duct; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Ligation; Liver; Liver Circulation; Liver Cirrhosis, Biliary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Portal Pressure; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction | 2008 |
Cutting edge: a critical role of nitric [corrected] oxide in preventing inflammation upon apoptotic cell clearance.
Topics: Animals; Apoptosis; Cell Line; Cell Movement; Cells, Cultured; Chemokine CXCL1; Chemokine CXCL2; Chemokines; Chemokines, CXC; Coculture Techniques; Disease Models, Animal; Inflammation; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Thymus Gland; Whole-Body Irradiation | 2007 |
Chronic and acute effects of different antihypertensive drugs on femoral artery relaxation of L-NAME hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Diuretics; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Femoral Artery; Heart Ventricles; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2007 |
Effect of blood pressure on L-NAME-sensitive component of vasorelaxation in adult rats.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Femoral Artery; Heart Ventricles; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Severity of Illness Index; Vasodilation; Vasodilator Agents | 2007 |
Simvastatin decreased coenzyme Q in the left ventricle and skeletal muscle but not in the brain and liver in L-NAME-induced hypertension.
Topics: Animals; Brain; Coenzymes; Disease Models, Animal; Down-Regulation; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Liver; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Simvastatin; Time Factors; Ubiquinone | 2007 |
Nitric oxide synthase inhibitor reduces noise-induced cochlear damage in guinea pigs.
Topics: Animals; Auditory Threshold; Cell Count; Cochlea; Disease Models, Animal; Follow-Up Studies; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Noise; Treatment Outcome | 2007 |
Nitric oxide synthesis blockade increases hypertrophy and cardiac fibrosis in rats submitted to aerobic training.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Endomyocardial Fibrosis; Enzyme Inhibitors; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Physical Conditioning, Animal; Rats; Rats, Wistar; Swimming | 2007 |
Nitric oxide modulates air embolism-induced lung injury in rats with normotension and hypertension.
Topics: Animals; Blood Pressure; Capillary Permeability; Cyclic GMP; Disease Models, Animal; Embolism, Air; Enzyme Inhibitors; Hypertension; Interleukin-1beta; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitroprusside; Organ Size; Perfusion; Proteins; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Respiratory Distress Syndrome; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 2007 |
Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: role of transglutaminases.
Topics: Animals; Blood Pressure; Clodronic Acid; Disease Models, Animal; Enzyme Inhibitors; Erythrocyte Deformability; Factor XIII; GTP-Binding Proteins; Hematocrit; Hypertension; Macrophages; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Glutamine gamma Glutamyltransferase 2; Research Design; Stress, Mechanical; Time Factors; Transglutaminases | 2008 |
Differential responses to various classes of drugs in a model of allergic rhinitis in guinea pigs.
Topics: Acetates; Acute Disease; Animals; Cetirizine; Cyclopropanes; Dexamethasone; Disease Models, Animal; Guinea Pigs; Heparin; Histamine H1 Antagonists; Male; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Ovalbumin; Pyrilamine; Quinolines; Rhinitis, Allergic, Seasonal; Sneezing; Sulfides | 2008 |
Acute antihypertensive action of Tempol in the spontaneously hypertensive rat.
Topics: Amitrole; Animals; Antihypertensive Agents; Blood Pressure; Buthionine Sulfoximine; Catalase; Cromakalim; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglionic Blockers; Glutathione Peroxidase; Glyburide; Heart Rate; Heme Oxygenase (Decyclizing); Hexamethonium; Hypertension; Infusions, Intravenous; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Potassium Channel Blockers; Rats; Rats, Inbred SHR; Spin Labels; Sympathetic Nervous System; Time Factors | 2007 |
Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol.
Topics: Animals; Blood Flow Velocity; Capillary Permeability; Carotid Artery, Common; Carotid Stenosis; Cell Adhesion; Cerebrovascular Circulation; Chemotaxis, Leukocyte; Disease Models, Animal; Glyburide; Glycerol; Hypertonic Solutions; Infusions, Intravenous; KATP Channels; Ligation; Male; Microcirculation; Microscopy, Fluorescence; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Papaverine; Pia Mater; Potassium Channel Blockers; Rats; Rats, Wistar; Regional Blood Flow; Vasodilation; Vasodilator Agents | 2008 |
Oxidative stress attenuates NO-induced modulation of sympathetic neurotransmission in the mesenteric arterial bed of spontaneously hypertensive rats.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Blood Pressure; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Neuropeptide Y; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Splanchnic Circulation; Superoxides; Sympathetic Nervous System | 2008 |
Combination therapy with telmisartan and spironolactone alleviates L-NAME exacerbated nephrosclerosis with an increase in PPAR-gamma and decrease in TGF-beta(1).
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Disease Models, Animal; Drug Therapy, Combination; Hypertension, Malignant; Male; Mineralocorticoid Receptor Antagonists; Nephrosclerosis; NG-Nitroarginine Methyl Ester; PPAR gamma; Rats; Rats, Inbred SHR; RNA, Messenger; Spironolactone; Telmisartan; Transforming Growth Factor beta1 | 2007 |
Nitric oxide synthesis inhibition attenuates iron-induced neurotoxicity: a stereological study.
Topics: Animals; Arginine; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Hippocampus; Iron; Male; Neurons; Neurotoxicity Syndromes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Stereotaxic Techniques | 2008 |
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Hydronephrosis; Hypertension; Indazoles; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary; Ureteral Obstruction | 2008 |
Bee venom injection produces a peripheral anti-inflammatory effect by activation of a nitric oxide-dependent spinocoeruleus pathway.
Topics: Animals; Anti-Inflammatory Agents; Bee Venoms; Disease Models, Animal; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Indazoles; Leukocytes; Locus Coeruleus; Male; Mice; Mice, Inbred ICR; Neural Pathways; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oncogene Proteins v-fos; Peripheral Nervous System Diseases; Spinal Cord; Tyrosine 3-Monooxygenase | 2008 |
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats.
Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diazoxide; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Glyburide; Guanylate Cyclase; Hemoglobins; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones | 2008 |
The effect of Nomega-nitro-L-arginine methyl ester and L-arginine on lung injury induced by abdominal aortic occlusion-reperfusion.
Topics: Animals; Aorta, Abdominal; Arginine; Arterial Occlusive Diseases; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Lung; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Spectrophotometry; Treatment Outcome; Vascular Endothelial Growth Factor A | 2008 |
Uterine artery myosin phosphatase isoform switching and increased sensitivity to SNP in a rat L-NAME model of hypertension of pregnancy.
Topics: Alternative Splicing; Animals; Arteries; Cyclic GMP; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; Furans; Hypertension, Pregnancy-Induced; Lipids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Pregnancy; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Regional Blood Flow; RNA, Messenger; Uterus | 2008 |
Seizure susceptibility alteration following reversible cholestasis in mice: Modulation by opioids and nitric oxide.
Topics: 1-Naphthylisothiocyanate; Alkaline Phosphatase; Animals; Bilirubin; Biomarkers; Cholestasis; Corn Oil; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Infusions, Intravenous; Intubation, Gastrointestinal; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Receptors, Opioid; Seizures; Time Factors | 2008 |
Defective endothelial nitric oxide synthase signaling is mediated by rho-kinase activation in rats with secondary biliary cirrhosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Aorta; Disease Models, Animal; Hemodynamics; Hypertension, Portal; Liver; Liver Cirrhosis, Biliary; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Portal Pressure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Up-Regulation | 2008 |
Protective effect of nitric oxide synthase inhibition or antioxidants on brain oxidative damage caused by intracerebroventricular arginine administration.
Topics: alpha-Tocopherol; Amidines; Analysis of Variance; Animals; Antioxidants; Arginine; Ascorbic Acid; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hippocampus; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2008 |
Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs.
Topics: Administration, Intranasal; Allergens; Allopurinol; Analysis of Variance; Animals; Antioxidants; Azoles; Cryptomeria; Disease Models, Animal; Guinea Pigs; Isoindoles; Leukotriene D4; Male; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organoselenium Compounds; Peroxynitrous Acid; Pollen; Rhinitis, Allergic, Seasonal; Xanthine Oxidase | 2008 |
Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS.
Topics: Animals; Biopterins; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Glucose; Glutathione; Mice; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Protein Binding; Rats; Rats, Zucker; Superoxides; Time Factors; Tritium | 2008 |
Restoration of female genital vasocongestive arousal responses in young and aged rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Female; Genitalia, Female; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroprusside; Ovariectomy; Rats; Rats, Wistar; Regional Blood Flow; Sexual Behavior, Animal; Vasodilation; Vasodilator Agents | 2008 |
Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension.
Topics: Animals; Arterioles; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Endothelin-1; Enzyme Inhibitors; Hypertension; Insulin; Isoproterenol; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Potassium Chloride; Prediabetic State; Rats; Rats, Zucker; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Inhibition of nitric oxide synthetase at mid-gestation in rats is associated with increases in arterial pressure, serum tumor necrosis factor-alpha, and placental apoptosis.
Topics: Animals; Apoptosis; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Gestational Age; Immunohistochemistry; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Placenta; Pre-Eclampsia; Pregnancy; Prognosis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2008 |
Pregnancy reverses hypertensive remodeling of cerebral arteries.
Topics: Adaptation, Physiological; Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Enzyme Inhibitors; Female; Homeostasis; Hypertension; Models, Cardiovascular; NG-Nitroarginine Methyl Ester; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 2008 |
Cytoprotective role of nitric oxide associated with Hsp70 expression in neonatal obstructive nephropathy.
Topics: Animals; Animals, Newborn; Apoptosis; Arginine; bcl-2-Associated X Protein; Body Weight; Caspase 3; Cytoprotection; Disease Models, Animal; Female; HSP70 Heat-Shock Proteins; Immunoprecipitation; Kidney; Kidney Diseases; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Ureteral Obstruction | 2008 |
Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin.
Topics: Animals; Blood Pressure; Breath Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Guanidines; Hypotension; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Spermine; Time Factors; Up-Regulation | 2008 |
Intermittent hypoxia modulates nitric oxide-dependent vasodilation and capillary perfusion during ischemia-reperfusion-induced damage.
Topics: Acetylcholine; Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Cheek; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Hematocrit; Hypoxia; Isothiuronium; Male; Mesocricetus; Microscopy, Video; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxidative Stress; Regional Blood Flow; Stress, Mechanical; Thiobarbituric Acid Reactive Substances; Time Factors; Vasodilation; Vasodilator Agents | 2008 |
Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia-reperfusion model.
Topics: Animals; Disease Models, Animal; Intestines; Ischemia; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Reperfusion Injury | 2008 |
Posttranslational activation of endothelial nitric oxide synthase attenuates carbon tetrachloride-induced hepatotoxicity in newborn rats.
Topics: Age Factors; Androstadienes; Animals; Animals, Newborn; Carbon Tetrachloride; Cytoprotection; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Female; Lipid Peroxidation; Liver; Liver Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Wortmannin | 2008 |
Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovariectomy; Phenylephrine; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Effects of chronic L-NAME treatment lung tissue mechanics, eosinophilic and extracellular matrix responses induced by chronic pulmonary inflammation.
Topics: Animals; Asthma; Biomechanical Phenomena; Disease Models, Animal; Eosinophils; Extracellular Matrix; Guinea Pigs; Lung; Male; NG-Nitroarginine Methyl Ester; Pneumonia | 2008 |
Regulatory role of nitric oxide on the cardiac Na, K-ATPase in hypertension.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Blood Pressure; Disease Models, Animal; Energy Metabolism; Enzyme Inhibitors; Hypertension; Kinetics; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2008 |
Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart.
Topics: Aldehydes; Amidines; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzylamines; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Hypertension; Losartan; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Tiopronin; Up-Regulation; Ventricular Function, Left | 2008 |
Nitric oxide deficiency and increased adenosine response of afferent arterioles in hydronephrotic mice with hypertension.
Topics: Adenosine; Angiotensin II; Animals; Arterioles; Disease Models, Animal; Enzyme Inhibitors; Hydronephrosis; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Transforming Growth Factors; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Impaired functions of neural stem cells by abnormal nitric oxide-mediated signaling in an in vitro model of Niemann-Pick type C disease.
Topics: Animals; Caspase 3; Cell Death; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homozygote; Intermediate Filament Proteins; Intracellular Signaling Peptides and Proteins; Mice; Nerve Degeneration; Nerve Tissue Proteins; Nestin; Neurons; NG-Nitroarginine Methyl Ester; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Nitric Oxide; Proteins; Signal Transduction; Stem Cells | 2008 |
Tx2-6 toxin of the Phoneutria nigriventer spider potentiates rat erectile function.
Topics: Animals; Disease Models, Animal; Drug Synergism; Electric Stimulation; Erectile Dysfunction; Hypertension; Male; Neuropeptides; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penile Erection; Penis; Rats; Rats, Wistar; Spider Venoms; Spiders | 2008 |
High-fat diet-induced obesity leads to increased NO sensitivity of rat coronary arterioles: role of soluble guanylate cyclase activation.
Topics: Acetylcholine; Adaptation, Physiological; Animals; Arterioles; Blotting, Western; Coronary Vessels; Cyclic GMP; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Guanylate Cyclase; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Nitroso Compounds; Obesity; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2008 |
p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.
Topics: Abdomen; Animals; Calmodulin; Cardiotonic Agents; Caveolin 1; Chemokine CXCL1; Chemokine CXCL2; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Estradiol; Heart Diseases; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Mitogen-Activated Protein Kinase 11; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peroxidase; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation; Ventricular Function | 2008 |
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.
Topics: Amiloride; Amino Acids, Cyclic; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Synergism; Homeostasis; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Ketoglutarate Dehydrogenase Complex; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Sodium-Calcium Exchanger | 2008 |
Effect of adrenomedullin on hepatic damage in hepatic ischaemia/reperfusion injury in rats.
Topics: Adrenomedullin; Animals; Arginase; Aspartate Aminotransferases; Blood Flow Velocity; Disease Models, Animal; Drug Therapy, Combination; Endothelin-1; Enzyme Inhibitors; Interleukin-1beta; Liver Diseases; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2008 |
Alpha2-antiplasmin is a critical regulator of angiotensin II-mediated vascular remodeling.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Collagen Type I; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Eye Proteins; Fibrosis; Gelatinases; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Growth Factors; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Serpins; Thoracic Arteries; Tumor Suppressor Protein p53 | 2008 |
Chronic L-arginine administration increases oxidative and nitrosative stress in rat hyperoxaluric kidneys and excessive crystal deposition.
Topics: Animals; Arginine; Calcium Oxalate; Crystallization; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxyproline; Hyperoxaluria; Kidney; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides | 2008 |
Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.
Topics: Acetylcholine; Anemia, Sickle Cell; Animals; Arginine; Citrulline; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Globins; Heme Oxygenase-1; Hemodynamics; Hemoglobins; Hemolysis; Humans; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Tyrosine; Vasodilator Agents | 2008 |
A new approach for the pathogenesis of human African trypanosomiasis.
Topics: Animals; Arginine; Brain; CD8-Positive T-Lymphocytes; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Sensory; Ganglia, Spinal; Growth Substances; Hot Temperature; Humans; Hyperalgesia; Injections, Spinal; Interferon-gamma; Mice; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nociceptors; Rats; Trypanosoma brucei brucei; Trypanosomiasis, African | 1994 |
Intrahippocampal administration of the NO synthase inhibitor L-NAME prevents working memory deficits in rats exposed to transient cerebral ischemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Disease Models, Animal; Hippocampus; Injections; Ischemic Attack, Transient; Male; Memory Disorders; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 1994 |
Activity of the L-arginine/nitric oxide pathway and endothelin-1 in experimental heart failure.
Topics: Acetylcholine; Animals; Aorta; Arginine; Body Weight; Cricetinae; Disease Models, Animal; Endothelins; Endothelium, Vascular; Heart Failure; In Vitro Techniques; Male; Mesenteric Arteries; Mesocricetus; Muscle Relaxation; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Organ Size; Vascular Resistance | 1994 |
Modulation of hemodynamics and organ blood flow by nitric oxide synthase inhibition is not altered in normotensive, septic rats.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cecum; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodynamics; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sepsis; Wakefulness | 1994 |
Spinal mediators of hyperalgesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arginine; Calcium; Cycloleucine; Disease Models, Animal; Excitatory Amino Acids; Hot Temperature; Hyperalgesia; Male; N-Methylaspartate; Neuronal Plasticity; Neurons, Afferent; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stress, Mechanical | 1994 |
[Study on roles of L-arginine to nitric oxide pathway for the cardiovascular control: assessment with a new model of hypertension produced by the chronic administration of nitric oxide synthase inhibitor].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Chronic Disease; Disease Models, Animal; Hemodynamics; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Sympathetic Nervous System | 1994 |
Increased nitric oxide production in endotoxin-induced uveitis. Reduction of uveitis by an inhibitor of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Aqueous Humor; Arginine; Base Sequence; Disease Models, Animal; DNA Primers; Endotoxins; Male; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Rats; Rats, Inbred BN; Rats, Inbred Lew; RNA, Messenger; Uveitis; Vitreous Body | 1995 |
Dose-dependent anticonvulsant and proconvulsant effects of nitric oxide synthase inhibitors on seizure threshold in a cortical stimulation model in rats.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Epilepsy; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Valproic Acid | 1995 |
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Guanidines; Heart Rate; Hypotension; Lipopolysaccharides; Male; Mice; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Wistar; Shock, Septic; Time Factors | 1995 |
Assessment of renal dopaminergic system activity in the nitric oxide-deprived hypertensive rat model.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Disease Models, Animal; Dopamine; Drinking; Heart Rate; Hypertension; Kidney; Kinetics; Levodopa; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Urination | 1995 |
The role of inducible nitric oxide synthase in vascular hyporeactivity of endotoxin-treated and portal hypertensive rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Disease Models, Animal; Endotoxins; Enzyme Induction; Escherichia coli; Guanidines; Hypertension, Portal; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1995 |
Effects of nitric oxide synthase inhibition on regional blood flow in a porcine model of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiac Output; Carotid Arteries; Disease Models, Animal; Escherichia coli Infections; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Regional Blood Flow; Renal Circulation; Resuscitation; Shock, Septic; Splanchnic Circulation; Swine | 1995 |
Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity.
Topics: Animals; Arginine; Calmodulin-Binding Proteins; Capsaicin; Colitis; Disease Models, Animal; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 1995 |
Impairment of endothelium-dependent vasorelaxation in chronic two-kidney, one clip hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Chronic Disease; Disease Models, Animal; Hypertension, Renal; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilation | 1995 |
Structure and function of the rat basilar artery during chronic nitric oxide synthase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Basilar Artery; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Hypertension; Image Processing, Computer-Assisted; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Serotonin; Vasodilator Agents; Verapamil; Video Recording | 1995 |
Effect of inhibiting NO synthesis on hippocampal extracellular glutamate concentration in seizures induced by kainic acid.
Topics: Animals; Arginine; Blood Glucose; Disease Models, Animal; Electrophysiology; Glutamic Acid; Hippocampus; Kainic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Seizures; Time Factors | 1995 |
Role of nitric oxide in porcine liver circulation under normal and endotoxemic conditions.
Topics: Animals; Arginine; Blood Flow Velocity; Disease Models, Animal; Endotoxins; Hepatic Artery; Liver Circulation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Portal Vein; Shock, Septic; Swine | 1995 |
The role of endothelin and nitric oxide in modulation of normal and spastic cerebral vascular tone in the dog.
Topics: Amino Acid Sequence; Animals; Arginine; Basilar Artery; Cisterna Magna; Disease Models, Animal; Dogs; Endothelins; Female; Immunohistochemistry; Ischemic Attack, Transient; Male; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides, Cyclic; Radiography; Subarachnoid Hemorrhage | 1995 |
Nitric oxide production in experimental alcoholic liver disease in the rat: role in protection from injury.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Liver; Liver Diseases, Alcoholic; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar | 1995 |
Amelioration of chronic ileitis by nitric oxide synthase inhibition.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chronic Disease; Disease Models, Animal; Guinea Pigs; Ileitis; Ileum; Intestinal Mucosa; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Peroxidase; Therapeutic Irrigation; Trinitrobenzenesulfonic Acid | 1993 |
Control of renin gene expression in 2 kidney-1 clip rats.
Topics: Animals; Arginine; Denervation; Disease Models, Animal; Furosemide; Gene Expression Regulation; Hypertension, Renovascular; Kidney; Male; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Antagonists; Ramipril; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1994 |
Renal hypertensive angiopathy. Comparison between chronic NO suppression and DOCA-salt intoxication.
Topics: Animals; Aorta; Arginine; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclic GMP; Desoxycorticosterone; Disease Models, Animal; Hypertension, Renal; Hypertrophy, Left Ventricular; Male; Mortality; NG-Nitroarginine Methyl Ester; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System | 1995 |
Nitric oxide mediates neuropathic pain behavior in peripherally denervated rats.
Topics: Animals; Arginine; Behavior, Animal; Cyclic AMP; Denervation; Disease Models, Animal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Peripheral Nerves; Phantom Limb; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Stereoisomerism; Synaptic Transmission; Time Factors | 1995 |
Endotoxin-stimulated nitric oxide production increases injury and reduces rat liver chemiluminescence during reperfusion.
Topics: Animals; Arginine; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Lipopolysaccharides; Liver Diseases; Luminescent Measurements; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 1995 |
Modulation of granuloma formation by endogenous nitric oxide.
Topics: Animals; Arginine; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Granuloma; Inflammation; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Polymers; Prostheses and Implants; Rats; Rats, Wistar; Stereoisomerism | 1994 |
The pulmonary effect of nitric oxide synthase inhibition following endotoxemia in a swine model.
Topics: Administration, Inhalation; Animals; Arginine; Bacteremia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli Infections; Female; Hypertension, Pulmonary; Hypoxia; Lung Volume Measurements; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Edema; Pulmonary Wedge Pressure; Random Allocation; Swine | 1994 |
The inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescence.
Topics: Administration, Inhalation; Animals; Arginine; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Inflammation; Luminescent Measurements; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Nitrates; Rats; Rats, Inbred F344; Silicon Dioxide; Superoxide Dismutase | 1994 |
The role of nitric oxide in uveitis.
Topics: Animals; Aqueous Humor; Arginine; Bacterial Toxins; Disease Models, Animal; Endotoxins; Eye Proteins; Leukocyte Count; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred Lew; Uveitis, Anterior | 1994 |
Effect of nitric oxide and prostaglandins on renal function in insulin-resistant hypertensive dogs.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Diuresis; Dogs; Fructose; Glomerular Filtration Rate; Hypertension; Insulin Resistance; Kidney; Male; Meclofenamic Acid; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Renal Circulation | 1993 |
Effects of inhaled nitric oxide on pulmonary hemodynamics and gas exchange in an ovine model of ARDS.
Topics: Administration, Inhalation; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen Consumption; Pulmonary Circulation; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Respiratory Mechanics; Sheep; Therapeutic Irrigation | 1994 |
Endogenous nitric oxide protects against platelet-activating factor-induced bowel injury in the rat.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enterocolitis, Pseudomembranous; Hematocrit; Intestines; Male; Mesenteric Artery, Superior; Necrosis; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Superoxides | 1993 |
Atrial natriuretic factor influences in vivo plasma, lung and aortic wall cGMP concentrations differently.
Topics: Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cyclic GMP; Disease Models, Animal; Infusions, Intravenous; Lung; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Renin | 1993 |
Subarachnoid hemorrhage and endothelial L-arginine pathway in small brain stem arteries in dogs.
Topics: Animals; Arginine; Arterioles; Bradykinin; Brain Stem; Calcimycin; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Male; NG-Nitroarginine Methyl Ester; Subarachnoid Hemorrhage; Vasodilation; Vasopressins | 1993 |
Experimental neuronal injury in the newborn lamb: a comparison of N-methyl-D-aspartic acid receptor blockade and nitric oxide synthesis inhibition on lesion size and cerebral hyperemia.
Topics: Animals; Animals, Newborn; Arginine; Brain Diseases; Cattle; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hemodynamics; Hyperemia; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Sheep | 1995 |
L-NAME reduces infarct volume in a filament model of transient middle cerebral artery occlusion in the rat pup.
Topics: Animals; Arginine; Arterial Occlusive Diseases; Cerebral Arteries; Cerebral Infarction; Disease Models, Animal; Ischemic Attack, Transient; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nylons; Rats; Rats, Inbred SHR | 1995 |
Perinatal nitric oxide synthase inhibition retards neonatal growth by inducing hypertrophic pyloric stenosis in rats.
Topics: Animals; Animals, Newborn; Arginine; Body Weight; Disease Models, Animal; Embryonic and Fetal Development; Female; Growth; Guanidines; Hypertrophy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Pyloric Stenosis; Rats | 1995 |
[Effect of chronic inhibition of nitric oxide synthesis on vascular structure: remodeling or growth?].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Basilar Artery; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Hypertension; Indoles; Muscle Development; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Verapamil | 1995 |
The role of nitric oxide in facial motoneuronal death.
Topics: Animals; Arginine; Cell Death; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Facial Nerve; Histocytochemistry; Male; Motor Neurons; NADPH Dehydrogenase; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Effects of chronic nitric oxide synthase inhibition on TNB-induced colitis in rats.
Topics: Animals; Arginine; Body Weight; Colitis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infusion Pumps, Implantable; Injections, Subcutaneous; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 1995 |
The role of nitric oxide and sulphydryls in gastric mucosal protection induced by sodium cromoglycate in rats.
Topics: Animals; Arginine; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Ethylmaleimide; Gastric Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfhydryl Compounds | 1995 |
Endothelium-derived nitric oxide does not modulate metabolic coronary vasodilation induced by tachycardia in dogs.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Heart; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxygen Consumption; Tachycardia; Vasodilation | 1995 |
Inhibition of nitric oxide synthase during hemorrhagic shock increases hepatic injury.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Infusions, Intravenous; Liver; Liver Circulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Time Factors | 1995 |
Analysis of responses to pentoxifylline in the pulmonary vascular bed of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Bronchodilator Agents; Cats; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Isoproterenol; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentoxifylline; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Thromboxane A2; Vasodilator Agents | 1996 |
Effect of halothane on phenylephrine-induced vascular smooth muscle contractions in endotoxin-exposed rat aortic rings.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Lipopolysaccharides; Logistic Models; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstrictor Agents | 1996 |
Endothelium-derived relaxing factor (nitric oxide) has a tonic vasodilating action on coronary collateral vessels.
Topics: Animals; Arginine; Collateral Circulation; Coronary Vessels; Dilatation, Pathologic; Disease Models, Animal; Dogs; Female; Hemodynamics; Humans; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 1996 |
Aggravation of experimental allergic encephalomyelitis (EAE) by administration of nitric oxide (NO) synthase inhibitors.
Topics: Animals; Arginine; Brain; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Guinea Pigs; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred Lew | 1996 |
Endogenous nitric oxide and pulmonary vascular tone in the neonate.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Extracorporeal Membrane Oxygenation; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Respiratory Mechanics; Swine; Vascular Resistance | 1996 |
Toxic dilatation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase.
Topics: Animals; Arginine; Colitis; Colon; Dexamethasone; Dilatation; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Hypoxanthines; Inflammation; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 1996 |
Effects of three inhibitors of nitric oxide synthase on host resistance to bacterial infection.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli Infections; Female; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Prospective Studies; Random Allocation | 1996 |
Correlation between brain nitric oxide synthase activity and opiate withdrawal.
Topics: Animals; Arginine; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Injections, Subcutaneous; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Stereoisomerism; Substance Withdrawal Syndrome | 1996 |
A selective inhibitor of inducible in nitric oxide synthase prolongs survival in a rat model of bacterial peritonitis: comparison with two nonselective strategies.
Topics: Animals; Anti-Bacterial Agents; Arginine; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli Infections; Gram-Negative Bacterial Infections; Hemoglobins; Leukocyte Count; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis | 1996 |
Nitric oxide donor alleviates ovariectomy-induced bone loss.
Topics: Absorptiometry, Photon; Analysis of Variance; Animals; Arginine; Bone Density; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley | 1996 |
Vasoconstrictor responsiveness of the rat mesenteric arterial bed in cirrhosis.
Topics: Adenosine Triphosphate; Animals; Arginine; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Liver Cirrhosis, Experimental; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Phenobarbital; Rats; Rats, Wistar; Vasopressins | 1996 |
Inhibition of NO synthase in the posterior hypothalamus increases blood pressure in the rat.
Topics: Animals; Arginine; Blood Pressure; Data Interpretation, Statistical; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Hypothalamus, Posterior; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Comparison between conventional hemodynamic monitoring and polarographic tissue pO2-monitoring of the liver in early septicemia of the pig.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Hemodynamics; Liver; Liver Circulation; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Oxygen; Oxygen Consumption; Polarography; Sepsis; Shock, Septic; Swine | 1996 |
Cerebral metabolic recovery from deep hypothermic circulatory arrest after treatment with arginine and nitro-arginine methyl ester.
Topics: Animals; Arginine; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Electron Transport Complex IV; Enzyme Inhibitors; Glucose; Heart Arrest, Induced; Hemoglobins; Hydrogen-Ion Concentration; Hypothermia, Induced; Injections, Intravenous; Magnetic Resonance Spectroscopy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen Consumption; Oxyhemoglobins; Phosphates; Reperfusion; Rewarming; Spectrophotometry, Infrared; Swine | 1996 |
Comparison of sodium pentobarbitone and urethane anaesthesia in a rat model of coronary artery occlusion and reperfusion arrhythmias: interaction with L-NAME.
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Male; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentobarbital; Rats; Rats, Sprague-Dawley; Urethane | 1996 |
Effect of terlipressin on in vitro vascular hyporeactivity of portal hypertensive rats.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Portal; In Vitro Techniques; Lypressin; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Terlipressin; Vasodilation | 1996 |
Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Gerbillinae; Indazoles; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Quinoxalines | 1996 |
Chronic endotoxemia and endothelium-dependent vasodilation in coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Body Temperature; Body Weight; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Hemodynamics; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Rabbits; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
A comparison between the acute effects of nitric oxide synthase inhibition and fluid resuscitation on myocardial function and metabolism in entotoxemic dogs.
Topics: Animals; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Fluid Therapy; Hemodynamics; Lipopolysaccharides; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Resuscitation; Shock, Septic | 1996 |
Circuit factors in the high cardiac output of sepsis.
Topics: Analysis of Variance; Animals; Blood Pressure; Cardiac Output, High; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Fluid Therapy; Hemodynamics; NG-Nitroarginine Methyl Ester; Sepsis; Swine; Vascular Capacitance | 1996 |
Beneficial effects of amlodipine in a murine model of congestive heart failure induced by viral myocarditis. A possible mechanism through inhibition of nitric oxide production.
Topics: Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Cardiovirus Infections; Disease Models, Animal; Encephalomyocarditis virus; Heart; Heart Failure; Male; Mice; Mice, Inbred DBA; Myocarditis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size | 1997 |
Arthus C. Corcoran Memorial Lecture. Influence of nitric oxide and angiotensin II on renal involvement in hypertension.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Diuretics; Endothelium, Vascular; Humans; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Sodium Chloride Symporter Inhibitors | 1997 |
Endothelial stunning and myocyte recovery after reperfusion of jeopardized muscle: a role of L-arginine blood cardioplegia.
Topics: Animals; Cardioplegic Solutions; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Myocardial Stunning; Myocardium; NG-Nitroarginine Methyl Ester; Peroxidase; Swine; Swine, Miniature; Vasodilation | 1997 |
Protective action of epidermal growth factor and a fraction from Triticum vulgare extract in mouse tail necrosis.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Ischemia; Male; Mice; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Plant Extracts; Reperfusion Injury; Tail; Tritium | 1997 |
Captopril prevents NO-deficient hypertension and left ventricular hypertrophy without affecting nitric oxide synthase activity in rats.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Enzyme Inhibitors; Evaluation Studies as Topic; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Time Factors | 1996 |
Role of nitric oxide in acute renal failure.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Hemodynamics; Kidney Tubules, Proximal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats | 1997 |
Dual action of nitric oxide on airway plasma leakage.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Disease Models, Animal; Enzyme Inhibitors; Extravasation of Diagnostic and Therapeutic Materials; Humans; Lipopolysaccharides; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Trachea | 1997 |
Effects of N omega-nitro-L-arginine methyl ester on the endotoxin-induced disseminated intravascular coagulation in porcine septic shock.
Topics: Animals; Disease Models, Animal; Disseminated Intravascular Coagulation; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Female; Hemodynamics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Severity of Illness Index; Shock, Septic; Swine | 1997 |
Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Indazoles; Infusions, Intravenous; Injections, Intravenous; Isotope Labeling; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation; Vasodilator Agents | 1997 |
Antiedematous effects of combination therapies with the leukotriene synthesis inhibitor BAY X 1005 in the archidonic acid-induced mouse ear inflammation test.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Disease Models, Animal; Drug Therapy, Combination; Ear; Edema; Female; Histamine H1 Antagonists; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Methysergide; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrilamine; Quinolines; Serotonin Antagonists | 1997 |
The role of nitric oxide in modulating ischaemia-induced arrhythmias in rats.
Topics: Analysis of Variance; Animals; Arrhythmias, Cardiac; Blood Pressure; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; Male; Methylene Blue; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sydnones; Vasodilator Agents; Ventricular Fibrillation | 1997 |
Attenuated central pressor response to nitric oxide synthesis inhibition in chronic renal failure rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Enzyme Inhibitors; Kidney Failure, Chronic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reference Values | 1997 |
Changes of the plasma endothelin in adaptation to increased salt intake in rats.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Extracellular Space; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reference Values; Sodium, Dietary; Urine | 1997 |
Nitric oxide synthase inhibition in a spontaneously hypertensive rat model of diabetic nephropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR | 1997 |
SA4503, a novel cognitive enhancer with sigma1 receptor agonist properties, facilitates NMDA receptor-dependent learning in mice.
Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Cognition; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Maze Learning; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Progesterone; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spatial Behavior | 1997 |
Prevention of radiocontrast-induced nephropathy by adenosine antagonists in rats with chronic nitric oxide deficiency.
Topics: Acute Kidney Injury; Adenosine; Animals; Blood Pressure; Contrast Media; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1997 |
The role of endothelial nitric oxide synthase in the pathogenesis of a rat model of hepatopulmonary syndrome.
Topics: Acetylcholine; Animals; Common Bile Duct; Disease Models, Animal; Endothelium, Vascular; Hypoxia; Immunoblotting; Immunohistochemistry; Ligation; Liver Diseases; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Gas Exchange; Rats; Rats, Sprague-Dawley; Syndrome; Vasodilation | 1997 |
Concomitant treatment with a 5-lipoxygenase inhibitor improves the anti-inflammatory effect of the inhibition of nitric oxide synthase during the early phase of endotoxin-induced uveitis in the rabbit.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aqueous Humor; Ciliary Body; Dimethyl Sulfoxide; Dinoprostone; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Endotoxins; Enzyme Inhibitors; Interleukin-1; Iris; Leukotriene B4; Lipoxygenase Inhibitors; Male; Masoprocol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxidase; Rabbits; Salmonella typhimurium; Treatment Outcome; Uveitis | 1997 |
Inhibition of nitric oxide modulates the effect of oral arginine supplementation in acute liver injury.
Topics: Acute Disease; Administration, Oral; Alanine Transaminase; Analysis of Variance; Animals; Arginine; Aspartate Aminotransferases; Bacterial Translocation; Bilirubin; Chemical and Drug Induced Liver Injury; Colony Count, Microbial; Disease Models, Animal; DNA; Enzyme Inhibitors; Food, Fortified; Galactosamine; Intestinal Mucosa; Liver Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; RNA | 1997 |
[The role of nitric oxide in mercury chloride-induced vasculitis in the brown Norway rat].
Topics: Animals; Autoantibodies; Disease Models, Animal; Kidney; Male; Mercuric Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred BN; Vasculitis | 1997 |
Attenuated inhibition of adrenergic contraction by nitric oxide in injured guinea pig femoral artery.
Topics: Acetylcholine; Adrenergic Fibers; Animals; Arginine; Capsaicin; Catheterization; Disease Models, Animal; Femoral Artery; Guinea Pigs; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Tunica Intima; Vasoconstriction | 1997 |
Endothelium-dependent vasodilatation produced by the L-arginine/nitric oxide pathway in normal and ischemic bone.
Topics: Acetylcholine; Animals; Disease Models, Animal; Endothelium, Vascular; Ischemia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rabbits; Tibia; Time Factors; Vasodilation; Vasodilator Agents | 1997 |
Haemodynamic effects of dopexamine and nitric oxide synthase inhibition in healthy and endotoxaemic sheep.
Topics: Adrenergic beta-Agonists; Animals; Disease Models, Animal; Dopamine; Endotoxemia; Endotoxins; Enzyme Inhibitors; Female; Hemodynamics; Infusions, Intravenous; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen Consumption; Salmonella typhi; Sheep; Vasodilator Agents | 1997 |
Myocardial reactive hyperemia in experimental chronic heart failure: evidence for the role of K+ adenosine triphosphate-dependent channels and cyclooxygenase activity.
Topics: Animals; Cardiac Output, Low; Chronic Disease; Coronary Circulation; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Glyburide; Hyperemia; Indomethacin; NG-Nitroarginine Methyl Ester; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Theophylline | 1997 |
[Contribution of L-arginine-derived nitric oxide to the structural integrity of coronary artery and cardiac interstitium, and to the regulation of sympathetic nerve activity: assessment using a rat model produced by chronic nitric oxide inhibition].
Topics: Animals; Arginine; Catecholamines; Chronic Disease; Coronary Vessels; Disease Models, Animal; Fibrosis; Heart Rate; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renin; Sympathetic Nervous System | 1997 |
Inhibition of nitric oxide synthases enhances the effect of ACTH in hemorrhagic shock.
Topics: Animals; Arginine; Cosyntropin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Shock, Hemorrhagic | 1997 |
Changes in vascular porosity and joint blood flow during development of collagen induced arthritis in the rat. Modulation by indomethacin and L-NAME.
Topics: Animals; Arthritis; Capillary Permeability; Collagen; Disease Models, Animal; Female; Hindlimb; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Prostaglandins; Rats; Regional Blood Flow | 1997 |
Sulphydryl blocker induced small intestinal inflammation in rats: a new model mimicking Crohn's disease.
Topics: Acetophenones; Animals; Antioxidants; Crohn Disease; Cyclic N-Oxides; Disease Models, Animal; Enteritis; Histamine H1 Antagonists; Iodoacetamide; Jejunal Diseases; Ketotifen; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Spin Labels; Sulfhydryl Reagents | 1997 |
Beneficial effect of ETA receptor blockade in a rat model of radiocontrast-induced nephropathy.
Topics: Acute Kidney Injury; Animals; Atrasentan; Contrast Media; Creatinine; Diatrizoate; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Antagonists; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1997 |
Regional intestinal blood flow and nitric oxide synthase inhibition during sepsis in the rat.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Intestinal Mucosa; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Time Factors | 1998 |
The role of endogenous nitric oxide in modulating ischemia-reperfusion injury in the isolated, blood-perfused rat lung.
Topics: Animals; Disease Models, Animal; Guanidines; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; RNA, Messenger; Time Factors | 1998 |
Losartan reduces constrictor responses to endothelin-1 and the thromboxane A2 analogue in aortic rings from spontaneously hypertensive rats: role of nitric oxide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents; Aorta, Thoracic; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Hypertension; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Nitric oxide mediates behavioral signs of neuropathic pain in an experimental rat model.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Male; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1998 |
Inhibition of nitric oxide synthesis aggravates myocardial ischemia in hemorrhagic shock in constant pressure model.
Topics: Adenosine Triphosphate; Animals; Aorta; Catecholamines; Disease Models, Animal; Dogs; Enzyme Inhibitors; Fluorescence; Freezing; Hemodynamics; Lactic Acid; Myocardial Ischemia; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen; Shock, Hemorrhagic | 1998 |
Effect of nitric oxide synthase inhibitor on a hyperglycemic rat model of reversible focal ischemia: detection of excitatory amino acids release and hydroxyl radical formation.
Topics: Animals; Cell Survival; Citrulline; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutamic Acid; Hydroxyl Radical; Hyperglycemia; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1998 |
Rapid development of nitric oxide-induced hyperalgesia depends on an alternate to the cGMP-mediated pathway in the rat neuropathic pain model.
Topics: Animals; Antidotes; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hemoglobins; Hot Temperature; Hyperalgesia; Ligation; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 1998 |
Oxygen delivery and consumption in surfactant-depleted newborn piglets.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Cardiac Output; Disease Models, Animal; Humans; Hypoxanthine; Infant, Newborn; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen; Oxygen Consumption; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Swine | 1998 |
N(G)-nitro-L-arginine methyl ester reduces stress-related feeding in the rat tail-pinch model.
Topics: Animals; Disease Models, Animal; Eating; Enzyme Inhibitors; Feeding Behavior; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stress, Psychological | 1998 |
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
Topics: Animals; Benzamides; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Activation; Macrophages, Peritoneal; Male; Mitochondria; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitrates; Nitric Oxide Synthase; Oxidants; Oxygen Consumption; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Shock; Zymosan | 1998 |
Effects of NG-nitro-L-arginine-methyl-ester on cardiopulmonary function and biosynthesis of cyclooxygenase products.
Topics: Animals; Disease Models, Animal; Endotoxemia; Hemodynamics; Humans; Lipopolysaccharides; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Swine | 1998 |
Intraspinal injection of adenosine agonists protect against L-NAME induced neuronal loss in the rat.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Injections, Spinal; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Rats; Rats, Long-Evans; Spinal Cord | 1998 |
Involvement of nitric oxide and prostaglandins in gastroprotection induced by bacterial lipopolysaccharide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Dexamethasone; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Ethanol; Gastric Acid; Gastric Mucosa; Gene Expression; Lipopolysaccharides; Male; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Pepsin A; Polymerase Chain Reaction; Rats; Rats, Wistar; Regional Blood Flow; RNA, Messenger; Stomach; Stomach Diseases | 1998 |
Effect of reduced cerebral perfusion pressure on cerebral blood flow following inhibition of nitric oxide synthesis.
Topics: Animals; Blood Pressure; Blood Volume; Cerebral Hemorrhage; Cerebrospinal Fluid Pressure; Cerebrovascular Circulation; Disease Models, Animal; Enzyme Inhibitors; Female; Hemostasis; Intracranial Hypertension; Intracranial Hypotension; Intracranial Pressure; Laser-Doppler Flowmetry; Male; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Swine; Time Factors; Vascular Resistance | 1998 |
Endothelial-mediated dilations following severe controlled cortical impact injury in the rat middle cerebral artery.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain Injuries; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Linear Models; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillamine; Rats; Rats, Long-Evans; Receptors, Purinergic P2; Thionucleotides; Vasodilation | 1998 |
Interactions between nitric oxide and renal nerves on pressure-diuresis and natriuresis.
Topics: Analysis of Variance; Animals; Denervation; Disease Models, Animal; Diuresis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Kidney; Kidney Function Tests; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reference Values; Regional Blood Flow | 1998 |
Nitric oxide release as an essential mitigating step in tubuloglomerular feedback: observations during intrarenal nitric oxide clamp.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Feedback; Glomerular Filtration Rate; Kidney Glomerulus; Kidney Tubules; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pressoreceptors; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation | 1998 |
Nitric oxide synthesis inhibition retards surgical reversal of one-kidney Goldblatt hypertension in rats.
Topics: Animals; Blood Pressure; Body Weight; Constriction; Disease Models, Animal; Diuresis; Electrolytes; Enzyme Inhibitors; Hypertension, Renovascular; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Renal Artery Obstruction | 1998 |
Local nitric oxide synthase activity in a model of neuropathic pain.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Immunohistochemistry; Logistic Models; Male; Metabolic Clearance Rate; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reaction Time; Regional Blood Flow; Sciatic Nerve | 1998 |
[Role of nitric oxide in pathogenesis of pregnancy induced hypertension].
Topics: Animals; Disease Models, Animal; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar | 1997 |
Increased expression of P-selectin on platelets is a risk factor for silent cerebral infarction in patients with atrial fibrillation: role of nitric oxide.
Topics: Adult; Animals; Atrial Fibrillation; Blood Platelets; Case-Control Studies; Cerebral Infarction; Disease Models, Animal; Dogs; Enzyme Inhibitors; Female; Hemodynamics; Humans; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; P-Selectin; Prevalence; Risk Factors | 1998 |
Neuronal nitric oxide synthase inhibitor, 7-nitroindazole, delays motor dysfunction and spinal motoneuron degeneration in the wobbler mouse.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Hand Strength; Indazoles; Mice; Mice, Neurologic Mutants; Motor Neuron Disease; Motor Neurons; Muscle Denervation; Muscle, Skeletal; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Size; Vacuoles | 1998 |
Stereology of the myocardium in hypertensive rats. Differences in relation to the time of inhibition of nitric oxide synthesis.
Topics: Animals; Blood Pressure; Cell Count; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart; Hypertension; Male; Microscopy, Video; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Size; Rats; Rats, Wistar; Time Factors | 1998 |
Pre-eclamptic toxemia: potential new therapy based on animal studies.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Drug Therapy, Combination; Embryonic and Fetal Development; Female; Hemodynamics; Hypertension; NG-Nitroarginine Methyl Ester; Postpartum Period; Pre-Eclampsia; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Survival Rate | 1998 |
Role of nitric oxide during the initial phase of reperfusion after retinal ischemia in the rat.
Topics: Animals; Disease Models, Animal; Electroretinography; Enzyme Inhibitors; Ischemia; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Reperfusion; Retinal Diseases; Retinal Vessels; Treatment Outcome | 1999 |
Effects of endogenous superoxide anion and nitric oxide on cholinergic constriction of normal and hyperreactive guinea pig airways.
Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Cholinergic Fibers; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Guinea Pigs; Immunization; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ovalbumin; Parasympathomimetics; Superoxide Dismutase; Superoxides; Trachea | 1998 |
Stereology and immunohistochemistry of the myocardium in experimental hypertension: long-term and low-dosage administration of inhibitor of the nitric oxide synthesis.
Topics: Animals; Cell Count; Collagen; Disease Models, Animal; Enzyme Inhibitors; Fibronectins; Hypertension; Immunohistochemistry; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Time Factors | 1999 |
Amelioration by quinapril of myocardial infarction induced by coronary occlusion/reperfusion in a rabbit model of atherosclerosis: possible mechanisms.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arterial Occlusive Diseases; Coronary Artery Disease; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Isoquinolines; Leukocytes; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; P-Selectin; Peroxidase; Quinapril; Rabbits; Receptor, Bradykinin B2; Receptors, Bradykinin; Tetrahydroisoquinolines; Ventricular Fibrillation | 1999 |
Portal veins of mice infected with Schistosoma mansoni exhibit an increased reactivity to 5-hydroxytryptamine.
Topics: Animals; Chronic Disease; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Portal Vein; Schistosomiasis mansoni; Serotonin | 1998 |
Influence of L-arginine, aminoguanidine, and NG-nitro-L-arginine methyl ester (L-name) on the survival rate in a rat model of hemorrhagic shock.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Creatinine; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Rate | 1999 |
Intestinal and hepatic perfusion and metabolism in hypodynamic endotoxic shock. Effects of nitric oxide synthase inhibition.
Topics: Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia coli; Female; Hemodynamics; Hepatic Artery; Hypertension, Pulmonary; Intestine, Small; Lactates; Lipopolysaccharides; Liver; Lung; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Portal Vein; Regional Blood Flow; Shock, Septic; Survival Rate; Swine; Vascular Resistance; Vasoconstrictor Agents; Ventricular Function, Left | 1999 |
The role of nitric oxide in neuropathic pain and neurodegeneration.
Topics: Analgesics; Animals; Disease Models, Animal; Enzyme Inhibitors; Nerve Degeneration; Nervous System Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Receptors, N-Methyl-D-Aspartate | 1998 |
Involvement of nitric oxide in cardiovascular effects of cholecystokinin (CCK) in rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Catecholamines; Cholecystokinin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Reference Values | 1998 |
Effects of sulfated cholecystokinin octapeptide and cholecystokinin tetrapeptide in rat behavior after blockade of nitric oxide synthase by L-NAME.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Disease Models, Animal; Dopamine Agents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sincalide; Tetragastrin | 1998 |
Effects of antihypertensive therapy on factors mediating endothelium-dependent relaxation in rats treated chronically with L-NAME.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Diltiazem; Disease Models, Animal; Endothelium, Vascular; Hypertension; Isoquinolines; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Quinapril; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Treatment Outcome; Vasodilation; Vasodilator Agents | 1999 |
Porcine endotoxemic shock is associated with increased expired nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Models, Animal; DNA Primers; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia coli; Hemodynamics; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Polymerase Chain Reaction; Respiration; Shock, Septic; Swine; Time Factors | 1999 |
Role of nitric oxide in restenosis after experimental balloon angioplasty in the hypercholesterolemic rabbit: effects on neointimal hyperplasia and vascular remodeling.
Topics: Angiography; Angioplasty, Balloon; Animals; Arginine; Arteriosclerosis; Disease Models, Animal; Enzyme Inhibitors; Follow-Up Studies; Hypercholesterolemia; Hyperplasia; Iliac Artery; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Secondary Prevention; Thrombosis; Tunica Intima | 1999 |
The effect of indomethacin and prostacyclin agonists on blood pressure in a rat model of preeclampsia.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; Female; Gestational Age; Iloprost; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy; Prostaglandins, Synthetic; Rats | 1999 |
Adrenomedullin attenuates the hypertension in hypertensive pregnant rats induced by N(G)-nitro-L-arginine methyl ester.
Topics: Adrenomedullin; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Body Weight; Disease Models, Animal; Enzyme Inhibitors; Female; Fetus; Hypertension; Infusions, Intravenous; NG-Nitroarginine Methyl Ester; Peptides; Pre-Eclampsia; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; RNA, Messenger; Time Factors | 1999 |
The neuronal selective nitric oxide inhibitor AR-R 17477, blocks some effects of phencyclidine, while having no observable behavioural effects when given alone.
Topics: Amidines; Animals; Antipsychotic Agents; Disease Models, Animal; Enzyme Inhibitors; Hallucinogens; Inhibitory Concentration 50; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1999 |
Pulmonary artery endothelium-dependent vasodilation is impaired in a chicken model of pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Chickens; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Ionophores; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Papaverine; Pulmonary Artery; Vasodilation; Vasodilator Agents | 1999 |
Effect of nitric oxide donors and nitric oxide synthase inhibitors in neonatal rat endotoxic shock.
Topics: Animals; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Female; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Septic; Spleen; Thiourea | 1999 |
The effect of chronic hypoxia on endothelin receptor subtype-mediated responses in rat isolated airways.
Topics: Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Receptors, Endothelin; Trachea | 1999 |
The effect of an endothelin antagonist on blood pressure in a rat model of preeclampsia.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Female; Gestational Age; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides, Cyclic; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
Expression of NOS II and its role in experimental small bowel ulceration in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Disease Models, Animal; DNA Primers; Enzyme Inhibitors; Gene Expression; Guanidines; Humans; Indomethacin; Inflammatory Bowel Diseases; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptic Ulcer; Peroxidase; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1999 |
Arterial relaxation mediated by endothelium-derived hyperpolarizing factor in hypertension induced by chronic inhibition of nitric oxide synthesis.
Topics: Acetylcholine; Animals; Apamin; Biological Factors; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Potassium; Potassium Channels; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1999 |
Nitric oxide synthase inhibition by N(G)-nitro-L-arginine methyl ester inhibits tumor-induced angiogenesis in mammary tumors.
Topics: Animals; Coloring Agents; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Female; Immunohistochemistry; Macrophages; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Cells, Cultured | 1999 |
Effect of N(G)-nitro-L-arginine methyl ester on autonomic modulation of heart rate variability during hypovolemic shock.
Topics: Animals; Blood Pressure; Blood Volume; Catecholamines; Circadian Rhythm; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; Heart; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prospective Studies; Rabbits; Shock; Sympathetic Nervous System; Vasodilation | 1999 |
Protection by shear stress from collar-induced intimal thickening: role of nitric oxide.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Carotid Artery, Internal; Cerebrovascular Circulation; Disease Models, Animal; Enzyme Inhibitors; Hyperplasia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Stress, Mechanical; Tunica Intima; Ultrasonography; Vasodilation | 1999 |
Lung injury following pulmonary resection in the isolated, blood-perfused rat lung.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Pneumonectomy; Pulmonary Artery; Pulmonary Edema; Rats; Rats, Wistar; Reperfusion Injury; Respiration, Artificial; Superoxide Dismutase | 1999 |
Antiinflammatory activity of adrenomedullin in the acetic acid peritonitis in rats.
Topics: Acetic Acid; Adrenomedullin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Humans; Mice; NG-Nitroarginine Methyl Ester; Peptides; Peritonitis; Rats; Rats, Sprague-Dawley | 1999 |
Nitric oxide synthase isoforms and glomerular hyperfiltration in early diabetic nephropathy.
Topics: Animals; Blood Pressure Determination; Blotting, Northern; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glomerular Filtration Rate; Hemodynamics; Isoenzymes; Kidney Function Tests; Kidney Glomerulus; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Streptozocin | 2000 |
Corticotrophin releasing factor attenuates NG-nitro-L-arginine methyl ester induced increases in blood pressure in the anaesthetised rat.
Topics: Anesthesia; Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reference Values; Vasodilation | 1999 |
Nitric oxide mediated vasoreactivity during fracture repair.
Topics: Acetylcholine; Animals; Blood Pressure; Bone and Bones; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Follow-Up Studies; Fracture Healing; Injections, Intravenous; Laser-Doppler Flowmetry; Male; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Regional Blood Flow; Vasodilator Agents | 1999 |
[Involvement of nitric oxide in itch-scratch response of NC mice].
Topics: Animals; Dermatitis, Atopic; Disease Models, Animal; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pruritus | 1999 |
Non-selective attention in a rat model of hyperactivity and attention deficit: subchronic methylphenydate and nitric oxide synthesis inhibitor treatment.
Topics: Animals; Attention; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Male; Methylphenidate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2000 |
Norepinephrine vs nitric oxide synthase inhibition in endotoxemia.
Topics: Animals; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Female; Hepatic Artery; Lactic Acid; Liver; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Oxygen; Portal Vein; Swine; Vascular Resistance; Vasoconstrictor Agents | 1999 |
The role of cromakalim and a nitric oxide synthase blocker in cardiac arrhythmia in the intact baboon model.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Catheterization; Cromakalim; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Papio; Propranolol; Time Factors | 2000 |
Altered vascular response to acetylcholine in conditions of endothelial damage in the isolated perfused rat stomach.
Topics: Acetylcholine; Animals; Blood Flow Velocity; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Gastric Mucosa; Gossypol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Rats; Stomach; Stomach Ulcer; Stress, Physiological; Vasodilator Agents | 2000 |
Effect of imidapril on myocardial remodeling in L-NAME-induced hypertensive rats is associated with gene expression of NOS and ACE mRNA.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Collagen; Disease Models, Animal; DNA Primers; Gene Expression; Heart Ventricles; Hypertension; Imidazoles; Imidazolidines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ventricular Remodeling | 2000 |
Continuous monitoring of nitric oxide release induced by cholecystokinin from the choledochal sphincter in guinea pigs.
Topics: Animals; Common Bile Duct; Culture Techniques; Disease Models, Animal; Gallbladder Emptying; Gastrointestinal Agents; Guinea Pigs; Male; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Reference Values; Sincalide; Sphincter of Oddi | 2000 |
Ischemic preconditioning and infarct mass: the effect of hypercholesterolemia and endothelial dysfunction.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Calcimycin; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Hypercholesterolemia; Ionophores; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Polyethylene Glycols; Potassium Chloride; Rabbits; Superoxide Dismutase; Vasodilation | 2000 |
Cyclooxygenase inhibition reduces blood pressure elevation and vascular reactivity dysfunction caused by inhibition of nitric oxide synthase in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Heart Rate; Hypertension; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Effect of cyclooxygenase and nitric oxide synthase inhibitors on tumor growth in mouse tumor models with and without cancer cachexia related to prostanoids.
Topics: Animals; Cachexia; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Female; Gene Expression Regulation; Growth Substances; Immunohistochemistry; Indans; Indomethacin; Iodine Radioisotopes; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Role of nitric oxide in pentylenetetrazol-induced seizures: age-dependent effects in the immature rat.
Topics: Age Factors; Animals; Animals, Newborn; Arginine; Brain; Catalysis; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Rats; Rats, Sprague-Dawley | 2000 |
The role of intrarenal nitric oxide in the natriuretic response to dopamine-receptor activation.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Fenoldopam; Hemodynamics; Hypertension, Renal; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Natriuresis; Nephrons; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Renal Circulation | 2000 |
The effect of intraoperative colonic lavage with NG-nitro-L-arginine methyl ester (L-NAME) on anastomotic healing in the presence of left-sided colonic obstruction in the rat.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Enzyme Inhibitors; Intestinal Obstruction; Intraoperative Period; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Reference Values; Statistics, Nonparametric; Therapeutic Irrigation; Treatment Outcome; Wound Healing | 2000 |
Effect of antihypertensive drugs on the myocardial microvessels in rats with nitric oxide blockade.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Capillaries; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Heart; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Spironolactone; Verapamil | 2000 |
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea | 2000 |
Airway reactivity, inflammatory cell influx and nitric oxide in guinea-pig airways after lipopolysaccharide inhalation.
Topics: Administration, Inhalation; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Movement; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Guinea Pigs; Leukocytes; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 2000 |
High-calcium diet enhances vasorelaxation in nitric oxide-deficient hypertension.
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium, Dietary; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelium, Vascular; Heart; Hypertension; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Organ Size; Potassium Chloride; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Oral administration of inducible nitric oxide synthase inhibitors reduces nitric oxide synthesis but has no effect on the severity of experimental colitis.
Topics: Administration, Oral; Animals; Colitis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Reference Values; Severity of Illness Index; Statistics, Nonparametric; Trinitrobenzenesulfonic Acid | 2000 |
Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation in synthetic diet-fed rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Captopril; Cardiac Glycosides; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Gene Expression; Imidazoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Weight Gain | 2000 |
Involvement of potassium channels in the protective effect of 17beta-estradiol on hypercholesterolemic rabbit carotid artery.
Topics: Acetylcholine; Analysis of Variance; Animals; Biological Factors; Carotid Arteries; Cholesterol; Culture Techniques; Disease Models, Animal; Drug Interactions; Estradiol; Hypercholesterolemia; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Potassium Channels; Probability; Rabbits; Random Allocation; Reference Values; Vasoconstriction; Vasodilation | 2000 |
Evaluation of oxidative stress in experimental colitis: effects of L-arginine-nitric oxide pathway manipulation.
Topics: Analysis of Variance; Animals; Arginine; Colitis; Colon; Disease Models, Animal; Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Trinitrobenzenesulfonic Acid | 2000 |
Effect of L-arginine on endothelial injury and hemostasis in rabbit endotoxin shock.
Topics: Acetylcholine; Animals; Arginine; Blood Gas Analysis; Calcimycin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hemostasis; Ionophores; Lipopolysaccharides; Male; Monocytes; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenylephrine; Rabbits; Shock, Septic; Thromboplastin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Weight Loss | 2000 |
Role of monocyte chemoattractant protein-1 in cardiovascular remodeling induced by chronic blockade of nitric oxide synthesis.
Topics: Animals; Antibodies, Monoclonal; Blood Pressure; Cell Division; Chemokine CCL2; Chronic Disease; Collagen; Coronary Artery Disease; Dermis; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Inflammation; Male; Monocytes; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Recombinant Proteins; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling | 2000 |
Role of nitric oxide and endothelin-1 in a portal hypertensive rat model.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Guanidines; Hypertension, Portal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Portal Vein; Rats; Rats, Sprague-Dawley | 2000 |
New method for imaging innervation of the renal preglomerular vasculature. Alterations in hypertensive rats.
Topics: Adrenergic Fibers; Angiotensin II; Animals; Arteries; Disease Models, Animal; Hypertension; Immunohistochemistry; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Synaptophysin | 2000 |
Evaluation of low-dose endotoxin administration during pregnancy as a model of preeclampsia.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Endotoxins; Enzyme Inhibitors; Female; Kidney; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley | 2000 |
Gastric mucosal resistance to acute injury in experimental portal hypertension.
Topics: Anesthesia; Animals; Common Bile Duct; Disease Models, Animal; Enzyme Inhibitors; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Hypertension, Portal; Isoenzymes; Ligation; Liver Cirrhosis, Biliary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer Hemorrhage; Portal Vein; Prostaglandins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Increased L-arginine uptake and inducible nitric oxide synthase activity in aortas of rats with heart failure.
Topics: Animals; Aorta; Arginine; Blood Pressure; Disease Models, Animal; DNA Primers; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart Failure; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Tritium; Tumor Necrosis Factor-alpha; Ventricular Pressure | 2001 |
The NO donor molsidomine reduces endothelin-1 gene expression in chronic hypoxic rat lungs.
Topics: Animals; Chronic Disease; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Glyceraldehyde-3-Phosphate Dehydrogenases; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger; Vasodilator Agents | 2001 |
Mechanisms of the increased pressor response to vasopressors in the mesenteric bed of nitric oxide-deficient hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mesentery; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Chloride; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation; Verapamil | 2001 |
Inhibition of neointima by angiotensin-converting enzyme inhibitor in porcine coronary artery balloon-injury model.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Northern; Bradykinin; Catheterization; Coronary Disease; Coronary Vessels; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hepatocyte Growth Factor; Male; NG-Nitroarginine Methyl Ester; Perindopril; RNA, Messenger; Swine; Swine, Miniature; Tunica Intima; Vasodilation | 2001 |
The selective adenosine A1 receptor antagonist KW-3902 prevents radiocontrast media-induced nephropathy in rats with chronic nitric oxide deficiency.
Topics: Animals; Blood Pressure; Contrast Media; Diatrizoate; Disease Models, Animal; Diuretics; Diuretics, Osmotic; Enzyme Inhibitors; Glomerular Filtration Rate; Male; Mannitol; Nephrosis, Lipoid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Sodium; Xanthines | 2001 |
The timing of endothelin and nitric oxide inhibition affects survival in a mice model of septic shock.
Topics: Animals; Antihypertensive Agents; Bosentan; Canavanine; Disease Models, Animal; Endothelin Receptor Antagonists; Endotoxins; Enzyme Inhibitors; Guanidines; Lipopolysaccharides; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Shock, Septic; Sulfonamides; Survival Rate | 2001 |
Effect of prolonged nitric oxide synthesis inhibition on plasma fibrinogen concentration in rats.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Fibrinogen; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Tetrazoles | 2001 |
1,8-cineol, a food flavoring agent, prevents ethanol-induced gastric injury in rats.
Topics: Administration, Oral; Alcoholism; Animals; Antioxidants; Cyclohexanols; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanol; Eucalyptol; Flavoring Agents; Gastric Juice; Gastritis; Male; Menthol; Monoterpenes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Terpenes | 2001 |
Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Chronic Disease; Circadian Rhythm; Disease Models, Animal; Endothelin-1; Gene Expression Regulation, Enzymologic; Hypoxia; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Rats; Rats, Sprague-Dawley; Sleep Apnea Syndromes; Telemetry; Transcription, Genetic; Vasodilation | 2001 |
The role of nitric oxide on cigarette smoke-induced programmed cell death in the gastric mucosa.
Topics: Analysis of Variance; Animals; Apoptosis; Cells, Cultured; Chloroform; Disease Models, Animal; Epithelial Cells; Gastric Mucosa; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Smoking | 2001 |
Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: comparison with protein kinase C.
Topics: Amides; Animals; Basilar Artery; Blood Pressure; Cerebral Arteries; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; Species Specificity; Vasodilator Agents; Vasomotor System | 2001 |
Inhibition of nitric oxide improves coronary perfusion pressure and return of spontaneous circulation in a porcine cardiopulmonary resuscitation model.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cardiopulmonary Resuscitation; Coronary Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Countershock; Female; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prospective Studies; Random Allocation; Survival Analysis; Swine; Time Factors; Ventricular Fibrillation | 2001 |
Angiotensin converting enzyme inhibitor restrains inflammation-induced vascular injury in mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Disease Models, Animal; Enzyme Inhibitors; Femoral Artery; Gene Expression; Inflammation; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Perindopril; RNA, Messenger | 2001 |
Contribution of nitric oxide to the protective effects of ischemic preconditioning in ischemia-reperfused rat kidneys.
Topics: Animals; Arginine; Blood Pressure; Caspase 3; Caspases; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Ischemic Preconditioning; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reperfusion Injury; Sodium | 2001 |
Nitric oxide synthase inhibition attenuates vasoactive response to spinal cord stimulation in an experimental cerebral vasospasm model.
Topics: Animals; Blood Flow Velocity; Carotid Artery, Internal; Cerebrovascular Circulation; Disease Models, Animal; Electric Stimulation Therapy; Female; Male; NG-Nitroarginine Methyl Ester; Oximetry; Rabbits; Spinal Cord; Subarachnoid Hemorrhage; Ultrasonography, Doppler, Transcranial; Vasodilation; Vasospasm, Intracranial | 2001 |
Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats.
Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Cardiomyopathies; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Pravastatin; Rats; Rats, Wistar; Thromboxane B2 | 2001 |
The role of the interaction between endogenous opioids and nitric oxide in the pathophysiology of ethanol-induced gastric damage in cholestatic rats.
Topics: Alcohol Deterrents; Animals; Arginine; Bile Ducts; Cholestasis; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Ligation; Male; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Opioid Peptides; Rats; Stomach Ulcer | 2001 |
The role of nitric oxide in the gastric acid secretion induced by ischemia-reperfusion in the pylorus-ligated rat.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Gastric Acid; Gastric Mucosa; Ligation; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Penicillamine; Pylorus; Rats; Rats, Inbred Strains; Reperfusion Injury; Stomach; Stomach Ulcer; Superoxide Dismutase; Time Factors | 2001 |
Compensated heart failure predisposes to outer medullary tubular injury: studies in rats.
Topics: Acute Kidney Injury; Animals; Cardiomegaly; Cardiovascular Agents; Disease Models, Animal; Enzyme Inhibitors; Heart Failure; Hypoxia; Indomethacin; Kidney Medulla; Kidney Tubular Necrosis, Acute; Loop of Henle; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction; Vasodilation | 2001 |
Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation.
Topics: Animals; Blotting, Western; Cerebellum; Disease Models, Animal; Enzyme Inhibitors; Glucose; Hypoxia-Ischemia, Brain; Immunohistochemistry; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Purkinje Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Tyrosine | 2001 |
Changes in vascular reactivity induced by acute hyperthyroidism in isolated rat aortae.
Topics: Acetylcholine; Acute Disease; Animals; Aorta; Blood Pressure; Blotting, Western; Body Weight; Cardiovascular Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hyperthyroidism; Male; Muscle Relaxation; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Rats; Rats, Wistar; Stimulation, Chemical; Thyroxine; Triiodothyronine; Vasoconstriction | 2000 |
Potentiated endothelium-derived hyperpolarizing factor-mediated dilations in cerebral arteries following mild head injury.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Biological Factors; Brain Injuries; Charybdotoxin; Dilatation, Pathologic; Disease Models, Animal; Endothelium, Vascular; Indomethacin; Male; Middle Cerebral Artery; NG-Nitroarginine Methyl Ester; Rats; Rats, Long-Evans; Time Factors | 2001 |
N-acetyl-L-cysteine improves renal medullary hypoperfusion in acute renal failure.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Flow Velocity; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Glomerular Filtration Rate; Kidney Medulla; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury; Vena Cava, Inferior | 2001 |
Inhibition of nitric oxide synthesis by L-name exacerbates acute lung injury induced by hepatic ischemia-reperfusion.
Topics: Alanine Transaminase; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibitors; Interleukin-1; Leukocyte Count; Liver; Lung; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Proteins; Rats; Rats, Inbred F344; Reperfusion Injury; Superoxides; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha | 2001 |
Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis.
Topics: Animals; Anti-Inflammatory Agents; Arteriosclerosis; Blood Pressure; Chemokine CCL2; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Lipids; Macrophages; Male; Monocytes; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Peptidyl-Dipeptidase A; Pravastatin; Proliferating Cell Nuclear Antigen; Pyridines; Rats; Rats, Inbred WKY; rhoA GTP-Binding Protein; RNA, Messenger; Systole; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Role of nitric oxide in regulation of coronary blood flow in response to increased metabolic demand in dogs with pacing-induced heart failure.
Topics: Animals; Cardiomyopathy, Dilated; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Energy Metabolism; Enzyme Inhibitors; Heart Failure; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Pacemaker, Artificial; Vasodilation | 2001 |
Intestinal motility in an in vivo rat model of intestinal ischemia-reperfusion with special reference to the effects of nitric oxide on the motility changes.
Topics: Animals; Disease Models, Animal; Duodenum; Enzyme Inhibitors; Gastrointestinal Motility; Isothiuronium; Jejunum; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury | 2001 |
[Effects of nitric oxide and prostaglandin on gastric mucosal perfusion in rats with portal hypertensive gastropathy].
Topics: Animals; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Gastric Mucosa; Hypertension, Portal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Portal Pressure; Prostaglandins; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2001 |
Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of L-NAME on symptom progression.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Disease Models, Animal; Enzyme Inhibitors; Female; Huntington Disease; Immunohistochemistry; Male; Mice; Mice, Transgenic; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Tyrosine | 2001 |
Arteriogenesis and angiogenesis in rat ischemic hindlimb: role of nitric oxide.
Topics: Animals; Arterioles; Capillaries; Disease Models, Animal; Enzyme Inhibitors; Hindlimb; Ischemia; Kidney; Male; Muscle, Skeletal; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peripheral Vascular Diseases; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2001 |
Renal effects of nitric oxide in endotoxemia.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Endotoxemia; Female; Glomerular Filtration Rate; Isothiuronium; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Renal Circulation; Resuscitation; Shock, Septic; Swine | 2001 |
Decreased expression of myocardial eNOS and caveolin in dogs with hypertrophic cardiomyopathy.
Topics: Animals; Cardiomyopathy, Hypertrophic; Caveolin 1; Caveolins; Coronary Circulation; Disease Models, Animal; Dogs; Echocardiography; Hemodynamics; Hypertension, Renal; Immunoblotting; Immunohistochemistry; Mesenteric Arteries; Microcirculation; Muscle Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Regression Analysis; Ventricular Function, Left | 2002 |
Prior exercise training produces NO-dependent increases in collateral blood flow after acute arterial occlusion.
Topics: Analysis of Variance; Animals; Arterial Occlusive Diseases; Body Weight; Disease Models, Animal; Femoral Artery; Injections, Intra-Arterial; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Conditioning, Animal; Physical Exertion; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vascular Resistance | 2002 |
Effects of intracavernous administration of adrenomedullin on erectile function in rats.
Topics: Adrenomedullin; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Erectile Dysfunction; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Peptides; Phosphodiesterase Inhibitors; Piperidines; Quinazolines; Rats; Rats, Wistar | 2001 |
N(omega) -nitro-L-arginine methyl ester (L-NAME) attenuates the acute inflammatory responses and brain injury during the early phase of experimental Escherichia coli meningitis in the newborn piglet.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain Chemistry; Disease Models, Animal; Enzyme Inhibitors; Glucose; Intracranial Pressure; Lactic Acid; Leukocyte Count; Lipid Peroxidation; Meningitis, Escherichia coli; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxyhemoglobins; Sodium-Potassium-Exchanging ATPase; Spectroscopy, Near-Infrared; Swine; Tumor Necrosis Factor-alpha | 2001 |
Adaptive cytoprotection against acetic acid induced colonic injury in rats.
Topics: Acetic Acid; Animals; Colon; Colonic Diseases; Culture Techniques; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Probability; Rats; Rats, Inbred F344; Reference Values; Sensitivity and Specificity | 2001 |
[The role of endogenous nitric oxide in airway hyperresponsiveness of asthmatic rats].
Topics: Animals; Arginine; Asthma; Disease Models, Animal; Enzyme Inhibitors; Hypersensitivity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar | 1999 |
Role of nitric oxide in a progressive neurodegeneration model of Parkinson's disease in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Enzyme Inhibitors; Homovanillic Acid; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2001 |
Effects of oxygen and glucose deprivation on the expression and distribution of neuronal and inducible nitric oxide synthases and on protein nitration in rat cerebral cortex.
Topics: Animals; Blotting, Western; Brain Ischemia; Calcium; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Glucose; Hypoxia; Immunohistochemistry; Magnetic Resonance Imaging; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Rats, Wistar; Reperfusion Injury; Tyrosine | 2002 |
L-tryptophan-L-kynurenine pathway metabolism accelerated by Toxoplasma gondii infection is abolished in gamma interferon-gene-deficient mice: cross-regulation between inducible nitric oxide synthase and indoleamine-2,3-dioxygenase.
Topics: Animals; Antigens, Protozoan; Antigens, Surface; Brain; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protozoan Proteins; RNA, Messenger; Toxoplasma; Toxoplasmosis; Tryptophan; Tryptophan Oxygenase | 2002 |
Inhibition of nitric oxide synthase does not influence urinary nitrite plus nitrate excretion after renal ischemic injury.
Topics: Animals; Disease Models, Animal; Ischemia; Kidney; Kidney Tubules; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Circulation; Reperfusion Injury; Time Factors | 2002 |
Therapeutic administration of nitric oxide synthase inhibitors reverses hyperalgesia but not inflammation in a rat model of polyarthritis.
Topics: Animals; Arthritis; Body Weight; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Female; Hot Temperature; Hyperalgesia; Indomethacin; Lysine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Physical Stimulation; Rats; Rats, Inbred Lew | 2002 |
The effect of nitric oxide synthesis inhibition on intravenous cocaine self-administration.
Topics: Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Long-Evans; Reward; Self Administration | 2002 |
Vascular endothelial growth factor is necessary in the development of arteriosclerosis by recruiting/activating monocytes in a rat model of long-term inhibition of nitric oxide synthesis.
Topics: Animals; Arteriosclerosis; Biological Assay; Blood Pressure; Cell Division; Chemokine CCL2; Chemotaxis, Leukocyte; Coronary Vessels; Disease Models, Animal; Endothelial Growth Factors; Enzyme Inhibitors; Gene Expression; Gene Transfer, Horizontal; Genetic Vectors; Inflammation; Injections, Intramuscular; Lymphokines; Male; Mice; Monocytes; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins; Rats; Rats, Inbred WKY; Receptor Protein-Tyrosine Kinases; RNA, Messenger; Time; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 2002 |
Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading.
Topics: Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Eplerenone; Heart Diseases; Male; Mineralocorticoid Receptor Antagonists; NG-Nitroarginine Methyl Ester; Potassium; Rats; Rats, Wistar; Spironolactone | 2002 |
The additive effect of opioids and nitric oxide in increasing pentylenetetrazole-induced seizure threshold in cholestatic mice.
Topics: Animals; Cholestasis; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures | 2002 |
Red blood cell rheological properties in various rat hypertension models.
Topics: Animals; Aorta, Abdominal; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Hemorheology; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; NG-Nitroarginine Methyl Ester; Platelet Aggregation; Rats | 2002 |
The impact of insulin-like growth factor-1 on the pattern of cardiac elongation factor-2 variants in a model of overload.
Topics: Animals; Apoptosis; Body Weight; Cardiomegaly; Disease Models, Animal; DNA Fragmentation; Enzyme Inhibitors; Genetic Variation; Heart; Hemodynamics; Hypertension; Insulin-Like Growth Factor I; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Elongation Factor 2; Rats; Rats, Wistar | 2002 |
Myocardial dysfunction with coronary microembolization: signal transduction through a sequence of nitric oxide, tumor necrosis factor-alpha, and sphingosine.
Topics: Amidohydrolases; Animals; Apoptosis; Blood Flow Velocity; Ceramidases; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Embolism; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Leukocyte Count; Microspheres; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oleic Acids; RNA, Messenger; Signal Transduction; Sphingosine; Tumor Necrosis Factor-alpha | 2002 |
Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Eating; Enzyme Inhibitors; Hypertriglyceridemia; Insulin; Lipid Metabolism; Lipids; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Obesity; Postprandial Period; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Species Specificity; Time | 2002 |
Differential effects of selective and non-selective NOS inhibition on renal arginine and protein metabolism during endotoxemia in rats.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Isothiuronium; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Biosynthesis; Proteins; Random Allocation; Rats; Rats, Wistar; Sepsis; Specific Pathogen-Free Organisms | 2002 |
Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Collagen; Cyclooxygenase 2; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Endothelial Growth Factors; Female; Imidazoles; Isoenzymes; Laminin; Lymphokines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfonamides; Tetrazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
The neuroprotective effect of a nitric oxide inhibitor in a rat model of focal cerebral ischaemia.
Topics: Amino Acid Oxidoreductases; Anesthesia; Animals; Arginine; Blood Pressure; Brain Ischemia; Disease Models, Animal; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred Strains | 1992 |
Inhibition of nitric oxide synthesis does not reduce infarct volume in a rat model of focal cerebral ischaemia.
Topics: Animals; Arginine; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain Ischemia; Cell Death; Cerebral Arteries; Cerebral Infarction; Disease Models, Animal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley | 1992 |